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1

Effect of glycogen synthase kinase-3 inactivation on mouse mammary gland development and oncogenesis

Dembowy, J, Adissu, H A, Liu, J C, Zacksenhaus, E, Woodgett, J R

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 5.87 MB

english, 2015

2

pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis.

Zacksenhaus, E, Jiang, Z, Chung, D, Marth, J D, Phillips, R A, Gallie, B L

Journal:

Genes & Development

Année:

1996

Langue:

english

Fichier:

PDF, 21.20 MB

english, 1996

3

Dynamic regulation of the Stra13/Sharp/Dec bHLH repressors in mammary epithelium

Benoit St-Pierre, Melissa Cooper, Zhe Jiang, Eldad Zacksenhaus, Sean E. Egan

Journal:

Developmental Dynamics

Année:

2004

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2004

4

Mapping and expression of the ubiquitin-activating enzyme E1 (Ube1) gene in the mouse

Christine M. Disteche, Eldad Zacksenhaus, David A. Adler, Steven L. Bressler, Bernadette T. Keitz, Verne M. Chapman

Journal:

Mammalian Genome

Année:

1992

Langue:

english

Fichier:

PDF, 746 KB

english, 1992

5

Coupling of caspase-9 to Apaf1 in response to loss of pRb or cytotoxic drugs is cell-type-specific

Ho, Andrew T, Li, Qin H, Hakem, Razqallah, Mak, Tak W, Zacksenhaus, Eldad

Journal:

The EMBO Journal

Année:

2004

Langue:

english

Fichier:

PDF, 1018 KB

english, 2004

6

The retinoblastoma gene family is differentially expressed during embryogenesis

Jiang, Zhe, Zacksenhaus, Eldad, Gallie, Brenda L, Phillips, Robert A

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 1.93 MB

english, 1997

7

E2F1 mediates ectopic proliferation and stage-specific p53-dependent apoptosis but not aberrant differentiation in the ocular lens of Rb deficient fetuses

Liu, Yule, Zacksenhaus, Eldad

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 692 KB

english, 2000

8

Identification of human gene complementing ts AlS9 mouse L-cell defect in DNA replication following DNA-mediated gene transfer

Eldad Zacksenhaus, Rose Sheinin

Journal:

Somatic Cell and Molecular Genetics

Année:

1988

Langue:

english

Fichier:

PDF, 779 KB

english, 1988

9

Molecular cloning of human A1S9 locus: An X-linked gene essential for progression through S phase of the cell cycle

Eldad Zacksenhaus, Rose Sheinin

Journal:

Somatic Cell and Molecular Genetics

Année:

1989

Langue:

english

Fichier:

PDF, 1.01 MB

english, 1989

10

High expression during neurogenesis but not mammogenesis of a murine homologue of the Deleted in Breast Cancer2/Rhobtb2 tumor suppressor

Benoit St-Pierre, Zhe Jiang, Sean E. Egan, Eldad Zacksenhaus

Journal:

Gene Expression Patterns

Année:

2004

Langue:

english

Fichier:

PDF, 535 KB

english, 2004

11

RETRACTED: Coordinated expression of Rb gene family in the mammary gland

Zhe Jiang, Eldad Zacksenhaus

Journal:

Gene Expression Patterns

Année:

2002

Langue:

english

Fichier:

PDF, 525 KB

english, 2002

12

E2F1 and p53 Are Dispensable, whereas p21Waf1/Cip1 Cooperates with Rb to Restrict Endoreduplication and Apoptosis during Skeletal Myogenesis

Zhe Jiang, Ping Liang, Roger Leng, Zhong Guo, Yule Liu, Xudong Liu, Simon Bubnic, Armand Keating, David Murray, Paul Goss, Eldad Zacksenhaus

Journal:

Developmental Biology

Année:

2000

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2000

13

Nuclear localization conferred by the pocket domain of the retinoblastoma gene product

Eldad Zacksenhaus, Zhe Jiang, Yong J. Hei, Robert A. Phillips, Brenda L. Gallie

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Année:

1999

Langue:

english

Fichier:

PDF, 573 KB

english, 1999

14

Coordinated expression of Rb gene family in the mammary gland

Zhe Jiang, Eldad Zacksenhaus

Journal:

Mechanisms of Development

Année:

2002

Langue:

english

Fichier:

PDF, 517 KB

english, 2002

15

Identification of Tumorsphere- and Tumor-Initiating Cells in HER2/Neu-Induced Mammary Tumors

Liu, J. C., Deng, T., Lehal, R. S., Kim, J., Zacksenhaus, E.

Journal:

Cancer Research

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

16

The ets transcription factor Fli-1 in development, cancer and disease

Li, Y, Luo, H, Liu, T, Zacksenhaus, E, Ben-David, Y

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2015

17

A novel IFNγ-stimulated gene signature is predictive of the survival and chemotherapy responsiveness of breast cancer patients

El Hassan, Mohamed Abou, Huang, Katherine, Liu, Jeffrey, Yu, Tao, Zacksenhaus, Eldad, Bremner, Rod

Journal:

Clinical Biochemistry

Année:

2014

Langue:

english

Fichier:

PDF, 50 KB

english, 2014

18

shRNA Kinome Screen Identifies TBK1 as a Therapeutic Target for HER2+ Breast Cancer

Deng, T., Liu, J. C., Chung, P. E. D., Uehling, D., Aman, A., Joseph, B., Ketela, T., Jiang, Z., Schachter, N. F., Rottapel, R., Egan, S. E., Al-awar, R., Moffat, J., Zacksenhaus, E.

Journal:

Cancer Research

Année:

2014

Langue:

english

Fichier:

PDF, 2.81 MB

english, 2014

19

Seventeen-gene signature from enriched Her2/Neu mammary tumor-initiating cells predicts clinical outcome for human HER2+:ER - breast cancer

Liu, J. C., Voisin, V., Bader, G. D., Deng, T., Pusztai, L., Symmans, W. F., Esteva, F. J., Egan, S. E., Zacksenhaus, E.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2012

20

Combined deletion of Pten and p53 in mammary epithelium accelerates triple-negative breast cancer with dependency on eEF2K

Liu, J. C., Voisin, V., Wang, S., Wang, D.-Y., Jones, R. A., Datti, A., Uehling, D., Al-awar, R., Egan, S. E., Bader, G. D., Tsao, M., Mak, T. W., Zacksenhaus, E.

Journal:

EMBO Molecular Medicine

Année:

2014

Langue:

english

Fichier:

PDF, 3.97 MB

english, 2014

21

Timing is everything: Rb’s choice in islet-cell fate

Cai, Erica P, Wu, Xiaohong, Zacksenhaus, Eldad, Woo, Minna

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 262 KB

english, 2014

22

RB1 and p53 at the crossroad of EMT and triple-negative breast cancer

Jiang, Zhe, Jones, Robert, Liu, Jeff C., Deng, Tao, Robinson, Tyler, Chung, Philip E.D., Wang, Sharon, Herschkowitz, Jason I., Egan, Sean E., Perou, Charles M., Zacksenhaus, Eldad

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2011

23

High-throughput screen identifies disulfiram as a potential therapeutic for triple-negative breast cancer cells: Interaction with IQ motif-containing factors

Robinson, Tyler, Pai, Melody, Liu, Jeff, Vizeacoumar, Frederick, Sun, Thomas, Egan, Sean, Datti, Alessandro, Huang, Jing, Zacksenhaus, Eldad

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 6.18 MB

english, 2013

24

Retinoblastoma tumor suppressor protein in pancreatic progenitors controls α- and β-cell fate

Cai, Erica P., Wu, Xiaohong, Schroer, Stephanie A., Elia, Andrew J., Nostro, M. Cristina, Zacksenhaus, Eldad, Woo, Minna

Journal:

Proceedings of the National Academy of Sciences

Année:

2013

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2013

25

Retinoblastoma Gene Promoter Directs Transgene Expression Exclusively to the Nervous System

Jiang, Z., Guo, Z., Saad, F. A., Ellis, J., Zacksenhaus, E.

Journal:

Journal of Biological Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2001

26

Cyclins, Cdks, E2f, Skp2, and More at the First International RB Tumor Suppressor Meeting

Bremner, R., Zacksenhaus, E.

Journal:

Cancer Research

Année:

2010

Langue:

english

Fichier:

PDF, 186 KB

english, 2010

27

Rescue of myogenic defects in Rb-deficient cells by inhibition of autophagy or by hypoxia-induced glycolytic shift

Ciavarra, G., Zacksenhaus, E.

Journal:

The Journal of Cell Biology

Année:

2010

Langue:

english

Fichier:

PDF, 3.53 MB

english, 2010

28

mda-7/IL-24 Expression Inhibits Breast Cancer through Upregulation of Growth Arrest-Specific Gene 3 (gas3) and Disruption of 1 Integrin Function

Li, Y.-J., Liu, G., Li, Y., Vecchiarelli-Federico, L. M., Liu, J. C., Zacksenhaus, E., Shan, S. W., Yang, B. B., Li, Q., Dash, R., Fisher, P. B., Archer, M. C., Ben-David, Y.

Journal:

Molecular Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.89 MB

english, 2013

29

Preferential Killing of Breast Tumor Initiating Cells by N,N-Diethyl-2-[4-(Phenylmethyl)Phenoxy]Ethanamine/Tesmilifene

Deng, T., Liu, J. C., Pritchard, K. I., Eisen, A., Zacksenhaus, E.

Journal:

Clinical Cancer Research

Année:

2009

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2009

30

Rb and p107 are required for alpha cell survival, beta cell cycle control and glucagon-like peptide-1 action

Cai, Erica P., Luk, Cynthia T., Wu, Xiaohong, Schroer, Stephanie A., Shi, Sally Yu, Sivasubramaniyam, Tharini, Brunt, Jara J., Zacksenhaus, Eldad, Woo, Minna

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1009 KB

english, 2014

31

XIAP Activity Dictates Apaf-1 Dependency for Caspase 9 Activation

Ho, A. T., Li, Q. H., Okada, H., Mak, T. W., Zacksenhaus, E.

Journal:

Molecular and Cellular Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2007

32

Cooperation between Pik3ca and p53 Mutations in Mouse Mammary Tumor Formation

Adams, J. R., Xu, K., Liu, J. C., Agamez, N. M. R., Loch, A. J., Wong, R. G., Wang, W., Wright, K. L., Lane, T. F., Zacksenhaus, E., Egan, S. E.

Journal:

Cancer Research

Année:

2011

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2011

33

Multiple pathways counteract cell death induced by RB1 loss: Implications for cancer

Ciavarra, Giovanni, Zacksenhaus, Eldad

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 2.05 MB

english, 2011

34

Activation of Retinoblastoma Protein in Mammary Gland Leads to Ductal Growth Suppression, Precocious Differentiation, and Adenocarcinoma

Zhe Jiang and Eldad Zacksenhaus

Journal:

The Journal of Cell Biology

Année:

2002

Langue:

english

Fichier:

PDF, 3.74 MB

english, 2002

35

Splitting the Apoptosome

Ho, Andrew T., Zacksenhaus, Eldad

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 393 KB

english, 2004

36

Direct and indirect effects of the pRb tumor suppressor on autophagy

Ciavarra, Giovanni, Zacksenhaus, Eldad

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2011

37

Alternative Reading Frame Supports An Alternative Model for Retinoblastoma

Zacksenhaus, Eldad

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 340 KB

english, 2003

38

Targeted Pten deletion plus p53-R270H mutation in mouse mammary epithelium induces aggressive claudin-low and basal-like breast cancer

Wang, Sharon, Liu, Jeff C., Kim, Danbi, Datti, Alessandro, Zacksenhaus, Eldad

Journal:

Breast Cancer Research

Année:

2016

Langue:

english

Fichier:

PDF, 2.58 MB

english, 2016

39

Fli-1, an Ets-Related Transcription Factor, Regulates Erythropoietin-Induced Erythroid Proliferation and Differentiation: Evidence for Direct Transcriptional Repression of the Rb Gene during Differentiation

Tamir, Ami, Howard, Jeff, Higgins, Rachel R., Li, You-Jun, Berger, Lloyd, Zacksenhaus, Eldad, Reis, Marciano, Ben-David, Yaacov

Journal:

Molecular and Cellular Biology

Année:

1999

Langue:

english

Fichier:

PDF, 14.65 MB

english, 1999

40

Phosphorylated STAT5 regulates p53 expression via BRCA1/BARD1-NPM1 and MDM2

Ren, Zhuo, Aerts, Joeri L, Vandenplas, Hugo, Wang, Jiance A, Gorbenko, Olena, Chen, Jack P, Giron, Philippe, Heirman, Carlo, Goyvaerts, Cleo, Zacksenhaus, Eldad, Minden, Mark D, Stambolic, Vuk, Breckp

Journal:

Cell Death and Disease

Année:

2016

Langue:

english

Fichier:

PDF, 2.45 MB

english, 2016

41

[Advances in Cancer Research] Volume 61 || Unraveling the Function of the Retinoblastoma Gene

Zacksenhaus, Eldad

Année:

1993

Langue:

english

Fichier:

PDF, 1.45 MB

english, 1993

42

Coactosin-like protein CLP/Cotl1 suppresses breast cancer growth through activation of IL-24/PERP and inhibition of non-canonical TGFβ signaling

Xia, L, Xiao, X, Liu, W L, Song, Y, Liu, T J J, Li, Y J, Zacksenhaus, E, Hao, X J, Ben-David, Y

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 1.99 MB

english, 2017

43

Mitochondrial OXPHOS Induced by RB1 Deficiency in Breast Cancer: Implications for Anabolic Metabolism, Stemness, and Metastasis

Zacksenhaus, Eldad, Shrestha, Mariusz, Liu, Jeff C., Vorobieva, Ioulia, Chung, Philip E.D., Ju, YoungJun, Nir, Uri, Jiang, Zhe

Journal:

Trends in Cancer

Année:

2017

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2017

44

Critical Role of the Rb Family in Myoblast Survival and Fusion

Ciavarra, Giovanni, Ho, Andrew T., Cobrinik, David, Zacksenhaus, Eldad, Vooijs, Marc

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 3.02 MB

english, 2011

45

Cancer Cells Hijack PRC2 to Modify Multiple Cytokine Pathways

Abou El Hassan, Mohamed, Huang, Katherine, Eswara, Manoja B. K., Zhao, Michael, Song, Lan, Yu, Tao, Liu, Yu, Liu, Jeffrey C., McCurdy, Sean, Ma, Anqi, Wither, Joan, Jin, Jian, Zacksenhaus, Eldad, Wran

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 7.74 MB

english, 2015

46

Identification of cell proliferation, immune response and cell migration as critical pathways in a prognostic signature for HER2+:ERα- breast cancer

Liu, Jeffrey C., Zacksenhouse, Miriam, Eisen, Andrea, Nofech-Mozes, Sharon, Zacksenhaus, Eldad, Ahmad, Aamir

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 12.79 MB

english, 2017

47

[Advances in Protein Chemistry and Structural Biology] Chromatin Proteins and Transcription Factors as Therapeutic Targets Volume 107 || Transcription Factors in Breast Cancer—Lessons From Recent Genomic Analyses and Therapeutic Implications

Zacksenhaus, E.

Année:

2017

Langue:

english

Fichier:

PDF, 4.55 MB

english, 2017

48

Associations Between XPD Lys751Gln Polymorphism and Leukemia: A Meta-Analysis

Wen, Min, Zhou, Bo, Lin, Xin, Chen, Yunhua, Song, Jialei, Li, Yanmei, Zacksenhaus, Eldad, Ben-David, Yaacov, Hao, Xiaojiang

Journal:

Frontiers in Genetics

Année:

2018

Langue:

english

Fichier:

PDF, 13.94 MB

english, 2018

49

CDC25 as a common therapeutic target for triple-negative breast cancer - the challenges ahead

Zacksenhaus, Eldad, Liu, Jeff C., Granieri, Letizia, Vorobieva, Ioulia, Wang, Dong-Yu, Ghanbari-Azarnier, Ronak, Li, Huiqin, Ali, Amjad, Chung, Philip E.D., Ju, YoungJun, Jiang, Zhe, Shrestha, Mariusz

Journal:

Molecular & Cellular Oncology

Année:

2018

Langue:

english

Fichier:

PDF, 1.85 MB

english, 2018

50

Novel flavagline-like compounds with potent Fli-1 inhibitory activity suppress diverse types of leukemia

Song, Jialei, Yuan, Chunmao, Yang, Jue, Liu, Tangjingjun, Yao, Yao, Xiao, Xiao, Gajendran, Babu, Xu, Dahai, Li, You-Jun, Wang, Chunlin, Liu, Wuling, Wen, Min, Spaner, David, Filmus, Jorge, Zacksenhaus

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2018