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1

Alzheimer's Disease: New Light on Etiology and Management

Nikolaos K. Robakis

Journal:

Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine

Année:

2010

Langue:

english

Fichier:

PDF, 58 KB

english, 2010

2

Cellular mechanisms of γ-secretase substrate selection, processing and toxicity

Gael Barthet, Anastasios Georgakopoulos, Nikolaos K. Robakis

Journal:

Progress in Neurobiology

Année:

2012

Langue:

english

Fichier:

PDF, 1.56 MB

english, 2012

3

Head tremor in essential tremor: “Yes–yes”, “no–no”, or “round and round”?

Robakis, Daphne, Louis, Elan D.

Journal:

Parkinsonism & Related Disorders

Année:

2016

Langue:

english

Fichier:

PDF, 197 KB

english, 2016

4

Classification of producer characteristics in primate long calls using neural networks

Robakis, Efstathia, Watsa, Mrinalini, Erkenswick, Gideon

Journal:

The Journal of the Acoustical Society of America

Année:

2018

Langue:

english

Fichier:

PDF, 612 KB

english, 2018

5

Early life adversity blunts responses to pioglitazone in depressed, overweight adults

Robakis, Thalia K., Watson-Lin, Kathleen, Wroolie, Tonita E., Myoraku, Alison, Nasca, Carla, Bigio, Benedetta, McEwen, Bruce, Rasgon, Natalie L.

Journal:

European Psychiatry

Année:

2019

Langue:

english

Fichier:

PDF, 513 KB

english, 2019

6

Identification and neuron specific expression of the S182/presenilin I protein in human and rodent brains

G.A. Elder, N. Tezapsidis, J. Carter, J. Shioi, C. Bouras, H.-C. Li, J.M. Johnston, S. Efthimiopoulos, V.L. Friedrich Jr., N.K. Robakis

Journal:

Journal of Neuroscience Research

Année:

1996

Langue:

english

Fichier:

PDF, 1.78 MB

english, 1996

7

The Alzheimer's amyloid precursor protein is produced by type I astrocytes in primary cultures of rat neuroglia

F. Berkenbosch, L. M. Refolo, V. L. Friedrich Jr., D. Casper, M. Blum, Dr. Nikolaos K. Robakis

Journal:

Journal of Neuroscience Research

Année:

1990

Langue:

english

Fichier:

PDF, 972 KB

english, 1990

8

Evidence for intracellular cleavage of the Alzheimer's amyloid precursor in PC12 cells

K. Sambamurti, J. Shioi, J. P. Anderson, M. A. Pappolla, Dr. N. K. Robakis

Journal:

Journal of Neuroscience Research

Année:

1992

Langue:

english

Fichier:

PDF, 1.07 MB

english, 1992

9

Study of the phorbol ester effect on Alzheimer amyloid precursor processing: Sequence requirements and involvement of a Cholera toxin sensitive protein

S. Efthimiopoulos, K. M. Felsenstein, K. Sambamurti, N. K. Robakis, L. M. Refolo

Journal:

Journal of Neuroscience Research

Année:

1994

Langue:

english

Fichier:

PDF, 1.13 MB

english, 1994

10

Solubilization of full-length amyloid precursor proteins from PC12 cell membranes

J. A. Ripellino, D. Vassilacopoulou, Dr. N. K. Robakis

Journal:

Journal of Neuroscience Research

Année:

1994

Langue:

english

Fichier:

PDF, 1.11 MB

english, 1994

11

Evidence that secretase cleavage of cell surface Alzheimer amyloid precursor occurs after normal endocytic internalization

Dr. L. M. Refolo, K. Sambamurti, S. Efthimiopoulos, M. A. Pappolla, N. K. Robakis

Journal:

Journal of Neuroscience Research

Année:

1995

Langue:

english

Fichier:

PDF, 2.25 MB

english, 1995

12

Full-Length and Truncated Alzheimer Amyloid Precursors in Chromaffin Granules: Solubilization of Membrane Amyloid Precursor Is Mediated by an Enzymatic Mechanism

Dido Vassilacopoulou, James A. Ripellino, Nikolaos Tezapsidis, Vivian Y. H. Hook, Nikolaos K. Robakis

Journal:

Journal of Neurochemistry

Année:

1995

Langue:

english

Fichier:

PDF, 830 KB

english, 1995

13

Expression of the Chondroitin Sulfate Proteoglycans of Amyloid Precursor (Appican) and Amyloid Precursor-Like Protein 2

Menelas N. Pangalos, Junichi Shioi, Nikolaos K. Robakis

Journal:

Journal of Neurochemistry

Année:

1995

Langue:

english

Fichier:

PDF, 997 KB

english, 1995

14

Intracellular Cyclic AMP Inhibits Constitutive and Phorbol Ester-Stimulated Secretory Cleavage of Amyloid Precursor Protein

Spiros Efthimiopoulos, Suzy Punj, Vangelis Manolopoulos, Menelas Pangalos, Gian P. Wang, Lawrence M. Refolo, Nikolaos K. Robakis

Journal:

Journal of Neurochemistry

Année:

1996

Langue:

english

Fichier:

PDF, 449 KB

english, 1996

15

Enrichment of Presenilin 1 Peptides in Neuronal Large Dense-Core and Somatodendritic Clathrin-Coated Vesicles

Spiros Efthimiopoulos, Erik Floor, Anastasios Georgakopoulos, Junichi Shioi, Wen Cui, Sukkid Yasothornsrikul, Vivian Y. H. Hook, Thomas Wisniewski, Luc Buee, Nikolaos K. Robakis

Journal:

Journal of Neurochemistry

Année:

1998

Langue:

english

Fichier:

PDF, 1000 KB

english, 1998

16

Distinct Secretases, a Cysteine Protease and a Serine Protease, Generate the C Termini of Amyloid β-Proteins Aβ1-40 and Aβ1-42, Respectively

Maria E. Figueiredo-Pereira, Spiros Efthimiopoulos, Nikolaos Tezapsidis, Angeliki Buku, Jorge Ghiso, Pankaj Mehta, Nikolaos K. Robakis

Journal:

Journal of Neurochemistry

Année:

1999

Langue:

english

Fichier:

PDF, 196 KB

english, 1999

17

The mRNA encoding the scrapie agent protein is present in a variety of non-neuronal cells

H. R. Brown, N. L. Goller, R. D. Rudelli, G. S. Merz, G. C. Wolfe, H. M. Wisniewski, N. K. Robakis

Journal:

Acta Neuropathologica

Année:

1990

Langue:

english

Fichier:

PDF, 2.07 MB

english, 1990

18

Deposition of β/A4 protein along neuronal plasma membranes in diffuse senile plaques

A. Probst, D. Langui, S. Ipsen, N. Robakis, J. Ulrich

Journal:

Acta Neuropathologica

Année:

1991

Langue:

english

Fichier:

PDF, 4.10 MB

english, 1991

19

A comparative study of histological and immunohistochemical methods for neurofibrillary tangles and senile plaques in Alzheimer's disease

P. G. Vallet, R. Guntern, P. R. Hof, J. Golaz, A. Delacourte, N. K. Robakis, C. Bouras

Journal:

Acta Neuropathologica

Année:

1992

Langue:

english

Fichier:

PDF, 4.73 MB

english, 1992

20

Presenilin-1 expression in Pick’s disease

P. Giannakopoulos, Enikò Kövari, Luc Buée, Junichi Shioi, Patrick R. Hof, Nikolaos K. Robakis, Constantin Bouras

Journal:

Acta Neuropathologica

Année:

1999

Langue:

english

Fichier:

PDF, 219 KB

english, 1999

21

Phosphatidylinositol-4,5-bisphosphate regulates epidermal growth factor receptor activation

Ioannis E. Michailidis, Radda Rusinova, Anastasios Georgakopoulos, Yibang Chen, Ravi Iyengar, Nikolaos K. Robakis, Diomedes E. Logothetis, Lia Baki

Journal:

Pflügers Archiv European Journal of Physiology

Année:

2011

Langue:

english

Fichier:

PDF, 473 KB

english, 2011

22

The CACNA1C and ANK3 risk alleles impact on affective personality traits and startle reactivity but not on cognition or gating in healthy males

Panos Roussos, Stella G Giakoumaki, Anastasios Georgakopoulos, Nikolaos K Robakis, Panos Bitsios

Journal:

Bipolar Disorders

Année:

2011

Langue:

english

Fichier:

PDF, 161 KB

english, 2011

23

Toxicity of glutathione depletion in mesencephalic cultures: a role for arachidonic acid and its lipoxygenase metabolites

Brian C. Kramer, Jocelyn A. Yabut, Julie Cheong, Ruth Jnobaptiste, Thalia Robakis, C. Warren Olanow, Catherine Mytilineou

Journal:

European Journal of Neuroscience

Année:

2004

Langue:

english

Fichier:

PDF, 228 KB

english, 2004

24

An Alternative Secretase Cleavage Produces Soluble Alzheimer Amyloid Precursor Protein Containing a Potentially Amyloidogenic Sequence

John P. Anderson, Yu Chen, Kwang S. Kim, Nikolaos K. Robakis

Journal:

Journal of Neurochemistry

Année:

1992

Langue:

english

Fichier:

PDF, 436 KB

english, 1992

25

The cytoplasmic sequence of E-cadherin promotes non-amyloidogenic degradation of Aβ precursors

Georgia Agiostratidou, Rosa Miñana Muros, Junichi Shioi, Philippe Marambaud, Nikolaos K. Robakis

Journal:

Journal of Neurochemistry

Année:

2006

Langue:

english

Fichier:

PDF, 234 KB

english, 2006

26

FAD mutants unable to increase neurotoxic Aβ 42 suggest that mutation effects on neurodegeneration may be independent of effects on Aβ

Junichi Shioi, Anastasios Georgakopoulos, Pankaj Mehta, Zen Kouchi, Claudia M. Litterst, Lia Baki, Nikolaos K. Robakis

Journal:

Journal of Neurochemistry

Année:

2007

Langue:

english

Fichier:

PDF, 617 KB

english, 2007

27

Genetic and molecular aspects of Alzheimer's disease shed light on new mechanisms of transcriptional regulation

P. Marambaud, N. K. Robakis

Journal:

Genes, Brain and Behavior

Année:

2005

Langue:

english

Fichier:

PDF, 337 KB

english, 2005

28

Presenilin-1: A Component of Synaptic and Endothelial Adherens Junctions

ANASTASIOS GEORGAKOPOULOS, PHILIPPE MARAMBAUD, VICTOR L. FRIEDRICH JR., JUNICHI SHIOI, SPIROS EFTHIMIOPOULOS, NIKOLAOS K. ROBAKIS

Journal:

Annals of the New York Academy of Sciences

Année:

2000

Langue:

english

Fichier:

PDF, 770 KB

english, 2000

29

The Association of Schizophrenia Risk D-Amino Acid Oxidase Polymorphisms With Sensorimotor Gating, Working Memory and Personality in Healthy Males

Roussos, Panos, Giakoumaki, Stella G, Adamaki, Eva, Anastasios, Georgakopoulos, Nikos, Robakis K, Bitsios, Panos

Journal:

Neuropsychopharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 524 KB

english, 2011

30

PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations

Baki, Lia, Shioi, Junichi, Wen, Paul, Shao, Zhiping, Schwarzman, Alexander, Gama-Sosa, Miguel, Neve, Rachael, Robakis, Nikolaos K

Journal:

The EMBO Journal

Année:

2004

Langue:

english

Fichier:

PDF, 274 KB

english, 2004

31

Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB-induced Src phosphorylation and signaling

Georgakopoulos, Anastasios, Litterst, Claudia, Ghersi, Enrico, Baki, Lia, Xu, ChiJie, Serban, Geo, Robakis, Nikolaos K

Journal:

The EMBO Journal

Année:

2006

Langue:

english

Fichier:

PDF, 412 KB

english, 2006

32

Literature review, case report, and expert discussion of prolonged refractory status epilepticus

T. K. Robakis, L. J. Hirsch

Journal:

Neurocritical Care

Année:

2006

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2006

33

The genetics of Familial Alzheimer’s Disease

Evelyn A. Devine-Gage, Edmund C. Jenkins, W. Ted Brown, Nikolaos K. Robakis, Henryk M. Wisniewski

Journal:

Année:

1988

Langue:

english

Fichier:

PDF, 477 KB

english, 1988

34

The effects of bisulfite on growth and macromolecular synthesis in Escherichia coli

N.K. Robakis, T.G. Rossman, R. Shapiro, W. Szer

Journal:

Chemico-Biological Interactions

Année:

1983

Langue:

english

Fichier:

PDF, 494 KB

english, 1983

35

Reversal of growth inhibition in Escherichia coli by bisulfite

N.K. Robakis, R. Shapiro, W. Szer

Journal:

Chemico-Biological Interactions

Année:

1983

Langue:

english

Fichier:

PDF, 615 KB

english, 1983

36

Syntactic and semantic influences on BOLD signal responses to comprehension of relative clauses

D. Caplan, E. Chen, G. Waters, D. Robakis

Journal:

Brain and Language

Année:

2005

Langue:

english

Fichier:

PDF, 59 KB

english, 2005

37

Overexpression of Wild Type But Not an FAD Mutant Presenilin-1 Promotes Neurogenesis in the Hippocampus of Adult Mice

Paul H. Wen, Xiang Shao, Zhiping Shao, Patrick R. Hof, Thomas Wisniewski, Kevin Kelley, Victor L. Friedrich Jr., Lap Ho, Giulio M. Pasinetti, Junichi Shioi, Nikolaos K. Robakis, Gregory A. Elder

Journal:

Neurobiology of Disease

Année:

2002

Langue:

english

Fichier:

PDF, 561 KB

english, 2002

38

In vitro expression of Escherichia coli ribosomal protein L10 gene: Tripeptide synthesis as a measure of functional mRNA

Yves Cenatiempo, Nikolaos Robakis, Brian R. Reid, Herbert Weissbach, Nathan Brot

Journal:

Archives of Biochemistry and Biophysics

Année:

1982

Langue:

english

Fichier:

PDF, 595 KB

english, 1982

39

Localization of a human gene homologous to the PrP gene on the p ARM of chromosome 20 and detection of PrP-related antigens in normal human brain

Nikolaos K. Robakis, Evelyn A. Devine-Gage, Edmund C. Jenkins, Richard J. Kascsak, W.Ted Brown, Michael S. Krawczun, Wayne P. Silverman

Journal:

Biochemical and Biophysical Research Communications

Année:

1986

Langue:

english

Fichier:

PDF, 1.39 MB

english, 1986

40

Fine mapping of an Alzheimer Disease-associated gene encoding beta-amyloid protein

Edmund C. Jenkins, Evelyn A. Devine-Gage, Nikolaos K. Robakis, Xiu-Lan Yao, W.Ted Brown, George E. Houck Jr., Gloria Wolfe, Narayanarao Ramakrishna, Wayne P. Silverman, Henryk M. Wisniewski

Journal:

Biochemical and Biophysical Research Communications

Année:

1988

Langue:

english

Fichier:

PDF, 745 KB

english, 1988

41

Nerve and epidermal growth factors induce the release of the Alzheimer Amyloid precursor from PC 12 cell cultures

Lawrence M. Refolo, Steven R.J. Salton, John P. Anderson, Pankaj Mehta, Nikolaos K. Robakis

Journal:

Biochemical and Biophysical Research Communications

Année:

1989

Langue:

english

Fichier:

PDF, 1.59 MB

english, 1989

42

Characterization of the 5′-end region and the first two exons of the β-protein precursor gene

Giuseppe La Fauci, Debomoy K. Lahiri, Stephen R.J. Salton, Nikolaos K. Robakis

Journal:

Biochemical and Biophysical Research Communications

Année:

1989

Langue:

english

Fichier:

PDF, 878 KB

english, 1989

43

Binding of vascular heparan sulfate proteoglycan to Alzheimer's amyloid precursor protein is mediated in part by the N-terminal region of A4 peptide

Luc Buée, Wanhong Ding, John P. Anderson, Suree Narindrasorasak, Robert Kisilevsky, Noel J. Boyle, Nikolaos K. Robakis, André Delacourte, Barry Greenberg, Howard M. Fillit

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 609 KB

english, 1993

44

Heat-shock induces abnormalities in the cellular distribution of amyloid precursor protein (APP) and APP fusion proteins

M.A. Pappolla, K. Sambamurti, S. Efthimiopoulos, L. Refolo, R.A. Omar, N.K. Robakis

Journal:

Neuroscience Letters

Année:

1995

Langue:

english

Fichier:

PDF, 721 KB

english, 1995

45

The presenilin-1 familial Alzheimer's disease mutation P117L decreases neuronal differentiation of embryonic murine neural progenitor cells

Lorenza Eder-Colli, Noelia Abad-Estarlich, Carine Pannetier, Philippe G. Vallet, Claude Walzer, Gregory A. Elder, Nikolaos K. Robakis, Constantin Bouras, Armand Savioz

Journal:

Brain Research Bulletin

Année:

2009

Langue:

english

Fichier:

PDF, 1.60 MB

english, 2009

46

A CBP Binding Transcriptional Repressor Produced by the PS1/ϵ-Cleavage of N-Cadherin Is Inhibited by PS1 FAD Mutations

Philippe Marambaud, Paul H Wen, Anindita Dutt, Junichi Shioi, Akihiko Takashima, Robert Siman, Nikolaos K Robakis

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 544 KB

english, 2003

47

The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice

Paul H. Wen, Patrick R. Hof, Xiaoping Chen, Karen Gluck, Gregory Austin, Steven G. Younkin, Linda H. Younkin, Rita DeGasperi, Miguel A. Gama Sosa, Nikolaos K. Robakis, Vahram Haroutunian, Gregory A. E

Journal:

Experimental Neurology

Année:

2004

Langue:

english

Fichier:

PDF, 763 KB

english, 2004

48

Mechanisms of AD neurodegeneration may be independent of Aβ and its derivatives

Nikolaos K. Robakis

Journal:

Neurobiology of Aging

Année:

2011

Langue:

english

Fichier:

PDF, 712 KB

english, 2011

49

Extracellular progranulin protects cortical neurons from toxic insults by activating survival signaling

Jindong Xu, Maria Xilouri, Julien Bruban, Junichi Shioi, Zhiping Shao, Ioannis Papazoglou, Kostas Vekrellis, Nikolaos K. Robakis

Journal:

Neurobiology of Aging

Année:

2011

Langue:

english

Fichier:

PDF, 1.90 MB

english, 2011

50

Chondroitin sulfate of appican, the proteoglycan form of amyloid precursor protein, produced by C6 glioma cells interacts with heparin-binding neuroregulatory factors

Yuko Umehara, Shuhei Yamada, Shuji Nishimura, Junichi Shioi, Nikolaos K. Robakis, Kazuyuki Sugahara

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 154 KB

english, 2004