Volume 1; Issue 8

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ChemMedChem
Volume 1; Issue 8

ChemMedChem

Volume 1; Issue 8

1

FlexNovo: Structure-Based Searching in Large Fragment Spaces

Jörg Degen, Matthias Rarey

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2006

2

Synthesis and Activity of Carbazole Derivatives Against Mycobacterium tuberculosis

Taylor A. Choi, Regina Czerwonka, Wolfgang Fröhner, Micha P. Krahl, Kethiri R. Reddy, Scott G. Franzblau, Hans-Joachim Knölker

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 95 KB

english, 2006

3

Permeability of Phospholipid Vesicles to the Tumor Antigen Epitope gp100280–288

Antonella Cavazza, Mario Marini, Giulio C. Spagnoli, Michel Adamina, L. Giorgio Roda

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 102 KB

english, 2006

4

Phosphopeptide Ligands of the SHP-1 N-SH2 Domain: Effects on Binding and Stimulation of Phosphatase Activity

Kornelia Hampel, Ina Kaufhold, Martin Zacharias, Frank D. Böhmer, Diana Imhof

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 424 KB

english, 2006

5

The Predicted 3D Structures of the Human M1 Muscarinic Acetylcholine Receptor with Agonist or Antagonist Bound

Joyce Yao-chun Peng, Nagarajan Vaidehi, Spencer E. Hall, William A. Goddard III

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2006

6

Improving Potency, Selectivity, and Water Solubility of Adenosine A1 Receptor Antagonists: Xanthines Modified at Position 3 and Related Pyrimido[1,2,3-cd]purinediones

Stefanie Weyler, Friederike Fülle, Martina Diekmann, Britta Schumacher, Sonja Hinz, Karl-Norbert Klotz, Christa E. Müller

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 214 KB

english, 2006

7

GR Ligands: Can We Improve the Established Drugs?

Hartmut Rehwinkel, Heike Schäcke

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 75 KB

english, 2006

8

Automated Protein–Ligand Crystallography for Structure-Based Drug Design

Wijnand T. M. Mooij, Michael J. Hartshorn, Ian J. Tickle, Andrew J. Sharff, Marcel L. Verdonk, Harren Jhoti

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2006

9

Integrated Approach Using Protein and Ligand Information to Analyze Selectivity- and Affinity-Determining Features of Carbonic Anhydrase Isozymes

Alexander Hillebrecht, Claudiu T. Supuran, Gerhard Klebe

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 818 KB

english, 2006

10

In Situ Polymerized Hydrogels for Repairing Scleral Incisions Used in Pars Plana Vitrectomy Procedures

Michel Wathier, M. Starck Johnson, Michael A. Carnahan, Claxton Baer, Brooks W. McCuen, Terry Kim, Mark W. Grinstaff

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 299 KB

english, 2006

11

Design, Synthesis, and In Vivo Efficacy of Glycine Transporter-1 (GlyT1) Inhibitors Derived from a Series of [4-Phenyl-1-(propylsulfonyl)piperidin-4-yl]methyl Benzamides

Craig W. Lindsley, Zhijian Zhao, William H. Leister, Julie O'Brien, Wei Lemaire, David L. Williams Jr., Tsing-Bau Chen, Raymond S. L. Chang, Maryann Burno, Marlene A. Jacobson, Cyrille Sur, Gene G. Ki

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 198 KB

english, 2006

12

Modern Biopharmaceuticals: Design, Development and Optimization. By Jörg Knäblein.

George Kauffmann

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 74 KB

english, 2006

13

The Adrenergic Receptors in the 21st Century. Edited by Dianne M. Perez.

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 31 KB

english, 2006

14

The 7 TM G-Protein-Coupled Receptor Target Family

Edgar Jacoby, Rochdi Bouhelal, Marc Gerspacher, Klaus Seuwen

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2006

15

Helicobacter Connections

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 990 KB

english, 2006

16

Cover Picture: Automated Protein–Ligand Crystallography for Structure-Based Drug Design (ChemMedChem 8/2006)

Wijnand T. M. Mooij, Michael J. Hartshorn, Ian J. Tickle, Andrew J. Sharff, Marcel L. Verdonk, Harren Jhoti

Journal:

Année:

2006

Fichier:

PDF, 33 KB

2006

17

Graphical Abstract: ChemMedChem 8/2006

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 664 KB

english, 2006

18

From our sister journals: ChemMedChem 8/2006

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 284 KB

english, 2006

19

Preview: ChemMedChem 8/2006

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 31 KB

english, 2006