Volume 15

Molecular Therapy

Volume 15

1

Sine-wave Current for Efficient and Safe In Vivo Gene Transfer

Liu, Feng, Sag, Demet, Wang, Jue, Shollenberger, Lisa M, Niu, Feilong, Yuan, Xing, Li, Shyh-Dar, Thompson, Mike, Monahan, Paul

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 301 KB

english, 2007

2

Current Status of Cardiovascular Gene Therapy

Rissanen, Tuomas T, Ylä-Herttuala, Seppo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 278 KB

english, 2007

3

Murine Retroviral but not Human Cellular Promoters Induce In Vivo Erythroid-specific Deregulation that can be Partially Prevented by Insulators

Ged, Cécile, de Verneuil, Hubert, Moreau-Gaudry, François, Robert-Richard, Elodie, Richard, Emmanuel, Malik, Punam

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 434 KB

english, 2007

4

Improved Human β-globin Expression from Self-inactivating Lentiviral Vectors Carrying the Chicken Hypersensitive Site-4 (cHS4) Insulator Element

Arumugam, Paritha I, Scholes, Jessica, Perelman, Natalya, Xia, Ping, Yee, Jiing-Kuan, Malik, Punam

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 553 KB

english, 2007

5

Rejection of Metastatic 4T1 Breast Cancer by Attenuation of Treg Cells in Combination With Immune Stimulation

Chen, Li, Huang, Tian-Gui, Meseck, Marcia, Mandeli, John, Fallon, John, Woo, Savio LC

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 333 KB

english, 2007

6

Gene Transfer to Ocular Stem Cells by Early Gestational Intraamniotic Injection of Lentiviral Vector

Endo, Masayuki, Zoltick, Philip W, Chung, Daniel C, Bennett, Jean, Radu, Antoneta, Muvarak, Nidal, Flake, Alan W

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 289 KB

english, 2007

7

Successful Immunization with a Single Injection of Non-integrating Lentiviral Vector

Negri, Donatella RM, Michelini, Zuleika, Baroncelli, Silvia, Spada, Massimo, Vendetti, Silvia, Buffa, Viviana, Bona, Roberta, Leone, Pasqualina, Klotman, Mary E, Cara, Andrea

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 337 KB

english, 2007

8

Stem and Progenitor Cells in Skeletal Muscle Development, Maintenance, and Therapy

Péault, Bruno, Rudnicki, Michael, Torrente, Yvan, Cossu, Giulio, Tremblay, Jacques P, Partridge, Terry, Gussoni, Emanuela, Kunkel, Louis M, Huard, Johnny

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 293 KB

english, 2007

9

Adhesion Receptors Mediate Efficient Non-viral Gene Delivery

Zuhorn, Inge S, Kalicharan, Dharamdajal, Robillard, George T, Hoekstra, Dick

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 553 KB

english, 2007

10

Striatal Delivery of Neurturin by CERE-120, an AAV2 Vector for the Treatment of Dopaminergic Neuron Degeneration in Parkinson's Disease

Gasmi, Mehdi, Herzog, Christopher D, Brandon, Eugene P, Cunningham, Justine J, Ramirez, G Anthony, Ketchum, Elias T, Bartus, Raymond T

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 216 KB

english, 2007

11

A Novel Dual-targeted Lentiviral Vector Leads to Specific Transduction of Prostate Cancer Bone Metastases In Vivo After Systemic Administration

Pariente, Nonia, Morizono, Kouki, Virk, Mandeep S, Petrigliano, Frank A, Reiter, Robert E, Lieberman, Jay R, Chen, Irvin SY

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 729 KB

english, 2007

12

The Genetic Engineering of Hematopoietic Stem Cells: the Rise of Lentiviral Vectors, the Conundrum of the LTR, and the Promise of Lineage-restricted Vectors

Chang, Alex H, Sadelain, Michel

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 214 KB

english, 2007

13

Targeted Inflammation During Oncolytic Virus Therapy Severely Compromises Tumor Blood Flow

Breitbach, Caroline J, Paterson, Jennifer M, Lemay, Chantal G, Falls, Theresa J, McGuire, Allison, Parato, Kelley A, Stojdl, David F, Daneshmand, Manijeh, Speth, Kelly, Kirn, David, McCart, J Andrea,

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 673 KB

english, 2007

14

Subcutaneous Peripheral Injection of Cationized Gelatin/DNA Polyplexes As a Platform for Non-viral Gene Transfer to Sensory Neurons

Thakor, Devang, Spigelman, Igor, Tabata, Yasuhiko, Nishimura, Ichiro

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 428 KB

english, 2007

15

The Influence of Blood on In Vivo Adenovirus Bio-distribution and Transduction

Baker, Andrew H, Mcvey, John H, Waddington, Simon N, Di Paolo, Nelson C, Shayakhmetov, Dmitry M

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 429 KB

english, 2007

16

Rapid Optimization of Gene Delivery by Parallel End-modification of Poly(β-amino ester)s

Zugates, Gregory T, Peng, Weidan, Zumbuehl, Andreas, Jhunjhunwala, Siddharth, Huang, Yu-Hung, Langer, Robert, Sawicki, Janet A, Anderson, Daniel G

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 468 KB

english, 2007

17

Bone Regeneration by Regulated In Vivo Gene Transfer Using Biocompatible Polyplex Nanomicelles

Itaka, Keiji, Ohba, Shinsuke, Miyata, Kanjiro, Kawaguchi, Hiroshi, Nakamura, Kozo, Takato, Tsuyoshi, Chung, Ung-Il, Kataoka, Kazunori

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 391 KB

english, 2007

18

Systemic Toxicity–Efficacy Profile of ICOVIR-5, a Potent and Selective Oncolytic Adenovirus Based on the pRB Pathway

Cascallo, Manel, Alonso, Marta M, Rojas, Juan J, Perez-Gimenez, Anna, Fueyo, Juan, Alemany, Ramon

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 411 KB

english, 2007

19

Transgenic Enrichment of Cardiomyocytes From Human Embryonic Stem Cells

Anderson, David, Self, Tim, Mellor, Ian R, Goh, Gareth, Hill, Stephen J, Denning, Chris

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 544 KB

english, 2007

20

A Novel Cell-penetrating Peptide, M918, for Efficient Delivery of Proteins and Peptide Nucleic Acids

El-Andaloussi, Samir, Johansson, Henrik J, Holm, Tina, Langel, Ülo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 468 KB

english, 2007

21

Viral Vector–mediated and Cell-based Therapies for Treatment of Cystic Fibrosis

Flotte, Terence R, Ng, Philip, Dylla, Doug E, McCray, Paul B, Wang, Guoshun, Kolls, Jay K, Hu, Jim

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 384 KB

english, 2007

22

Intracellular Trafficking of a Fiber-modified Adenovirus Using Lipid Raft/Caveolae Endocytosis

Rogée, Sophie, Grellier, Elodie, Bernard, Claudine, Loyens, Anne, Beauvillain, Jean-Claude, D'halluin, Jean-Claude, Colin, Morvane

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 804 KB

english, 2007

23

MicroRNAs in Disease and Potential Therapeutic Applications

Soifer, Harris S, Rossi, John J, Sætrom, Pål

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 229 KB

english, 2007

24

Antisense PNA Accumulates in Escherichia coli and Mediates a Long Post-antibiotic Effect

Nikravesh, Abbas, Dryselius, Rikard, Faridani, Omid R, Goh, Shan, Sadeghizadeh, Majid, Behmanesh, Mehrdad, Ganyu, Anita, Klok, Erik Jan, Zain, Rula, Good, Liam

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 382 KB

english, 2007

25

PiggyBac Transposon-mediated Gene Transfer in Human Cells

Wilson, Matthew H, Coates, Craig J, George, Alfred L

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 248 KB

english, 2007

26

Identification of Differentially Expressed Genes Involved in the Formation of Multicellular Tumor Spheroids by HT-29 Colon Carcinoma Cells

Dardousis, Kleomenis, Voolstra, Chris, Roengvoraphoj, Monic, Sekandarzad, Asieb, Mesghenna, Senait, Winkler, Johannes, Ko, Yon, Hescheler, Jürgen, Sachinidis, Agapios

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 390 KB

english, 2007

27

Biomaterials Approach to Expand and Direct Differentiation of Stem Cells

Chai, Chou, Leong, Kam W

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 225 KB

english, 2007

28

Bystander Killing of Malignant Glioma by Bone Marrow–derived Tumor-Infiltrating Progenitor Cells Expressing a Suicide Gene

Miletic, Hrvoje, Fischer, Yvonne, Litwak, Sara, Giroglou, Tsanan, Waerzeggers, Yannic, Winkeler, Alexandra, Li, Huongfeng, Himmelreich, Uwe, Lange, Claudia, Stenzel, Werner, Deckert, Martina, Neumann,

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 886 KB

english, 2007

29

Replication-competent Vectors and Empty Virus-like Particles: New Retroviral Vector Designs for Cancer Gene Therapy or Vaccines

Dalba, Charlotte, Bellier, Bertrand, Kasahara, Noriyuki, Klatzmann, David

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 248 KB

english, 2007

30

Intravenously Injected Human Fibroblasts Home to Skin Wounds, Deliver Type VII Collagen, and Promote Wound Healing

Woodley, David T, Remington, Jennifer, Huang, Yi, Hou, Yingping, Li, Wei, Keene, Douglas R, Chen, Mei

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 287 KB

english, 2007

31

Spinal Muscular Atrophy: SMN2 Pre-mRNA Splicing Corrected by a U7 snRNA Derivative Carrying a Splicing Enhancer Sequence

Marquis, Julien, Meyer, Kathrin, Angehrn, Larissa, Kämpfer, Sacha S, Rothen-Rutishauser, Barbara, Schümperli, Daniel

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 318 KB

english, 2007

32

Avian Influenza Virus Hemagglutinin Display on Baculovirus Envelope: Cytoplasmic Domain Affects Virus Properties and Vaccine Potential

Yang, Ding-Gang, Chung, Yao-Chi, Lai, Yiu-Kay, Lai, Chia-Wei, Liu, Hung-Jen, Hu, Yu-Chen

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 405 KB

english, 2007

33

Expression of Mutated Huntingtin Fragment in the Putamen Is Sufficient to Produce Abnormal Movement in Non-human Primates

Palfi, Stéphane, Brouillet, Emmanuel, Jarraya, Béchir, Bloch, Jocelyne, Jan, Caroline, Shin, Masahiro, Condé, Françoise, Li, Xiao-Jiang, Aebischer, Patrick, Hantraye, Philippe, Déglon, Nicole

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 467 KB

english, 2007

34

2′-O-methyl-modified RNAs Act as TLR7 Antagonists

Robbins, Marjorie, Judge, Adam, Liang, Lisa, McClintock, Kevin, Yaworski, Ed, MacLachlan, Ian

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 207 KB

english, 2007

35

Lentiviral Vectors with CMV or MHCII Promoters Administered In Vivo: Immune Reactivity Versus Persistence of Expression

Kimura, Takahiro, Koya, Richard C, Anselmi, Laura, Sternini, Catia, Wang, He-Jing, Comin-Anduix, Begonya, Prins, Robert M, Faure-Kumar, Emmanuelle, Rozengurt, Nora, Cui, Yan, Kasahara, Noriyuki, Strip

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 690 KB

english, 2007

36

Inhibition of Hepatitis C Virus Infection in Cell Culture by Small Interfering RNAs

Chevalier, Christophe, Saulnier, Aure, Benureau, Yann, Fléchet, Dorian, Delgrange, David, Colbère-Garapin, Florence, Wychowski, Czeslaw, Martin, Annette

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 736 KB

english, 2007

37

Hydrodynamic Gene Delivery: Its Principles and Applications

Suda, Takeshi, Liu, Dexi

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 215 KB

english, 2007

38

Dendritic Cell Function After Gene Transfer with Adenovirus-calcium Phosphate Co-precipitates

Seiler, Michael P, Gottschalk, Stephen, Cerullo, Vincenzo, Ratnayake, Maheshika, Mane, Viraj P, Clarke, Christian, Palmer, Donna J, Ng, Philip, Rooney, Cliona M, Lee, Brendan

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 159 KB

english, 2007

39

Safe Selection of Genetically Manipulated Human Primary Keratinocytes with Very High Growth Potential Using CD24

Bergoglio, Valérie, Larcher, Fernando, Chevallier-Lagente, Odile, Bernheim, Alain, Danos, Olivier, Sarasin, Alain, Rio, Marcela Del, Magnaldo, Thierry

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2007

40

Transduction of Brain by Herpes Simplex Virus Vectors

Berges, Bradford K, Wolfe, John H, Fraser, Nigel W

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 198 KB

english, 2007

41

Prolonged Remission of Diabetes by Regeneration of β Cells in Diabetic Mice Treated with Recombinant Adenoviral Vector Expressing Glucagon-like Peptide-1

Liu, Meng-Ju, Shin, Seungjin, Li, Na, Shigihara, Toshikatsu, Lee, Young-Sun, Yoon, Ji-Won, Jun, Hee-Sook

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 238 KB

english, 2007

42

Phenotypic Correction of α-Sarcoglycan Deficiency by Intra-arterial Injection of a Muscle-specific Serotype 1 rAAV Vector

Fougerousse, Francoise, Bartoli, Marc, Poupiot, Jérôme, Arandel, Ludovic, Durand, Muriel, Guerchet, Nicolas, Gicquel, Evelyne, Danos, Olivier, Richard, Isabelle

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 381 KB

english, 2007

43

Research Highlights

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 280 KB

english, 2007

44

Complete Correction of Enzymatic Deficiency and Neurochemistry in the GM1-gangliosidosis Mouse Brain by Neonatal Adeno-associated Virus–mediated Gene Delivery

Broekman, M L D, Baek, R C, Comer, L A, Fernandez, J L, Seyfried, T N, Sena-Esteves, M

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 389 KB

english, 2007

45

Control of Splicing Efficiency by the Mouse Histone H2a Element in a Murine Leukemia Virus–based Retroviral Vector

Lee, Jun-Tae, Yu, Seung Shin, Kim, V Narry, Kim, Sunyoung

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 223 KB

english, 2007

46

ASGT Advises NIH on Funding of Gene Therapy Trials

Williams, David A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 221 KB

english, 2007

47

Stem Cell Collection and Gene Transfer in Fanconi Anemia

Kelly, Patrick F, Radtke, Susan, Kalle, Christof von, Balcik, Brenden, Bohn, Kimberley, Mueller, Robin, Schuesler, Todd, Haren, Moira, Reeves, Lilith, Cancelas, Jose A, Leemhuis, Thomas, Harris, Richa

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 203 KB

english, 2007

48

Carrier Cell-based Delivery of an Oncolytic Virus Circumvents Antiviral Immunity

Power, Anthony T, Wang, Jiahu, Falls, Theresa J, Paterson, Jennifer M, Parato, Kelley A, Lichty, Brian D, Stojdl, David F, Forsyth, Peter A J, Atkins, Harry, Bell, John C

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 400 KB

english, 2007

49

Therapeutic Angiogenesis Inhibits or Rescues Chemotherapy-induced Peripheral Neuropathy: Taxol- and Thalidomide-induced Injury of Vasa Nervorum is Ameliorated by VEGF

Kirchmair, Rudolf, Tietz, Anne B, Panagiotou, Eleftheria, Walter, Dirk H, Silver, Marcy, Yoon, Young-Sup, Schratzberger, Peter, Weber, Alberto, Kusano, Kengo, Weinberg, David H, Ropper, Allan H, Isner

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 254 KB

english, 2007

50

AAV1 Mediated Co-expression of Formylglycine-Generating Enzyme and Arylsulfatase A Efficiently Corrects Sulfatide Storage in a Mouse Model of Metachromatic Leukodystrophy

Kurai, Toshiyuki, Hisayasu, Sanae, Kitagawa, Ryo, Migita, Makoto, Suzuki, Hidenori, Hirai, Yukihiko, Shimada, Takashi

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 250 KB

english, 2007

51

The Influence of Antisense Oligonucleotide Length on Dystrophin Exon Skipping

Harding, P L, Fall, A M, Honeyman, K, Fletcher, S, Wilton, S D

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 233 KB

english, 2007

52

Nectin-1 Expression by Squamous Cell Carcinoma is a Predictor of Herpes Oncolytic Sensitivity

Yu, Zhenkun, Adusumilli, Prasad S, Eisenberg, David P, Darr, Elizabeth, Ghossein, Ronald A, Li, Sen, Liu, Shiquan, Singh, Bhuvanesh, Shah, Jatin P, Fong, Yuman, Wong, Richard J

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 348 KB

english, 2007

53

Central Nervous System-directed AAV2/5-Mediated Gene Therapy Synergizes with Bone Marrow Transplantation in the Murine Model of Globoid-cell Leukodystrophy

Lin, Darshong, Donsante, Anthony, Macauley, Shannon, Levy, Beth, Vogler, Carole, Sands, Mark S

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 285 KB

english, 2007

54

In This Issue

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 201 KB

english, 2007

55

Somatic Integration From an Adenoviral Hybrid Vector into a Hot Spot in Mouse Liver Results in Persistent Transgene Expression Levels In Vivo

Ehrhardt, Anja, Yant, Stephen R, Giering, Jeffery C, Xu, Hui, Engler, Jeffrey A, Kay, Mark A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 525 KB

english, 2007

56

Integrating DNA Vectors For Gene Therapy

Hackett, Perry B

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 530 KB

english, 2007

57

Baculovirus-based Vaccination Vectors Allow for Efficient Induction of Immune Responses Against Plasmodium falciparum Circumsporozoite Protein

Strauss, Robert, Hüser, Andreas, Ni, Shaoheng, Tuve, Sebastian, Kiviat, Nancy, Sow, Papa Salif, Hofmann, Christian, Lieber, André

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 388 KB

english, 2007

58

Effective Suicide Gene Therapy for Leukemia in a Model of Insertional Oncogenesis in Mice

Blumenthal, Martina, Skelton, Dianne, Pepper, Karen A, Jahn, Thomas, Methangkool, Emily, Kohn, Donald B

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 287 KB

english, 2007

59

Development of a Conditionally Replicating Pseudorabies Virus for HER-2/neu-overexpressing Bladder Cancer Therapy

Shiau, Ai-Li, Lin, Yu-Ping, Shieh, Gia-Shing, Su, Chih-Hau, Wu, Wen-Luan, Tsai, Yuh-Shyan, Cheng, Chih-Wei, Lai, Ming-Derg, Wu, Chao-Liang

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 300 KB

english, 2007

60

Retroviral Insertion Mutagenesis in Mice as a Comparative Oncogenomics Tool to Identify Disease Genes in Human Leukemia

Touw, Ivo P, Erkeland, Stefan J

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 258 KB

english, 2007

61

Infected Cell Carriers: A New Strategy for Systemic Delivery of Oncolytic Measles Viruses in Cancer Virotherapy

Iankov, Ianko D, Blechacz, Boris, Liu, Chunsheng, Schmeckpeper, Jeffrey D, Tarara, James E, Federspiel, Mark J, Caplice, Noel, Russell, Stephen J

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 372 KB

english, 2007

62

Personalizing Oncolytic Virotherapy?

Kaur, Balveen, Chiocca, E Antonio

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 218 KB

english, 2007

63

Adenovirus-based Prime-boost Immunization for Rapid Vaccination Against Anthrax

McConnell, Michael J, Hanna, Philip C, Imperiale, Michael J

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 190 KB

english, 2007

64

Lentiviral Vector Transduction of a Dominant-negative Rev Gene Into Human CD34+ Hematopoietic Progenitor Cells Potently Inhibits Human Immunodeficiency Virus-1 Replication

Bahner, Ingrid, Sumiyoshi, Teiko, Kagoda, Mercy, Swartout, Robin, Peterson, Denise, Pepper, Karen, Dorey, Fred, Reiser, Jacob, Kohn, Donald B

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 213 KB

english, 2007

65

Cellular Dynamics of EGF Receptor–Targeted Synthetic Viruses

de Bruin, Karla, Ruthardt, Nadia, von Gersdorff, Katharina, Bausinger, Ralf, Wagner, Ernst, Ogris, Manfred, Bräuchle, Christoph

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 369 KB

english, 2007

66

Neuroprotection by Hsp104 and Hsp27 in Lentiviral-based Rat Models of Huntington's Disease

Perrin, Valérie, Régulier, Etienne, Abbas-Terki, Toufik, Hassig, Raymonde, Brouillet, Emmanuel, Aebischer, Patrick, Luthi-Carter, Ruth, Déglon, Nicole

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 649 KB

english, 2007

67

Potential Use of Gene Transfer in Athletic Performance Enhancement

Baoutina, Anna, Alexander, Ian E, Rasko, John EJ, Emslie, Kerry R

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 247 KB

english, 2007

68

Phase I Trial of Replication-competent Adenovirus-mediated Suicide Gene Therapy Combined with IMRT for Prostate Cancer

Freytag, Svend O, Movsas, Benjamin, Aref, Ibrahim, Stricker, Hans, Peabody, James, Pegg, Jan, Zhang, Yingshu, Barton, Kenneth N, Brown, Stephen L, Lu, Mei, Savera, Adnan, Kim, Jae Ho

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 214 KB

english, 2007

69

Pharmacological Enhancement of Mutated α-Glucosidase Activity in Fibroblasts from Patients with Pompe Disease

Parenti, Giancarlo, Zuppaldi, Alfredo, Gabriela Pittis, M, Rosaria Tuzzi, M, Annunziata, Ida, Meroni, Germana, Porto, Caterina, Donaudy, Francesca, Rossi, Barbara, Rossi, Massimiliano, Filocamo, Mirel

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 197 KB

english, 2007

70

Infectious Delivery and Expression of a 135 kb Human FRDA Genomic DNA Locus Complements Friedreich's Ataxia Deficiency in Human Cells

Gomez-Sebastian, Silvia, Gimenez-Cassina, Alfredo, Diaz-Nido, Javier, Lim, Filip, Wade-Martins, Richard

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 255 KB

english, 2007

71

A High Throughput In Vivo Model for Testing Delivery and Antiviral Effects of siRNAs in Vertebrates

Schyth, Brian Dall, Lorenzen, Niels, Pedersen, Finn Skou

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 470 KB

english, 2007

72

Stable Gene Transfer to Muscle Using Non-integrating Lentiviral Vectors

Apolonia, Luis, Waddington, Simon N, Fernandes, Carolina, Ward, Natalie J, Bouma, Gerben, Blundell, Michael P, Thrasher, Adrian J, Collins, Mary K, Philpott, Nicola J

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 291 KB

english, 2007

73

Lentiviral Vector–mediated Autonomous Differentiation of Mouse Bone Marrow Cells into Immunologically Potent Dendritic Cell Vaccines

Koya, Richard C, Kimura, Takahiro, Ribas, Antoni, Rozengurt, Nora, Lawson, Gregory W, Faure-Kumar, Emmanuelle, Wang, He-jing, Herschman, Harvey, Kasahara, Noriyuki, Stripecke, Renata

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 843 KB

english, 2007

74

Inhibitor of Heat-shock Protein 90 Enhances the Antitumor Effect of DNA Vaccine Targeting Clients of Heat-shock Protein

Lin, Chi-Chen, Tu, Cheng-Fen, Yen, Meng-Chi, Chen, Ming-Chuan, Hsieh, Wan-Jung, Chang, Wen-Chang, Chang, Wen-Tsang, Lai, Ming-Derg

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 296 KB

english, 2007

75

AAV Vectors, Insertional Mutagenesis, and Cancer

Russell, David W

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 501 KB

english, 2007

76

Long-term Engraftment of Single Genetically Modified Human Epidermal Holoclones Enables Safety Pre-assessment of Cutaneous Gene Therapy

Larcher, Fernando, Dellambra, Elena, Rico, Laura, Bondanza, Sergio, Murillas, Rodolfo, Cattoglio, Claudia, Mavilio, Fulvio, Jorcano, José L, Zambruno, Giovanna, Del Rio, Marcela

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 488 KB

english, 2007

77

Histone Modifications are Associated with the Persistence or Silencing of Vector-mediated Transgene Expression In Vivo

Riu, Efren, Chen, Zhi-Ying, Xu, Hui, He, Chen-Yi, Kay, Mark A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 288 KB

english, 2007

78

VEGF-specific Short Hairpin RNA–expressing Oncolytic Adenovirus Elicits Potent Inhibition of Angiogenesis and Tumor Growth

Yoo, Ji Young, Kim, Joo-Hang, Kwon, Young-Guen, Kim, Eok-Cheon, Kim, Nam Kyu, Choi, Hye Jin, Yun, Chae-Ok

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 325 KB

english, 2007

79

Engineering Artificial Antigen-presenting Cells to Express a Diverse Array of Co-stimulatory Molecules

Suhoski, Megan M, Golovina, Tatiana N, Aqui, Nicole A, Tai, Victoria C, Varela-Rohena, Angel, Milone, Michael C, Carroll, Richard G, Riley, James L, June, Carl H

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 935 KB

english, 2007

80

Comparison of Adenoviruses From Species B, C, E, and F After Intravenous Delivery

Stone, Daniel, Liu, Ying, Li, Zong-Yi, Tuve, Sebastian, Strauss, Robert, Lieber, André

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 530 KB

english, 2007

81

Genetic Manipulation of Skin Stem Cells: Success, Hope, and Challenges Ahead

Barrandon, Yann

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 218 KB

english, 2007

82

A Dual Role of EGFR Protein Tyrosine Kinase Signaling in Ubiquitination of AAV2 Capsids and Viral Second-strand DNA Synthesis

Zhong, Li, Zhao, Weihong, Wu, Jianqing, Li, Baozheng, Zolotukhin, Sergei, Govindasamy, Lakshmanan, Agbandje-McKenna, Mavis, Srivastava, Arun

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 441 KB

english, 2007

83

Human Matrix Metalloproteinase-8 Gene Delivery Increases the Oncolytic Activity of a Replicating Adenovirus

Cheng, Jin, Sauthoff, Harald, Huang, YaoQi, Kutler, David I, Bajwa, Sofia, Rom, William N, Hay, John G

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 788 KB

english, 2007

84

Safety and Immunogenicity of Tyrosinase DNA Vaccines in Patients with Melanoma

Wolchok, Jedd D, Yuan, Jianda, Houghton, Alan N, Gallardo, Humilidad F, Rasalan, Teresa S, Wang, Jian, Zhang, Yan, Ranganathan, Rajaram, Chapman, Paul B, Krown, Susan E, Livingston, Philip O, Heywood,

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 412 KB

english, 2007

85

Adenovirus Transduction is Required for the Correction of Diabetes Using Pdx-1 or Neurogenin-3 in the Liver

Wang, Alfred Y, Ehrhardt, Anja, Xu, Hui, Kay, Mark A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 286 KB

english, 2007

86

Enhanced Cellular Immune Responses Elicited by an Engineered HIV-1 Subtype B Consensus-based Envelope DNA Vaccine

Yan, Jian, Yoon, Hanna, Kumar, Sanjeev, Ramanathan, Mathura P, Corbitt, Natasha, Kutzler, Michele, Dai, Anlan, Boyer, Jean D, Weiner, David B

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 470 KB

english, 2007

87

Targeted Genome Modifications Using Integrase‐deficient Lentiviral Vectors

Cornu, Tatjana I, Cathomen, Toni

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 261 KB

english, 2007

88

Transplanted Hepatocytes Over-expressing FoxM1B Efficiently Repopulate Chronically Injured Mouse Liver Independent of Donor Age

Brezillon, Nicolas, Lambert-Blot, Martine, Morosan, Serban, Couton, Dominique, Mitchell, Claudia, Kremsdorf, Dina, Costa, Robert H, Gilgenkrantz, Helene, Guidotti, Jacques-Emmanuel

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 255 KB

english, 2007

89

Lentiviral-mediated Expression of Polysialic Acid in Spinal Cord and Conditioning Lesion Promote Regeneration of Sensory Axons Into Spinal Cord

Zhang, Yi, Zhang, Xinyu, Wu, Dongsheng, Verhaagen, Joost, Richardson, Peter M, Yeh, John, Bo, Xuenong

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2007

90

Inhibition of Tumor Growth and Metastasis Establishment by Adenovirus-mediated Gene Transfer Delivery of the Antiangiogenic Factor 16K hPRL

Nguyen, Ngoc-Quynh-Nhu, Cornet, Anne, Blacher, Silvia, Tabruyn, Sébastien P, Foidart, Jean-Michel, Noël, Agnès, Martial, Joseph A, Struman, Ingrid

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 444 KB

english, 2007

91

Messenger RNA as a Source of Transposase for Sleeping Beauty Transposon–mediated Correction of Hereditary Tyrosinemia Type I

Wilber, Andrew, Wangensteen, Kirk J, Chen, Yixin, Zhuo, Lijuan, Frandsen, Joel L, Bell, Jason B, Chen, Zongyu J, Ekker, Stephen C, McIvor, R Scott, Wang, Xin

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 787 KB

english, 2007

92

Comparison of D-G3139 and Its Enantiomer L-G3139 in Melanoma Cells Demonstrates Minimal In Vitro but Dramatic In Vivo Chiral Dependency

Lai, Johnathan C, Brown, Bob D, Voskresenskiy, Anatoliy M, Vonhoff, Stefan, Klussman, Sven, Tan, Wenzhi, Colombini, Marco, Weeratna, Risini, Miller, Paul, Benimetskaya, Luba, Stein, Cy A

Journal:

Molecular Therapy

Année:

2007

Fichier:

PDF, 313 KB

2007

93

Early STAT1 Activation After Systemic Delivery of HSV Amplicon Vectors Suppresses Transcription of The Vector-encoded Transgene

Suzuki, Masataka, Chiocca, E Antonio, Saeki, Yoshinaga

Journal:

Molecular Therapy

Année:

2007

Fichier:

PDF, 421 KB

2007

94

Biodistribution and Tumor Infectivity of Semliki Forest Virus Vectors in Mice: Effects of Re‐administration

Rodriguez-Madoz, Juan R, Prieto, Jesus, Smerdou, Cristian

Journal:

Molecular Therapy

Année:

2007

Fichier:

PDF, 490 KB

2007

95

mda-7 in Combination with Bevacizumab Treatment Produces a Synergistic and Complete Inhibitory Effect on Lung Tumor Xenograft

Inoue, Satoshi, Hartman, Amanda, Branch, Cynthia D, Bucana, Corazan D, Bekele, Benjamin N, Stephens, L Clifton, Chada, Sunil, Ramesh, Rajagopal

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 316 KB

english, 2007

96

Targeting Interferon-α Increases Antitumor Efficacy and Reduces Hepatotoxicity of E1A-mutated Spread-enhanced Oncolytic Adenovirus

Shashkova, Elena V, Spencer, Jacqueline F, Wold, William S M, Doronin, Konstantin

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 448 KB

english, 2007

97

Five-year Follow-up of Trial of Replication-competent Adenovirus-mediated Suicide Gene Therapy for Treatment of Prostate Cancer

Freytag, Svend O, Stricker, Hans, Peabody, James, Pegg, Jan, Paielli, Dell, Movsas, Benjamin, Barton, Kenneth N, Brown, Stephen L, Lu, Mei, Kim, Jae Ho

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 123 KB

english, 2007

98

Viral Clostridial Light Chain Gene-based Control of Penicillin-induced Neocortical Seizures

Yang, Jun, Teng, Qingshan, Federici, Thais, Najm, Imad, Chabardes, Stephan, Moffitt, Michael, Alexopoulos, Andreas, Riley, Jonathan, Boulis, Nicholas M

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 455 KB

english, 2007

99

Polyethylenimine-complexed Plasmid Particles Targeting Focal Adhesion Kinase Function as Melanoma Tumor Therapeutics

Li, Shufeng, Dong, Wei, Zong, Yiwei, Yin, Wu, Jin, Guanghui, Hu, Qingang, Huang, Xiaofeng, Jiang, Wenhui, Hua, Zi-Chun

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 419 KB

english, 2007

100

Multiple Reduced-intensity Conditioning Regimens Facilitate Correction of Fabry Mice After Transplantation of Transduced Cells

Liang, Sheng-Ben, Yoshimitsu, Makoto, Poeppl, Armando, Rasaiah, Vanessa I, Cai, Jianhui, Fowler, Daniel H, Medin, Jeffrey A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 206 KB

english, 2007

101

Antisense Oligonucleotide-induced Exon Skipping Across the Human Dystrophin Gene Transcript

Wilton, Steve D, Fall, Abbie M, Harding, Penny L, McClorey, Graham, Coleman, Catherine, Fletcher, Susan

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 165 KB

english, 2007

102

Role of Acid Ceramidase in Resistance to FasL: Therapeutic Approaches Based on Acid Ceramidase Inhibitors and FasL Gene Therapy

Elojeimy, Saeed, Liu, Xiang, Mckillop, John C, El-Zawahry, Ahmed M, Holman, David H, Cheng, Jonathan Y, Meacham, William D, Mahdy, Ayman EM, Saad, Antonio F, Turner, Lorianne S, Cheng, Joseph, A Day,

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 239 KB

english, 2007

103

The Suicide Gene Therapy Challenge: How to Improve a Successful Gene Therapy Approach

Bonini, Chiara, Bondanza, Attilio, Perna, Serena Kimi, Kaneko, Shin, Traversari, Catia, Ciceri, Fabio, Bordignon, Claudio

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 171 KB

english, 2007

104

Mesenchymal Stem Cell-mediated Gene Delivery of Bone Morphogenetic Protein-2 in an Articular Fracture Model

Zachos, Terri, Diggs, Alisha, Weisbrode, Steven, Bartlett, Jeffrey, Bertone, Alicia

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 752 KB

english, 2007

105

The RAS/Raf1/MEK/ERK Signaling Pathway Facilitates VSV-mediated Oncolysis: Implication for the Defective Interferon Response in Cancer Cells

Noser, Josh A, Mael, Amber A, Sakuma, Ryuta, Ohmine, Seiga, Marcato, Paola, WK Lee, Patrick, Ikeda, Yasuhiro

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 339 KB

english, 2007

106

American Society of Gene Therapy10th Annual MeetingMay 30–June 3, 2007Seattle, WA

Journal:

Molecular Therapy

Année:

2007

Fichier:

PDF, 2.87 MB

2007

107

Replication-competent Adenovirus-mediated Suicide Gene Therapy with Radiation in a Preclinical Model of Pancreatic Cancer

Freytag, Svend O, Barton, Kenneth N, Brown, Stephen L, Narra, Vinod, Zhang, Yingshu, Tyson, Don, Nall, Colleen, Lu, Mei, Ajlouni, Munther, Movsas, Benjamin, Kim, Jae Ho

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 515 KB

english, 2007

108

Monoclonal T-Cell Receptors: New Reagents for Cancer Therapy

Stauss, Hans J, Cesco-Gaspere, Michela, Thomas, Sharyn, Hart, Daniel P, Xue, Shao-An, Holler, Angelika, Wright, Graham, Perro, Mario, Little, Ann-Margaret, Pospori, Constantina, King, Judy, Morris, Em

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 360 KB

english, 2007

109

Toll-like Receptors Impact on Safety and Efficacy of Gene Transfer Vectors

Hensley, Scott E, Amalfitano, Andrea

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 177 KB

english, 2007

110

Chemotherapy Enhances CD8+ T Cell-mediated Antitumor Immunity Induced by Vaccination With Vaccinia Virus

Song, Chung Kil, Han, Hee Dong, Noh, Kyung Hee, Kang, Tae Heung, Park, Yong Sung, Kim, Jin Hee, Park, Eun Suk, Shin, Byung Cheol, Kim, Tae Woo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 256 KB

english, 2007

111

Androgen Receptor Attenuation of Ad5 Replication: Implications for the Development of Conditionally Replication Competent Adenoviruses

Höti, Naseruddin, Li, Ying, Chen, Chien-Lun, Chowdhury, Wasim H, Johns, David C, Xia, Qinghua, Kabul, Arup, Hsieh, Jer-Tsong, Berg, Michael, Ketner, Gary, Lupold, Shawn E, Rodriguez, Ronald

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 346 KB

english, 2007

112

Systemic Cancer Gene Therapy Using Adeno-associated Virus Type 1 Vector Expressing MDA-7/IL24

Tahara, Ichiro, Miyake, Koichi, Hanawa, Hideki, Kurai, Toshiyuki, Hirai, Yukihiko, Ishizaki, Masamichi, Uchida, Eiji, Tajiri, Takashi, Shimada, Takashi

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 379 KB

english, 2007

113

Time Course of Transgene Expression After Intrastriatal Pseudotyped rAAV2/1, rAAV2/2, rAAV2/5, and rAAV2/8 Transduction in the Rat

Reimsnider, Sharon, Manfredsson, Fredric P, Muzyczka, Nicholas, Mandel, Ronald J

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 690 KB

english, 2007

114

Integrating Ideas on Insertional Mutagenesis by Gene Transfer Vectors

Frederickson, Robert M

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 265 KB

english, 2007

115

A New Multi-clade DNA Prime/Recombinant MVA Boost Vaccine Induces Broad and High Levels of HIV-1-specific CD8+ T-cell and Humoral Responses in Mice

Bråve, Andreas, Boberg, Andreas, Gudmundsdotter, Lindvi, Rollman, Erik, Hallermalm, Kristian, Ljungberg, Karl, Blomberg, Pontus, Stout, Richard, Paulie, Staffan, Sandström, Eric, Biberfeld, Gunnel, Ea

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 419 KB

english, 2007

116

Transduction of Human Embryonic Stem Cells by Foamy Virus Vectors

Gharwan, Helen, Hirata, Roli K, Wang, Peirong, Richard, Robert E, Wang, Linlin, Olson, Erik, Allen, James, Ware, Carol B, Russell, David W

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 522 KB

english, 2007

117

Long-term Skeletal Muscle Protection After Gene Transfer in a Mouse Model of LGMD-2D

Pacak, Christina A, Walter, Glenn A, Gaidosh, Gabe, Bryant, Nathan, Lewis, Melissa A, Germain, Sean, Mah, Cathryn S, Campbell, Kevin P, Byrne, Barry J

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 688 KB

english, 2007

118

Timing of Therapeutic Intervention Determines Functional and Survival Outcomes in a Mouse Model of Late Infantile Batten Disease

Cabrera-Salazar, Mario A, Roskelley, Eric M, Bu, Jie, Hodges, Bradley L, Yew, Nelson, Dodge, James C, Shihabuddin, Lamya S, Sohar, Istvan, Sleat, David E, Scheule, Ronald K, Davidson, Beverly L, Cheng

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 546 KB

english, 2007

119

Peripheral Transgene Expression of Plasma Gelsolin Reduces Amyloid in Transgenic Mouse Models of Alzheimer's Disease

Hirko, Aaron C, Meyer, Edwin M, King, Michael A, Hughes, Jeffery A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 449 KB

english, 2007

120

Sca-1+ Hematopoietic Cell–based Gene Therapy with a Modified FGF-2 Increased Endosteal/Trabecular Bone Formation in Mice

Hall, Susan L, Lau, Kin-Hing William, Chen, Shin-Tai, Wergedal, Jon E, Srivastava, Apurva, Klamut, Henry, Sheng, Matilda H-C, Gridley, Daila S, Mohan, Subburaman, Baylink, David J

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 369 KB

english, 2007

121

Biological Differences in rAAV Transduction of Airway Epithelia in Humans and in Old World Non-human Primates

Liu, Xiaoming, Luo, Meihui, Trygg, Cyndi, Yan, Ziying, Lei-Butters, Diana CM, Smith, Carolina I, Fischer, Anne C, Munson, Keith, Guggino, William B, Bunnell, Bruce A, Engelhardt, John F

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 636 KB

english, 2007

122

Humility and Clinical Trials

Associate Editor, James

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 183 KB

english, 2007

123

Immunization by Application of DNA Vaccine onto a Skin Area Wherein the Hair Follicles Have Been Induced into Anagen-onset Stage

Shaker, Dalia S, Sloat, Brian R, Le, Uyen M, Löhr, Christiane V, Yanasarn, Nijaporn, Fischer, Kay A, Cui, Zhengrong

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 352 KB

english, 2007

124

Inhibition of Enterovirus 71 in Virus-infected Mice by RNA Interference

Tan, Eng Lee, Tan, Theresa May Chin, Chow, Vincent Tak Kwong, Poh, Chit Laa

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 517 KB

english, 2007

125

Autologous Transplantation of SM/C-2.6+ Satellite Cells Transduced with Micro-dystrophin CS1 cDNA by Lentiviral Vector into mdx Mice

Ikemoto, Madoka, Fukada, So-ichiro, Uezumi, Akiyoshi, Masuda, Satoru, Miyoshi, Hiroyuki, Yamamoto, Hiroshi, Wada, Michiko R, Masubuchi, Nami, Miyagoe-Suzuki, Yuko, Takeda, Shin'ichi

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 666 KB

english, 2007

126

One-year Expression From High-capacity Adenoviral Vectors in the Brains of Animals With Pre-existing Anti-adenoviral Immunity: Clinical Implications

Barcia, Carlos, Jimenez-Dalmaroni, Maximiliano, Kroeger, Kurt M, Puntel, Mariana, Rapaport, Alison J, Larocque, Daniel, King, Gwendalyn D, Johnson, Stephen A, Liu, Chunyan, Xiong, Weidong, Candolfi, M

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 619 KB

english, 2007

127

Adenoviruses 16 and CV23 Efficiently Transduce Human Low-passage Brain Tumor and Cancer Stem Cells

Skog, Johan, Edlund, Karin, Bergenheim, A Tommy, Wadell, Göran

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 318 KB

english, 2007

128

A Dual-Targeted Lentiviral Vector Homing in on Prostate Bone Metastases

Hu, Yufang, Stout, David, Wu, Lily

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 309 KB

english, 2007

129

Targeting the Untargetable: Oncolytic Virotherapy for the Cancer Stem Cell

Liu, Ta-Chiang, Kirn, David

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 156 KB

english, 2007

130

An International Conversation on Stem Cell Gene Therapy

Williams, David A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 213 KB

english, 2007

131

Adeno-associated Virus Type 5 Reduces Learning Deficits and Restores Glutamate Receptor Subunit Levels in MPS VII Mice CNS

Liu, Gumei, Chen, Yong Hong, He, Xiaohua, Martins, Inês, Heth, Jason A, Chiorini, John A, Davidson, Beverly L

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 224 KB

english, 2007

132

Retroviral Vectors Encoding a Reverse Transcription-activated Transgene Efficiently Limit Expression of the Gene to Target Cells

Burke, John Douglas, Morris, John C

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 269 KB

english, 2007

133

Correction of the Biochemical and Functional Deficits in Fabry Mice Following AAV8–mediated Hepatic Expression of α-galactosidase A

Ziegler, Robin J, Cherry, Maribeth, Barbon, Christine M, Li, Chester, Bercury, Scott D, Armentano, Donna, Desnick, Robert J, Cheng, Seng H

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 343 KB

english, 2007

134

Specific Inhibition of HBV Replication In Vitro and In Vivo With Expressed Long Hairpin RNA

Weinberg, Marc S, Ely, Abdullah, Barichievy, Samantha, Crowther, Carol, Mufamadi, Steven, Carmona, Sergio, Arbuthnot, Patrick

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 295 KB

english, 2007

135

A Peptide Fusion a Day Keeps the Aggregates Away

Prochiantz, Alain

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 226 KB

english, 2007

136

Armed Interference: Oncolytic Viruses Engineered to Carry Antitumor shRNAs

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 226 KB

english, 2007

137

Comparison of HIV-derived Lentiviral and MLV-based Gammaretroviral Vector Integration Sites in Primate Repopulating Cells

Beard, Brian C, Dickerson, David, Beebe, Kate, Gooch, Christina, Fletcher, James, Okbinoglu, Tulin, Miller, Daniel G, Jacobs, Michael A, Kaul, Rajinder, Kiem, Hans-Peter, Trobridge, Grant D

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 301 KB

english, 2007

138

Improved Retinal Transduction In Vivo and Photoreceptor-specific Transgene Expression Using Adenovirus Vectors With Modified Penton Base

Cashman, Siobhan M, McCullough, Laura, Kumar-Singh, Rajendra

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 601 KB

english, 2007

139

Non-invasive Imaging in Gene Therapy

Kristian Räty, Jani, Liimatainen, Timo, Unelma Kaikkonen, Minna, Gröhn, Olli, Jumani Airenne, Kari, Ylä-Herttuala, Seppo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 411 KB

english, 2007

140

Uncoating Reo: Uncovering the Steps Critical for Oncolysis

Lemay, Guy, Tumilasci, Vanessa, Hiscott, John

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 181 KB

english, 2007

141

Functional Analysis of Various Promoters in Lentiviral Vectors at Different Stages of In Vitro Differentiation of Mouse Embryonic Stem Cells

Hong, Sunghoi, Hwang, Dong-Youn, Yoon, Soonsang, Isacson, Ole, Ramezani, Ali, Hawley, Robert G, Kim, Kwang-Soo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 701 KB

english, 2007

142

A Study of the Role of Nell-1 Gene Modified Goat Bone Marrow Stromal Cells in Promoting New Bone Formation

Aghaloo, Tara, Jiang, Xinquan, Soo, Chia, Zhang, Zhiyuan, Zhang, Xiuli, Hu, Jingzhou, Pan, Hongya, Hsu, Tiffany, Wu, Benjamin, Ting, Kang, Zhang, Xinli

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2007

143

Comparison of D-G3139 and Its Enantiomer L-G3139 in Melanoma Cells Demonstrates Minimal In Vitro but Dramatic In Vivo Chiral Dependency

Lai, Johnathan C, Brown, Bob D, Voskresenskiy, Anatoliy M, Vonhoff, Stefan, Klussman, Sven, Tan, Wenzhi, Colombini, Marco, Weeratna, Risini, Miller, Paul, Benimetskaya, Luba, Stein, Cy A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 313 KB

english, 2007

144

Early STAT1 Activation After Systemic Delivery of HSV Amplicon Vectors Suppresses Transcription of The Vector-encoded Transgene

Suzuki, Masataka, Chiocca, E Antonio, Saeki, Yoshinaga

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 421 KB

english, 2007

145

Biodistribution and Tumor Infectivity of Semliki Forest Virus Vectors in Mice: Effects of Re‐administration

Rodriguez-Madoz, Juan R, Prieto, Jesus, Smerdou, Cristian

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 490 KB

english, 2007

146

A Two-hybrid Screen Identifies Cathepsins B and L as Uncoating Factors for Adeno-associated Virus 2 and 8

Akache, Bassel, Grimm, Dirk, Shen, Xuan, Fuess, Sally, Yant, Stephen R, Glazer, Dariya S, Park, Julie, Kay, Mark A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 255 KB

english, 2007

147

RNAi Gets Vote of Confidence from Big Pharma

Frederickson, Robert M

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 216 KB

english, 2007

148

Foxp3-expressing CD4+T Cells Under the Control of IFN-γ Promoter Prevent Diabetes in NOD Mice

Wang, Renxi, Han, Gencheng, Wang, Jianan, Song, Lun, Chen, Guojiang, Xu, Ruonan, Yu, Ming, Qian, Jiahua, Shen, Beifen, Li, Yan

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 339 KB

english, 2007

149

Decorin Gene Transfer Promotes Muscle Cell Differentiation and Muscle Regeneration

Li, Yong, Li, Juan, Zhu, Jinghong, Sun, Bin, Branca, Maria, Tang, Ying, Foster, William, Xiao, Xiao, Huard, Johnny

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 798 KB

english, 2007

150

A New Serious Adverse Event in a Gene Therapy Study

Friedmann, Theodore

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 189 KB

english, 2007

151

Engineered Human tmpk/AZT As a Novel Enzyme/Prodrug Axis for Suicide Gene Therapy

Sato, Takeya, Neschadim, Anton, Konrad, Manfred, Fowler, Daniel H, Lavie, Arnon, Medin, Jeffrey A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 222 KB

english, 2007

152

Macrophage-mediated Bystander Effect Triggered by Tumor Cell Apoptosis

Huang, Yinghui, Lee, Casey, Borgström, Per, Gjerset, Ruth A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 402 KB

english, 2007

153

Gene Therapy and Biosecurity

Imperiale, Michael J

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 219 KB

english, 2007

154

In Vivo Study of HIV-1 Tat Arginine-rich Motif Unveils Its Transport Properties

Cardarelli, Francesco, Serresi, Michela, Bizzarri, Ranieri, Giacca, Mauro, Beltram, Fabio

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 623 KB

english, 2007

155

Recombinant Human Foamy Virus, a Novel Vector for Neurological Disorders Gene Therapy, Drives Production of GAD in Cultured Astrocytes

Liu, Wanhong, Liu, Zhongchun, Cao, Xiongbin, Cao, Zhijian, Xue, Lu, Zhu, Fan, He, Xiaohua, Li, Wenxin

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 555 KB

english, 2007

156

Stable Ethics: Enrolling Non-Treatment-Refractory Volunteers in Novel Gene Transfer Trials

Kimmelman, Jonathan

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 226 KB

english, 2007

157

Oncolytic HSV and Erlotinib Inhibit Tumor Growth and Angiogenesis in a Novel Malignant Peripheral Nerve Sheath Tumor Xenograft Model

Mahller, Yonatan Y, Vaikunth, Sachin S, Currier, Mark A, Miller, Shyra J, Ripberger, Maria C, Hsu, Ya-Hsuan, Mehrian-Shai, Ruty, Collins, Margaret H, Crombleholme, Timothy M, Ratner, Nancy, Cripe, Tim

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 331 KB

english, 2007

158

Development of Renal-targeted Vectors Through Combined In Vivo Phage Display and Capsid Engineering of Adenoviral Fibers From Serotype 19p

Denby, Laura, Work, Lorraine M, Seggern, Dan J Von, Wu, Eugene, McVey, John H, Nicklin, Stuart A, Baker, Andrew H

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 585 KB

english, 2007

159

Activation of CFTR-specific T Cells in Cystic Fibrosis Mice Following Gene Transfer

Limberis, Maria P, Figueredo, Joanita, Calcedo, Roberto, Wilson, James M

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 424 KB

english, 2007

160

Successful Compensation for Dystrophin Deficiency by a Helper-dependent Adenovirus Expressing Full-length Utrophin

Deol, Jatinderpal R, Danialou, Gawiyou, Larochelle, Nancy, Bourget, Mylène, Moon, Joon-Shik, Liu, An-Bang, Gilbert, Rénald, Petrof, Basil J, Nalbantoglu, Josephine, Karpati, George

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 449 KB

english, 2007

161

What Are the Consequences of the Fourth Case?

Associate Editor, Christopher

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 170 KB

english, 2007

162

Prevention of Irradiation-induced Salivary Hypofunction by Microvessel Protection in Mouse Salivary Glands

Cotrim, Ana P, Sowers, Anastasia, Mitchell, James B, Baum, Bruce J

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 262 KB

english, 2007

163

Gene Therapy Prolongs PSA Doubling Time in Prostate Cancer Patients

Thompson, Timothy C, Rodriguez, Ron

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 217 KB

english, 2007

164

Myostatin Blockade: A New Way to Enhance Skeletal Muscle Repair in Old Age?

Yablonka-Reuveni, Zipora

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 187 KB

english, 2007

165

Antagonism of Myostatin Enhances Muscle Regeneration During Sarcopenia

Siriett, Victoria, Salerno, Mônica Senna, Berry, Carole, Nicholas, Gina, Bower, Rob, Kambadur, Ravi, Sharma, Mridula

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 436 KB

english, 2007

166

RAC Reviews Serious Adverse Event Associated with AAV Therapy Trial

Williams, David A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 214 KB

english, 2007

167

Stable Transgene Expression in Mice Generated from Retrovirally Transduced Embryonic Stem Cells

Hamanaka, Sanae, Nabekura, Tsukasa, Otsu, Makoto, Yoshida, Hisahiro, Nagata, Michio, Usui, Joichi, Takahashi, Satoru, Nagasawa, Toshiro, Nakauchi, Hiromitsu, Onodera, Masafumi

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 259 KB

english, 2007

168

Immune Responses to AAV Capsid: Are Mice Not Humans After All?

Herzog, Roland W

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 570 KB

english, 2007

169

Adenovirus Toxicity and Tropism In Vivo: Not as Simple as A,B,C (or D,E,F)

Baker, Andrew H

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 158 KB

english, 2007

170

I Could Die for You: New Prospects for Suicide in Gene Therapy

Baum, Christopher

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 218 KB

english, 2007

171

Long-term Correction of β-Thalassemia With Minimal Cellular Requirement and Transplantation Modalities

Felfly, Hady, Trudel, Marie

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 565 KB

english, 2007

172

Characteristics of Lentiviral Vectors Harboring the Proximal Promoter of the vav Proto-oncogene: A Weak and Efficient Promoter for Gene Therapy

Almarza, Elena, Río, Paula, Meza, Nestor W, Aldea, Montserrat, Agirre, Xabier, Guenechea, Guillermo, Segovia, José C, Bueren, Juan A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 574 KB

english, 2007

173

Genetic Selection of Cardiomyocytes from Human Embryonic Stem Cells

Mummery, Christine

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 206 KB

english, 2007

174

Evidence for Intercellular Trafficking of VP22 in Living Cells

Lemken, Marie-Luise, Wolf, Claudia, Wybranietz, Wolfgang A, Schmidt, Ulrike, Smirnow, Irina, Bühring, Hans-Joerg, Mack, Andreas F, Lauer, Ulrich M, Bitzer, Michael

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 382 KB

english, 2007

175

EGF Receptor Activation Decreases Retroviral Gene Transfer through Protein Kinase C-δ

Singh, Raghvendra, Andreadis, Stelios T

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 177 KB

english, 2007

176

Proteolytic Disassembly Is a Critical Determinant for Reovirus Oncolysis

Alain, Tommy, Kim, Tom SY, Lun, XueQing, Liacini, Adelhamid, Schiff, Leslie A, Senger, Donna L, Forsyth, Peter A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 756 KB

english, 2007

177

Toxicity of Fiber- and Penton Base–modified Adenovirus Type 5 Vectors on Lung Development in Newborn Rats

Waszak, Paul, Franqueville, Laure, Franco-Motoya, Marie-Laure, Rosa-Calatrava, Manuel, Boucherat, Olivier, Lindholm, Leif, Delacourt, Christophe, Boulanger, Pierre

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 733 KB

english, 2007

178

Modifying the Proliferative State of Target Cells to Control DNA Expression and Identifying Cell Types Transfected In Vivo

Riddle, Kathryn W, Kong, Hyun-Joon, Leach, J Kent, Fischbach, Claudia, Cheung, Charles, Anseth, Kristi S, Mooney, David J

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 246 KB

english, 2007

179

Lentiviral Gene Delivery of vMIP-II to Transplanted Endothelial Cells and Endothelial Progenitors Is Proangiogenic In Vivo

Cherqui, Stephanie, Kingdon, Kenneth M, Thorpe, Camille, Kurian, Sunil M, Salomon, Daniel R

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 583 KB

english, 2007

180

Tissue-specific Aberrations of Gene Expression in HPRT-deficient Mice: Functional Complexity in a Monogenic Disease?

Song, Shaochun, Friedmann, Theodore

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 855 KB

english, 2007

181

Neuronal Specificity of HSV/Sleeping Beauty Amplicon Transduction In Utero Is Driven Primarily by Tropism and Cell Type Composition

Peterson, Elise B, Mastrangelo, Michael A, Federoff, Howard J, Bowers, William J

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 961 KB

english, 2007

182

Correction of Murine Hemophilia A and Immunological Differences of Factor VIII Variants Delivered by Helper-dependent Adenoviral Vectors

Cerullo, Vincenzo, Seiler, Michael P, Mane, Viraj, Cela, Racel, Clarke, Christian, Kaufman, Randal J, Pipe, Steven W, Lee, Brendan

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 459 KB

english, 2007

183

Enhanced Survival of the LINCL Mouse Following CLN2 Gene Transfer Using the rh.10 Rhesus Macaque-derived Adeno-associated Virus Vector

Sondhi, Dolan, Hackett, Neil R, Peterson, Daniel A, Stratton, Jamie, Baad, Michael, Travis, Kelly M, Wilson, James M, Crystal, Ronald G

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 377 KB

english, 2007

184

Restoration of SMN Function: Delivery of a Trans-splicing RNA Re-directs SMN2 Pre-mRNA Splicing

Coady, Tristan H, Shababi, Monir, Tullis, Gregory E, Lorson, Christian L

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 334 KB

english, 2007

185

Engineering Oncolytic Measles Virus to Circumvent the Intracellular Innate Immune Response

Haralambieva, Iana, Iankov, Ianko, Hasegawa, Kosei, Harvey, Mary, Russell, Stephen J, Peng, Kah-Whye

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 357 KB

english, 2007

186

Urokinase Gene Transfer Augments Angiogenesis in Ischemic Skeletal and Myocardial Muscle

Traktuev, Dmitry O, Tsokolaeva, Zoya I, Shevelev, Alexander A, Talitskiy, Konstantin A, Stepanova, Victoria V, Johnstone, Brian H, Rahmat‐Zade, Tahmina M, Kapustin, Alexander N, Tkachuk, Vsevolod A, M

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 492 KB

english, 2007

187

Protein Transduction Domain-mediated Delivery of QBP1 Suppresses Polyglutamine-induced Neurodegeneration In Vivo

Popiel, H Akiko, Nagai, Yoshitaka, Fujikake, Nobuhiro, Toda, Tatsushi

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 155 KB

english, 2007

188

Correction of Clinical Manifestations of Canine Mucopolysaccharidosis I with Neonatal Retroviral Vector Gene Therapy

Traas, Anne M, Wang, Ping, Ma, Xiucui, Tittiger, Mindy, Schaller, Laura, O'donnell, Patricia, Sleeper, Meg M, Vite, Charles, Herati, Ramin, Aguirre, Gustavo D, Haskins, Mark, Ponder, Katherine P

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 969 KB

english, 2007

189

The Enhancing Effects of the Light Chain on Heavy Chain Secretion in Split Delivery of Factor VIII Gene

Chen, Lingxia, Zhu, Fuxiang, Li, Juan, Lu, Hui, Jiang, Haiyan, Sarkar, Rita, Arruda, Valder R, Wang, Jinhui, Zhao, Jennifer, Pierce, Glenn F, Ding, Qiulan, Wang, Xuefeng, Wang, Hongli, Pipe, Steven W,

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 195 KB

english, 2007

190

Morpholino Oligomer–Mediated Exon Skipping Averts the Onset of Dystrophic Pathology in the mdx Mouse

Fletcher, Sue, Honeyman, Kaite, Fall, Abbie M, Harding, Penny L, Johnsen, Russell D, Steinhaus, Joshua P, Moulton, Hong M, Iversen, Patrick L, Wilton, Stephen D

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 576 KB

english, 2007

191

Autologous Transplantation of Muscle Precursor Cells Modified with a Lentivirus for Muscular Dystrophy: Human Cells and Primate Models

Quenneville, Simon P, Chapdelaine, Pierre, Skuk, Daniel, Paradis, Matin, Goulet, Marlyne, Rousseau, Joël, Xiao, Xiao, Garcia, Luis, Tremblay, Jacques P

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 286 KB

english, 2007

192

A CD46-binding Chimpanzee Adenovirus Vector as a Vaccine Carrier

Tatsis, Nia, Blejer, Ariella, Lasaro, Marcio O, Hensley, Scott E, Cun, Ann, Tesema, Lello, Li, Yan, Gao, Guang-Ping, Xiang, Zhi Q, Zhou, Dongming, Wilson, James M, Ertl, Hildegund C J

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 216 KB

english, 2007

193

Mesenchymal Stem Cells Over-expressing Hepatocyte Growth Factor Improve Small-for-size Liver Grafts Regeneration

Yu, Yue, Yao, Ai-Hua, Chen, Nian, Pu, Li-Yong, Fan, Ye, Lv, Ling, Sun, Bei-Cheng, Li, Guo-Qiang, Wang, Xue-Hao

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 639 KB

english, 2007

194

DNAzyme-mediated Inhibition of Japanese Encephalitis Virus Replication in Mouse Brain

Appaiahgari, Mohan Babu, Vrati, Sudhanshu

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 418 KB

english, 2007

195

Characterization of the Relationship of AAV Capsid Domain Swapping to Liver Transduction Efficiency

Shen, Xuan, Storm, Terry, Kay, Mark A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 396 KB

english, 2007

196

Targeted Gene Transfer to Fetal Rat Lung Interstitium by Ultrasound-guided Intrapulmonary Injection

Henriques-Coelho, Tiago, Gonzaga, Sílvia, Endo, Masayuki, Zoltick, Philip W, Davey, Marcus, Leite-Moreira, Adelino F, Correia-Pinto, Jorge, Flake, Alan W

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 293 KB

english, 2007

197

Are Lentivirus Vectors Safer?

Williams, David A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 137 KB

english, 2007

198

Remodeling the NGVL Program to Meet Contemporary Needs

Hayward, Anthony R

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 184 KB

english, 2007

199

IL-6-Encoding Tumor Antigen Generates Potent Cancer Immunotherapy Through Antigen Processing and Anti-apoptotic Pathways

Hsieh, Chang-Yao, Chen, Chi-An, Huang, Chia-Yen, Chang, Ming-Cheng, Lee, Chien-Nan, Su, Yi-Ning, Cheng, Wen-Fang

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 343 KB

english, 2007

200

Correction in Female PKU Mice by Repeated Administration of mPAH cDNA Using phiBT1 Integration System

Chen, Li, Woo, Savio LC

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2007

201

Intranuclear Trafficking of Episomal DNA Is Transcription-dependent

Gasiorowski, Joshua Z, Dean, David A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 583 KB

english, 2007

202

An Immunocompetent Murine Model for Oncolysis with an Armed and Targeted Measles Virus

Ungerechts, Guy, Springfeld, Christoph, Frenzke, Marie E, Lampe, Johanna, Parker, William B, Sorscher, Eric J, Cattaneo, Roberto

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 324 KB

english, 2007

203

Increased Sensitivity of Radiated Murine Cervical Cancer Tumors to E7 Subunit Vaccine–driven CTL-mediated Killing Induces Synergistic Anti-tumor Activity

Ye, Gi Won, Park, Jae-Bok, Park, Young-Ja, Choi, Youn Seok, Sin, Jeong-Im

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 422 KB

english, 2007

204

Ras Transformation Mediates Reovirus Oncolysis by Enhancing Virus Uncoating, Particle Infectivity, and Apoptosis-dependent Release

Marcato, Paola, Shmulevitz, Maya, Pan, Da, Stoltz, Don, Lee, Patrick WK

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 649 KB

english, 2007

205

Persistent Expression of hF.IX After Tolerance Induction by In Utero or Neonatal Administration of AAV-1-F.IX in Hemophilia B Mice

Sabatino, Denise E, MacKenzie, Tippi C, Peranteau, William, Edmonson, Shyrie, Campagnoli, Cesare, Liu, Yi-Lin, Flake, Alan W, High, Katherine A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 355 KB

english, 2007

206

Modulation of Adenoviral Transduction In Vitro and In Vivo by Hyaluronan and its Receptor CD44

Chaudhuri, Saumya R, Mallam, Joshua N, Chévez-Barrios, Patricia, Wadhwa, Lalita, Ng, Philip, Hurwitz, Mary Y, Hurwitz, Richard L

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 178 KB

english, 2007

207

Enhancement of Gene Transfer to Human Myeloid Cells by Adenovirus–Fiber Complexes

Nepomuceno, Ronald R, Pache, Lars, Nemerow, Glen R

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 254 KB

english, 2007

208

Shedding Light on Tumor Targeting by Adenovirus

Associate Editor, Andrew H

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 222 KB

english, 2007

209

Treatment of Inflamed Pancreas with Enkephalin Encoding HSV-1 Recombinant Vector Reduces Inflammatory Damage and Behavioral Sequelae

Lu, Ying, McNearney, Terry A, Lin, Weidong, Wilson, Steven P, Yeomans, David C, Westlund, Karin N

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2007

210

A Decade of Accomplishments: Gene Therapy and the ASGT

Friedmann, Theodore

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 489 KB

english, 2007

211

Interactions Between Human Plasma Components and A Xenogenic Adenovirus Vector: Reduced Immunogenicity During Gene Transfer

Perreau, Matthieu, Guérin, Marie-Christine, Drouet, Christian, Kremer, Eric J

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 226 KB

english, 2007

212

Long-term Suppression of Experimental Arthritis Following Intramuscular Administration of a Pseudotyped AAV2/1-TNFR:Fc Vector

Sandalon, Ziv, Bruckheimer, Elizabeth M, Lustig, Kurt H, Burstein, Haim

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 189 KB

english, 2007

213

Development and Validation of a Robust and Versatile One-plasmid Regulated Gene Expression System

Szymanski, Paul, Kretschmer, Peter J, Bauzon, Maxine, Jin, Fang, Qian, Hu Sheng, Rubanyi, Gabor M, Harkins, Richard N, Hermiston, Terry W

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 291 KB

english, 2007

214

NIH Decides Against Continuing NGVLs in Their Current Form

Editor-in-Chief, David A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 117 KB

english, 2007

215

The Role of Immunosuppression in Gene- and Cell-Based Treatments for Duchenne Muscular Dystrophy

Arruda, Valder R

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 224 KB

english, 2007

216

Physiological Correction of Pompe Disease by Systemic Delivery of Adeno-associated Virus Serotype 1 Vectors

Mah, Cathryn, Pacak, Christina A, Cresawn, Kerry O, DeRuisseau, Lara R, Germain, Sean, Lewis, Melissa A, Cloutier, Denise A, Fuller, David D, Byrne, Barry J

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 241 KB

english, 2007

217

Type I Interferon Inhibits Antibody Responses Induced by a Chimpanzee Adenovirus Vector

Hensley, Scott E, Cun, Ann S, Giles-Davis, Wynetta, Li, Yan, Xiang, Zhiquan, Lasaro, Marcio O, Williams, Bryan R G, Silverman, Robert H, Ertl, Hildegund C J

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 269 KB

english, 2007

218

Design of Tissue-specific Regulatory Cassettes for High-level rAAV-mediated Expression in Skeletal and Cardiac Muscle

Salva, Maja Z, Himeda, Charis L, Tai, Phillip WL, Nishiuchi, Eiko, Gregorevic, Paul, Allen, James M, Finn, Eric E, Nguyen, Quynh G, Blankinship, Michael J, Meuse, Leonard, Chamberlain, Jeffrey S, Haus

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 519 KB

english, 2007

219

Toll-like Receptor 9 Triggers an Innate Immune Response to Helper-dependent Adenoviral Vectors

Cerullo, Vincenzo, Seiler, Michael P, Mane, Viraj, Brunetti-Pierri, Nicola, Clarke, Christian, Bertin, Terry K, Rodgers, John R, Lee, Brendan

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 253 KB

english, 2007

220

Lentiviral Vectors for T-cell Suicide Gene Therapy: Preservation of T-cell Effector Function After Cytokine-mediated Transduction

Qasim, Waseem, Mackey, Taylor, Sinclair, Jo, Chatziandreou, Ilenia, Kinnon, Christine, Thrasher, Adrian J, Gaspar, H Bobby

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 182 KB

english, 2007

221

Hydrodynamic Limb Vein Delivery of a Xenogeneic DNA Cancer Vaccine Effectively Induces Antitumor Immunity

Neal, Zane C, Bates, Mary K, Albertini, Mark R, Herweijer, Hans

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 253 KB

english, 2007

222

On the Role of CD4+ T Cells in the CD8+ T-Cell Response Elicited by Recombinant Adenovirus Vaccines

Yang, Teng Chih, Millar, James, Groves, Timothy, Zhou, Wenzhong, Grinshtein, Natalie, Parsons, Robin, Evelegh, Carole, Xing, Zhou, Wan, Yonghong, Bramson, Jonathan

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 456 KB

english, 2007

223

Programming the Next Generation of Dendritic Cells

Carroll, Richard G, June, Carl H

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 417 KB

english, 2007

224

Correction of DNA Protein Kinase Deficiency by Spliceosome-mediated RNA Trans-splicing and Sleeping Beauty Transposon Delivery

Zayed, Hatem, Xia, Lily, Yerich, Anton, Yant, Stephen R, Kay, Mark A, Puttaraju, M, McGarrity, Gerard J, Wiest, David L, McIvor, R Scott, Tolar, Jakub, Blazar, Bruce R

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 454 KB

english, 2007

225

Lentiviral Vectors Mediate Stable and Efficient Gene Delivery into Primary Murine Natural Killer Cells

Tran, Jimmy, Kung, Sam KP

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 544 KB

english, 2007

226

Efficacy of Helper-dependent Adenovirus Vector-mediated Gene Therapy in Murine Glycogen Storage Disease Type Ia

Koeberl, Dwight D, Sun, B, Bird, A, Chen, YT, Oka, K, Chan, L

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 318 KB

english, 2007

227

Vegf or EphA2 Antisense Polyamide-nucleic acids; Vascular Localization and Suppression of Retinal Neovascularization

Shen, Jikui, Xie, Bing, Hatara, Christina M, Hackett, Sean F, Campochiaro, Peter A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 738 KB

english, 2007

228

New Insights and Unresolved Issues Regarding Insertional Mutagenesis in X-linked SCID Gene Therapy

Pike-Overzet, Karin, van der Burg, Mirjam, Wagemaker, Gerard, van Dongen, Jacques JM, Staal, Frank JT

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 319 KB

english, 2007

229

Oncolytic Adenoviruses Kill Breast Cancer Initiating CD44+CD24–/Low Cells

Eriksson, Minna, Guse, Kilian, Bauerschmitz, Gerd, Virkkunen, Pekka, Tarkkanen, Maija, Tanner, Minna, Hakkarainen, Tanja, Kanerva, Anna, Desmond, Renee A, Pesonen, Sari, Hemminki, Akseli

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 274 KB

english, 2007

230

Umbilical Cord Blood–derived Progenitor Cells Enhance Muscle Regeneration in Mouse Hindlimb Ischemia Model

Koponen, Jonna K, Kekarainen, Tuija, E Heinonen, Suvi, Laitinen, Anita, Nystedt, Johanna, Laine, Jarmo, Ylä-Herttuala, Seppo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 462 KB

english, 2007

231

Research Highlights

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 343 KB

english, 2007

232

Apoptin Studies Illuminate Intersection Between Lipidomics and Tumor Suppressors

Chada, Sunil, Ramesh, Rajagopal

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 343 KB

english, 2007

233

Gene Transfer of An Engineered Zinc Finger Protein Enhances the Anti-angiogenic Defense System

Yokoi, Katsutoshi, Zhang, Huanda Steve, Kachi, Shu, Balaggan, Kamaljit S, Yu, Qi, Guschin, Dmitry, Kunis, Mike, Surosky, Richard, Africa, Liza M, Bainbridge, James W, Spratt, Sharon Kaye, Gregory, Phi

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 372 KB

english, 2007

234

2. AAV Vectors Do Not Increase the Risk of Tumor Formation in p53 Deficient Models

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 640 KB

english, 2007

235

3. Loss of Newly Formed Double-Stranded Genomes Is the Primary Cause of rAAV Low Transduction Efficacy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

236

4. AAV Labeling of Break-Prone Palindromes in Mammalian Genomes: Exploitation of the In Vivo rAAV Biology for Studies of Genomic Instability in Living Animals

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 636 KB

english, 2007

237

5. Site-Specific Integration of AAV2/2 and AAV2/8 Vectors in Hepatocytes In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

238

6. The Mre11/Rad50/Nbs1 Complex Restricts rAAV Transduction by Limiting Single-Stranded to Double-Stranded DNA Genome Conversion

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 592 KB

english, 2007

239

7. Slow Entry Process Results in Adeno-Associated Virus Sensitivity to Antibody Mediated Neutralization

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 591 KB

english, 2007

240

9. Adenovirus Vector Induced Immune Responses Are Dependent upon Multi-Faceted Interactions with Proteins of Both the Alternative and Classical Complement Pathways In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 564 KB

english, 2007

241

10. Fully Detargeted Polyethylene Glycol-Stealthed Adenovirus Vectors Demonstrate High Potency for Genetic Vaccination and Are Able To Escape from Pre-Existing Anti-Ad Humoral Immunity

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 563 KB

english, 2007

242

11. Characterization of Immune Responses Provoked by Alternative Adenovirus Serotypes Spanning Groups A-E

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 563 KB

english, 2007

243

12. Adenovirus Membrane-Lytic Activity Is Required for Kupffer Cell Toxicity and Contributes to the Innate Cytokine Response

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 602 KB

english, 2007

244

14. Adenovirus pIX Gene Is Co-Expressed with Transgene Expression and May Induce Host Immune Responses in First-Generation Adenovirus Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

245

15. Engineering a Recombinant Adenovirus for Targeted Transduction of Neutrophils for Use as Anti-Inflammatory Cell Vehicles

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 649 KB

english, 2007

246

16. Modification of Ad5 Hexon Hypervariable Regions Circumvents Pre-Existing Ad5 Neutralizing Antibodies

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2007

247

17. GnRH-Expressing Plasmid Delivered by Constant-Current Electroporation Can Regulate the Reproductive Axis in Horses

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 497 KB

english, 2007

248

18. Non-Viral Cutaneous Gene Transfer DNA Using In Vivo Electroporation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 344 KB

english, 2007

249

19. Optimised Pulses for Electro Gene Transfer to Muscle Tissue Reduce Adverse Effects on Cellular Integrity and Function

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 625 KB

english, 2007

250

20. Optimization of Definity Microbubble Concentrations and Acoustic Pressure Increases Ultrasound-Mediated Gene Transfer Efficiency While Reduces Tissue Damage

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 625 KB

english, 2007

251

21. Copolymer Protected BMP-2 Gene Vectors Immobilized in Poly(D,L-Lactide) Films on Titanium Implants Mediate Bone Regeneration in a Rat Mandibular Critical Bone Defect Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

252

22. Development of Computer-Controlled Injection Device for Hydrodynamic Gene Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 607 KB

english, 2007

253

23. Efficient Delivery and Long-Term Expression of a 135 kb LDLR Genomic DNA Locus In Vivo Following Hydrodynamic Tail Vein Injection

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 607 KB

english, 2007

254

24. Comparative Gene Expression In Vivo after Hydrodynamic Delivery and Polyethyleneimine-Conjugated Delivery of DNA Using the Sleeping Beauty Transposon System

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 534 KB

english, 2007

255

25. The Role of Alpha-Synuclein (α-syn) Phosphorylation at Ser-129 on the Development of Parkinson-Like Neurodegeneration

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 534 KB

english, 2007

256

27. Analysis of the Transduction and Biodistribution Patterns of Alternative AAV Vector Serotypes in the CNS of Adult Rhesus Macaques

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 604 KB

english, 2007

257

29. Genetic Engineering of Neural Stem Cells Specifies Motor Neuron and Oligodendrocyte Differentiation in the Adult Spinal Cord

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 644 KB

english, 2007

258

31. AAV Mediated Gene Transfer of IGF-1 and VEGF to the Ventricular System Provides Significant Therapeutic Benefit in a Mouse Model of Amyotrophic Lateral Sclerosis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 610 KB

english, 2007

259

32. HSV-Mediated Delivery of a TrkA-Repressing Engineered Zinc Finger Protein Transcription Factor Reduces Nociception in a Mouse Model of Bone Cancer Pain

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 610 KB

english, 2007

260

33. CD40-Targeted Adenoviral Vector Transduction of Dendritic Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

261

34. Intratumoral Manipulation of Dendritic Cells Elicits Immunological Memory in a Recurrent, Syngeneic Glioma Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 631 KB

english, 2007

262

35. Connective Tissue Growth Factor Encoding Tumor Antigen Generates Potent Antigen-Specific Cancer Immunotherapy through Prolonging Life-Span of Antigen-Presenting Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 631 KB

english, 2007

263

36. Combination of Tumor-Site Located CTLA-4 Blockade and Systemic Regulatory T Cell Depletion Induces Anti-Tumor Immunity

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

264

37. In Vivo Targeting of Tumor Antigens to DCs by Administration of Transduced Lymphocytes Results in Robust and Prolonged Immunization

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 637 KB

english, 2007

265

38. Co-Expression of Cytokine and Suicide Genes To Enhance the Activity and Safety of Tumor Specific Cytotoxic T Lymphocytes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

266

40. Generating Cytotoxic T Lymphocytes Against Prostate Specific Membrane Antigen by AAV-Loaded Dendritic Cells for the Treatment of Prostate Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 614 KB

english, 2007

267

41. Human Neural Progenitor Cells Homing to Glioma Xenografts

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 624 KB

english, 2007

268

42. Drug-Virus Interaction: Effect of Administration of Recombinant Adenoviruses on the Pharmacokinetics of Docetaxel in a Rat Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 624 KB

english, 2007

269

43. Nanoparticle-Delivery of Diphtheria Toxin DNA Inhibits Ovarian Tumor Growth

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

270

45. Prognostic Determinants Associated with Efficacy of Adenoviral p53 Gene Therapy (Advexin) in Patients with Recurrent Squamous Cell Carcinoma of the Head and Neck (SCCHN)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 591 KB

english, 2007

271

46. Adenoviral-Mediated Gene Transfer of Single Chain Fv 425:sTRAIL Fusion Protein Induces Target Cell Restricted Apoptosis in EGFR-Positive Tumor Cells and a Potent Bystander Effect without Toxicity In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

272

48. Increased Potency of Engineered FasL-Expressing T Cells Is Modified in Primary Prostate Cancer Cells by Common Chemotherapeutic Agents

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

273

50. Phase I Clinical Trial Study Ultilizing Oncolytic Adenovirus with HSP Gene Expression (H103) in Treating Patients with Advanced Solid Tumor

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 644 KB

english, 2007

274

52. Targeting Tissue Tropism of Coxsackievirus A21, an Oncolytic Enterovirus

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 611 KB

english, 2007

275

53. Human MSC for Delivery of Infectivity Enhanced Oncolytic Adenoviruses into Orthotopic Lung and Breast Tumors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

276

54. Mechanisms of Resistance of Primary Ovarian Cancer Cells to Viral Oncolysis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 603 KB

english, 2007

277

55. Design of ICP0 Deficient HSV Oncolytic Vectors for Treatment of Glioblastoma

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 603 KB

english, 2007

278

56. Prostate Restricted Replicative Adenovirus Expressing Human Endostatin-Angiostatin Fusion Gene Exhibiting Dramatic Antitumor Efficacy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 623 KB

english, 2007

279

57. Viral Delivery of shRNAs as a Potential Therapy for Huntington's Disease

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 623 KB

english, 2007

280

58. Optimization of Zinc Finger Nucleases for Gene Targeting in Mammalian Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 623 KB

english, 2007

281

59. Improved Toxicity Profile of Pol II- over Pol Ill-Promoted Hairpin RNAs Due to Reduced Expression Levels

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 635 KB

english, 2007

282

60. Transfer of siRNA Molecules Via Gap Junctions in Heart Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 635 KB

english, 2007

283

61. Supplementation with hRad51/54 or Antibodies Against Ku70/86 Increase the Efficiency of Single Stranded DNA-Mediated Genome Alteration in Preimplantation Stage Mouse Embryos

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

284

63. Antisense Oligonucleotide Induced Exon Skipping as a Therapy for Duchenne Muscular Dystrophy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 597 KB

english, 2007

285

64. SFHR Gene Targeting Strategy Optimization: Useful Tools and Increased Efficiency of Repair

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 601 KB

english, 2007

286

65. Karyotypic Changes May Be Inevitable in Retroviral Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 601 KB

english, 2007

287

66. Comparison of HIV-Derived Lentiviral and MLV-Based Gammaretroviral Vector Integration Sites in Primate Repopulating Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

288

68. Improving the Safety of HIV-1 Derived Gene Therapy Vectors: Reducing the Rate of SIN Repair and Polyadenylation Signal Readthrough

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 613 KB

english, 2007

289

69. Site-Specific Genomic Integration of Lentiviral DNA Circles

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

290

70. Assessing Gammaretroviral Vector Integration Preferences for DNase Hypersensitive Sites

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

291

71. Determination of the Profile and Site Preference of Lentiviral Vector Integration In Vivo and in Primary Astrocyte Cultures

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

292

72. Retroviral Integration Sites in Mucopolysaccharidosis VII Dogs

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

293

73. Identification of Genetic Insulator Elements for Safe Gene Therapy Viral Integrating Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 599 KB

english, 2007

294

74. Making Retroviral Gene Therapy Safer: Prevention of Retrovirus-Mediated Activation of Cellular Genes near the Integration Site by Engineering of the LTR

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 599 KB

english, 2007

295

76. In Vivo Selection of Targeted Gene Transfer Vectors from AAV Random Peptide Display Libraries

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 633 KB

english, 2007

296

78. Site Specific Modification of AAV Vector Particles with Biophysical Probes and Targeting Ligands Using Biotin Ligase

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

297

80. Directed Evolution of Adeno-Associated Viral Vectors with Novel Cellular Gene Delivery Properties

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

298

83. Acceleration and Augmentation of AAV-Mediated Gene Expression

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

299

84. High Titer Adeno-Associated Viral Vector Production by a Vero-Derived Producer Cell Line

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 573 KB

english, 2007

300

85. Insect Cell Production System: Alternative Startcodon Use for Improved AAV Infectivity

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 573 KB

english, 2007

301

86. Generation of More Infectious Type 1 AAV Vectors in Insect Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

302

87. Development and Characterization of a Relative Potency Assay for rAAV1 Vectors for Use as Vaccines

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 632 KB

english, 2007

303

88. Equal In Vivo Efficacy of Recombinant AAV1 Vector Produced in Either Mammalian or Insect Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 632 KB

english, 2007

304

89. Process Strategies for High Yield Production of Adeno-Associated Viruses in Insect Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

305

90. Scalable Method for Purification of Recombinant Adeno-Associated Viral Vector (rAAV) Type 6

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 638 KB

english, 2007

306

91. Weak Anion Exchange Column Chromatography Enhances the Resolution of Separation of AAV Empty Capsid and Full Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 638 KB

english, 2007

307

92. Affinity Chromatography Purification of rAAV Vectors Produced by Transfection or rHSV Co-Infection Using CaptureSelect® AAV Ligand

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

308

93. Long-Term CNS and Somatic Correction in MPS II Mice after Intrathecal Delivery of AAV 9 Vector

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 586 KB

english, 2007

309

94. Systemic Administration of AAV9-SUMF1 Gene Results in Re-Activation of Sulfatases in a Mouse Model of Multiple Sulfatase Deficiency (MSD)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 586 KB

english, 2007

310

95. Targeting of Refractory Sites in Mucopolysaccharidosis Type I Using a Nonviral Transferrin-α-L-Iduronidase Fusion Gene Product

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

311

96. Insulin-Like Growth Factor-1 Rescues Galactocerebrosidase-Mediated Toxicity in Hematopoietic Stem Cells: Relevance for Gene Therapy of Globoid Cell Leukodystrophy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 623 KB

english, 2007

312

99. Effects of LDL Receptor Gene Transfer on Tissue Cholesterol Levels in LDL Receptor Deficient Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 573 KB

english, 2007

313

100. Detection of CFTR Activity in Individual Epithelial Cells Following Adenovirus-Mediated Delivery of a cDNA Encoding Yellow Fluorescent Protein

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 626 KB

english, 2007

314

101. Long-Term Correction of Hyperphenylalanainemia in a Mouse Model of Phenylketonuria by Intramuscular Delivery rAAV Pseudotyped with Serotypes 8 or 1

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 626 KB

english, 2007

315

102. Down-Regulation of Hepatic Stearoyl CoA Desaturasel Prevents Diet-Induced Obesity in Rats

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

316

103. Low Doses of Self Complimentary Adeno-Associated Virus Vectors Pseudotyped with Nonhuman Primate Serotypes 8 and rh.10 Mediate Highly Efficient Transduction of the Liver

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

317

104. AAV-Mediated Gene Transfer to Muscle and Liver of MPS VI Animal Models

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

318

105. Lentivirus-Mediated Gimap5 Gene Delivery To Treat Diabetic BB Rats

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

319

107. Considerations for AAV8-Mediated Gene Therapy of Pompe Disease

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

320

108. Long-Term Efficacy of a Self-Complementary Adeno-Associated Virus Vector for Phenylketonuria Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 581 KB

english, 2007

321

109. Sleeping Beauty Transposon-Mediated Long-Term α-L-lduronidase Expression and Correction of Lysosomal Pathology in NOD/SCID Mice with MPS I

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 581 KB

english, 2007

322

110. Recombinant Adeno-Associated Virus Mediated Acyl coA Dehydrogenase (ACD) Gene Replacement in ACD-Deficient Mouse Models

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 587 KB

english, 2007

323

111. AAV1 Mediated Gene Therapy of Neonatal Fabry Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 586 KB

english, 2007

324

112. Novel Strategies To Inhibit Ocular Neovascularization Based on Sonic Hedgehog Pathway Blockade

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

325

113. Transduction of the Vasculature Using rAAV6

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 616 KB

english, 2007

326

114. AAV-Mediated Delivery of Paraoxonase 1 (PON1) to the ApoE-/- Mouse as Gene Therapy for Atherosclerosis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 616 KB

english, 2007

327

115. Adeno-Associated Virus 2-Based Gene Delivery of the Angiotensin II Type 2 Receptor Reduces Atherosclerosis and Associated Markers in LDLR Knockout Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

328

116. Gene Transfer in Mice Established That Residues Leu261, Trp264 and Phe265 Account for Apolipoprotein E-Induced Dyslipidemia and Affect the Formation of apoE Containing High Density Lipoprotein

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 617 KB

english, 2007

329

117. Balanced Co-Expression of VEGF164 and PDGF-BB Prevents Aberrant Angiogenesis and Improves Hindlimb Ischemia

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 617 KB

english, 2007

330

118. A Genetically Modified AAV Vector Shows Promise in Ex Vivo Treatment of Human Saphenous Vein

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

331

119. NOS2 Gene Transfer with a Synthetic Vector Inhibits Neointimal Hyperplasia in a Rabbit Vein Graft Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 627 KB

english, 2007

332

121. A Pressured-Freeze Method To Make Multi-Functional Echogenic Liposomes for Image-Guided and Ultrasound-Controlled Oligonucleotide Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 552 KB

english, 2007

333

122. AAV2 Pseudotyped with AAV9 Capsid Is an Efficient Vector for Vascular Gene Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2007

334

123. Intravascular Delivery of Plasmid DNA/Anti-DNA Antibody Complex Immobilized on Coronary Stent

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 604 KB

english, 2007

335

124. Transcriptional Targeting of Gene Expression to the Endothelium Using the Roundabout-4 Receptor Promoter

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 604 KB

english, 2007

336

125. Measurement of Flow-Mediated and Nitric Oxide Synthase-Dependent Vasodilation in Living Rats Using High Resolution Ultrasound

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 601 KB

english, 2007

337

126. Dp116 Expression in Dystrophin/Utrophin Double Knockout (mdx:utrir−/−) Mice Restores Muscle Mass and Viability but Does Not Correct Dystrophic Pathology

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 601 KB

english, 2007

338

127. Functional Capacity of Dystrophins N-Terminal Actin Binding Sequences

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 601 KB

english, 2007

339

128. Screening of Antisense Oligonucleotides for Human Dystrophin Exon Skipping in a GFP Reporter Culture System with High Sensitivity and Specificity

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

340

129. A Myoblast Expansion System for Improving the Efficiency of Autologous Stem Cell Therapy To Treat Muscular Dystrophy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 645 KB

english, 2007

341

131. In Utero Delivery of Adeno-Associated Virus Vector-Encoding Human Mini-Dystrophin Leads to Functional Correction in Dystrophin Deficient Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

342

134. Functional Analysis of alpha-Dystrobrevin-3 in Striated Muscle with rAAV6 Gene Transfer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

343

135. rAAV Type 8-Mediated Extensive Therapeutic Gene Delivery into Skeltal Muscle of α-Sarcoglycan Deficient Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 629 KB

english, 2007

344

136. Viral Based Therapeutic for LGMD Type 2D Deficiencies Demonstrates Long-Term Results in Alpha-Sarcoglycan Deficient Animals

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 629 KB

english, 2007

345

138. Ameliorating Dystrophic Pathology Via AAV-Mediated Gene Delivery of Myostatin Propeptide

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 619 KB

english, 2007

346

139. Isolation, Characterization, and Myogenesis of Satellite Cells Derived from Skeletal Muscle

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 619 KB

english, 2007

347

140. Gait in BioTO-2 and Bio14.6 Dystrophic Hamsters

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

348

142. Spliceosome-Mediated RNA Trans-Splicing for Muscular Dystrophies

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 601 KB

english, 2007

349

143. Effect of Insulin-Like Growth Factor-1 (IGF-1) on Global Gene Expression Profiles in Murine Skeletal Muscle

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2007

350

144. Safety Studies of the Hydrodynamic Limb Vein Delivery Procedure in Primates

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 586 KB

english, 2007

351

145. Vaxfectin™ -Formulated Plasmid DNA Measles Vaccine Elicits Protective Immune Response in Non-Human Primates

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 586 KB

english, 2007

352

146. DNA Vaccination in Combination with Constant-Current Electroporation Leads to an Increased Immune Response in Mice, Rabbits and Nonhuman Primates

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2007

353

147. Novel Strategy for Generation of Mucosal Immune Responses Against HIV-1 Following Systemic Vaccination

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 587 KB

english, 2007

354

148. Multivalent Adenovector-Based Malaria Vaccine Induces High Levels of Functional Antibodies

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 587 KB

english, 2007

355

149. Nasal Delivery of Adenovirus-Based Vaccine Bypasses Pre-Existing Immunity to the Vaccine Carrier and Improves the Quality of the Immune Response

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 611 KB

english, 2007

356

150. Vector Prime-Protein Boost Vaccine for Avian and Human Influenza Viruses

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 611 KB

english, 2007

357

151. Novel Genetic Vaccine for Anthrax Based on Recombinant AAV Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

358

153. Adenovector-Based Malaria Vaccine Induces Strong T-Cell and Antibody Responses Against Multiple Pre-Erythrocytic-Stage Antigens

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 645 KB

english, 2007

359

154. Severe Acute Respiratory Syndrome Coronavirus-Like Particles (SARS-CoVLPs) Stimulate Human Monocyte-Derived Dendritic Cell Activity and Induce Antibody Response in Mouse Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 612 KB

english, 2007

360

156. Protective Immune Responses Against Porcine Circovirus Type 2 Infection Generated by a Recombinant Modified Vaccinia Virus Expressing the Viral ORF Antigens as Vaccines

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 612 KB

english, 2007

361

157. Enhancement of Antibody and Cellurar Responses to Malaria DNA Vaccines by In Vivo Electroporation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

362

158. Adenovirus-Mediated Delivery of a Y. pestis V Antigen Variant with Reduced Immunomodulatory Properties Elicits Comparable Serum Anti-V Antigen IgG Titers to Adenovirus-Mediated Delivery of Wild-Type V Antigen

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 624 KB

english, 2007

363

159. Recombinant Adeno-Associated Virus Vectors Effectively Immunize Rabbits Via Intramuscular and Intranasal Routes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 624 KB

english, 2007

364

160. In Vivo Immunogenic Responses by Tuberculosis Vaccination with Sendai-Virosomal pDNA Encoding Mycobacterial Antigen 85 Complex A (mAg85A)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

365

161. In Vivo Electroporation Promotes Intra-Muscular DNA Uptake, Protein Expression, and Inflammation at the Site of Injection, Which Greatly Enhances the Immunogenicity of Hepatitis C Virus Non-Structural 3/4A DNA

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

366

163. Adenoviral Vector Prime-Protein Boost Vaccine for Melanoma

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 609 KB

english, 2007

367

164. Enhanced Anti-Tumor Effect of Modified Vaccinia Virus Expressing Human-gp100 Antigen and Rantes in Cancer Vaccine Approach

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 601 KB

english, 2007

368

165. Heat Shock Protein 70-Antigen Fusion Protein Expressing DNA Vaccine for Cancer Immunotherapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 601 KB

english, 2007

369

167. Macrophages Transduced with an Adenoviral Vector Expressing Glipr1 Suppress Tumor Growth and Metastasis in a Preclinical Metastatic Prostate Cancer Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

370

168. Allograft Vaccine for Epithelial Cancers

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 655 KB

english, 2007

371

170. Treatment of Metastatic Renal Cell Cancer Using Multiple IV Administrations of IL-12 Plasmid Nanopolyplexes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 646 KB

english, 2007

372

171. Preclinical Evaluation of an iCD40-Dendritic Cell Vaccine for Prostate Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 646 KB

english, 2007

373

172. Long Term Follow up of GVAX in NSCLC (MCCRC Results)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

374

173. Her-2/neu DNA Immunization through Constant-Current Electroporation Provides Long-Term Protection from Autochthonous Mammary Carcinomas

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 615 KB

english, 2007

375

174. B Cells Can Function as Tumor Antigen Presenting Cells In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 615 KB

english, 2007

376

176. Necrotic Tumor Cell Extracts Stimulate TLR2-Dependent T Cell Mediated Tumor Regression

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 546 KB

english, 2007

377

177. In Vivo Phagocytic Activity of Antigen Presenting Cells Infiltrating Intracranial Glioblastomas in Rats Treated with Adenoviruses Expressing TK and Flt3L

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 546 KB

english, 2007

378

178. Spontaneous Glioblastoma in Dogs: Preclinical Model for High Capacity Adenoviral Vector-Mediated Experimental Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 592 KB

english, 2007

379

179. A Phase I Clinical Trial of Liposome-Mediated Interferon-beta Gene Therapy for High-Grade Gliomas

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 592 KB

english, 2007

380

181. Eradication of Multifocal Glioma in a Syngeneic Glioblastoma Multiforme with Ad-Flt3L and Ad-HSV1-TK

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 609 KB

english, 2007

381

183. Interferon-alpha Gene Transfer Enhances Antitumor Activity of Allogeneic Hematopoietic Stem Cell Transplantation Against Solid Cancers

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

382

184. Induction of Efficient Antitumor Immunity to Murine Neuroblastoma Using Dendritic Cells Highly Activated by Temperature-Sensitive Mutant SeV/dF: A Preclinical Efficacy Study

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 646 KB

english, 2007

383

185. Development of Immunotherapeutics for Mantle Cell Lymphoma

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

384

186. A Phase I Study of Antitumor Vaccination Using Lung Cancer Cells Genetically-Modified To Express Alpha(1,3)galactosyltransferase (αGT) in Patients with Stage IV, Refractory or Recurrent Non-Small Cell Lung Cancer (NSCLC)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 593 KB

english, 2007

385

187. Adenovirus Expressing Interleukin 6 Increases the Anti-Tumor Activity of Dendritic Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 592 KB

english, 2007

386

188. Phase II Study of Intratumoral (IT) OncoVexGM-CSF, an Immune-Enhanced Oncolytic Herpes Simplex-1 Virus (HSV-1), in Patients with Stage IIIc/IV Malignant Melanoma (MM): A Preliminary Report of a Complete Response of Target and Reporter Lesions

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

387

189. Antitumoral Efficacy of Semliki Forest Virus Vectors Expressing IL-12 in Liver Tumor Models

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 603 KB

english, 2007

388

190. Induction and Enhancement of Cancer Immunity by Ion Particle Beam and Dendritic Cell Treatment of Murine Squamous Cell Carcinoma

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 603 KB

english, 2007

389

191. TGF-Beta Inhibition Augments Immuno-Gene Cytokine and Vaccine Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

390

192. Anti-Tumor Activity of Mesenchymal Stem Cells Producing IFN-α in a Mouse Melanoma Lung Metastasis Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 609 KB

english, 2007

391

193. Novel Adenoviral Vector Two-Step Transcription Amplification Expression System (TSTA) for Expressing CDK2-Associated Cell Cycle Regulators for Cancer Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 610 KB

english, 2007

392

194. Induction of Apoptosis in a Human Testicular Cancer Cell Line by Overexpression of REIC/Dkk-3 In Vitro and In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2007

393

195. Conditionally-Replicative Adenovaral Vectors with Bioluminescence-Based Replication Monitoring Capability for Lung Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 502 KB

english, 2007

394

197. mda-7 (INGN-241) Kills Chemoresistant Cancer Cells and Restores Chemosensitivity to Cisplatin

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 635 KB

english, 2007

395

198. Engineering Cytosine Deaminase/Uracil Phosphoribosyltransferase Fusion for Improved Cancer Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 635 KB

english, 2007

396

200. Identification of Genetics Alterations That Confer Resistance to Cisplatin in Ovarian Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

397

201. Replication Deficient Adenovirus Carrying Apolipoprotein (a) Kringles Suppress Tumor Growth in NSCLC Xenograft Tumor Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

398

202. Combined Effects of Ad5F35-TK/GCV Gene Therapy and Gemcitabine in Bladder Transitional Cell Carcinoma

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

399

203. Systemic Stable Radioprotection by Intravenous Administration of Manganese Superoxide Dismutase-Plasmid Liposomes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 606 KB

english, 2007

400

204. Gene Therapy of Pancreatic Carcinoma Based on Gemcitabine Chemosensitization Using Phosphorylating Fusion Gene Transfer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 606 KB

english, 2007

401

205. Knockdown of Lifeguard (LFG/FAIM2) in Glioblastoma Cells Increases Sensitivity to FasL and Doxorubicin

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 964 KB

english, 2007

402

206. Systemic Osteoprotegerin Gene Therapy Restores Tumor-Induced Bone Loss in a Therapeutic Model of Breast Cancer Bone Metastasis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 405 KB

english, 2007

403

207. Cell-Death Induction of Primary Melanocytes Cultures after Transfection of p(HSV-tk) by a Synthetic Reagent (KLN-47) and Followed by Addition of GCV

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 655 KB

english, 2007

404

208. Inducing Autophagy with a Gene Therapy Combined System Provides Successful Treatment Against Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 655 KB

english, 2007

405

209. Connexin 43 Expression in Glioblastoma for Suicide Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2007

406

210. Adenovirus-Mediated Thymidine Kinase Gene Transfer into Uterine Artery of Pregnant Rabbits Combined with Gansiclovir Treatment Does Not Affect the Fertility of the Does

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 628 KB

english, 2007

407

211. Restoration of Mutant p53 Function through the Alteration of Pre-mRNA Splicing Pattern

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 628 KB

english, 2007

408

213. NK4, Competitive Antagonist for HGF, Therapy Against Brain Tumors by Using with Replication-Incompetent HSV-1 Vector: 1764/4-/NK4

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

409

214. Genetic Engineering of a Human CD20-Specific Chimeric T-Cell Receptor and Co-Expression of a Linked Inducible Caspase-9 Suicide Gene

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 652 KB

english, 2007

410

215. Soluble Bi-Specific Adapter-Mediated Targeting of Herpes Simplex Virus Type 1 (HSV-1) to the Carcinoembryonic Antigen (CEA)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 652 KB

english, 2007

411

216. Oncolytic Adenoviruses Kill Breast Cancer Stem Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

412

217. Systemic Administration of a Replicating Adenovirus, Transcriptionally Targeted to Angiogenesis, Reduced Lung Metastases Burden in Cotton Rats

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 593 KB

english, 2007

413

218. Preclinical Studies on Matrix Metalloprotease-Activatable Measles Viruses for the Virotherapy of Solid Liver Tumours

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

414

219. Analysis of Mechanisms of Synergy between Irradiation and Oncolytic Adenoviruses in the Treatment of Hormone Refractory Prostate Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 665 KB

english, 2007

415

220. Sleeping Beauty-Mediated Antiangiogenic Gene Therapy for Metastatic Colorectal Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2007

416

221. Directed Evolution Generates a Novel Potent and Selective Ad3/Ad11p Chimeric Oncolytic Virus for the Treatment of Colon Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 651 KB

english, 2007

417

222. MicroRNA Signature of Human Prostate Cancer and Its Applicability in Identifying Early Relapse Disease

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 651 KB

english, 2007

418

223. VEGF-Targeted Artificial Zinc Finger Protein-Expressing Adenovirus Downregulates Angiogenesis and Leads to Enhanced Anti-Tumor Effects

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 651 KB

english, 2007

419

224. Systemic Administration of a Dual-Targeted Lentiviral Vector Leads to Specific Transduction of Prostate Cancer Bone Metastases In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 544 KB

english, 2007

420

225. A Targeted, Adenovirus-Mediated Histone Deacetylase (HDAC) Specific shRNA Approach Enhanced Cancer Radiation Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 544 KB

english, 2007

421

227. Ex Vivo Virus Production in Fresh Tissue Discs Predicts In Vivo Tumor Response in Xenograft Cancer Models Directly Injected with an Oncolytic HSV Mutant

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 697 KB

english, 2007

422

228. Relaxin Expression from Tumor-Targeting Adenoviruses and Its Intratumoral Spread, Apoptosis Induction, and Efficacy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2007

423

229. Identification of New Therapeutic Targets To Potentiate Oncolytic Adenovirus

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 660 KB

english, 2007

424

230. Prevention of Kupffer Cell Viral Clearance of Genetically and Non Genetically RGD Targeted Adenovirus, upon Systemic Administration, by the Use of Polinosinic Acidic

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 660 KB

english, 2007

425

231. Development of Antineovascular RNAi Cancer Therapy Targeting to Argonaute2

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2007

426

232. Potential Significance of OV Induced Cyr61 as a Biomarker for OV, and Its Impact on Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 673 KB

english, 2007

427

234. Inhibition of Melanoma Development by Single Dose Administration of hTERTC27 Viral Cocktail in C57BL/6 Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 644 KB

english, 2007

428

235. Chemoprotection and Persistent Dihydrofolate Reductase Transgene Expression in Primary and Secondary Transplant Recipients of Lentivirally-Transduced Marrow

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 644 KB

english, 2007

429

236. An Improved Human Carboxylesterase for Use in Enzyme/Prodrug Therapy Approaches with CPT-11

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2007

430

237. Efficient, Specific Propagation of a Transcriptionally Targeted Oncolytic Adenovirus To Treat Prostate Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 657 KB

english, 2007

431

238. Vector Integration Analysis in Mature T Cells Following PBL Gene Therapy in ADA-SCID Reveals a Cell-Type Specific Insertion Profile

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 657 KB

english, 2007

432

239. Insertional Mutagenesis of Retroviral Vectors Is Dependent on Transgenes in a Canine Stem Cell Gene Therapy Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 587 KB

english, 2007

433

241. Stable Reduction of CCR5 by RNA Interference through Hematopoietic Stem Cell Transplant in Non-Human Primates

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 581 KB

english, 2007

434

242. Adenovirus-Mediated Systemic Overexpression of Sonic Hedgehog Results in Expansion of Diaphyseal Trabecular Bone with Associated Increase in the Hematopoietic Stem Cell Niche

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 581 KB

english, 2007

435

243. Insertion Site Analysis Following Gammaretroviral Gene Therapy for Canine Leukocyte Adhesion Deficiency Reveals Lack of Genotoxicity

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 658 KB

english, 2007

436

245. Hematopoietic Stem Cell Gene Delivery: High Efficiency Gene Transfer to HSC In Vivo with Long-Term Expression of Anti-HIV Transgenes after Intramarrow Injection SV40-Derived Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2007

437

246. Very High Levels of Expression of the O6 Methylguanine-DNA-Methyltransferase P140K Mutant Results in an In Vivo Engraftment Defect

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 683 KB

english, 2007

438

248. Evidence of Globin Lentiviral Vector-Induced Genotoxicity in a Murine Model of Sickle Cell Disease

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 600 KB

english, 2007

439

249. Gene Therapy in Adenosine Deaminase-Deficient Children with Autologous Bone Marrow Cells Transduced with Two Retroviral Vectors after Withdrawal of Enzyme Replacement Treatment and Low-Dose Chemotherapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 601 KB

english, 2007

440

250. Lentiviral-Transduced HSC Lead to Long-Term Correction of β-Thalassemia by In Vivo Selection of Erythroid Progenitors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 628 KB

english, 2007

441

251. Development of Leukemia/Lymphoma after the Long Latency Period in an X-SCID Mouse Model Treated by Retroviral Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 628 KB

english, 2007

442

252. Immune Responses Against Tetracycline-Dependent Transactivators Do Not Affect Long-Term Transgene Expression Delivered by a Helper-Dependent Adenoviral Vector (HC-Ad)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2007

443

253. Regulation of Factor VIII-Specific Immune Responses in a Plasmid DNA Treated Hemophilia A Mouse Model by Transgenic FOXP3+CD4+ Regulatory T Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 668 KB

english, 2007

444

255. Cross Presentation of AAV2 Capsids Activates Cytotoxic T Cells and Hinders Muscle-Directed Gene Transfer but Does Not Render Hepatocytes Effective Cytolytic Targets

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 649 KB

english, 2007

445

256. Ultrasound Guided Gene Transfer to the Fetal Thymus Results in Thymic Epithelial Cell Transduction and Deletion of Transgene Specific T Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 649 KB

english, 2007

446

257. Characteristic of Responsive CD8+ T Cells to AAV 2/8 and Ad C7 HIV Gag Vector Vaccines

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2007

447

260. Tolerance Induction to FIX in Mice with Pre-Existing Anti-FIX Immunity Following Direct Intramuscular Injection of AAV

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 655 KB

english, 2007

448

261. Antigen-Specific Tolerance Induction by Transcriptional Targeting of Dendritic Cells with a Novel Lentiviral Vector

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 655 KB

english, 2007

449

262. Suppression of Hyperglycemia in Nod Mice after Inoculation with Recombinant Vaccinia Viruses

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 655 KB

english, 2007

450

264. Induction of FIX Tolerance by Direct Intramuscular Injection of AAV Is AAV-Dose/FIX-Level Dependent

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 479 KB

english, 2007

451

265. Pre-Existing Immunity with Either Th1 or Th2 Predominance Inhibits Expression of Transgene in Skeletal Muscle of Immune Competent Animals

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 479 KB

english, 2007

452

266. Creating Retroviral Vector Encoding Two Homologous Chimeric Immune Receptors with Degenerated Codons

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 551 KB

english, 2007

453

268. Transcriptional and Post-Translational Regulation System for Hypoxia Specific Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 551 KB

english, 2007

454

269. Flow Cytometric Analysis of DNA Binding and Cleavage by Cell Surface-Displayed Homing Endonucleases

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 566 KB

english, 2007

455

270. Gene Transfer of an Engineered Transcription Factor Promoting Expression of VEGF-A Accelerates Rehabilitation of the Crushed Recurrent Laryngeal Nerve

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 566 KB

english, 2007

456

271. Expression of IGF1 Receptor Ribozyme and IGFBP3 To Inhibit Rat Glioma Cell Growth

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2007

457

272. Incorporation of a Prostate-Specific Amplification Loop with FasL and TRAIL Expression To Boost Prostate Cancer Killing

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 606 KB

english, 2007

458

273. Enhanced Hypoxia Specific Expression Activity of the Epo Enhancer and SV40 Promoter by Co-Transfection of the HIF-1a Gene

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 606 KB

english, 2007

459

274. Correction of Albinism Mutations by Targeted Genomic Rearrangements Using Engineered Zinc Finger Endonucleases

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 606 KB

english, 2007

460

275. Effect of the Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element (WPRE) on Transgene Expression Controlled by the Human Synapsin 1 Gene Promoter Following Adenoviral-Mediated Gene Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

461

276. Synthesis and Evaluation of Chemically Modified Peptide Nucleic Acids as Potential beta-Globin IVS2 Gene-Targeting Agents

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 610 KB

english, 2007

462

277. A Highly Sensitive and Specific System for Large-Scale Breast Cancer Gene Expression Profiling

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 610 KB

english, 2007

463

278. Conditionally Replicating Vector Mediated Transcriptional Silencing of HIV-1

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

464

279. A Threshold Exists for Expression of Short Hairpin RNA (shRNA) in Liver Using Gutless Adenovirus Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 619 KB

english, 2007

465

280. Determination of an Induced Cellular Immune Profile — Insights into Control of Viral Replication

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 619 KB

english, 2007

466

281. Characterization of FLP Recombinase Using Adenovirus Vector and Application for Gene Regulation in Mammalian Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

467

282. A Quasi-Lentiviral Green Fluorescent Protein Reporter Exhibits Nuclear Export Features of Late Human Immunodeficiency Virus Type 1 Transcripts

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 622 KB

english, 2007

468

283. Constructoin of Artificial Promoters That Are Responstive to X-Ray Irradiation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

469

284. Controlled Expression of an Inwardly-Rectifying Potassium Channel for Neuromodulation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

470

285. Construction and Testing of a Versatile One-Plasmid Regulated Expression System in Mice Using the Interferon beta Gene

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 590 KB

english, 2007

471

286. In Vitro Studies on the Redirection of Human Growth Hormone Sorting

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 589 KB

english, 2007

472

287. An Omega-Based Bacterial Selection System for Engineering Artificial Zinc Finger Proteins

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2007

473

288. Structure-Based Redesign of the Dimerization Interface Reduces the Toxicity of Zinc Finger Nucleases

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 583 KB

english, 2007

474

289. Influence of Donor DNA Design on Uninduced and Double-Strand-Break-Induced Gene Correction

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 583 KB

english, 2007

475

290. Transduction of a Mammary Epithelial Stem Cell Population Via Early Gestational Intra-Amniotic Gene Transfer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

476

291. Phase 1 Human Trial of Autologous Mesenchymal Stem Cell Transplantation for the Treatment of Decompensated Cirrhosis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 616 KB

english, 2007

477

292. Long-Term Lentiviral Vector-Mediated Gene Marking of the Human Hematopoietic System in Humanized Rag2−/−γc−/− (RAG-hu) Mice and Applications for HIV-1 Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 616 KB

english, 2007

478

293. Suicide Gene-Mediated Conditional Removal of CNS Tumors-Derived from CNS Transplanted Embryonic Stem Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

479

294. Cell Cycling Prior to Sex Cord Closure Places Male Germ Cells at Risk of Transduction

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 639 KB

english, 2007

480

295. The K5 Promoter Enhances Gene Expression in Skin Stem Cell Populations after Early Gestational Intra-Amniotic Gene Transfer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

481

297. A Comparison of Transduction Efficiency and Long-Term Repopulating Capacity of Lentiviral Transduced SLAM Versus KSL-Enriched HSC Using an Abbreviated Transduction Protocol

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

482

298. Self-Renewal and Differentiation of Human Mesenchymal Stem Cells from Single Cell Clonal Assays

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 620 KB

english, 2007

483

299. Hepatocyte Propagation In Vivo for Liver Tissue Engineering

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 620 KB

english, 2007

484

300. Development of Megakaryocyte-Specific Lentiviral Vectors for Gene Therapy of Platelet Disorders

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

485

302. Intraesophageal Manganese Superoxide Dismutase Plamsid/Liposome (MnSOD) Administration before Irradiation Increases Intravenous Engraftment of Esophageal Stem Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2007

486

303. Efficient Gene Transfer into Long-Term Repopulating Hematopoietic Stem Cells from Clinically Relevant Sources

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 635 KB

english, 2007

487

304. A Transformed Cell Population Derived from Long Term Cultured Mesenchymal Stem Cells Has No Functional Effect after Transplantation into the Injured Heart

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 635 KB

english, 2007

488

305. Surface Epitopes Involved in Cell Motility and Tumor Progression Are Expressed in Low Density Cultures but Not in Confluent Cultures of Human Multipotent Stromal Cells (hMSCs)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

489

306. Testing Large-Scale Lentiviral Vector Preparations for Replication Competent Lentivirus

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 586 KB

english, 2007

490

307. Generation of Lentivirus Vectors Using Recombinant Baculoviruses

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 586 KB

english, 2007

491

308. Titer and Long Term Stability of Retroviral Titers Produced in Murine Based Producer Cell Lines

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2007

492

309. Plasmid DNA Production in a Wave Bioreactor under cGMP Conditions

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 609 KB

english, 2007

493

310. A Rapid, Accurate and Precise Assay System To Analyze the Quality and the Quantity of Clinical Grade HSV Vector Stocks

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 609 KB

english, 2007

494

311. Development of a High Cell Density Process for cGMP Production of VRX496 Modified HIV Infected CD4+ T Lymphocytes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

495

312. Large Scale Lentiviral Vector Production in a GMP Facilty

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 613 KB

english, 2007

496

313. Production of Ad/AAV-Hybrids Encoding Proteins That Inhibit Viral Propagation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 613 KB

english, 2007

497

314. Retronectin Stimulation for the In Vitro Generation of Human Tumor-Reactive T Lymphocytes for Adoptive T Cell Transfer Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

498

316. The Human Papillomavirus E1 Gene Interferes with E2 and E6 Helper Functions for Adeno-Associated Virus Replication

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 636 KB

english, 2007

499

317. Refinement of Laboratory Protocols for AAVrh.10 Production into Production Batch Records Suitable for Production of Clinical Grade Vector

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

500

319. Inactivation of Herpes Simplex Viruses Following the Manufacturing of Recombinant Adeno-Associated Virus Vector by the Herpes Simplex Virus Co-Infection Method

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 623 KB

english, 2007

501

320. Commissioning of an Aseptic Processing Area for Clinical Production of Adenoviral Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 623 KB

english, 2007

502

322. Transient Expression of WHIM-Type Mutant CXCR4 Human Hematopoietic Stem Cells Mediated by Integration Defective Lentivirus Vector Enhances Engraftment in the NOD/SCID Mouse Xenograft Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

503

324. Promoter Analysis by Transduction of Fetal and Neonatal Mice by Lentiviral Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

504

325. LTR Attachment Site Mutant Non-Integrating Lentiviral Vectors Provide Greater Levels of Gene Expression

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

505

327. Exploiting the Terminal Repeats of Lentiviral and Gammaretroviral Vectors To Block Both Transcriptional Readthrough and Enhancer Interactions

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

506

328. A Mechanistic Study of HIV-1 SIN Vector Mobilization To Address Unanticipated Biosafety Risks

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 638 KB

english, 2007

507

329. Role of the Factor X (FX) Light Chain in Adenovirus Binding and Serine Protease Exosite in Mediating Cell Transduction

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

508

330. An In Vivo Model To Evaluate Hepatic Targeting of Adenovirus by Coagulation Factor X

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 616 KB

english, 2007

509

331. Comparison of Blood Interaction and Organ Biodistribution for Adenoviruses from Subspecies B, C, E and F

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 616 KB

english, 2007

510

332. Alteration of Adenoviral Liver Tropism Following Hexon Protein Modification

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

511

333. Converging Evidence for a Critical Role of the Diameter of Sinusoidal Fenestrae in Hepatocyte Transduction after Adenoviral Gene Transfer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 629 KB

english, 2007

512

334. Efficient Gene Transfer in Cultured Aortic Smooth Muscle and Endothelial Cells by Magnetically Responsive Nanoparticles Impregnated with Adenovirus

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2007

513

336. Protein IX-Modified Adenovirus Gene Transfer Vectors Can Efficiently Be Targeted to LRP by the Receptor-Associated Protein RAP

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 565 KB

english, 2007

514

337. Mutational Derivatives of PhiC31 Integrase with Increased Efficiency and Specificity

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 616 KB

english, 2007

515

338. Terminal Inverted Repeats of the Sleeping Beauty DNA Transposon Possess Residual Promoter-Like Activities

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 616 KB

english, 2007

516

339. Autoregulation of Transposition of Sleeping Beauty Transposons by Ubiquitous N-Terminal, Dominant Negative Peptides

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2007

517

340. Silencing of Episomal Transgene Expression in Liver by Plasmid Bacterial Backbone DNA Is Associated with Histone Modifications but Independent of CpG Methylation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 571 KB

english, 2007

518

341. Exogenous Plasmid DNA Sequences Differentially Affect Episomal Transgene Silencing in Liver and Muscle

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 570 KB

english, 2007

519

343. Deletion of CpG Motifs from Plasmid DNA for Sustained Transgene Expression In Vivo: Evaluation Based on a Statistical Analysis of the Expression Profile

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

520

344. Development of S-MAR Plasmid Vectors for Persistent Expression and Maintenance, In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

521

345. A Hepatitis B Virus Protein X – Phenylalanine Hydroxylase Fusion Protein Is Detected in Pahenu2 Mice Treated with AAV-WPRE Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 593 KB

english, 2007

522

346. Insulin Replacement Gene Therapy for Type 1 Diabetes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 593 KB

english, 2007

523

347. Therapeutic Effects of Bone Marrow Transplantation for Metachromatic Leukodystrophy Using HoxB4 Over-Expressing Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 572 KB

english, 2007

524

348. Biodistribution of AAVI-LPLS447X Vector Sequences after Intramuscular Administration to Lipoprotein Lipase Deficient Patients

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 572 KB

english, 2007

525

349. Very Few Vector Particles of a Small-Genome AAV Vector Prolong Survival in Glycogen Storage Disease Type la Mice and Dogs

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

526

350. Hematopoietic Stem Cell Based Gene Therapy for the Treatment of Metachromatic Leukodystrophy: Towards Clinical Testing

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 644 KB

english, 2007

527

351. Aortic Disease in Mucopolysaccharidosis I Mice Is Due to Upregulation of Elastase Proteins and Can Be Prevented with Neonatal Gene Therapy in Mice and Dogs

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

528

352. Correction of Hypoglycemia Following Gene Therapy in Dogs Affected with Glycogen Storage Disease Type la

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 613 KB

english, 2007

529

353. Ad2-Mediated Expression of a Constitutively Stable Hypoxic Inducible Factor-1α Enhances Collateral Development and Reduces Vascular Leakage in a Diabetic Rat Model of Hindlimb Ischemia

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 613 KB

english, 2007

530

354. Adenoviral eNOS-Eluting Stents Result in Accelerated Re-Endothelialisation and a Reduction in Neointima Formation in an In Vivo Rabbiat Iliac Artery Stent Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

531

355. Novel Gene Transfer Vectors To Modulate the Renin Angiotensin System

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 632 KB

english, 2007

532

356. Use of Gene Transfer To Identify Cell and Tissue Specific Splicing Factors That Dictate Alternative Splicing of the Human VEGF Gene

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 632 KB

english, 2007

533

357. Bone Marrow Cells Recruited through the Neuropilin-1 Receptor Are Essential To Promote Arterial Formation at the Sites of Adult Neoangiogenesis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

534

358. Helper-Dependent Adenovirus-Mediated LDLR Gene Therapy Reverses Hypercholesterolemia in LDLR-Deficient Rhesus Monkeys In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

535

359. AAV Vector-Mediated Sustained Expression of Prostacyclin Synthase Ameliorates Obesity in Zucker Fatty Rats

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

536

360. Over Expression of the Angiotensin Type 2 Receptor in the Rostral Ventrolateral Medulla (RVLM) Decreases Basal Blood Pressure in Normotensive Rats

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 634 KB

english, 2007

537

361. Genetic Modification of T Cells To Prevent CMV Infection after Umbilical Cord Blood Transplantation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2007

538

362. Prolonged and Liver Specific Expression of IL-12 Breaks Tolerance Against Viral Antigens and Induces a Marked and Sustained Antiviral Effect in Woodchucks with Chronic Viral Hepatitis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 521 KB

english, 2007

539

363. MicroRNA-Like Hairpin Sequences Capable of Inhibiting HBV Replication Efficiently In Vitro and In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2007

540

364. Inhibition of HIV-1 Replication with miRNA-siRNA Hybrids Expressed from RNA Polymerase Promoters

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 660 KB

english, 2007

541

365. Combinatorial Gene Therapy To Inhibit HIV: Improving the Therapeutic Effect by Adding Transgenes Targeting Different Stages in the HIV-1 Replication Cycle

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 660 KB

english, 2007

542

367. Preventing HIV-1 Tat-lnduced Apoptosis Using Antioxidant Enzymes: Mechanistic and Therapeutic Implications

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 532 KB

english, 2007

543

368. Cytotoxic T Lymphocyte Therapy for the Treatment and Prevention of Adenovirus Infection after Stem Cell Transplant

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 533 KB

english, 2007

544

369. Selecting Highly Affine and Well Expressed TCRs for Gene Therapy of Melanoma

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 628 KB

english, 2007

545

370. Antigen Dose-Responsiveness and Immunoselectivity of CD8+ T Cells Bearing Chimeric T Cell Receptors Specific for CD20 and CD22: Implications for Immunotherapy of B Cell Malignancies

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 628 KB

english, 2007

546

371. Lentivirally Engineered Primary Human Peripheral Blood Lymphocytes with Anti-CEA Chimeric Immune Receptor Efficiently Recognize and Lyse CEA* Tumor Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2007

547

372. A First-in-Human Clinical Trial of Adoptive Therapy Using CD19-Specific Chimeric Antigen Receptor Re-Directed T Cells for Recurrent/Refractory Follicular Lymphoma

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 546 KB

english, 2007

548

373. “Designer” Cellular Immunotherapy: Zinc Finger Nucleases Generate Glucocorticoid Receptor Negative IL-13 Zetakine Expressing CD8+ T-Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 546 KB

english, 2007

549

374. Investigation of Therapeutic Immune-Responses to Cancer In Vivo: Tracking Lymphocytes with Transgenic T-Cell-Receptor Specific to a Melanoma Antigen by PET Imaging

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 588 KB

english, 2007

550

375. Improved Homing of Antigen-Specific T Cells to Hodgkin's Tumor Cells by Forced Expression of CCR4 Receptor

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 588 KB

english, 2007

551

376. Phase 1/2a, Dose-Escalation, Safety and Proof of Concept Study of Intravesical BC-819 in Patients with Superficial Bladder Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 562 KB

english, 2007

552

377. Targeted Delivery of lnterferon-α by Gene Modified Hematopoietic Stem Cells Inhibits Tumor Growth

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 562 KB

english, 2007

553

378. Enhanced Tumor Cell Killing in a Human Glioblastoma Xenograft Model with TRAIL Expressed from an Engineered Adenovirus Vector

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 628 KB

english, 2007

554

379. Harnessing the P53 Pathway To Drive Viral Expression and Inhibit Tumor Growth Via Strategic Promoter/Transgene Combinations

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 628 KB

english, 2007

555

380. Clinical Experience with the mda-7/IL-24 Tumor Suppressor

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

556

382. Clinical Investigation of “Bifunctional” shRNA Knockdown of Acid Ceramidase

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 620 KB

english, 2007

557

383. Efficient Targeting of AAV Vectors to Tumor-Associated Angiogenic Vasculature Following Intravascular Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 555 KB

english, 2007

558

384. Telomerase-Specific Virotherapy Targeting Lymph Node Metastasis of Gastrointestinal Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 555 KB

english, 2007

559

385. Nox2-Dependent Endosomal H2O2 Facilitates rAAV2 Infection by Activating Capsid PLA2

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 586 KB

english, 2007

560

387. Sequencing of rAAV Genome Termini in Wild Type and SCID Mouse Tissues Unravels a Role of Artemis/DNA-PKcs in Opening AAV-ITR Hairpins In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

561

388. Adeno-Associated Virus 2-Mediated Gene Transfer: Tyrosine-Phosphorylation of Capsid Proteins and Its Consequences on Transgene Expression

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 626 KB

english, 2007

562

389. Subcellular Trafficking of Recombinant AAV: Nucleolar Accumulation of Capsids Is Unique to Infectious Virions

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 626 KB

english, 2007

563

390. Involvement of Growth Factor Receptors in Heparin Mediated Enhanced Transduction of AAV3b Based Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 571 KB

english, 2007

564

392. Robust Induction of Type I Interferons Immediately after Systemic Delivery of HSV Amplicon Vectors Elicits Infiltration of Immune Cells and Suppresses Transcription of the Vector-Encoded Transgene

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 569 KB

english, 2007

565

393. Targeting of Metabolically Biotinylated Baculoviruses

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 568 KB

english, 2007

566

395. Monitoring Sarcoma Response to Systemic Gene Therapy with a Targeted Adeno-Associated Virus/Phage: AAVP

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 607 KB

english, 2007

567

396. A Tetracycline Regulatable Oncolytic HSV-1 Recombinant for Tumor Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 607 KB

english, 2007

568

397. Expression and Distribution of Compacted-DNA Nanoparticles in the Developing Retina

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

569

398. Non-Viral Gene Delivery to the Primate CNS: A Model for Pre-Operative Neuroprotection

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 614 KB

english, 2007

570

399. Transposition of Anti-HIV Transgenes rhTRIM5α, mAPOBEC 3, Anti-CXCR4 and CCR5 siRNAs by Sleeping Beauty (SB) Transposon System for HIV Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 614 KB

english, 2007

571

401. Binding of Oligodeoxynucleotides to the beta-(1->3)-D-Glucan Schizophyllan Increases Their Stability in Blood and Potentiates the Efficacy of Antisense Therapy In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2007

572

402. Comparison of Intravesical lnterleukin-12 Gene Therapy and Intravesical BCG Therapy in an Orthotopic Bladder Cancer Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 565 KB

english, 2007

573

403. A Novel In-Vivo Approach for AAV-Mediated Gene Therapy of Hemophilia B Using Salivary Glands as a Depot Organ

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 565 KB

english, 2007

574

404. Partial Correction of the FVIII Deficit in Hemophilia A Mice Using Minicircle DNA Vectors Expressing Pre-Trans-Splicing Molecules

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2007

575

405. A microRNA-Regulated Lentiviral Vector Mediates Stable Correction of Hemophilia B Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 628 KB

english, 2007

576

406. Long-Term Phenotypic Correction of Murine Hemophilia A and Immunological Differences of Bioengineered FVIII Variants Delivered by Helper-Dependent Adenoviral Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 628 KB

english, 2007

577

407. A Clinically-Relevant Gene Therapy Strategy for Hemophilia A: Non-Myeloablative Transplantation of Hematopoietic Stem Cells Transduced with a High-Expression Factor VIII Transgene

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 529 KB

english, 2007

578

408. Correction of the Factor VIII Deficiency in Hemophilia A Mice with Pre-Existing Anti-Factor VIII Inhibitors by Transplantation of Genetically-Modified Hematopoietic Stem Cells Expressing Porcine Factor VIII

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 529 KB

english, 2007

579

409. Microdystrophin Expression in Mice Reveals Novel Roles for Dystrophin at the Myotendinous and Neuromuscular Junctions

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 583 KB

english, 2007

580

410. In Utero Delivery of Adenovirus Encoded TGF-β3 Rescues Cleft Palate in a TGF-β3 Knockout Mouse

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 583 KB

english, 2007

581

412. Phase l-lla Gene Therapy Protocol for LGMD 2C: Clinical Strategy and Implications

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 614 KB

english, 2007

582

413. AAV-Mediated Gene Targeting of COL1A2 Exon 2 in Mesenchymal Stem Cells from Individuals with Osteogenesis Imperfecta

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 614 KB

english, 2007

583

414. Sustained Efficacy through Adeno-Associated Virus Vector-Mediated Gene Replacement in Advanced Pompe Disease

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 622 KB

english, 2007

584

415. AAV6.2: An Efficient and Safe Gene Therapy Clinical Candidate for the Treatment of Cystic Fibrosis Airway Disease

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 622 KB

english, 2007

585

416. Significant Airway Transduction after In Utero Administration of a Gp64 Pseudotyped Lentiviral Vector

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

586

417. Bronchoscope-Guided, Targeted Lobar Aersolization of HDAd into Northuman Primate Lungs Results in Uniform, High Level Pulmonary Transduction, Long Term Transgene Expression and Negligible Toxicity

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 604 KB

english, 2007

587

418. Lung-Directed Gene Therapy for Human Alpha-1 Antitrypsin Deficiency Using AAV6 Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

588

419. Correction of CFTR Function by Segmental Trans-Splicing

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 625 KB

english, 2007

589

421. Recruitment by the Liver of Genetically Modified Endothelial Progenitor Cells in Models of Acute and Chronic Liver Damage

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 624 KB

english, 2007

590

423. Magnetic Resonance Imaging Reveals Hematopoietic Stem/Progenitor Cells Homing to the Brain of Mice Affected by Metachromatic Leukodystrophy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

591

424. Sustained Engraftment of MGMTP140K Gene-Modified Dog Hematopoietic Cells in Primary and Secondary Recipients

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 639 KB

english, 2007

592

425. Production of Transgenic Cloned Domestic Cat Embryos by Lentivirus-Mediated Transgenesis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

593

426. Highly-Efficient Genome Modification in Human Mesenchymal Stem Cells Using Engineered Zinc Finger Nucleases

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 600 KB

english, 2007

594

427. Validation of a Large-Scale Semi-Closed System for the Manufacture of Autologous T Cells Genetically Targeted to the B Cell-Specific Antigen CD19 for a Phase I Trial in Patients with Chronic Lymphocytic Leukemia

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 600 KB

english, 2007

595

428. Development of a Safe High-Titer Packaging System Based upon FeLV

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

596

429. Development of a cGMP Production Process for rAAV1 Vectors Produced Via Baculovirus Expression

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 640 KB

english, 2007

597

433. Cone-Targeted Gene Therapy by AAV

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 549 KB

english, 2007

598

434. MicroRNA-Regulated Lentiviral Vectors Drive Robust Tissue-, Lineage- and Developmental Stage-Specific Gene Expression in Hematopoietic, Neural and Embryonic Stem Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 549 KB

english, 2007

599

435. CNS Viral Vector Delivery under Real-Time Imaging Control

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 649 KB

english, 2007

600

436. Targeted Disruption of CCR5 Using Engineered Zinc Finger Protein Nucleases Provides In Vivo Protection from HIV

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 649 KB

english, 2007

601

437. Optimization of Capsid-lncorporated Antigens for an Improved Adenovirus Vaccine Approach

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

602

438. Enhancement of Therapeutic Effect with Replication-Competent Retrovirus Vectors Using Helper-Dependent Adenovirus

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 623 KB

english, 2007

603

439. Promoter Control of Gene Expression in Adenovectors Delivered to the Vestibular System

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 623 KB

english, 2007

604

440. A New Infectivity-Enhanced “Delta-24” Oncolytic Adenovirus with Capsid-lncorporated Dual Imaging Modality Reporter for a Dynamic Fluorographic and SPECT/PET-Based Imaging

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

605

443. Systemic Dissemination of the Replication-Competent Oncolytic Adenovirus Telomelysin (OBP-301) Following Intratumoral Injection

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 569 KB

english, 2007

606

444. YB-1 as a Target for the Development of Oncolytic Adenoviruses

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 569 KB

english, 2007

607

445. Effects of Exogenous p53 on Potency and Safety of Oncolytic Adenovirus

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 569 KB

english, 2007

608

447. Survivin-Responsive Conditionally Replicating Adenovirus Additionally Regulated with Cancer-Specific Promoter Achieved More Strict Cancer Specificity without Reducing Anti-Cancer Effect

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

609

448. Adeno-hTERT-E1 A, a Highly Oncolytic, hTERT Promoter-Regulated Replication-Conditional Adenovirus

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

610

449. Effect of Preimmunization and Transient Immunosupression with CsA in Hepatic Adenovector Transduction in Cirrhotic Rats

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 565 KB

english, 2007

611

450. Further Study of Gene Transduction into a Subset of Rat Dendritic Cells (DC) Generated from a Long Term Culture of Bone Marrow Cells: Apparent Resistance of Plasmacytoid DC to Gene Transduction by Adenoviral Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 565 KB

english, 2007

612

451. Generation of Apolipoprotein A-l Adenoviral Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2007

613

452. Effect of TBRIIΔcyt Transduction in Pro-Fibrogenic Gene Expression in Activated Hepatic Stellate Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 594 KB

english, 2007

614

453. Rapid Identification and Classification of Adenoviral Serotypes by Mass Spectrometry

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 594 KB

english, 2007

615

454. Adenylyl Cyclase Type VI Regulates Akt Activity through a PH Domain Leucine-Rich Repeat Protein Phosphatase

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 607 KB

english, 2007

616

455. Plasmin Has an Important Role in Regulate Profibrogenic Molecules in HSC

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 607 KB

english, 2007

617

456. An In-Vitro Assay To Assess Secreted Osteogenic Factors from Genetically Engineered Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2007

618

457. Replicative Adenovirus with Enhanced Tumor Specificity and Oncolysis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 582 KB

english, 2007

619

458. Hexamethylene Bisacetamide Addition during Vector Packaging Leads to Reduced Helper Virus-Free HSV-1 Amplicon Expression Titers Via Suppression of Particle-Associated ICPO

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 583 KB

english, 2007

620

459. The HSV-2 Protein ICP10PK Protects PC12 Cells from MPP+-Mnduced Apoptosis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 582 KB

english, 2007

621

460. Imaging Transcriptional Activation of Gliomas in the Indicator Infectious BAC (iiBAC) of SPARC

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 600 KB

english, 2007

622

461. Functional Genomic Analysis of Oncolytic HSV Infection in Human Cancer Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 600 KB

english, 2007

623

462. Minimal Risk of Herpes Simplex Virus Latency Following Intravenous or Intracerebral Injection of an ICP6-Deleted Oncolytic HSV Expessing CYP2B1 (rRp450) Is Not Increased by Cyclophosphamide Co-Administration

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1017 KB

english, 2007

624

463. Generation of HSV Vectors Using a Highly Efficient BAC Homologous DNA Recombination

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 457 KB

english, 2007

625

464. SPECT/CT Imaging of Baculovirus Biodistribution in Rat Shows Kidneys To Be a Promising Target for Intraperitoneal Gene Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 619 KB

english, 2007

626

465. Baculovirus Vectors Displaying Tumor-Homing Peptides: Binding and Entry Kinetics in Human Cancer Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 619 KB

english, 2007

627

466. Antiviral Effect Caused by Baculovirus Transduction Hampers Subsequent Transgene Expression in Rat Articular Chondrocytes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 619 KB

english, 2007

628

467. Baculovirus-lnduced Intranuclear Alterations in Human Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 610 KB

english, 2007

629

468. A 96-Well Baculovirus Generation Platform for High-Throughput Gene Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 610 KB

english, 2007

630

469. SV40 Vectors Expressing Insulin-Like Growth Factor I Revert Liver Cirrhosis in Rats

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 610 KB

english, 2007

631

470. Aerosol Delivery of Lentivius-CTMP Suppressed Lung Cancer Growth through Controlling Akt-Related Signals in Lungs of K-ras Null Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

632

471. Baculovirus as a New Gene Delivery Vector for Stem Cells Engineering and Bone Tissue Engineering

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

633

475. Minicircle Plasmid Containing the Human Manganese Superoxide Dismutase (MnSOD) Transgene Confers Radioprotection to Cells In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 643 KB

english, 2007

634

476. Group II Intron Mediated Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2007

635

478. Development and Production of Marker-Free Non-Viral Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2007

636

479. Antisense Oligonucleotide Selection for Exon Skipping by a Readout Reporter System with High Capacity and Specificity

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 550 KB

english, 2007

637

480. Designing a Targeted Plasmid DNA in Absence of Synthetic Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 550 KB

english, 2007

638

481. Structure-Based Prediction of Insertion-Site Preferences into Chromosomes of Vectors Used for Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 585 KB

english, 2007

639

482. Construction and Testing of a Liver-Directed Targeting Tether for Tissue-Specific Delivery of Sleeping Beauty Transposons

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 585 KB

english, 2007

640

483. Phage C31 Integrase Induced Chromosomal Rearrangements in Normal Human Fibroblasts Involves DNA Damage Response

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 585 KB

english, 2007

641

484. Safety of ΦC31 Integrase Expression in Mouse Liver Following Hydrodynamic Injection

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 643 KB

english, 2007

642

485. Analysis of the Transfection Behaviour of Supercoiled Plasmid DNA Concatemers In Vitro

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 643 KB

english, 2007

643

486. Rapid Deployment Plasmid Production Process, Combining Inducible High Yield Fed-Batch Fermentation Process with Novel Autolytic Plasmid DNA Purification

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2007

644

487. Amplified IL-15 Expression Vector for Cancer Immuno-Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 494 KB

english, 2007

645

489. Temporal Expression Patterns of Various Growth Factors during the Cutaneous Wound Healing of Streptozotocin Diabetic Mice Provoked by Non-Viral VEGF165 Gene Therapy Via Sonoporation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 945 KB

english, 2007

646

490. Lipoplex Loaded Microbubbles for Gene Delivery: A Trojan Horse Controlled by Ultrasound

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 498 KB

english, 2007

647

491. Local Delivery of Plasmid DNA into Skeletal Muscles by Echo-Contrast Gas Entrapping Liposomes, “Bubble Liposomes”

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2007

648

492. Comparison of the Sonoporation with the Cationic Polymer and Liposome by In-Vitro Gene Transfection Efficiencies and Toxicities

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 591 KB

english, 2007

649

493. Agitation during siRNA-Cationic Liposome (CL) Complex Formation Is a Key Step To Improve In Vitro RNA Interference by Lipofection

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2007

650

494. Towards Non-Viral Gene Therapy with Plasmid DNA Encapsulated in Pegylated Immuno-Liposomes (PILs)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 568 KB

english, 2007

651

495. Thermosensitive Non-Viral Vectors: Combination of Gene Therapy with Hyperthermia

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 568 KB

english, 2007

652

496. The Novel Peptide Transporter System of p14 and p16 to Prostate Cancer Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 568 KB

english, 2007

653

497. A Dose-Ranging Study of AAV2/1/ SERCA2a Delivered Via the V-Focus Cardiac Delivery System in an Ovine Pacing Model of Heart Failure

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2007

654

498. Hydrodynamics-Based Transfection Procedure Transiently Activates Expression of Preexistent Transgene

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 624 KB

english, 2007

655

500. High Efficacy of High and Low Voltage Pulse Combinations for Gene Electrotransfer in Muscle, Liver, Tumor and Skin

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2007

656

501. Cyclic Stretch Following Electroporation Enhances Gene Transfer to the Lung

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 547 KB

english, 2007

657

502. An Endoscopic Tool for Targetted Gene and Drug Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1004 KB

english, 2007

658

503. A CE-Marked Automated Device for Electroporation-Enhanced DNA Delivery in Humans

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 499 KB

english, 2007

659

504. A Single-Needle Device for Electroporation-Enhanced DNA Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 499 KB

english, 2007

660

505. Intracellular Trafficking of Oligonucleotides Delivered with Poly(Glycoamidoamine)s

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1010 KB

english, 2007

661

507. Nuclear Accumulation of Plasmid DNA Can Be Enhanced by Non-Selective Gating of the Nuclear Pore

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2007

662

508. Intracellular Trafficking of DNA Nanoparticle and Nucleolin Antibody

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 585 KB

english, 2007

663

509. Fusogenic Segments of Glycoprotein H from Herpes Simplex Virus Enhance Transfection Efficiency of Cationic Liposomes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 585 KB

english, 2007

664

510. An AlphaScreen Based Assay To Analyse Binding Properties of Engineered Histones with Application in Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2007

665

511. Identification of Proteins Interacting with DNA Complex in Cytosol

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 592 KB

english, 2007

666

512. Comparison of Two Nuclei Isolation Protocols for the Determination of the Number of Plasmid DNA Copies in the Nucleus after Transfection

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 592 KB

english, 2007

667

513. Selective Penetration of Cancer Cells by Cupredoxins and Derivative Peptides as Potential Vectors for Gene Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 636 KB

english, 2007

668

514. Overcoming Hurdles of Nonviral Gene Delivery to Nonproliferating Cells by RNA Based Gene Transfer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 636 KB

english, 2007

669

515. Novel Hybrid Vectors for Gene Delivery: Exploiting Viral Strategies with Non-Viral Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

670

517. DNA Nanoparticles Labeled with Tunable Nanocrystals: Demonstration of Coupling and Visualization by Fluorescence Microscopy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 626 KB

english, 2007

671

518. Nuclease Stability of siRNA and DNA Condensed with PEGylated Polylysine

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 590 KB

english, 2007

672

519. DNA Delivery Was Enhanced by Novel Protein Transduction Domain, Hph-1

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 590 KB

english, 2007

673

520. Gene Transfection to Cells from Apical Side

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 590 KB

english, 2007

674

521. Isolation of Human Fetal Myoblasts and Its Application for Microencapsulated Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 617 KB

english, 2007

675

522. An Inhibitor of the Fumarylacetoacetate Hydrolase (Fah) To Select for Gene Corrected Hepatocytes In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 617 KB

english, 2007

676

524. Non-Viral Gene Transfer Enhanced by a Nuclear Localizing Peptide

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 586 KB

english, 2007

677

525. Evaluation of Formulation and Stability of Investigational Gene Transfer Vectors for Leber Congenital Amaurosis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 586 KB

english, 2007

678

526. Antioxidant Gene Delivery To Mitigate Neurotoxicity in an Experimental Model of Chronic Brain Damage Due to HIV-1 Envelope Glycoprotein gp120

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

679

527. Macrophage Delivery of GDNF Ameliorates Neurodegeneration in Parkinson's Disease

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 629 KB

english, 2007

680

529. rAAV Mediated Parkin Over-Expression Partially Ameliorates the Behavioral Effects of the 6-Hydroxy Dopamine Lesion

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 579 KB

english, 2007

681

531. Cell Targeting in the CNS Using HIV-1-Based Lentiviral Vectors Bearing Alternative Glycoproteins and Promoters

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 604 KB

english, 2007

682

532. Trans-Synaptic Neurotoxicity of HIV-1 gp120 and Trans-Synaptic Protection Using rSV40 Vectors Delivery Antioxidant Enzymes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 604 KB

english, 2007

683

533. AAV-Mediated Aipl1 Gene Replacement in a Mouse Model of Leber Congenital Amaurosis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

684

534. Improvement of Parkinson's Disease and Increase Action of Astrocytes by Human HGF

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 609 KB

english, 2007

685

535. Axonal Regeneration of Retinal Ganglion Neurons Using Immortalized Adult Human Olfactory Ensheathing Glia

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 609 KB

english, 2007

686

536. Activation of the JNK Pathway in a Rat Model of HD and Implication in the Pathology

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 609 KB

english, 2007

687

537. Human Studies as Basic Investigations: Patterns of Citation for Gene Transfer Phase I Clinical Trials in Malignant Glioma

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 581 KB

english, 2007

688

538. IFN-γ Secretion Is Polarized at Effector Immunological Synapses (IS) in Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 581 KB

english, 2007

689

539. Investigating the Role of MCP-1 in Early Alzheimer's Disease Via rAAV-Mediated Hippocampal Gene Transfer in a Triple Transgenic Mouse Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2007

690

540. Gene Therapy Approach for Transthyretin Amyloidosis Using a Lentiviral Vector Expressing the Transsuppressor Variant

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 602 KB

english, 2007

691

541. Induced Collateral Circulation by Hypoxia-Inducible Factor-1α Decreased Cerebral Infarction in Rat

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 602 KB

english, 2007

692

542. Non-Viral Gene Therapy Technology in the Treatment of Chronic Pain

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 602 KB

english, 2007

693

543. Role of Anti-Oxidant Enzymes Delivered Using Recombinant SV40-Derived Vectors in Protecting from Tat-Mediated Neurotoxicity In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

694

544. Constitutive GABA Expression Via a Recombinant Adeno-Associated Virus Consistently Attenuates Neuropathic Pain

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 616 KB

english, 2007

695

545. Attenuation of Functional Deficits in the QA Model of Huntington's Disease Following AAV Therapeutic Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 616 KB

english, 2007

696

546. A New Ex-Vivo Approach Using Autologous Dermal Fibroblasts Expressing hLMP3 Induces Bone Formation and Bone Healing in Animal Models

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 472 KB

english, 2007

697

547. Bone Regeneration at the Site of Osteoporotic Bone Fracture with Xenogeneic Skeletal Muscle Cells Producing BMP-2

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 472 KB

english, 2007

698

548. Mesenchymal Stem Cells Transduced Ex Vivo with BMP2 Reduce the Bone Consolidation Period in a Canine Model of Mandibular Bone Distraction

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 596 KB

english, 2007

699

550. Combination of Baculovirus-Mediated BMP-2 Expression and Rotating-Shaft Bioreactor for Cartilage Tissue Engineering

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2007

700

551. Single Clone Selection of TGF-β1 Expressing Chondrocytes Using Retroviral Vector for the Treatment of Cartilage Defects: Its Stability, Efficacy and Safety

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 569 KB

english, 2007

701

552. Active Immunization Against Macrophage Migration Inhibitory Factor Using a Novel DNA Vaccine Prevents Inflammation and Destruction in Murine Models of Arthritis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2007

702

554. Human Vascular Endothelial Growth Factor Gene Transference in an Unipedicle TRAM Flap by Electroporation To Prevent Necrosis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2007

703

555. Viral Mediated Transfer of the ELOVL4 Gene Can Result in High Level ELOVL4 Protein Expression in Human RPE Cells, Increasing the Major Anti-Inflammatory Retinal Fatty Acid DHA

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 551 KB

english, 2007

704

556. Fetal AAV-Mediated Intra-Thoracic Gene Transfer and 3D Reconstruction of Bioluminescent Images of Infant Rhesus Monkeys Expressing Firefly Luciferase

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 551 KB

english, 2007

705

557. Survival of the Fittest: Challenging Lentiviral Vector-Transduced Cells with HIV-1 Replication

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

706

558. Chimeric Human and Rhesus TRIM5α Expressed Via Lentiviral Vectors Potently Restrict HIV-1 Infection In Vitro in CD34 Cell Derived Macrophages and In Vivo in SCID-hu Derived T Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

707

559. Gene Silencing Using SV(siRNA-CCR3) and Delivery of SV(SFv-CCR3) in CNS Protects Brain Microglia from Infection of Primary HIV Isolates

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

708

560. Effectiveness of Combinatorial Gene Therapy in Protecting PBMC from HIV-1 Infection

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 651 KB

english, 2007

709

561. Simultaneous Expansion of CMV and EBV Specific T Cells Using Chimeric CMVpp65: EBNA3C Transgene Expressing Peripheral Blood Antigen Presenting Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

710

562. Foamy Anti-HIV Vectors with MGMT Selection Cassettes To Evaluate AIDS Gene Therapy Strategies in the Macaque SHIV Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 609 KB

english, 2007

711

563. In Vivo Derivation of HIV-1 Resistant Transgenic T Cells by Lentiviral Vector Transduction of a Triple Combination of Anti-HIV Genes Anti-CCR5 Ribozyme, Tat-Rev siRNA and a TAR Decoy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 609 KB

english, 2007

712

564. A Cationic Peptide Encoded by Influenza Virus A (H5N1) Can Operate as a Protein Carrier In Vitro and In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

713

565. Complex Adenovirus-Mediated Expression of C, PreM, E, and NS1 Proteins of West Nile Virus Induces Both Humoral and Cellular Immune Responses

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 613 KB

english, 2007

714

566. Repeated Exposure to HIV-1 Selects for Highly HIV-Resistant Cells in Gene-Modified, but Not Naive, Lymphocytes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 613 KB

english, 2007

715

567. Effect of Lentivirus Vector-Based shRNA on Chemotherapeutic Inhibition of HIV: Demonstration of Antiviral Synergy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

716

568. Generation of a Hybrid SHIV Carrying HIV-1 Integrase in SIVmac239, as a Means To Test the Effectiveness of Anti-lntegrase Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

717

569. RNAi Targeted to Cellular Genes Involved in the HIV Life Cycle (Cyclins and Cyclin-Dependent Kinases) Results in Inhibition of HIV Replication

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

718

570. Multi-Targeting, Bifunctional Small Interfering RNAs

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 605 KB

english, 2007

719

571. Downregulation of CCR5 and Inhibition of HIV-1 with RNAi, Ribozyme and Single Chain Fv Antibody Delivered by SV40-Derived Vectors To Protect CCR5-Expressing Primary Cells: Monocyte-Derived Macrophages and Microglial Cells from R5-Tropic HIV-1

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 605 KB

english, 2007

720

572. Complete Knockdown of CCR5 by Lentiviral Vector Expressed siRNAs for HIV Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 605 KB

english, 2007

721

573. In Vivo Derivation of CXCR4 siRNA Transgenic Thymocytes in SCID-hu Mice and Inhibition of HIV-1 Infection by Lentiviral Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 645 KB

english, 2007

722

575. Development of Anti-HIV Gene Therapy Strategy Using Novel Endoribonuclease, MazF

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

723

576. Gene Delivery Targeting HIV-1 Integrase Does Not Select for Mutations in the Integrase Gene

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 604 KB

english, 2007

724

578. Optimal Condition for Lentivirus Infection and Effective Reduction of HIV-1 Infectivity by Membrane Bound C-Peptides

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

725

579. Investigating the Relationship between Duration of Antigen Expression and the Magnitude and Phenotype of the CD8+ T Cell Response Elicited by Recombinant Adenovirus

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 631 KB

english, 2007

726

580. Zinc-Finger Nucleases Inactivating Hepatitis B Virus Genomic DNA

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 631 KB

english, 2007

727

581. Intracranial Glioma Tropism of Genetically Modified T Lymphocytes Following CNS Intraparenchymal Adoptive Transfer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

728

582. Genetic Delivery of Avastin, an Anti-VEGF Monoclonal Antibody, Suppresses Human Tumor Growth In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 627 KB

english, 2007

729

583. Utilization of a Novel Luciferase Construct To Demonstrate Trafficking of Genetically Targeted CD19 Specific T Cells to Systemic Human Acute Lymphoblastic Leukemia in a Mouse

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 627 KB

english, 2007

730

585. In Vivo Activation of Endogenous, Pigment Epithelial Derived Factor (PEDF) Expression by a Zinc Finger Transcription Factor in Human Lung Cancer Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

731

587. Redirecting Specificity of Lymphocytes to CD19+ Malignancies Using Non-Integrating Gene Transfer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

732

588. Anticancer Activity of Oncolytic Adenovirus Vector Armed with IFN-alpha and ADP Is Enhanced by Pharmacologically-Controlled Expression of TRAIL

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 644 KB

english, 2007

733

589. Generation of a New Type of Yeast-Secreted Biotinylated Recombinant Antibodies Directed Against Mesothelin and Able To Prevent CA 125/Mesothelin-Dependent Cell Attachment

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 644 KB

english, 2007

734

590. Antitumor Effect of Intravenous Administration of Oncolytic Herpes Simplex Virus Expressing Interleukin 12 on Systemic Metastases

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

735

591. Combination Treatment Strategies That Modify Ceramide Metabolism To Increase the Efficacy of FasL Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 646 KB

english, 2007

736

592. In Vivo Monitoring of Efficacy of Human Genetically Modified PSMA-Specific Lymphocytes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

737

596. Imaging of HSV1-tk Expressing Cytolytic T Cell Clones in Glioma Patients with [18F]FHBG Positron Emission Tomography

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 594 KB

english, 2007

738

597. Expression of Biologically Active Anti-HER2 Antibody from an AAV Gene Transfer Vector

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 593 KB

english, 2007

739

598. Targeted Elimination of Stem-Like Glioma Progenitors with Genetically Engineered Cytolytic T Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2007

740

599. A Critical Role for Receptor Dimerisation and Transmembrane Domains for the Optimal Function of Chimeric Immune Receptors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 592 KB

english, 2007

741

601. Switching Adenovirus Fibers for Retaining Gene Delivery Efficacy in the Presence of Neutralizing Antibodies

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

742

602. Combination Therapy with Radiation or Cisplatin Enhances the Potency of Ad5/35 Chimeric Oncolytic Adenovirus in a Preclinical Model of Head and Neck Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

743

603. Chemoprotection of Human Hematopoietic Stem Cells by Lentiviral Transfer of Multidrug-Resistance 1 Gene in Combination with the O6-Methylguanine-DNA Methyltransferase P140K Mutant Gene

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

744

604. A Dual-Action, Armed Replicating Adenovirus for the Treatment of Bone Metastases of Breast Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 646 KB

english, 2007

745

605. Compassionate Approval Process for Experimental Gene Based Products

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

746

606. Delivery of the CD40 Ligand (CD40L, CD154) Transgene by an Oncolytic Adenovirus Construct: A Targeted Therapeutic Approach for Human Multiple Myeloma

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 634 KB

english, 2007

747

607. The Application of Tumor Stem Cells for Adenoviral-Based Glioma Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 634 KB

english, 2007

748

608. Expression of Tissue Inhibitor of Matrix Metalloproteinases (TIMP)-3 by an Oncolytic HSV Enhances Antitumor Efficacy Against Neural Tumors and Tumorspheres

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

749

609. Kringle 1 Domain of Human Hepatocyte Growth Factor (HGFK1) Inhibits the Growth and Metastasis of Hepatocellular Carcinoma in Rats

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 573 KB

english, 2007

750

610. Treatment of Metastatic Colorectal Cancer with Triple Capsid-Modified Adenoviruses Featuring Reduced Liver Tropism

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 573 KB

english, 2007

751

611. Development of a Selective Non-Viral Gene Directed Enzyme/Pro-Drug Cancer Therapy Based on a Chimeric Reactive Oxygen Species-Response Element

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

752

612. Assessment for Antitumor Activity of Telomerase-Specific Oncolytic Virotherapy in the Hypoxic Microenvironment

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 639 KB

english, 2007

753

613. Tight Regulation of lonizing-Radiation Inducible Transgene Expression by Lentivirus Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 638 KB

english, 2007

754

614. Proteomics Analysis in the Development of Molecular Precision Approaches for Cancer Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

755

615. Short Hairpin RNA-Expressing Oncolytic Adenovirus-Mediated Inhibition of IL-8: Effects on Anti-Angiogenesis and Tumor Growth Inhibition

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 604 KB

english, 2007

756

616. Salmonella choleraesuis as an Anticancer Agent in a Syngeneic Model of Orthotopic Hepatocellular Carcinoma

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 603 KB

english, 2007

757

618. A Novel Chromogranin-A Promoter-Driven Oncolytic Adenovirus for Midgut Carcinoid Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 502 KB

english, 2007

758

619. Ad5/19p for Targeting of Renal Cancer and Detargeting the Liver

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 502 KB

english, 2007

759

621. Fluorescently Tagged Conditionally Replicative Adenovirus Via Modification with Protein IX Red Fluorescent Protein Fusion

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 547 KB

english, 2007

760

622. Fiber Region-Modified Adenoviruses Produced Anti-Tumor Effects to CAR-Low Expressing Tumors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 547 KB

english, 2007

761

624. Adenovirus Delivered to Tumor Endothelium by Angio-Adenobodies

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

762

626. Suppression of Renal Cell Carcinoma Growth and Metastasis with Adenoviral Delivery of Chimeric Antiangiogenic Proteins

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 626 KB

english, 2007

763

628. Prevention of Irradiation-Induced Salivary Hypofunction by Microvessel Protection in Mouse Salivary Glands

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 566 KB

english, 2007

764

629. An Adenovirus Vector Re-Targeted to Her2/neu by an Affibody™ Molecule and De-Targeted from CAR, av Integrin and HSG Binding: In Vitro and In Vivo Data

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 566 KB

english, 2007

765

631. Therapeutic Efficacy of Midkine Promoter-Based Conditionally Replicative Adenovirus Vector for Targeting the Midkine-Expressing Human Bladder Cancer Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 628 KB

english, 2007

766

632. Improving Cancer Gene Therapy for Advanced Head and Neck Cancer with a Multi-Modal Therapy Approach

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 628 KB

english, 2007

767

633. Lentiviral-Mediated Gene Delivery of IFN-beta Strongly Inhibits Pancreatic Cancer-Derived Cells Proliferation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 625 KB

english, 2007

768

634. MDR1 Gene Transfer Using a Lentiviral SIN Vector Confers Radioprotection to Human CD34+ Haematopoietic Progenitor Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 625 KB

english, 2007

769

636. Development of Prostate-Specific Conditional Replication-Competent Adenovirus for Prostate Cancer Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 627 KB

english, 2007

770

637. Targeted Cancer Gene Therapy Using AAV2-Mediated Anti-Angiogenesis Approaches

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 627 KB

english, 2007

771

639. Irradiation Prior to Adenovirus Treatment Increases Transgene Expression in Prostate and Breast Cancer Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 624 KB

english, 2007

772

640. Evaluation of Biodistribution and Safety of DWP418, Relaxin Expressing Oncolytic Adenovirus Therapeutics

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 624 KB

english, 2007

773

641. Triple Helix-Forming Oligonucleotides Specifically Reduces ATM Transcription, Translation, and Radiosensitivity in Human Glioma Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 624 KB

english, 2007

774

642. Regio-Specific Mutagenesis of Thermostabilized Yeast Cytosine Deaminase for Improved 5-Fluorocytosine Activity

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 617 KB

english, 2007

775

644. Whither Therapeutic Targeting? The Sorcerer's Apprentice Finally Meets Jasper Johns*

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 617 KB

english, 2007

776

645. Friend Murine Erythroleukemia (MEL) Cells Do Not Reliably Predict Levels of Globin Transgene Expression In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 604 KB

english, 2007

777

646. Restoration of von Willebrand Factor Function in a Murine Model of Severe von Willebrand Disease after Liver Specific Gene Transfer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 604 KB

english, 2007

778

647. Gene Therapy of MPL Deficiency: A Paradigm for Gene Addition Therapy of Growth Factor Receptors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

779

649. Generation of Efficient Human Blood Progenitor-Targeted Recombinant Adeno-Associated Viral Vectors by Applying an AAV Random Peptide Library on Primary Human Hematopoietic Progenitor Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

780

650. In Vivo Selection of Hematopoietic Cells Following Retroviral Gene Transfer in a Dog with Mucopolysaccharidosis VII

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 615 KB

english, 2007

781

652. Cytidine Deaminase Gene Transfer Allows Transient In Vivo Enrichment of Transduced Hematopoiesis by Extended Low Dose Cytarabine Treatment

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 593 KB

english, 2007

782

653. Efficient Transduction of Thalassemic CD34+ Cells by Novel y-Globin Gene Lentiviral Insulated Vectors with the HPFH-2 Enhancer and the -117 HPFH Promoter Mutation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 593 KB

english, 2007

783

654. Construction of Foamy Virus Vectors for the Genetic Correction of beta-Thalassemia

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2007

784

655. Segmental Trans-Splicing of the C57BI/6 Murine von Willebrand Factor Pre-mRNA To Facilitate Packaging into Gene Transfer Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 617 KB

english, 2007

785

656. Lentiviral Vector-Mediated Correction of Artemis Deficient SCID and Functional Protein Analysis by FRET

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 617 KB

english, 2007

786

657. Construction of a High Performance Lentiviral cDNA Library Derived from Human Fetal Liver

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 613 KB

english, 2007

787

658. The Erythrocyte Immunity Research on Chronic Venous Insufficiency of Lower Limb

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 613 KB

english, 2007

788

660. Adenovirus Induced Innate Immune Responses Are Mediated in Part by the Presence of Natural Antibodies in Ad Naïve Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 655 KB

english, 2007

789

661. Dose-Limiting Toxicities Following Systemic Administration of Non-Human Primate Derived Adenoviral Vectors to Cynomolgus Macaques

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 655 KB

english, 2007

790

662. Study of Adenovirus Vector-Induced Activation of Muscle Dendritic Cells and Analysis of Mouse Dendritic Cell Migration from the Tibialis Anterior Muscle

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 590 KB

english, 2007

791

663. Methotrexate Selection of Gene Modified T Cells with an Engineered Human Dihydrofolate Reductase (DHFR)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 590 KB

english, 2007

792

666. Effect of Anti-Adenoviral Immunity on Long-Term Vector and Islet Graft Function

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2007

793

667. Periocular Triamcinolone Enhances Intraocular Gene Expression Following Delivery by Adenovirus

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 581 KB

english, 2007

794

668. Effect of Pre-Existing Anti-Adenovirus Immunity and Anti-Tumor Immunity on the Efficacy of Adenovirus Vectors in Immunocompetent Syrian Hamster Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 581 KB

english, 2007

795

669. Involvement of MyD88 and TLR9 in the Innate Immune Response Elicited by Replication-Incompetent Adenovirus Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

796

670. Administration of a Combination of a Nondepleting CD4 Antibody and Cyclosporine Is Efficient at Attenuating Humoral but Not Cellular Immunity after Adenovirus Serotype 5 Mediated Gene Transfer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 627 KB

english, 2007

797

671. Directing a Transgenic Erythropoietin Fusion Protein into the Regulated Secretory Pathway in Murine and Rat Salivary Gland

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 627 KB

english, 2007

798

672. Efficient Conversion of Embryonic Stem Cells into Myogenic Lineage Using an Inducible Gene Expression System

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 553 KB

english, 2007

799

674. Hypoxia-Regulated and Cell-Specific AAV Vectors Targeting the Retina and Retinal Pigmented Epithelium

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 553 KB

english, 2007

800

675. Enhanced Factor VIII Secretion in Hemophilia A Mice Using a Feline Immunodeficiency Virus Vector and Transgenic Modifications

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 585 KB

english, 2007

801

676. Direct Comparison of Hepatocyte-Specific Expression Cassettes after Adenoviral Transfer and Hydrodynamic Transfer of Plasmids and Minicircles in C57BL/6 Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 585 KB

english, 2007

802

677. AAV-Mediated IGF-1 Delivery to the Cervical Spinal Cord of the SOD1 Rat Model of ALS Via Intraparenchymal Injection

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 581 KB

english, 2007

803

678. Cell Permeable, Anti-Inflammatory Peptides Targeting NF-kB and NFAT Pathways Prevent the Onset of Diabetes in NOD Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 581 KB

english, 2007

804

681. Improvement of Survival of Skin Flaps by Combined Gene Transfer of Hepatocyte Growth Factor and Prostacyclin Synthase

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 639 KB

english, 2007

805

683. Regulated Gene Expression in Human Hematopoietic Stem Cells after Transduction with Helper-Dependent Ad5/35 Vector

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 597 KB

english, 2007

806

684. Expression of Foxp3 in a Subset of Rat Dendritic Cells (DCs), Plasmacytoid DC, Generated from a Long-Term Culture of Bone Marrow Cells (BMC) Driven by FLt3-Ligand and IL-6

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 597 KB

english, 2007

807

685. The Role of PTEN Tumor Suppressor Gene in Prostate Cancer Derived by Prostate Specific Deletion of PTEN

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 639 KB

english, 2007

808

686. Establishment of a Murine Colorectal Tumor Model for In Vivo Imaging and Development of Gene Therapies for Metastatic Disease

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 639 KB

english, 2007

809

687. A Novel Patient-Specific Cancer Vaccine Approach Based on Genetically Altered Tumor Immune Profile and Xenograft Tumor Expansion

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

810

689. Targeting Activator Protein-1 To Investigate Protective Phytocompounds Against UVB Radiation-Induced Photoaging in Mouse

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 585 KB

english, 2007

811

691. Developmental Stage Determines Distribution of Organ Transduction after Extracoelomic Cavity Injection of Lentiviral Vector

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 527 KB

english, 2007

812

692. Regulatory Elements for Improved Gene Therapy Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2007

813

693. Adverse shRNA Cytotoxicity Can Accelerate Tumorigenesis in Genetically Predisposed Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

814

694. RNA Interference Mediated by Cardiotropic AAV Vectors To Inhibit Coxsackievirus B3 Infections in Cardiac Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

815

695. In Vitro and In Vivo Evaluation of shRNAs and miRNA Shuttles for Therapeutic RNAi

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

816

696. Efficient Knock-Down of Prion Protein by Lentivectors Expressing Short Hairpin RNAs

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

817

697. Therapeutic Gene Knockdown with Wrapped Liposome-Mediated Systemic siRNA Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

818

698. Mutation-Independent RNAi for Rhodopsin-Linked Autosomal Dominant Retinitis Pigmentosa

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

819

699. Allele-Specific Silencing of Mutant Huntingtin for Huntington's Disease Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

820

700. Development of RNA Aptamers for Human Toll-Like Receptor 2

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

821

701. Restoration of Dystrophin Expression in the Diaphragm of the Dystrophic mdx Mice by Polymer-Tagged Morpholino Antisense Oligonucleotides

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

822

703. Restoration of Proper Splicing of the β-Globin Gene Using Triplex-Forming Oligonucleotides

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 645 KB

english, 2007

823

704. Efficient Organ Selective Non-Viral siRNA Delivery System Modified with a Newly Identified Peptide Sequence

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

824

706. Signal-Smart 1 (SS1) Oncolytic Herpes Virus: The First Transcriptionally Targeted Mutant Herpes Virus Designed Against Pro-Oncogenic Signaling Pathways

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 629 KB

english, 2007

825

707. Inhibiting HIV-1 Gene Expression and Replication with Expressed Long Hairpin RNAs

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

826

708. Efficient Delivery and Improved Gene Targeting of PNA-Peptide Conjugates in a Transgenic Mouse Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 589 KB

english, 2007

827

709. Progress on Mutation Independent Silencing of Rhodopsin Using RNA Interference (RNAi) and Trans Complementation by an RNAi-Resistant Rhodopsin Transgene

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 589 KB

english, 2007

828

710. Argonaute2 (Ago2) Gene Silencing by Liposomal Transfection with siRNA for Ago2 Induces Apoptosis on HT1080 Cells and HUVECs

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2007

829

711. In Vivo RNA Silencing of the Mcl-1 Gene Confers Increased Susceptibility of Melanoma Cells to Apoptosis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 594 KB

english, 2007

830

712. Gene Editing Mediated by a Novel DNA Analogue Called INA®

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 594 KB

english, 2007

831

713. Induction of Dystrophin Expression by Exon Skipping in mdx Mice by PNA and PNA-Peptide Conjugates

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 601 KB

english, 2007

832

714. Sequence-Specific Inhibition of RNA Polymerase II- and Ill-Dependent Transcription Using Zorro Locked Nucleic Acid (LNA)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 601 KB

english, 2007

833

715. Sequence-Specific Triple Helix Formation with Genomic DNA

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 601 KB

english, 2007

834

716. Screening of DNAzymes That Inhibit β-Catenin Gene Expression in Colon Cancer Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 588 KB

english, 2007

835

717. Inhibition of Enterovirus 71 in Virus-Infected Mice by RNA Interference

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 588 KB

english, 2007

836

718. Delivery of IL-10 by an AAV Vector to the Lungs of CFTR Knockout Mice Reduces Inflammation upon Chronic Infection with P. aeruginosa

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 588 KB

english, 2007

837

719. Biological Differences in rAAV Transduction of Human and Old World Non-Human Primate Airway Epithelia

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 551 KB

english, 2007

838

720. Evaluating AAV-Mediated Transduction of Primate Liver as a Therapeutic Strategy for Lysosomal Storage Disorders

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 551 KB

english, 2007

839

721. Intravenous Injection Cofactors of Adeno-Associated Virus Produce Varying Tissue-Specific Transduction Levels in Adult Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 630 KB

english, 2007

840

722. Intravascular Delivery of AAV-9 Leads to Efficient Transduction of Multiple Muscles in Dog

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 630 KB

english, 2007

841

723. Novel AAV Variants Result in Unique Patterns of Transduction in Mouse Brain

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

842

724. Convection-Enhanced Delivery (CED) of AAV1-hrGFP into the Monkey Brain Results in Robust Neuronal and Non-Neuronal Transduction of Cortical and Subcortical Regions

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 572 KB

english, 2007

843

725. Site-Specific Labeling of Targeted AAV with Fluorophores Using Biotin Ligase Allows Comparison of Cellular Binding and Intercellular Trafficking Pathways Used by Modified an Un-Modified Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 572 KB

english, 2007

844

726. Evaluation of Recombinant Mouse Adenovirus Type 1 (MAV-1) Vectors in Tumor Bearing, Immune Competent Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 534 KB

english, 2007

845

727. Administration of an Osteosarcoma-Targeted Canine Oncolytic Adenovirus in Normal and Tumor-Affected Dogs

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 534 KB

english, 2007

846

728. Phase I Study of Intratumoral (IT) Injection with a Telomerase Specific Conditionally Replicative Adenovirus (CRAd), Telomelysin(OBP-301), in Patients with Advanced Solid Tumor

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 605 KB

english, 2007

847

729. Long-Term Results of a Phase l/ll Study of Ad-OC-TK/VAL Gene Therapy for the Patients with Metastatic or Local Recurrent Prostate Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 605 KB

english, 2007

848

730. Ad16 and CV23 Adenoviruses Are Superior to Adenovirus 5 for Transduction of Human Low-Passage Glioma Cells and Cancer Stem Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2007

849

731. Carrier Cell-Mediated Delivery of a Replication-Selective Oncolytic Adenovirus for Ovarian Cancer Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 533 KB

english, 2007

850

732. Development of Novel Hybrid Adeno-Semliki Forest Viral Vectors for Anti-Cancer Applications

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 533 KB

english, 2007

851

733. Comparative Evaluation of oncolytic Adenoviruses for Selective Eradication of oral Cancer and Precancerous Lesions

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2007

852

734. Quantitative Analysis of Intracellular Unpacking of Polymeric DNA Nanoparticles Constructed from Quantum Dot-FRET

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 553 KB

english, 2007

853

735. Design of Peptide Vinyl Ester Inhibitors of the Proteasome To Increase Gene Transfer Efficiency

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2007

854

736. Glycopolyamines for NF-kappa B Decoy Delivery to Cardiomyocytes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 625 KB

english, 2007

855

738. Targeted Delivery of Therapeutic Nucleic Acids to Breast and Pancreatic Cancer Tumors Using Multifunctional Nanoparticles with Activity Modulated by Redox Potential Gradients

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2007

856

739. A Novel Peptide Discovered by Intracellular Bacteriophage Display Mediates Nuclear Targeting

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 540 KB

english, 2007

857

740. Chromatin Reconstitued with Engineered Histones as an Efficient Gene Delivery Agent

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 540 KB

english, 2007

858

741. Chemical Modification of Oligonucleotides and DNA To Enable the Engineering of Improved Gene Therapy Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 507 KB

english, 2007

859

742. Intracerebral AAV5-Mediated Gene Transfer in Metachromatic Leukodystrophy: Preclinical Evaluation of Efficiency and Tolerance in Large Animal

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 507 KB

english, 2007

860

743. Dose Response of Subretinal AAV2 and AAV8 GFP Gene Transfer to the Macaque Macula: Favorable Safety Profile but Risk of Focal Immunotoxicity at the Highest Dose

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 562 KB

english, 2007

861

744. In Vivo Engineering of Light Sensitive Neurons in the Diseased Retina

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 562 KB

english, 2007

862

745. Reversal of Visual Deficits in Animal Models of Leber Congenital Amaurosis within Weeks after Treatment with an Optimized Adeno-Associated Virus (AAV)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 626 KB

english, 2007

863

746. AAV-Mediated Gene Therapy of Albinism

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 625 KB

english, 2007

864

747. Systemic Insulin-Like Growth Factor-1 (IGF-1) Therapy Reverses Hyposensitivity in a Mouse Model of Diabetic Peripheral Neuropathy (DPN)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

865

748. Impact of Age of Treatment on AAVrh.10hCLN2-Mediated Amelioration of Symptoms in CLN2 Knockout Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 592 KB

english, 2007

866

749. SMA Based Therapeutic Trans-Splicing RNAs Repair SMN1 Deficiency

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 592 KB

english, 2007

867

750. A Vectored Measles Vaccine Induces Hepatitis B Surface Antigen Antibodies While Protecting Macaques Against Measles Challenge

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 437 KB

english, 2007

868

751. 4-1BB Antibody Agonist Significantly Enhances SIV-Specific CD8+ T-Cell Immunity and Proliferation Following Naked DNA Vaccination in Cynomolgus Macaques

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 437 KB

english, 2007

869

752. Comparison of the Efficacy of a Six Genetic Anti-Plaque Vaccine Candidates Against a Lethal Respiratory Tract Challenge with Yersinia pestis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 569 KB

english, 2007

870

753. Single Administration of an Adenovirus Vectored Molecular Vaccine Provides Fast-Acting Protection Against Foot-and-Mouth Disease Virus in Cattle

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 569 KB

english, 2007

871

754. Enhanced Immunogenicity to HIV Plasmid Vaccines in Non-Human Primates Using an IL-12 Expressing Plasmid and Constant-Current Electroporation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 631 KB

english, 2007

872

755. Induction of Both Rapid and Persistent Passive Immunity Against Anthrax Toxin by Co-Administration of Adenovirus and Adeno-Associated Virus Type rh.10 Vectors Expressing Anti-Protective Antigen Antibody

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 631 KB

english, 2007

873

756. Vaccination with Linear Expression Cassettes Protects Mice Against Lethal Influenza A Challenge

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

874

757. Generation of Protective Immunity Against 1918 (H1N1) and Divergent Isolates of Avian Influenza (H5N1) Viruses through Different Vaccination Strategies

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 592 KB

english, 2007

875

758. Adenoviral-Mediated Delivery of Pseudomonas Exotoxin (PE) Fused to IL-13 Induces Regression of Intracranial Human Glioblastoma Xenografts in Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 592 KB

english, 2007

876

759. Lymphoma Chemovirotherapy: CD20-Targeted and Convertase-Armed Measles Virus Enhances Fludarabine Efficacy Locally

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 613 KB

english, 2007

877

760. Effects of Stable Endostatin and Angiostatin Gene Therapy on Angiogenesis-Related Gene Expression in Multistage Prostate Cancer in TRAMP Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 613 KB

english, 2007

878

761. Retroviral Vector-Producing Mesenchymal Stem Cells for Tumor Tracking and Therapeutic Gene Amplification as Systemic Suicide Cancer Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

879

762. Transcriptional Targeting Achieves Effective Control of Systemic Dissemination by Replication-Competent Retrovirus

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 626 KB

english, 2007

880

763. Mutual Sensitization with Telomerase-Specific Oncolytic Virotherapy and Ionizing Radiation in Cytotoxic Activity Against Human Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 626 KB

english, 2007

881

764. Enhancing the Therapeutic Index of Oncolytic CVA21

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

882

765. Nature of Seneca Valley Virus (SW-001/NTX-010) RNA in Blood after Systemic Delivery to Patients with Solid Tumors Expressing Neuroendocrine Features

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 627 KB

english, 2007

883

766. Exploring the Influence of Retroviral Integration Site Selection on Gene Expression in ADA-SCID Patients Treated with Stem Cell Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

884

767. Therapeutic Expression of a Platelet-Specific Integrin Restores Hemostasis in Dogs with Glanzmann Thrombasthenia

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 613 KB

english, 2007

885

768. Transplantation of Genetically Modified Cells for Treatment of Infection in Patients with X-Linked Chronic Granulomatous Disease (X-CGD)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 613 KB

english, 2007

886

769. Correction of Canine XSCID by Gene Therapy Using Preclinical SIV Lentiviral Vectors Expressing Human or Canine Gamma Chain

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 566 KB

english, 2007

887

770. Self-Inactivating Retroviral Vectors Expressing hIL2RG from an Internal SFFV Enhancer-Promoter Induce Leukemia by Insertional Mutagenesis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 566 KB

english, 2007

888

771. Successful Gene Therapy of Canine Leukocyte Adhesion Deficiency Using Foamy Viral Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 633 KB

english, 2007

889

772. Efficient Transduction of Macaque Hematopoietic Repopulating Cells with HIV-Derived Lentiviral Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 633 KB

english, 2007

890

773. Clinically Relevant Levels of Hematopoietic Stem Cell Gene Transfer in Rhesus Macaques Nearly Four Years Following Transplantation with Autologous Hematopoietic Cells Transduced with an Simian Immunodeficiency Virus-Based Lentiviral Vector

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

891

775. The Woodchuck Hepatitis Virus Post-Transcriptional Regulatory Element Reduces Readthrough Transcription from Retroviral Vectors To Improve Vector Titers and Expression

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

892

776. An Engineered Zinc Finger Protein Transcriptional Activator of Pigment Epithelium-Derived Factor Drives Long-Term Inhibition of Choroidal Neovascularization

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 616 KB

english, 2007

893

777. Targeted Gene Addition into a Putative Safe-Harbor Locus in the Human Genome Using Engineered Zinc Finger Nucleases Russell C. DeKelver, Erica A. Moehle, Jeffrey C. Miller, Jeremy M. Rock, David E. Paschon, Igor Rupniewski, Phillip Y. Tam, Edward J. Rebar, Michael C. Holmes, Philip D. Gregory, Fyodor D. Urnov.

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 616 KB

english, 2007

894

778. Identification of Additional Barrier and Protein Binding Activities in Extended Core Sequences of the cHS4 Chromatin Insulator

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2007

895

779. Gaussia Luciferase for Monitoring of Tumor Growth and Therapy in Culture and In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 557 KB

english, 2007

896

780. Controlling T-Cell Proliferation and Survival with Synthetic, Small Molecule-Controlled RNA-Based Regulatory Systems

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 557 KB

english, 2007

897

781. The DNA-Binding Specificity of Designer Zinc Finger Nucleases Is a Major Determinant of Activity and Genotoxicity in Human Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 611 KB

english, 2007

898

782. Characterizing the Molecular Mechanism for Robust, Sustained Hepatic Expression from Episomal Lentiviral Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 611 KB

english, 2007

899

783. Systemic Comparison of Promoters Driving Transgene Expression in Airway Epithelia Using a Non-Primate Lentiviral Vector

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

900

784. Differential Regulation of Interferon Alpha-Responsive Antiviral Pathways Determines Tumor Selectivity of Newcastle Disease Virus

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 615 KB

english, 2007

901

785. Lentiviral Protein Transduction and Intracellular PIC Visualization by Vector Incorporated HIV-1 Integrase Fusion Proteins

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 615 KB

english, 2007

902

786. Optimizing Systemic Delivery of Oncolytic Measles Virus by Using Virus Infected Cell Carriers

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

903

788. Development of Analytical Tools in Downstream Processing of Influenza Virus

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 613 KB

english, 2007

904

790. Transduction of Primary Human Monocytes/Macrophages Using HIV-1-Derived Vector Particles Is Enhanced by the Viral Protein VpxPBj Provided by SIVsm PBj-Derived Vector Like-Particles

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 614 KB

english, 2007

905

791. Macrophage Differentiation from Human CD34 Cells in order To Test Anti-HIV Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 614 KB

english, 2007

906

792. Biodistribution and Tumor Infectivity of Semliki Forest Virus Vectors in Mice: Effects of Readministration

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

907

793. Integration-Defective Lentiviral Vectors as a Platform for Sleeping Beauty Transposase-Mediated Gene Insertion

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 627 KB

english, 2007

908

794. Development of Novel Defective Sendai Virus Vectors Capable of Expressing Therapeutic Genes Persistently without Chromosomal Integration

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 627 KB

english, 2007

909

796. In Vitro Evolution of a Replicating, Chimeric Murine Leukemia Virus-Gibbon Ape Leukemia Virus Vector

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 597 KB

english, 2007

910

797. Regulated HIV-1 and HIV-2 Lentiviral Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 597 KB

english, 2007

911

798. Expression of Transduced Proteinase Inhibitor 9 Is Upregulated in Human Islets Exposed to Pro-Apoptotic Stimuli; Implications for Protection of Transplanted Islets

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

912

799. Optimizing a Protocol for Transduction of Nonhuman Primate ES Cells with Lentiviral Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 645 KB

english, 2007

913

800. MGMTP140K Allows for Efficient and Sustained In Vivo Selection in Baboons and Macaques

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

914

801. Hepatic Expression of MGMTP140K Enables Selection in Primary Hepatocytes: Implication in Gene Therapy for MPS Type I in Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 615 KB

english, 2007

915

802. Lenti-Vector Optimization for IDUA Expression in the Murine Model of Hurler Syndrome (Mucopolysaccharidosis Type I)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 615 KB

english, 2007

916

804. Targeting of Lentiviral Vectors by Magnetic Nanoparticles

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 625 KB

english, 2007

917

805. Retroviral Particle Mediated mRNA Transfer: New Insights into Underlying Mechanisms

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

918

806. Psuedotyping Lentiviral Vector Particles for the Envelope Protein from Feline Leukemia Virus Type C (FLVC)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

919

807. Engineering the Tropism of VSVG-Pseudotyped Retroviral and Lentiviral Vectors Via the Insertion of RGD Targeting Peptides

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

920

808. The Two Phases of Measles Virus Cell Entry through SLAM: Hemagglutinin Residues Necessary for Primary Binding or Membrane Fusion

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

921

809. Two Viruses: Similar Fibers, Similar Receptors, Different Destinies

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 613 KB

english, 2007

922

810. Increasing Incorporation of HN Enhances Infectivity of HPIV3-Pseudotyped Lentiviruses

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 613 KB

english, 2007

923

811. Titers of HIV-Based Vectors Encoding shRNAs Are Reduced by a Dicer-Dependent Mechanism

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 613 KB

english, 2007

924

812. Composition of Purified Lentiviral Vector Products Intended for Gene Therapy: Implications for Quality Control of Vector Production

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 570 KB

english, 2007

925

813. Cell Entry Targeting of Lentiviral Vectors through Pseudotyping with the Measles Virus H and F Proteins

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 570 KB

english, 2007

926

814. The Thermo-Sensitivity of the Reverse Transcription Process Is a Mechanism of MLV-Based Vectors Inactivation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2007

927

815. Abstract Withdrawn

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 622 KB

english, 2007

928

816. Improved Production Protocols for HIV-1-Based Lentiviral Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 622 KB

english, 2007

929

817. A Quantitative Kinetic Analysis of Centrifugation-Based Delivery of Retroviral Vectors into Mammalian Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 622 KB

english, 2007

930

818. Development of Scaleable Retroviral Transduction Strategies Utilizing Whole Cell Lysate and Acoustic Technology

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

931

819. Evaluation of Hybrid Adeno-Associated Virus (AAV) Vectors for Transduction of Cells with Primary Cilia: Applications for Retinal, Cochlear, and Renal Disease

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

932

820. Evaluation of an Adenoassociated Viral Vector Construct Containing the First 26 Amino Acids of CFTR but Missing the First 4 Loops of TMD1

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

933

821. The AAV9 Capsid Preferentially Transduces Cardiac Tissue and Demonstrates Unique Behavior In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 631 KB

english, 2007

934

823. In Vitro Identification of Optimal Exon-Skip Targets for Treatment of Duchenne Muscular Dystrophy Using a Human Muscle Cell Line

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

935

824. Significantly Extended Survival and Improved Behaviore of MPS IIIB Mice by an Intracisternal Delivery of rAAV2 Vector

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 617 KB

english, 2007

936

825. Gene Delivery to Intestinal Epithelial Cells In Vitro and In Vivo with Recombinant Adeno-Associated Virus Types 1, 2 and 5

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 617 KB

english, 2007

937

826. Novel AAV Serotypes Result in Efficient Photoreceptor Transduction

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 617 KB

english, 2007

938

827. Secretion of IL-10 from Recombinant Skin Generated by AAV2/IL-10 Transduction

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

939

828. Gene Transfer of Superoxide-Dismutase Genes and Catalase Confers Radioprotection on Normal Human Primary Lung Fibroblasts and Lymphoblastoid Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 657 KB

english, 2007

940

829. Adeno-Associated Virus-Mediated Gene Transfer: The Combined Use of Self-Complementary AAV Vectors and the Parvovirus B19 Promoter Leads to Expression of Therapeutic Levels of the Human Beta-Globin Gene

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2007

941

830. Gene Transfer to Murine Substantia Nigra Using Adeno-Associated Viral Vectors Pseudo-Typed with Capsids from Serotypes 7 and 9

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 624 KB

english, 2007

942

831. AAV Serotype/Genome Comparison for Gene Therapy Targeting the Liver

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 624 KB

english, 2007

943

832. The IL-2 and IL-12 Genes Favor Paracrine over Autocrine-Targeted AAV2 Gene Delivery in the Generation of Cytotoxic T Lymphocytes, in Fact AAV/IL-2 Autocrine Delivery Is Strongly Inhibitory

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

944

833. Efficient Whole Body Muscle Transduction with Self-Complementary AAV 9 Vectors Following Systemic Delivery in Adult Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 589 KB

english, 2007

945

834. AAV8 Vectors Transduce Oligodendrocytes Efficiently

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 589 KB

english, 2007

946

835. Self-Complementary Adeno-Associated Virus Serotypes Can Induce Efficient Long-Term Therapeutic Effects in Human Cancer Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

947

837. Long-Term Effect and Biosafety of Recombinant AAV-Rat Cygb Expression

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 628 KB

english, 2007

948

838. AAV2 Capsid Specific CTLs Do Not Eliminate AAV Vector Transduced Cells In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

949

841. Gender as a Factor for Gene Transfer to Rodent Salivary Glands

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 615 KB

english, 2007

950

842. Gene Correction by Different Repair Substrates

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 615 KB

english, 2007

951

843. Interaction of Host and Vector-Dependent Factors in Determining the Risk of Germline Transmission of AAV Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

952

844. Differential Immune Responses to Transgene Products from rAAV1 and rAAV8 Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 617 KB

english, 2007

953

845. Characterization of a Bipartite rAAV Vector for Site Specific Integration

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 617 KB

english, 2007

954

846. Strategies for Improving Adeno-Associated Virus Vector-Mediated Gene Transfer in Primary Murine Hematopoietic Stem Cells In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

955

847. Differential Uptake and Nuclear Uncoating of Adeno-Associated Virus (AAV) Vectors as Determinats of Transduction in Cells of Cardiac Origin

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 586 KB

english, 2007

956

848. Hybrid Adeno-Associated Virus Bearing Nonhomologous Inverted Terminal Repeats Enhances Dual-Vector Reconstruction of Minigenes In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 586 KB

english, 2007

957

849. Increased Complexity of Wild-Type AAV-Chromosomal Junctions as Measured by Analysis of Whole Unselected Cellular Genomes: Implications for New Vector Design

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

958

850. Effect of Animal Age and the Route of Administration on Systemic AAV-9 Transduction

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 614 KB

english, 2007

959

852. AAV Rep78 Interacts with the E1 Helper Protein of HPV and Enhances Its ATPase Activity

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

960

854. Evaluation of Hybrid Adeno Associated Virus (AAV)-Mediated Transduction of the Fetal Retina: Impact of Single Amino Acid Changes of the Capsid

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 597 KB

english, 2007

961

855. Optimization of Delivery and Expression of the Pyruvate Dehydrogenase E1 Alpha Subunit Gene Using Self-Complementary Adeno-Associated Virus Serotype Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

962

856. Measuring Clearance of Adenovirus Vectors from the Circulation by Kupffer Cells: Inhibition by Polyanions

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 623 KB

english, 2007

963

857. The Effect of Coagulation Factors on Ad19p Fiber Mediated Transduction

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 623 KB

english, 2007

964

858. Biodistribution, Persistence, Innate Immune Response and Toxicity with Nonhuman Adenoviral Vectors in the Mouse Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

965

859. Regulation of Adenovirus Infection by a Novel Protein, CAR-Like Soluble Protein (CLSP)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

966

860. Modification of the Ad35 Fiber To Ablate CD46 Binding

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

967

861. Adenovirus Serotype 35 Vector-Mediated Gene Transfer into Cynomolgus Monkeys

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 660 KB

english, 2007

968

862. A Genetically Modified Adenoviral Vector for Lung-Selective Gene Expression

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 660 KB

english, 2007

969

864. Differential Biodistribution and Physical Properties of Chimeric Ad5/40S Are Associated to Ad40 Short Fiber

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 610 KB

english, 2007

970

865. Targeting Adenovirus Vector to Neural Cell Adhesion Molecule (NCAM) for Gene Delivery to Developing Muscle

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 610 KB

english, 2007

971

867. All-Trans Retinoic Acid (ATRA) Enhances Adenovirus Specific Integrin Receptor Expression on Dendritic Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 624 KB

english, 2007

972

868. Targeting of CRAd Agent to Human Squamous Cell Carcinomas of the Head and Neck (SCCHN)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

973

869. Adenovirus Vectors Targeted to HER3/4 Receptors for Breast Cancer Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 603 KB

english, 2007

974

870. Effect of Coagulation Factor X on the Infectivity of Adenoviruses Pseudotyped with Fibers from Subgroup D

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 603 KB

english, 2007

975

871. Characterization of Coagulation Factor IX Interactions with Human Adenovirus Fiber Knob Domains Using Tandem Mass Spectrometry and Surface Plasmon Resonance

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

976

872. Chimeric Adenoviral Vectors Displaying Fibers of Subgroup B Effectively Mediate Transgene Expression into Specific Cancer Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

977

873. Circumventing Induction of Neutralizing Antibodies to Adenovirus by Manipulating Vector Dose

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

978

875. Comprehensive Search for Factors Involved in the Innate Immune Response Induced by Adenovirus Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 620 KB

english, 2007

979

877. Extended Transgene Expression from a Non-Integrating Adenoviral Vector Containing Retroviral Elements

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 626 KB

english, 2007

980

878. Genetic Incorporation of the Protein Transduction Domain of TAT into Ad5 Fiber Selectively Enhances Viral Infectivity

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 626 KB

english, 2007

981

879. Improved Design of Fiber-Mosaic Adenoviruses

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

982

880. Characterization of Potentially High Packaging Capacity Adenovirus Vector Deleting Minor Core Protein V Gene

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 603 KB

english, 2007

983

881. Hsmar2, a Newly Reconstructed Human Mariner Transposon Mediates Specific Gene Transfer in Human Cells of Expression Cassettes Flanked by TR-Hsmar2 Sequences

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 603 KB

english, 2007

984

882. Fiber-Modified Adenovirus Vectors Containing the TAT Peptide in the Fiber Knob Have Efficient Gene Transfer Activity

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 560 KB

english, 2007

985

884. Adenovirus Complementing Cell Line for the Construction of Vectors with Inhibitory Transgenes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2007

986

885. Insulated Heat Shock Promoter Is Functional in Adenovirus Vectors, but Not in Oncolytic Adenoviruses

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 589 KB

english, 2007

987

886. Three pIXs Can Be Incorporated into One Adenovirus Type 5 Virion

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 589 KB

english, 2007

988

887. Herpes Simplex Virus Type 1 Thymidine Kinase Sequence Fused to β-Galactosidase Gene Increases Levels of β-Galactosidase Activity Per Genome of Both First Generation and High-Capacity Adenoviral Vectors In Vitro and In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2007

989

888. Application of Tetracyclin Inducible Promoter Based CRAd to Cell Vehicle System

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 564 KB

english, 2007

990

889. VP16-Mediated Expression of Human Single-Chain lnterleukin-12: Highly Efficient and Suppressible Gene Expression through Adenoviral Infection in Human Colon Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 565 KB

english, 2007

991

890. Capsid Protein IIIa as a Locale for Incorporation of Heterologous Peptides on Adenovirus Type 5

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 614 KB

english, 2007

992

892. A Novel Method for Adenovirus Purification and Titration

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 614 KB

english, 2007

993

893. Mechanism of Escape from Macropinosomes for Octaarginine Modified Nanoparticles

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 577 KB

english, 2007

994

894. Novel Approach for the Nuclear Delivery of Macromolecule Via Membrane Fusion in Non-Dividing Cell

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 577 KB

english, 2007

995

895. Polymer-DNA Formulations for Gene Transfer to Skeletal and Cardiac Muscles

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 586 KB

english, 2007

996

896. Development on Optimization of a Systemic Non-Viral Gene Delivery for Cancer with a Cleavable PEG System

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 586 KB

english, 2007

997

897. Octaarginine-Modified Multifunctional Envelope-Type Nano Device for Gene Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

998

898. Skin Gene Therapy Using Chitosan Coated Liposomes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 642 KB

english, 2007

999

899. Improvement of Nuclear Transfer of pDNA with Lipid Envelope-Typed Gene Delivery System by Utilization of Sugar as a Nuclear Targeting Ligand and Control of Lipid Stability

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 642 KB

english, 2007

1000

900. Reducible Poly(Amido Ethylenetetramine) for Cardiac Gene Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 592 KB

english, 2007

1001

901. Non-Linear Pharmacodynamics in the Transfection Efficiency of a Non-Viral Gene Delivery System

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 592 KB

english, 2007

1002

902. Neural Retina Limits Delivery Non Viral Vectors to Retinal Pigment Epithelium

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2007

1003

903. Delivery of Biologically Active Nucleic Acid In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 564 KB

english, 2007

1004

904. Adjusting Chitosan-DNA Nanoparticle by Characterizing the DNA Core and Chitosan Shelter

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 564 KB

english, 2007

1005

905. Archaeosomes Based on Synthetic Tetraether-Like Lipids as Novel Versatile Gene Delivery Systems

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2007

1006

907. sRNAvalet™ Transfection Reagent

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 560 KB

english, 2007

1007

909. In Vivo Gene Transfer to Duodenal Epithelial Cells Using a Chitosan-Based Vector

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2007

1008

910. Functional Rescue of the Rds Haploinsufficency Phenotype with Non-Viral Compacted DNA Nanoparticles

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

1009

911. Radiation-Guided Gene Delivery to Lung Tumor Xenografts by Annexcin V-Conjugated Liposomal Nanovector

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

1010

912. Canine Erythropoietin as a Secreted Reporter System for the Study of Sleeping Beauty-Mediated Long-Term Expression in the Dog

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 641 KB

english, 2007

1011

913. Aerosol Gene Delivery to the Lungs of Mice Guided by Magnetic Forces

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 641 KB

english, 2007

1012

914. Gene Expression Profiles in Skeletal Muscle after DNA Electrotransfer Indicate a Highly Efficient and Safe Gene Therapy Platform

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2007

1013

915. Controlled Long-Lasting Hematocrit Increase by EPO Plasmid Electrotransfer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 487 KB

english, 2007

1014

916. Muscle Characteristics Affect Plasmid Expression Following Electroporation in Both Large and Small Animals

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 487 KB

english, 2007

1015

917. Comparison of Electroporatively Delivered Non-Compacted and Compacted DNA

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 623 KB

english, 2007

1016

918. Safety Aspects of Electro Gene Transfer (EGT) in Mouse Skeletal Muscle

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 623 KB

english, 2007

1017

919. Development of SFV Based Gene Therapies for Use in Electroporative Cancer Treatment

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

1018

922. Studies on Ultrasound-Mediated Transient Cell Membrane Permeabilisation (Sonoporation) Events In Vitro

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

1019

923. Enhanced Gene Transfer by Echo Contrast Agents: Comparison between BR1 and BR14 In Vitro and In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 575 KB

english, 2007

1020

924. Development of Minimally Invasive and Tissue Specific Gene Delivery with Novel Liposomal Bubbles

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 575 KB

english, 2007

1021

925. Engineered Modular Protein DNA-Carriers as Viral-Mimics for Intracellular Transport to the Cell Nucleus

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 588 KB

english, 2007

1022

926. Non-Viral Gene Delivery from Templated Fibrin Tissue Engineering Scaffolds for Sustained Transgene Expression

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 588 KB

english, 2007

1023

927. Controlled and Sustained Gene Release from Polymer DNA Matrices Scaffold for Heart Valve Tissue Engineering

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 588 KB

english, 2007

1024

929. New Series of Hydrophilic Polyhydroxylimine Transfection Agents

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 620 KB

english, 2007

1025

930. Photochemical Control of Oligonucleotide Knockdown Activity Using Light

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 620 KB

english, 2007

1026

932. Introduction of Imidazole to Chitosan for Enhanced Delivery of Nucleic Acids

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 653 KB

english, 2007

1027

933. In Vivo siRNA Delivery Mediated by Dendritic Poly(L-Lysine)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

1028

934. Fully 2'-Deoxy-2'-Fluoro Substituted Nucleic Acids Induce RNA Interference in Mammalian Cell Culture

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 628 KB

english, 2007

1029

935. Brain Targeted Gene Therapy for Metachromatic Leukodystrophy: In Vitro Expression and Activity of a Melanotransferrin-Arylsulfatase A Fusion Protein

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 628 KB

english, 2007

1030

936. In Vivo Efficient Gene Expression by Freeze-Dried DNA Complexes Coated by Polyanions

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2007

1031

937. Transcriptional Enhancement by Synthetic Polyampholytes Mimicking HMG Protein

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 546 KB

english, 2007

1032

938. Engineering Polypeptide-Coated Adenoviral Gene Delivery Vectors for Systemic Therapy of Prpstate Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2007

1033

939. Pharmacogenomic Analysis of Non-Viral Gene Transfer: Feasibility of Effective Cell Differentiation toward Tissue Engineering

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 581 KB

english, 2007

1034

941. Intraperitoneal Administration of Calcium Phosphate Nanoparticles Encapsulating pSVβgal Elicits Immune Response to Encoded Protein

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 637 KB

english, 2007

1035

943. Recombinant High Mobility Group B-1 Peptide for Delivery of Nucleic Acids

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

1036

944. Formulation and Characteristation of Novel Cyclodextrin Gene Delivery Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 600 KB

english, 2007

1037

945. A Novel Chitosan-Based Polymeric Gene Carrier: Galactosylated 6-Amino-6-Deoxy-Chitosan

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 600 KB

english, 2007

1038

946. Preparation of Novel Cationic Polydiacetylene Nanovesicles and Application to Gene Delivery In Vitro

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

1039

947. Mechanically Enhanced Microencapsulated Cellular Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 628 KB

english, 2007

1040

948. Long-Term Stability of Aqueous pDNA/PEI Complexes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 628 KB

english, 2007

1041

949. Design of Gene Correction Devices for Improved Recognition by Protein Involved in Homologous Recombination

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 610 KB

english, 2007

1042

950. Intraarticular Expression of Factor IX from Adeno-Associated Virus (AAV) Vectors Decreases Development of Hemophilic Joint Pathology

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 610 KB

english, 2007

1043

951. Novel AAV-FVIII Single Chain Vectors That Produce High Levels of FVIII Activity in Hemophilia A Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

1044

953. High-Level, Erythroid-Specific Human Factor IX Expression in Hematopoietic Chimeras Using Non-Myeloablative Conditioning?

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2007

1045

954. Toward Hemophilia A Gene Therapy: Safety-Modified Gammaretroviral Vector Expressing a Secretion-Enhanced FVIII Molecule with Reduced Immunogenicity

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 633 KB

english, 2007

1046

955. An Essential Role of Factor VIII Light Chain in Facilitating Heavy Chain Secretion

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 633 KB

english, 2007

1047

956. A High Specific Activity Factor VIII Variant and Its Application to AAV-Mediated Gene Transfer for Hemophilia A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

1048

957. Factoring in ΦC31 Integrase as a Cure for Hemophilia

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 640 KB

english, 2007

1049

958. A Novel Approach to Proliferate Factor IX-Producing Hepatocytes Using Urokinase-Type Plasminogen Activator Transgenic SCID Mice for Establishment of Cell-Based Therapy of Hemophilia B

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

1050

959. Specific Amino Acid Modifications To Increase Safety and Efficacy of Nonviral Gene Therapy of Factor VII for Hemophilia A with Inhibitors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 597 KB

english, 2007

1051

960. Lentiviral Modification of Liver Sinusoidal Endothelial Cells (LSEC) for Cell and Gene Therapy in Hemophilia A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 597 KB

english, 2007

1052

961. Delivery of Human Coagulation Factor VIII Gene into Skeletal Muscle Cells Using Lentiviral Vector

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 632 KB

english, 2007

1053

962. Liver-Restricted Administration of Lentiviral Vector during Isolated Hepatic Perfusion Results in Significant Reduction of Plasma Bilirubin Levels in the Gunn Rat

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 632 KB

english, 2007

1054

963. Complete Phenotype Correction in Female PKU Mice by Repeated Administrations of Murine PAH cDNA Using a Genome-Targeted phiBT1 Bacteriophage Integration System

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 632 KB

english, 2007

1055

964. Balloon Occlusion Catheter-Based Delivery of HDAd into the Nonhuman Primate Liver Results in Stable, High Level Transgene Expression with Minimal Toxicity

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 576 KB

english, 2007

1056

965. High-Pressure Delivery Via Peripheral Vein Facilitates Transduction of Canine Liver with AAV Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 576 KB

english, 2007

1057

966. Limited Correction of VLCAD Deficiency in Mice with a Native VLCAD Promoter

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

1058

967. Non-Viral Gene Transfer into Gunn Rats for Prevention of Drug Toxicity and Investigation of UGT Isoenzyme Function In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 646 KB

english, 2007

1059

968. Patent Inventorship of Principal Investigators in Phase I Gene Transfer Clinical Trials: An Empirical Analysis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 646 KB

english, 2007

1060

969. Paracrine Support Is a Predominant Mechanism by Which Pluripotent Adipose Stromal (Stem) Cells Promote Reperfusion of Ischemic Tissues

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 622 KB

english, 2007

1061

970. Characterization, Isolation and Angiogenesis of Endothelial Cells Derived from Skeletal Muscle and Heart

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 622 KB

english, 2007

1062

971. Development of High Throughput Functional Screening of Cardiovascular Therapeutic Genes Using the HVJ-E Vector and Identification of a Novel Angiogenic Peptide, AG-30

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

1063

972. P27kip1 -Loaded Nanoparticle for the Inhibition of Intimal Hyperplasia in Mice Vein Grafting Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 647 KB

english, 2007

1064

973. Protective Effects of Limited In Vivo Gene Transfer of Phospholamban Antisense in a Catecholamine Induced Hypertrophic Rat Heart Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2007

1065

974. Increased Collateral Development by Transplantation of Skeletal Myoblasts Infected with Adenoviral Vectors Expressing Hybrid Hypoxia-Inducible Factor 1α in a Rat Model of Hind Limb Ischemia

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 541 KB

english, 2007

1066

975. AP20187 Induces Insulin-Like Effects in Muscle and Liver of Diabetic Mice Transduced with AAV

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 541 KB

english, 2007

1067

976. Additive Effect of AAV Mediated VEGF Gene and Mesenchymal Stem Cell Therapies on the Treatment of Ischemic Cardiomyopathy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2007

1068

977. Optimization of Adeno-Associated Virus Mediated Apolipoprotein A-l Gene Expression in the Murine Liver

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 651 KB

english, 2007

1069

979. Chronic Expression of AZGP1 Following AAVrh.10-Mediated Gene Transfer Limits Weight Gain in Mice on High Fat Diets

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 607 KB

english, 2007

1070

982. Self-Complementary rAAV Vector for Antioxidant Gene Delivery in Mouse Liver Ischemia-Reperfusion Injury Protection

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 647 KB

english, 2007

1071

983. Rapid and Widespread GFP Expression in Murine Myocardium Using scAAV

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

1072

984. Intrabody-Mediated Redistribution of Mutant Huntingtin as Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 616 KB

english, 2007

1073

985. Modulating SMN2 Pre-mRNA Splicing: Identification of Optimal Targets for Bi-Functional RNAs

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 617 KB

english, 2007

1074

986. Herpes Simplex Virus (HSV) Vector-Mediated Delivery of Glial Cell Line Derived Neurotrophic Factor (GDNF) and the GDNF Ligand Neurturin Rescues Erectile Dysfunction Following Cavernous Nerve Injury

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

1075

987. Effects of Promoter and Viral Dose on AAV Vector-Mediated Gene Expression, Efficacy and Survival in a Mouse Model of Niemann-Pick A Disease

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 607 KB

english, 2007

1076

988. Antioxidant Enzymes Delivered Using SV40 Vectors Protect Primary Neurons In Vitro from Apoptosis Mediated by Transduced HIV-1 gp120

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 607 KB

english, 2007

1077

989. Integration-Deficient Lentiviral Vectors Mediate Efficient Gene Transfer to Nervous System and Muscle

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 620 KB

english, 2007

1078

990. Neonatal Intraperitoneal or Intravenous rAAV8 Injections for Targeting Lower Motor Neurons

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 619 KB

english, 2007

1079

991. Retrograde Axonal Transport of AAV Vectors Allows Extended Restoration of Dystrophin Expression by Exon Skipping in mdx Mice Brain

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

1080

992. Ultrasound-Mediated Gene Transfer of HGF Improved Abeta-lnduced Cognitive Impairment in Mice Associated with Upregulation of BDNF, Recovery of and Downregulation of Oxidative Stress

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

1081

993. Gene Delivery and Biodistribution in the Brain Following Adeno-Associated Virus Serotype 5 Vector-Mediated Gene Transfer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

1082

994. Neural Expression of G Protein-Coupled Receptors GPR3, GPR6, and GPR12 Upregulates Cyclic AMP Levels and Promotes Neurite Outgrowth

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 571 KB

english, 2007

1083

995. Enhanced Gene Transfer to Photoreceptors by Adenovirus Vectors Deleted in RGD Penton - Application to the Rescue of Photoreceptor Degeneration in Two Models of Retinitis Pigmentosa

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 571 KB

english, 2007

1084

996. Intracerebral Delivery of AAV-2/5 Vectors To Treat Canine MPS IIIB

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

1085

997. Disseminated Gene Transfer to the CNS by Intraventricular Injection with Mannitol Pretreatment Using SV40-Derived Vectors Delivers Generalized Transgene Expression throughout the Brain

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 630 KB

english, 2007

1086

998. Simultaneous Silencing of Vanilloid Receptor TRPV1 and Pain-Related Cation-Channel P2X3 with a Single Lentiviral Vector Reduces Neuropathic Pain In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 630 KB

english, 2007

1087

1000. Nerve-Directed Enkephalin Expression for Pain Therapy Report of Preclinical Safety and Efficacy Studies

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 632 KB

english, 2007

1088

1001. Efficient Synapsin-dsRed and Synapsin-EGFP Labeling of Rat Neuronal Precursors and Human Postmitotic NT Neurons for Grafting in Rats with Spinal Ischemia-Induced Paraplegia

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

1089

1002. Adeno-Associated Virus Gene Therapy of Feline Gangliosidosis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 585 KB

english, 2007

1090

1003. Glaucoma Gene Therapy: COX-2 and the Prostaglandin F Receptor Combined Reduce Intraocular Pressure in the Cat Eye

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 585 KB

english, 2007

1091

1004. Repeated Administration of Lentiviral Vector to Mouse Nasal Epithelia Enhances Expression without Emergence of Blocking Mucosal Immune Responses

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2007

1092

1005. Lifetime Airway Gene Expression from a Single Lentivirus Dose?

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

1093

1006. Electroporation-Mediated Gene Transfer of the β2-Adrenergic Receptor Reduces Bronchoconstriction in a Mouse Asthma Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

1094

1007. Development of an Integrase Deficient Lentiviral Vector for Transient shRNA Expression in Respiratory Epithelia

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 632 KB

english, 2007

1095

1009. Expression of the Cystic Fibrosis Transmembrane Regulator (CFTR) Protein Following Recombination between Two AAV Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

1096

1010. Evidence of Progenitor Cell Transduction in Mouse Nasal Epithelium with Lentiviral Vector Pseudotyped with Sendai Virus Envelopes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 617 KB

english, 2007

1097

1011. Evaluation of Host Immune Response as a Barrier To Repeat Intranasal Administration of Lentivectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 617 KB

english, 2007

1098

1012. Non-Invasive Imaging of Airways and Other Organs at High Resolution in Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

1099

1013. The Route of Luciferin Administration Is a Critical Determinant of Detection of Pulmonary and Nasal Luciferase Expression by In Vivo Bioimaging

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 663 KB

english, 2007

1100

1014. Lentiviral Vector-Mediated Expression and Activity of Small Hairpin RNA Interference for the Epithelial Sodium Channel in Functional Models of Human Airway Epithelium

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

1101

1015. CpG-Dependent Inflammatory Response after Delivery of Lipid/pDNA Complexes to Murine Lungs

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 576 KB

english, 2007

1102

1016. Rabbit Model for Airway Gene Delivery of Helper-Dependent Adenoviral Vectors Using Novel Aerosol Formulations

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 576 KB

english, 2007

1103

1017. In Vivo Imaging of Cationic Lipid 67-Mediated Gene Transfer in Mouse Lung

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2007

1104

1019. Using Comparative Proteomics as a Tool for Target Selection and Validation for Personalized RNAi Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 611 KB

english, 2007

1105

1020. Why Simple Cationic Liposome Formulations Fail To Deliver siRNA Efficiently In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

1106

1021. Highly Effective Bi-Functional shRNAs for Cancer Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

1107

1022. Delivery of a lacZ shRNA to Muscles of the ROSA26 Mouse

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

1108

1023. Chitosan Oligomers as siRNA Delivery Systems In Vitro

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

1109

1025. Silencing of Microphage Migration Inhibitory Factor (MIF) Via siRNA Causes Attenuation of Growth and Induction of Apoptosis in Human Prostate Cancer Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 620 KB

english, 2007

1110

1026. Gene Silencing for Epidermal Growth Factor Receptor Variant-Ill Induces Cell-Specific Cytotoxicity

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

1111

1027. siRNA Pool Targeting Different Sites of Human Hepatitis B Surface Antigen Efficiently Inhibits HBV Infection

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 619 KB

english, 2007

1112

1028. Genetic Knock-Down of Human TNF-α by Lentivirus-Encoded shRNAs

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 619 KB

english, 2007

1113

1029. Specific and Efficient Regression of Hepatocarcinoma In Vivo by Liver-Specific Expression of hTERT-Targeting Trans-Splicing Ribozyme

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

1114

1030. Silencing of Macrophage Scavenger Receptor A and CD36 by RNA Interference Decreases Foam Cell Formation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 625 KB

english, 2007

1115

1031. Gene Expression and Silencing for Successful Islet Transplantation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 625 KB

english, 2007

1116

1032. Plasmid Based RNA Interference Controls lnterleukin-1 Expression in Osteoarthritis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2007

1117

1037. Foamy Virus Vectors for Gene Therapy in Human Embryonic Stem Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 622 KB

english, 2007

1118

1038. Tissue Distribution of Human Multipotent Stromal Cells (hMSCs) after Intravenous or Intracardiac Infusion into Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 622 KB

english, 2007

1119

1039. Gene Therapy for Bone Tissue Engineering Using a Combination of 3-D Tissue Engineered Scaffold and Non-Viral Gene Carrier

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

1120

1042. Human Adipocyte-Derived Stroma Cells Exert Potent Antitumorogenic Effects in Pancreatic Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

1121

1043. Bone Marrow Stem Cell Gene Transfer as a Means To Deliver Genes to Injured Liver

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

1122

1044. Syngeneic Bone Marrow Transplant in a Murine Model of Mucopolysaccharidosis Type I

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

1123

1045. Ex Vivo Transduction and Transplantation of Bone Marrow Cells for Liver Gene Delivery of alpha-1 Antitrypsin (AAT)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

1124

1046. Non-Viral Genetic Modification of Stem Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 624 KB

english, 2007

1125

1047. Evaluation of MIP-1α Effect on Transduction Rate of Gal-v Oncovirus on Cord Blood Stem Cell

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 624 KB

english, 2007

1126

1048. Gene Expression in Differentiating Human ES Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

1127

1049. Human Multipotential Stromal Cells (MSCs) Repeatedly Create Their Own Niches as They Are Expanded and Re-Expanded from Single Cells into Colonies

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 577 KB

english, 2007

1128

1050. Combined Modality Therapy of Locally Advanced Pancreas Cancer (LAPC) Integrating Radiation Inducible Gene Therapy with TNFerade™: Preliminary Results of a Randomized Phase ll/lll Trial

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 578 KB

english, 2007

1129

1051. Regression of Glioblastoma Multiforme Following Intracranial Infusions of IL13-Zetakine+/ HyTK+ CTL Clones

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 588 KB

english, 2007

1130

1052. NV1020, a Genetically-Engineered Oncolytic Herpes Simplex Virus Type 1, for Human Colorectal Cancer Metastatic to the Liver

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 588 KB

english, 2007

1131

1053. A Phase 1/2 Clinical Study of Intra-Articular Administration of a Recombinant Adeno-Associated Vector Containing a TNF-α Antagonist Gene in Inflammatory Arthritis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

1132

1054. Phase I Clinical Trials of Intramuscular Injection of rAAV2 and rAAV1-Pseudotyped Versions of an Alpha-1 Antitrypsin (AAT) Vector in AAT-Deficient Adults

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 626 KB

english, 2007

1133

1056. Intramuscular Administration of an AAV-1 Vector in Humans Results in Capsid-Specific T Cell Responses

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 601 KB

english, 2007

1134

1057. Abstract Withdrawn

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

1135

1059. The GTSG.org Database: A First Meta-Analysis of More Than 11.300 Retroviral Gene Therapy Vector Insertion Sites

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 622 KB

english, 2007

1136

1060. Hot Spots of Retroviral Integration in Human CD34* Hematopoietic Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 622 KB

english, 2007

1137

1061. Self-Inactivating Retroviral Vectors Harboring Cellular Promoters Reduce the Risk of Insertional Transactivation and Transformation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

1138

1062. Validating Assays for Vector-Mediated Genotoxicity

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 634 KB

english, 2007

1139

1063. Modeling the Genotoxicity of Viral Vector Integration in a Tumor Prone Hematopoietic Stem Cell Transplantation Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

1140

1064. HIV-Derived Lentivector Particles Persist in Hematopoietic Target Cells and Exhibit Delayed Release Kinetics

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 588 KB

english, 2007

1141

1065. Neonatal Retroviral Vector Gene Therapy Does Not Induce Tumors in Normal C57BL/6 Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 588 KB

english, 2007

1142

1066. A New Platform for Targeted siRNA Delivery In Vivo: Dynamic Polyconjugates

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 632 KB

english, 2007

1143

1067. Design and Small Animal Imaging of PEG-Stabilized DNA Nanoparticles Retargeted to the Liver

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 632 KB

english, 2007

1144

1068. Aerosol Delivery of Concentrated pDNA/ PEI Formulations to the Sheep Lung

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2007

1145

1069. Prolonged Gene Silencing in Hepatoma Cells and Primary Hepatocytes after siRNA Delivery with Biodegradable Poly(β-Amino Ester)s

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 571 KB

english, 2007

1146

1071. Novel Cancer Cell-Specific Gene Expression Using PKCalpher-Responsive Peptide/Polymer Conjugate

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 658 KB

english, 2007

1147

1072. Target Specific Gene Delivery to Liver by a Novel Class of Bi-Functional Compounds

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 658 KB

english, 2007

1148

1073. Highly Efficient Gene Transfer with a Novel Degradable Pseudodendritic Oligoamine: An In Vitro and In Vivo Study

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2007

1149

1075. A Clinically Relevant Gene Therapy Approach for Duchenne Muscular Dystrophy by Vascular Delivery of Micro-Dystrophin

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 624 KB

english, 2007

1150

1076. Prolonged AAV-Mediated Dystrophin Expression in a Canine Model of Duchenne Muscular Dystrophy with a Brief Course of Immunosuppression

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 627 KB

english, 2007

1151

1077. Inhibition of Myostatin by Gene Therapy Increases Muscle Mass and Strength in a Mouse Model of Muscular Dystrophy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 627 KB

english, 2007

1152

1078. AAV Vector-Mediated Expression of Follistatin Stimulates Skeletal Muscle Hypertrophy and Can Enhance Functional Performance in Models of Muscle Disease

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

1153

1079. Inhibiting Myostatin in Dystrophic Mice with Follistatin Improves the Success of Myoblast Transplantation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

1154

1080. Vascular Endothelial Growth Factor Overexpression Improved Survival and Engraftment of Human Myoblasts into SCID Mouse Muscles

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

1155

1081. Transplantation of Autologous Genetically Modified Myoblasts: A Possible Treatment for Recessive Muscular Dystrophies

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

1156

1082. A microRNA-Regulated Lentiviral Vector Can Mediate Stable Gene Transfer and Antigen-Specific Immunological Tolerance Following Systemic Administration

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 655 KB

english, 2007

1157

1083. Adoptive Therapy of Tolerogenic Dendritic Cells Mediates Factor VIII Persistence in Hemophilia A Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 655 KB

english, 2007

1158

1084. Early Fetal Gene Delivery Induces Both Central and Peripheral Immune Tolerance

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 632 KB

english, 2007

1159

1085. Modulating T Cell-Dependent Tolerance to the Transgene Product in Non-Human Primate Model of AAV-Mediated Liver Gene Transfer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 632 KB

english, 2007

1160

1086. Transgene Immunity Dictates the Stability of Efficient EGFP Gene Transfer by Conventional (ss) and Self Complementary (sc) AAV7 Vectors in Nonhuman Primate Liver

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

1161

1087. Transient Blockade of ICOS Co-Stimulatory Pathways Induced Long-Term Tolerance to Factor VIII Following Nonviral Gene Transfer of Factor VIII into Hemophilia A Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 641 KB

english, 2007

1162

1088. Toll-Like Receptors Activation in the Innate and Adaptive Immune Response to Helper Dependent Adenoviral Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

1163

1089. An In Vitro Model of CD8+ T Cell-Mediated Killing of AAV-Transduced Human Hepatocytes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 625 KB

english, 2007

1164

1091. Induction of Molecular Chimerism in Rhesus Macaques Reconstituted with Autologous CD34+ Cells Transduced with the Gene Encoding the α(1-3)galactosyltranferase (αGT)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2007

1165

1092. Long-Term Retrovirus Expression in Neural Stem Cells and Their Neuronal Progeny for MeCP2 Gene Therapy of Rett Syndrome

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 667 KB

english, 2007

1166

1093. Comparison of dsAAV Serotypes for Therapeutic Gene Transfer to Islets for Abrogation of Autoimmunity in Diabetes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 667 KB

english, 2007

1167

1094. Biological Identification of Ankyrin-1 Promoters Transcribed at Higher Rates for Globin Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 569 KB

english, 2007

1168

1095. Neuronal Apoptosis Related to HIV-1 gp120 Can Be Inhibited by Different Strategies Using rSV40-Delivery of Antioxidant Enzymes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 569 KB

english, 2007

1169

1096. Targeted Expression of BikDD Eradicates Pancreatic Tumors in Noninvasive Imaging Models

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 555 KB

english, 2007

1170

1098. Inhibition of HIV-1 Replication by Lentiviral Vectors Harboring Long Hairpin RNAs

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 611 KB

english, 2007

1171

1100. Novel Cell Type-Specifical Aptamer-siRNA Delivery System for HIV-1 Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 611 KB

english, 2007

1172

1101. Rational Design Leads to More Potent RNA Interference Targeting Hepatitis B Virus

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

1173

1102. Novel “Bifunctional” shRNA Knockdown Therapeutics to Individualized Cancer Targets

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 645 KB

english, 2007

1174

1103. Using Let-7 microRNA To Inhibit Pancreatic Cancer Cells Proliferation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 645 KB

english, 2007

1175

1104. Argonaute-2 Is a Key Limiting Factor for Therapeutic RNAi in the Liver

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

1176

1105. Prevention and Reversal of Autoimmune Diabetes by Microsphere-Formulated Antisense Oligonucleotiudes Targeting Costimulation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 634 KB

english, 2007

1177

1106. High Proteasome Activity Is a Common Feature among Stem Cells of Different Lineages and Restricts Lentiviral Gene Transfer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

1178

1107. Enhanced Levels of the Gata-2 Transcription Factor Result in Myeloid Expansion Coupled with Inhibition of Lymphoid Development in the Absence of Leukemia

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 647 KB

english, 2007

1179

1108. Targeting p18lnk4c for Ex Vivo Expansion of Human Hematopoietic Stem Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 647 KB

english, 2007

1180

1109. Increased Proliferation and Self Renewal Capacity of CD34+ Sca-1 + Putative Stem

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 642 KB

english, 2007

1181

1110. Prospective Isolation of Multipotent Adult Stem Cells from Skeletal Muscle

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 642 KB

english, 2007

1182

1111. Attempt for Enrichment and Characterization of Ovarian Cancer Stem Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

1183

1112. Bone Marrow Is an Essential Source of Keratinocytes in the Grafted Skin

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 564 KB

english, 2007

1184

1113. Inducible LRP5 (iLRPS) Recapitulates Role of LRP5 Dimerization in Wnt/β-Catenin Signaling and Stem Cell Expansion

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 564 KB

english, 2007

1185

8. Extensive AAV Epidemiological Study Identifies a Novel AAV Variant with Low Seroprevalence

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 564 KB

english, 2007

1186

13. Toxicology of PEGylated Helper-Dependent Adenovirus in Non-Human Primates

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 602 KB

english, 2007

1187

26. Correction of Brain Lesions in MPS I Dogs after Neonatal Systemic Gene Therapy May Involve Migration of Blood Cells into the Brain

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 604 KB

english, 2007

1188

28. Targeted Delivery of Glycine Receptors to Peripheral Neurons as Treatment for Pain

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

1189

30. Neuronal Specificity of HSV/Sleeping Beauty Amplicon Transduction In Utero Is Driven Primarily by Tropism and Cellular Co-Factor Expression Profiles during Embryogenesis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

1190

39. CD3/CD28 Activation and Culture with IL-7 and IL-15 Permit Efficient Transfer of a Suicide Gene in Highly Alloreactive Central Memory Lymphocytes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 614 KB

english, 2007

1191

44. Phase I Study of Ad5-TRAIL in Men with Clinically Organ Confined Prostate Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 591 KB

english, 2007

1192

47. Heat Shock Protein Inhibitors Increase the Efficacy of Measles Virotherapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

1193

49. Exponential Enhancement of Oncolytic VSV Potency by Vector-Mediated Suppression of Anti-Viral Inflammatory Responses In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 644 KB

english, 2007

1194

51. IL13 Displaying Retargeted Oncolytic Measles Virus (MV) Strains Have Significant Activity and Improved Therapeutic Index Against Gliomas

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 602 KB

english, 2007

1195

62. Deciphering microRNA Function in the CNS

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 597 KB

english, 2007

1196

67. Multiple Tandem Insulators May Reduce Retroviral Insertional Activation of Oncogenes and Lymphomagenesis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 604 KB

english, 2007

1197

75. Targeting of Angiogenic Endothelial Cells Using a New AAV-2 Insertion Site

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

1198

77. Genetic Modification of AAV1 Capsid for WN Targeted Gene Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 633 KB

english, 2007

1199

79. Making AAV Chimeras by STEP and Shuffle

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 638 KB

english, 2007

1200

81. Directed Evolution of Adeno-Associated Virus in Primary Human Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 629 KB

english, 2007

1201

82. Production of Infectious AAV Vectors in Insect Cells Using Novel Designed Rep and Cap Expression Cassettes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 629 KB

english, 2007

1202

97. Long-Term Somatic Correction in MPS II Mice Using a Self-Complimentary AAV2 Vector

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 623 KB

english, 2007

1203

98. Active Enzyme Fusions for Therapeutic Targeting of the Central Nervous System Via the Peripheral Circulation in Mucopolysaccharidosis Type NIB

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 573 KB

english, 2007

1204

106. Treatment of Diabetic Rats with Encapsulated Islets

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 648 KB

english, 2007

1205

120. Proper Timing of VEGF Expression Is Required for the Formation of Stable and Mature Blood Vessels

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2007

1206

130. Independent Canine Models of Duchenne Muscular Dystrophy Due to Intronic Insertions of Repetitive DNA

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 645 KB

english, 2007

1207

132. Gene Therapy for Duchenne Muscular Dystrophy by the Helper-Dependent Adenovirus Vector (HDAdv) - Mediated Full-Length Dystrophin Expression

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 636 KB

english, 2007

1208

133. Complementary Dystrophin and Utrophin Expression Prevents Severe Dilated Cardiomyopathy in 2-Year-Old Mdx Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 636 KB

english, 2007

1209

137. Global Force Improvement by Systemic AAV Delivery of α-Sarcoglycan Transgene in Deficient Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

1210

141. GNE Vector Development and Testing for Gene Replacement Treatment of Hereditary Inclusion Body Myopathy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 601 KB

english, 2007

1211

152. Immunogenicity of a Cytokine Enhanced Multi-Antigen pDNA Vaccine with and without In Vivo Electroporation in Rhesus Macaques

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 645 KB

english, 2007

1212

155. Partial Protection Against H5N1 Influenza in Mice with a Single Dose of a Chimpanzee Adenovirus Vector Expressing Nucleoprotein

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 612 KB

english, 2007

1213

162. Antigenic Correlates of Immunity to Avian Influenza Provided by Consensus DNA Immunogens

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 609 KB

english, 2007

1214

166. The Opposite Effect of Lipopolysaccharide on the Antitumor Therapeutic Efficacy of DNA Vaccine

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 601 KB

english, 2007

1215

169. Combination Oncolytic Herpes Simplex Virus and Dendritic Cell Immunotherapy for the Treatment of Established Murine Neuroblastomas

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2007

1216

175. Single Dosage Surface Functionalized Microparticles for Combinatorial DNA and Oligonucleotide/Adjuvant Immunization

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2007

1217

180. Induction of Anti-Tumor Immunity by the Baculovirus Autographa Californica Multiple Nuclear Polyhedrosis Virus

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2007

1218

182. Progress in the Clinical Development of a Novel IL-12 Gene Therapeutic for the Treatment of Recurrent Ovarian Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 609 KB

english, 2007

1219

196. Adenoviral Delivery of Secretable Trimeric TRAIL in Combination with Conventional Chemotherapy for Brain Tumors Induces Synergistic Tumor Suppression and Improves Survival in an Intracranial Human Malignant Glioma Xenograft Mouse Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2007

1220

199. Overexpression of Mitochondrial Localized (mt)-Catalase Further Increases Radioresistance Induced by Manganese Superoxide Dismutase (MnSOD) Overexpression in 32D cl 3 Murine Hematopoietic Progenitor Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

1221

212. Systemic Expression of Pro-Opiomelanocortin Prohormone Induces Melanogenesis and Tumor Regression in B16-F10 Melanoma

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 628 KB

english, 2007

1222

226. PTTG1 Is a Prognostic Factor and a Potential Therapeutic Target in Esophageal Squamous Cell Carcinoma

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

1223

233. Non-Invasive Bioluminescence and PET Imaging Detection of Prostate Cancer Lymph Node Metastases by Transcriptionally-Targeted Adenoviral Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2007

1224

240. In Vivo Expansion of Integration Clones Caused by Retroviral Activation of MDS1-EVI1, PRDM16 or SETBP1 in a Successful Clinical Chronic Granulomatous Disease (CGD) Gene Therapy Trial

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 588 KB

english, 2007

1225

244. Role of Chromatin Structure in Integration Site Selection of Helper-Dependent Ad5/35 Vectors Carrying the Globin LCR

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 658 KB

english, 2007

1226

247. Long-Term Efficacy and Safety of Hematopoietic Stem Cell Gene Therapy in the Murine Model of Wiskott-Aldrich Syndrome

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2007

1227

254. AAV In Vivo Gene Transfer Suppresses Adaptive Immune Responses Against α-1 Antitrypsin

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2007

1228

258. Lentiviral-Mediated Gene Transfer to Lung Activates Transgene and Vector Specific T Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 640 KB

english, 2007

1229

259. Characterization of AAV Capsid Responses in Humans Using Normal Donor Splenocytes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 640 KB

english, 2007

1230

263. Efficient Induction of Immune Tolerance to FIX Following Direct Intramuscular Gene Transfer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2007

1231

267. Gene Targeting Induced by Engineered Endonucleases Derived from the I-Crel Meganuclease

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 551 KB

english, 2007

1232

296. Transient Gene Expression, Random Chromosomal Integration and Homologous Recombination in Cynomolgus Monkey Embryonic Stem Cells with Helper-Dependent Adenoviral Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 587 KB

english, 2007

1233

301. Mobilization in a Thalassemic Mouse Model: Implications for Gene Therapy of Thalassemia

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 641 KB

english, 2007

1234

315. Optimization of Retrovirus Vector Mediated Gene Transfer Efficacy in the Closed System with the Combination of RetroNectin® Pre-Loading and Low-Speed Centrifugation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 637 KB

english, 2007

1235

318. Engineering Polarized Epithelial Cells To Secrete Fluid Unidirectionally

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 623 KB

english, 2007

1236

321. Efficient Gene Correction and Targeted Gene Addition in Human Stem Cells Using Engineered Zinc Finger Nucleases and Integrase-Defective Lentiviral Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 623 KB

english, 2007

1237

323. Efficient Engraftment and In Vivo Selection of MGMT Gene-Modified Cells Following Nonmyeloablative Conditioning with BCNU and Temozolomide in the Dog Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 651 KB

english, 2007

1238

326. Insertion of an Internal Intron Increases Transgene Expression Levels from a Bicistronic Lentivirus Vector

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 608 KB

english, 2007

1239

335. Spliceform Specific Coxsackie-Adenovirus Receptor Interactions with MAGI-1b

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 565 KB

english, 2007

1240

342. CpGs Influence the Duration of Gene Expression from Plasmid Vectors after In Vivo Lung Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

1241

366. Novel AAV Vaccine Vector Circumvents Pre-Existing Immunity in Human Populations

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2007

1242

381. Urokinase-Targeted Oncolytic Sendai Virus Vectors, Which Are Activated under Urokinase-Rich Environment, Selectively Kills Solid Tumor Via Syncytia Formation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 620 KB

english, 2007

1243

386. AAV Exploits Conditions of Cellular Stress

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 586 KB

english, 2007

1244

391. Long-Term Regulated Functional Complementation of LDLR Deficiency in Cells Using iBAC-SMAR-LDLR, a Novel Infectious Genomic DNA Episomal Vector

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 571 KB

english, 2007

1245

394. Neuroblastoma-Derived “Tumorspheres” with Cancer Stem Cell-Like Properties Are Sensitive to a Transcriptionally Targeted Oncolytic Herpes Simplex Virus

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2007

1246

400. Mechanism for Difference in the Transcription Activity of Nucleus-Delivered Transgene Introduced by Adenovirus and Lipoplex

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 521 KB

english, 2007

1247

411. Amelioration of Arthritis Following Intra-Articular Administration of an Adeno-Associated Virus Type 5 Expressing lnterferon-β under Control of a Disease Inducible Promoter

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2007

1248

420. Persistent Gene Expression in the Ovine Lung from a Human Elongation Factor 1 Alpha Promoter Plasmid Following Non-Viral Gene Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

1249

422. Changing the HLA Type of Human Embryonic Stem Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 624 KB

english, 2007

1250

430. Engineering of Packaging Cell Lines for the Biomanufacturing of Retroviral Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

1251

431. Large-Scale Production of Lentiviral Vectors Using Adherent and Suspension-Adapted Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 572 KB

english, 2007

1252

432. Process Characterization and GMP Manufacture of a Gene Transfer Vector for Leber Congenital Amaurosis

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 572 KB

english, 2007

1253

441. Properties of Human Dendritic Cells after High Titer Infection with Oncolytic Adenoviruses

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 641 KB

english, 2007

1254

442. Examination of the Therapeutic Potential of an Engineered VEGF-A Transcription Activator in a Spinal Cord Injury Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

1255

446. Antiviral Activity of Cidofovir Against Telomerase-Specific Replication-Competent Adenovirus, Telomelysin (OBP-301)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

1256

472. Modulation of Microglial Cells towards a Neuroprotective Profile Using the δRR Vector To Deliver the HSV-2 Protein ICP10PK

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

1257

473. Genetic Restoration of Ataxia Telangiectasia Cells Using a Human Artificial Chromosome Mediated-Genomic Cloning System

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

1258

474. Smooth Muscle-Specific Non-Viral Gene Therapy Using Plasmid Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 643 KB

english, 2007

1259

477. Effects of Hypoxia Response Element and DNA Targeting Sequence in VEGF Gene Expression in Hypoxia and Normoxia

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 531 KB

english, 2007

1260

488. Hydrodynamics and Ultrasound-Based Transfection of Heart with Plasmid DNA

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 494 KB

english, 2007

1261

499. Sequence Preferences of Plasmid-Microtubule Interactions

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 624 KB

english, 2007

1262

506. Analysis of the Intracellular Barriers Encountered by Nonviral Gene Carriers Following Localized Delivery to Axon Terminals

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 559 KB

english, 2007

1263

516. Cdk2 Phosphorylation Correlates Positively with Cell Surface Nucleolin Expression

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 626 KB

english, 2007

1264

523. Peptide Modified Plasmid DNA for Gene Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

1265

528. Modulation of the Human Rhodopsin Expression by Artificial Zinc Finger Transcription Factors To Treat Dominant Retinal Degenerations

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

1266

530. Protecting from Abnormal Blood Brain Barrier Permeability by Antioxidant Gene Delivery to the CNS Using SV40-Derived Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 579 KB

english, 2007

1267

549. Bone Morphogenetic Protein-2 Gene Therapy on Ovariectomized Mice Model Using Ex Vivo Modified Mesenchymal Stem Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 596 KB

english, 2007

1268

553. Efficient In Vivo Non-Viral Gene Therapy Using Hydrodynamic Delivery of Folate-PEG-Chitosan-DNA Nanoparticles in an Adjuvant-Induced Arthritis (AIA) Rat Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 529 KB

english, 2007

1269

574. Development of Simian Adenovirus Vector Based and CD8 T Cell Directed Novel Genetic Vaccines for Dengue Virus Infection

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 645 KB

english, 2007

1270

577. Development of Potent Anti-HIV Chimeric Immune Receptors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 604 KB

english, 2007

1271

584. Surface Expression of Anti-CD3 Single-Chain Antibody and CD86 on B16 Melanoma Cells Elicits Effective Anti-Tumor Immunity

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

1272

586. Investigation of Single Chain MHC Molecules for Specific Cancer Treatment

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

1273

593. Enhanced T Cell-Mediated Antitumor Efficacy of Oncolytic Adenovirus Expressing IL-12 and GM-CSF

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 592 KB

english, 2007

1274

594. The CE7R Chimeric Antigen Receptor Re-Directs T Cell Specificity to a Broad Range of L1-CAM Expressing Human Malignancies

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 592 KB

english, 2007

1275

595. Activation of Tumor-Specific CD8+ T Cells after Intratumoral Ad5-TRAIL/CpG ODN Combination Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 592 KB

english, 2007

1276

600. Valproic Acid (VPA) Enhances the Antitumor Effect of Telomerase-Specific Replication-Competent Adenoviral Agent OBP-301 (Telomelysin) in Human Lung Cancer Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 593 KB

english, 2007

1277

617. A Serotype 3 Retargeted Oncolytic Adenovirus That Expresses a TK-GFP Fusion Protein for Imageable Combined Modality Treatment of Ovarian Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 604 KB

english, 2007

1278

620. An Efficient and Safe Herpes Simplex Virus Type 1 Amplicon Vector for Transcriptionally Targeted Therapy of Human Hepatocellular Carcinomas

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1002 KB

english, 2007

1279

623. Dual Luciferase Imaging for Evaluation of the Specificity of Adenoviruses with Hypoxia Response Elements in Renal Tumors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 618 KB

english, 2007

1280

625. Inhibition of Hepatic Metastasis of Colon Carcinoma Cells by RNA Interference-Mediated Suppression of HIF-1α in Tumor Cells and Hepatocytes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

1281

627. Development of a Highly Efficient Targeted Gene Therapy Vector for the Treatment and Diagnosis of Metastatic Breast Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 626 KB

english, 2007

1282

630. VEGFR1 Targeted Oncolytic Virotherapy of Breast Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2007

1283

635. Conditionally Replicating Transductionally Targeted Adenovirus Ad5/35-TERT Is More Effective Against Head and Neck Cancer Than Non-Targeted CRAD Ad5-TERT

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

1284

638. Telomerase-Targeted Oncolytic Adenovirus in Combination with Chemotherapy Elicits Enhanced Cytopathic and Anti-Tumor Effects in Head & Neck Squamous Cell Carcinoma

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

1285

643. Development of Tenascin-C Binding Peptide Aptamers as the Tumor Targeting Tools

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 617 KB

english, 2007

1286

648. Pre-Clinical Evaluations of the Biosafety of a Lentiviral Vector Developed for the Gene Therapy of Wiskott Aldrich Syndrome

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 641 KB

english, 2007

1287

651. Gene Therapy for Beta-Thalassemia: Studies on Human Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 614 KB

english, 2007

1288

659. TLR4 and TRIF Play Positive and Negative Roles in Ad Induced Innate Immunity In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

1289

664. Identification of TLR2 as a Mediator of the Innate Immune Response to Adenoviral Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

1290

665. Host Response to Adenovirus, Helper-Dependent Adenovirus and Adeno-Associated Virus in Mouse Liver

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 605 KB

english, 2007

1291

673. The Evaluation of Novel Photoreceptor Specific Promoters in an EIAV Lentiviral Vector for Targeted Gene Expression in the Photoreceptors of the Eye

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 553 KB

english, 2007

1292

679. Sensitive and Precise Regulation of Haemoglobin after Gene Transfer of Erythropoietin to Muscle Tissue Using Electroporation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 581 KB

english, 2007

1293

680. Alcohol Drinker Rats Lower Their Ethanol Intake for One Month after a Single Injection of an Adenoviral Vector Carrying an Antisense Gene for Aldehyde Dehydrogenase

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 639 KB

english, 2007

1294

682. A New Experimental Model for HIV-1 Lesions in the Brain Based on SV40 Vectors Expressing Envelope Glycoprotein gp120

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

1295

688. Aiming at Alcoholism with Ribozyme Genes: Silencing the mRNA for an Alcohol Detoxifying Enzyme

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 585 KB

english, 2007

1296

690. Corneal Gene Therapy: Past Experiences, Current Trends and Future Perspectives

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2007

1297

702. Inhibition of TGF-β Receptor II Expression by Targeting Both Coding and Promoter Regions of the Gene in Hepatic Stellate Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 645 KB

english, 2007

1298

705. Lentiviral RNAi-Vectors Utilizing Pol II-Promoters for Use in the Brain

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 629 KB

english, 2007

1299

737. Novel Layer-by-Layer Polyplexes Using Poly(Ethylenimine) and Poly(Acrylic Acid) for Gene Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 625 KB

english, 2007

1300

774. Understanding and Exploiting Endogenous microRNA Regulation for Controlling Gene Expression

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 644 KB

english, 2007

1301

787. Non-Transmissible SeV Encoding Murine GM-CSF, Another Potent Vector System To Produce Autologous Tumor Vaccines

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 613 KB

english, 2007

1302

789. Inhibition of HIV-1 Replication by a Combination of RNaseP and 3'tRNase-Associated External Guide Sequences (EGSs) in Mammalian Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 614 KB

english, 2007

1303

795. Efficient In Vivo Transduction Using RNA Replicon Vector Derived from Sendai Virus Self-Replicating Ribonucleoprotein Complexes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

1304

803. Optimization of the Stem and Loop of shRNA Lentiviral Constructs for Stable RNA Interference into Human Hematopoietic Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 625 KB

english, 2007

1305

822. Comparative Analysis of Multiple AAV Vector Serotypes in the Mouse Brain

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 631 KB

english, 2007

1306

836. Seropositivity Against AAV Serotypes 1, 8 and 9 in Cynomolgus Monkey Colonies

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 628 KB

english, 2007

1307

839. Distinct Immunoglobulin G Subclass Responses Following Natural Exposure or Vector Infusion of Adeno-Associated Virus in Humans

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 649 KB

english, 2007

1308

840. Liver Directed AAV-Mediated Homologous Recombination Is Independent of Serotype

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

1309

851. The Effect of Genome Size and Design of scAAV Vectors on Efficiency of shRNA Expression and Gene Knockdown

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 614 KB

english, 2007

1310

853. Characteristics of Transduction by Self-Complementary Adeno-Associated Virus Serotypes in Human Monocyte-Derived Dendritic Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 597 KB

english, 2007

1311

863. The KKTK Motif in the Human Adenovirus Serotype 5 Fiber Shaft Domain Is Not Essential for Efficient Virus Infection of Liver Cells In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

1312

866. Development of Peptide Targeted Adenovirus with the pFex System

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 624 KB

english, 2007

1313

874. Design and Characterization of Her2-Targeted Adenovirus Vectors

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

1314

876. Tropism Analysis of Several Primate-Derived Adenoviral Vectors in Leukemia Cell Lines

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 620 KB

english, 2007

1315

883. Localized Viral Gene Delivery through Co-Axial Electrospun Fibers

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 559 KB

english, 2007

1316

891. Adenovirus 35 Vectors with Improved Transgene Capacity, and Ease of Production

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 614 KB

english, 2007

1317

906. Charge-Reversal Amphiphiles for DNA and siRNA Transfection

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 560 KB

english, 2007

1318

908. Peptidic Based Amphiphiles for Gene Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 560 KB

english, 2007

1319

920. Combined Electroporation and Ultrasound for Use in Chemotherapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 619 KB

english, 2007

1320

921. Optimizing Ultrasound Conditions and Microbubble Concentration for Efficient Gene Transfer in Human Glioblastoma Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 619 KB

english, 2007

1321

928. Bioresponsive Endosomolytic Conjugates for DNA and siRNA Delivery

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 620 KB

english, 2007

1322

931. Development of Bifunctional Polyethylene Glycol Gene Delivery Vehicles

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007

1323

940. Efficient Delivery of Small Interfering RNA in Two Models: Vascular System in Vertebrate Embryo and Experimental Arthritis in Mouse

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 581 KB

english, 2007

1324

942. Ability of NT-Polyplex To Deliver a Suicide Gene to a Neuroblastoma Cell Line

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 637 KB

english, 2007

1325

952. Long-Term FVIII Expression Via Sleeping Beauty in Liver Sinusoidal Endothelial Cells of Transgenic Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 661 KB

english, 2007

1326

978. Superior Cardiac Transduction Efficacy Using a Pseudotyped AAV2/6 Vector Compared to a Heparin-Binding Site Deleted AAV2 in a Pig Model

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

1327

980. Delivery of VEGF Using AAV Vectors Promotes Functional Recovery of the Infarcted Myocardium by Sustaining Cardiomyocyte Contractility and Metabolism

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 607 KB

english, 2007

1328

981. Rapid Purification by FACS of Myoblasts Expressing Specific VEGF Levels Ensures Controlled Angiogenesis In Vivo

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2007

1329

999. AP20187-Mediated Activation of Ret Signalling as Regulated System for Neuroprotection in the Retina

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 632 KB

english, 2007

1330

1008. Influence of the Human and Murine CMV Enhancer on the Duration of Expression from CpG-Free pDNA Vectors in the Mouse Lung

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 632 KB

english, 2007

1331

1018. Generation of a CpG-Free Clinical Trial Plasmid for Cystic Fibrosis Lung Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 611 KB

english, 2007

1332

1024. Enhanced RNA Interference Using Reducible Poly(Amido Ethylenimine)

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 620 KB

english, 2007

1333

1033. Effect of Inhibition of CIITA by shRNA on High Responder Rat Orthotopic Liver Transplantation

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 477 KB

english, 2007

1334

1034. Preliminary Result of Injection of Progenitors of Hepatocytes Derived of Mesenchymal Stem Cell as Salvage Treatment for End-Stage Liver Disease - A Phase l/ll Clinical Trial

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1011 KB

english, 2007

1335

1035. Functional Characterization of Neural Stem Cells from a Murine Model of Globoid Cell Leukodystrophy: Relevance for the Development of Gene/Cell Therapy Approaches

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 573 KB

english, 2007

1336

1036. Effective Long-Term Transgene Expression by Self-Complementary Adeno-Associated Virus Serotypes to Human Mesenchymal Stem Cells Derived from Both Bone-Marrow and Umbilical-Cord Blood

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

1337

1040. Viral Vector-Mediated Expansion of Olfactory Ensheathing Glia for Spinal Cord Neuroregeneration

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 626 KB

english, 2007

1338

1041. Cell Density and Viral Vector Load Are Determinant Factors for Ex Vivo Lentiviral Transduction Efficiency of Hematopoietic Stem Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 626 KB

english, 2007

1339

1055. Infusion of Thymidine Kinase (TK)+ Donor Lymphocytes Promotes a Rapid and Wide Immune Reconstitution and Permits Long-Term Survival after Hematopoietic Transplantation from a Haploidentical Donor

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2007

1340

1058. In Vivo Lentiviral SIN-LTR Vector Integration Is Nearly Random and Shows a Preponderance of Satellite DNA in Postmitotic Rodent Eyes

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2007

1341

1070. Non-Viral Targeted Gene Transfer to Liver Cells

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 570 KB

english, 2007

1342

1074. Distinct Transduction Profiles in the Dystrophic Dogs with rAAV Serotype 8

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 624 KB

english, 2007

1343

1090. Prevention of Type I Diabetes Recurrence Following Islet Transplantation in Diabetic NOD Mice by Gene Therapy

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 625 KB

english, 2007

1344

1097. Transcriptionally Targeted Cancer Gene Therapy for Small Cell Lung Cancer

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 555 KB

english, 2007

1345

1099. Targeted Inactivation of the CCR5 Gene in Human Cells Using Peptide Nucleic Acids

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 611 KB

english, 2007

1346

Efficient Whole-body Transduction with Trans-splicing Adeno-associated Viral Vectors

Ghosh, Arkasubhra, Yue, Yongping, Long, Chun, Bostick, Brian, Duan, Dongsheng

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 43 KB

english, 2007

1347

DJ-1 and Parkin Modulate Dopamine-dependent Behavior and Inhibit MPTP-induced Nigral Dopamine Neuron Loss in Mice

Paterna, Jean-Charles, Leng, Andreas, Weber, Elisabeth, Feldon, Joram, Büeler, Hansruedi

Journal:

Molecular Therapy

Année:

2007

Fichier:

PDF, 36 KB

2007

1348

In This Issue

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 239 KB

english, 2007

1349

Happy Anniversary

Friedmann, Theodore

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 183 KB

english, 2007

1350

In This Issue

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 905 KB

english, 2007

1351

Research Highlights

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 310 KB

english, 2007

1352

In This Issue

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2007

1353

In This Issue

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2007

1354

Rapamycin-regulated Control of Antiangiogenic Tumor Therapy Following rAAV-mediated Gene Transfer

Nguyen, Minh, Huan-Tu, Guang, Gonzalez-Edick, Melissa, Rivera, Victor M, Clackson, Tim, Jooss, Karin U, Harding, Thomas C

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 363 KB

english, 2007

1355

Loss of Transgene following ex vivo Gene Transfer is Associated with a Dominant Th2 Response: Implications for Cutaneous Gene Therapy

Lu, Zhenmei, Ghazizadeh, Soosan

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 2.47 MB

english, 2007

1356

AAV and Insertional Mutagenesis

Williams, David A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 278 KB

english, 2007

1357

In This Issue

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2007

1358

Research Highlights

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 366 KB

english, 2007

1359

Research Highlights

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 441 KB

english, 2007

1360

AUTHOR INDEX

Journal:

Molecular Therapy

Année:

2007

Fichier:

PDF, 7.26 MB

2007

1361

Corrigendum to “Cellular Dynamics of EGF Receptor–targeted Synthetic Viruses”

de Bruin, Karla, Ruthardt, Nadia, von Gersdorff, Katharina, Bausinger, Ralf, Wagner, Ernst, Ogris, Manfred, Bräuchle, Christoph

Journal:

Molecular Therapy

Année:

2007

Fichier:

PDF, 36 KB

2007

1362

Research Highlights

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 540 KB

english, 2007

1363

In This Issue

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 730 KB

english, 2007

1364

Efficient Transduction of Simian Cells by HIV-1-based Lentiviral Vectors that Contain Mutations in the Capsid Protein

Rits, Maarten AN, van Dort, Karel A, Münk, Carsten, Meijer, Alexander B, Kootstra, Neeltje A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 406 KB

english, 2007

1365

Research Highlights

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 276 KB

english, 2007

1366

KEYWORD INDEX

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 4.56 MB

english, 2007

1367

Corrigendum to “Intranasal Administration of the Growth-compromised HSV-2 Vector ΔRR Prevents Kainate-induced Seizures and Neuronal Loss in Rats and Mice”

Laing, Jennifer M, Gober, Michael D, Golembewski, Erin K, Thompson, Scott M, Gyure, Kymberly A, Yarowsky, Paul J, Aurelian, Laure

Journal:

Molecular Therapy

Année:

2007

Fichier:

PDF, 114 KB

2007

1368

Apoptin studies illuminate intersection between lipidomics and tumor suppressors

Chada, Sunil, Ramesh, Rajagopal

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 274 KB

english, 2007

1369

Research Highlights

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 607 KB

english, 2007

1370

Research Highlights

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 614 KB

english, 2007

1371

Research Highlights

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 147 KB

english, 2007

1372

1. AAV Vector Integration at a Common Locus Leads to Hepatocellular Carcinoma in Mice

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 630 KB

english, 2007

1373

In This Issue

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2007

1374

Corrigendum to “Avian Influenza Virus Hemagglutinin Display on Baculovirus Envelope: Cytoplasmic Domain Affects Virus Properties and Vaccine Potential”

Yang, Ding-Gang, Chung, Yao-Chi, Lai, Yiu-Kay, Lai, Chia-Wei, Liu, Hung-Jen, Hu, Yu-Chen

Journal:

Molecular Therapy

Année:

2007

Fichier:

PDF, 70 KB

2007

1375

In This Issue

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 865 KB

english, 2007

1376

Research Highlights

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 524 KB

english, 2007

1377

Corrigendum to “Non-invasive Imaging in Gene Therapy”

Kristian Räty, Jani, Liimatainen, Timo, Unelma Kaikkonen, Minna, Gröhn, Olli, Juhani Airenne, Kari, Ylä-Herttuala, Seppo

Journal:

Molecular Therapy

Année:

2007

Fichier:

PDF, 34 KB

2007

1378

In This Issue

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 960 KB

english, 2007

1379

In This Issue

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 809 KB

english, 2007

1380

Of Mouse Models and Men

Williams, David A

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 121 KB

english, 2007

1381

Erratum to “Adhesion Receptors Mediate Efficient Non-viral Gene Delivery”

Zuhorn, Inge S, Kalicharan, Dharamdajal, Robillard, George T, Hoekstra, Dick

Journal:

Molecular Therapy

Année:

2007

Fichier:

PDF, 40 KB

2007

1382

Corrigendum to “Efficacy of Helper-dependent Adenovirus Vector-mediated Gene Therapy in Murine Glycogen Storage Disease Type Ia”

Koeberl, Dwight D, Sun, Baodong, Bird, Andrew, Chen, Yuan-Tsong, Oka, Kazuhiro, Chan, Lawrence

Journal:

Molecular Therapy

Année:

2007

Fichier:

PDF, 35 KB

2007

1383

Research Highlights

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 259 KB

english, 2007

1384

In This Issue

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2007