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1

Column chromatography and preparative TLC for isolation and purification of coumarins from Peucedanum verticillare L. Koch ex DC

Kozyra, Małgorzata, Głowniak, Kazimierz, Zabża, Andrzej, Zgórka, Grażyna, Mroczek, Tomasz, Cierpicki, Tomasz, Kulesza, Joanna, Mudło, Iwona

Journal:

JPC - Journal of Planar Chromatography - Modern TLC

Année:

2005

Langue:

english

Fichier:

PDF, 106 KB

english, 2005

2

Synthesis, conformation, and immunosuppressive activity of CLX and its analogues

P. Ruchala, B. Picur, M. Lisowski, T. Cierpicki, Z. Wieczorek, I.Z. Siemion

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 313 KB

english, 2003

3

NMR Solution Structure of the Integral Membrane Enzyme DsbB: Functional Insights into DsbB-Catalyzed Disulfide Bond Formation

Yunpeng Zhou, Tomasz Cierpicki, Ricardo H. Flores Jimenez, Stephen M. Lukasik, Jeffrey F. Ellena, David S. Cafiso, Hiroshi Kadokura, Jon Beckwith, John H. Bushweller

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 2.11 MB

english, 2008

4

Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia

Grembecka, Jolanta, He, Shihan, Shi, Aibin, Purohit, Trupta, Muntean, Andrew G, Sorenson, Roderick J, Showalter, Hollis D, Murai, Marcelo J, Belcher, Amalia M, Hartley, Thomas, Hess, Jay L, Cierpicki,

Journal:

Nature Chemical Biology

Année:

2012

Langue:

english

Fichier:

PDF, 2.41 MB

english, 2012

5

A Comparison of Australian and Singaporean Consumer Decision-Making Styles

Leo, Cheryl, Bennett, Rebekah, Cierpicki, Steven

Journal:

Journal of Customer Behaviour

Année:

2005

Langue:

english

Fichier:

PDF, 284 KB

english, 2005

6

Property focused structure-based optimization of small molecule inhibitors of the protein-protein interaction between menin and Mixed Lineage Leukemia (MLL)

Borkin, Dmitry, Pollock, Jonathan Wesley, Kempinska, Katarzyna, Purohit, Trupta, Li, Xiaoqin, Wen, Bo, Zhao, Ting, Miao, Hongzhi, Shukla, Shirish, He, Miao, Sun, Duxin, Cierpicki, Tomasz, Grembecka, J

Journal:

Journal of Medicinal Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 1.75 MB

english, 2016

7

Hydrolysis of the Phosphonamidate Bond in Phosphono Dipeptide Analogues — the Influence of the Nature of the N-Terminal Functional Group

Artur Mucha, Jolanta Grembecka, Tomasz Cierpicki, Paweł Kafarski

Journal:

European Journal of Organic Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 153 KB

english, 2003

8

1H NMR Studies of Aqueous Micellar Solutions of N-Dodecyl- N,N-dimethyl-N-benzylammonium Chloride

Bożenna Różycka-Roszak, Tomasz Cierpicki

Journal:

Journal of Colloid and Interface Science

Année:

1999

Langue:

english

Fichier:

PDF, 145 KB

english, 1999

9

Hydrogen Bonds in Human Ubiquitin Reflected in Temperature Coefficients of Amide Protons

Tomasz Cierpicki, Igor Zhukov, R.Andrew Byrd, Jacek Otlewski

Journal:

Journal of Magnetic Resonance

Année:

2002

Langue:

english

Fichier:

PDF, 79 KB

english, 2002

10

On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF

Meiying Zheng, Tomasz Cierpicki, Ko Momotani, Mykhaylo V Artamonov, Urszula Derewenda, John H Bushweller, Avril V Somlyo, Zygmunt S Derewenda

Journal:

BMC Structural Biology

Année:

2009

Langue:

english

Fichier:

PDF, 3.31 MB

english, 2009

11

The solution structure and dynamics of the DH-PH module of PDZRhoGEF in isolation and in complex with nucleotide-free RhoA

Tomasz Cierpicki, Jakub Bielnicki, Meiying Zheng, Jakub Gruszczyk, Marta Kasterka, Maxim Petoukhov, Aming Zhang, Erik J. Fernandez, Dmitri I. Svergun, Urszula Derewenda, John H. Bushweller, Zygmunt S.

Journal:

Protein Science

Année:

2009

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2009

12

The DC-module of doublecortin: Dynamics, domain boundaries, and functional implications

Tomasz Cierpicki, Myung Hee Kim, David R. Cooper, Urszula Derewenda, John H. Bushweller, Zygmunt S. Derewenda

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2006

Langue:

english

Fichier:

PDF, 363 KB

english, 2006

13

Canonical protein inhibitors of serine proteases

D. Krowarsch, T. Cierpicki, F. Jelen, J. Otlewski

Journal:

Cellular and Molecular Life Sciences

Année:

2003

Langue:

english

Fichier:

PDF, 544 KB

english, 2003

14

The DCX-domain tandems of doublecortin and doublecortin-like kinase

Kim, Myung Hee, Cierpicki, Tomasz, Derewenda, Urszula, Krowarsch, Daniel, Feng, Yuanyi, Devedjiev, Yancho, Dauter, Zbigniew, Walsh, Christopher A., Otlewski, Jacek, Bushweller, John H.

Journal:

Natural Structural Biology

Année:

2003

Langue:

english

Fichier:

PDF, 866 KB

english, 2003

15

Structure of the MLL CXXC domain–DNA complex and its functional role in MLL-AF9 leukemia

Cierpicki, Tomasz, Risner, Laurie E, Grembecka, Jolanta, Lukasik, Stephen M, Popovic, Relja, Omonkowska, Monika, Shultis, David D, Zeleznik-Le, Nancy J, Bushweller, John H

Journal:

Nature Structural and Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 834 KB

english, 2009

16

Amide proton temperature coefficients as hydrogen bond indicators in proteins

Tomasz Cierpicki, Jacek Otlewski

Journal:

Journal of Biomolecular NMR

Année:

2001

Langue:

english

Fichier:

PDF, 174 KB

english, 2001

17

Letter to the Editor: Assignment of1H,13C and15N resonances of the N-terminal microtubule-binding domain of human doublecortin

Tomasz Cierpicki, Myung Hee Kim, Jacek Otlewski, Zygmunt S. Derewenda, John H. Bushweller

Journal:

Journal of Biomolecular NMR

Année:

2003

Langue:

english

Fichier:

PDF, 49 KB

english, 2003

18

The Most Potent Organophosphorus Inhibitors of Leucine Aminopeptidase. Structure-Based Design, Chemistry, and Activity

Grembecka, Jolanta, Mucha, Artur, Cierpicki, Tomasz, Kafarski, Paweł

Journal:

Journal of Medicinal Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 272 KB

english, 2003

19

High resolution structure of the HDGF PWWP domain: A potential DNA binding domain

Stephen M. Lukasik, Tomasz Cierpicki, Matthew Borloz, Jolanta Grembecka, Allen Everett, John H. Bushweller

Journal:

Protein Science

Année:

2006

Langue:

english

Fichier:

PDF, 524 KB

english, 2006

20

NMR solution structure of Apis mellifera chymotrypsin/cathepsin G inhibitor-1 (AMCI-1): Structural similarity with Ascaris protease inhibitors

Tomasz Cierpicki, Jacek Bania, Jacek Otlewski

Journal:

Protein Science

Année:

2000

Langue:

english

Fichier:

PDF, 591 KB

english, 2000

21

Isolation And Structure Elucidation Of 5,7–disubstituted Simple Coumarins In The Fruits Of Heracleum Mantegazzianum

Glowniak, Kazimierz, Mroczek, Tomasz, Zabza, Andrzej, Cierpicki, Tomasz

Journal:

Pharmaceutical Biology

Année:

2000

Langue:

english

Fichier:

PDF, 102 KB

english, 2000

22

Structural Basis for Recognition of SMRT/N-CoR by the MYND Domain and Its Contribution to AML1/ETO's Activity

Yizhou Liu, Wei Chen, Justin Gaudet, Matthew D. Cheney, Liya Roudaia, Tomasz Cierpicki, Rachel C. Klet, Kari Hartman, Thomas M. Laue, Nancy A. Speck, John H. Bushweller

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2007

23

Probing the Supramodular Architecture of a Multidomain Protein: The Structure of Syntenin in Solution

Tomasz Cierpicki, John H. Bushweller, Zygmunt S. Derewenda

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 403 KB

english, 2005

24

Profiling the Dynamic Interfaces of Fluorinated Transcription Complexes for Ligand Discovery and Characterization

Pomerantz, William C., Wang, Ningkun, Lipinski, Ashley K., Wang, Rurun, Cierpicki, Tomasz, Mapp, Anna K.

Journal:

ACS Chemical Biology

Année:

2012

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2012

25

Structure-Based Design of Novel Benzoxazinorifamycins with Potent Binding Affinity to Wild-Type and Rifampin-Resistant Mutant Mycobacterium tuberculosis RNA Polymerases

Gill, Sumandeep K., Xu, Hao, Kirchhoff, Paul D., Cierpicki, Tomasz, Turbiak, Anjanette J., Wan, Baojie, Zhang, Nan, Peng, Kuan-Wei, Franzblau, Scott G., Garcia, George A.

Journal:

Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 467 KB

english, 2012

26

Determination of a high precision structure of a novel protein, Linum usitatissimum trypsin inhibitor (LUTI), using computer-aided assignment of NOESY cross-peaks

Tomasz Cierpicki, Jacek Otlewski

Journal:

Journal of Molecular Biology

Année:

2000

Langue:

english

Fichier:

PDF, 431 KB

english, 2000

27

The Dimerization Mechanism of LIS1 and its Implication for Proteins Containing the LisH Motif

Agnieszka Mateja, Tomasz Cierpicki, Marcin Paduch, Zygmunt S. Derewenda, Jacek Otlewski

Journal:

Journal of Molecular Biology

Année:

2006

Langue:

english

Fichier:

PDF, 499 KB

english, 2006

28

Structure of the AML1-ETO NHR3–PKA(RIIα) Complex and Its Contribution to AML1-ETO Activity

Takeshi Corpora, Liya Roudaia, Zaw Min Oo, Wei Chen, Ekaterina Manuylova, Xiongwei Cai, Michael J. Chen, Tomasz Cierpicki, Nancy A. Speck, John H. Bushweller

Journal:

Journal of Molecular Biology

Année:

2010

Langue:

english

Fichier:

PDF, 2.17 MB

english, 2010

29

Structural Features and Chaperone Activity of the NudC Protein Family

Meiying Zheng, Tomasz Cierpicki, Alexander J. Burdette, Darkhan Utepbergenov, Paweł Ł. Janczyk, Urszula Derewenda, P. Todd Stukenberg, Kim A. Caldwell, Zygmunt S. Derewenda

Journal:

Journal of Molecular Biology

Année:

2011

Langue:

english

Fichier:

PDF, 2.15 MB

english, 2011

30

NMR Structures of Two Variants of Bovine Pancreatic Trypsin Inhibitor (BPTI) Reveal Unexpected Influence of Mutations on Protein Structure and Stability

Tomasz Cierpicki, Jacek Otlewski

Journal:

Journal of Molecular Biology

Année:

2002

Langue:

english

Fichier:

PDF, 342 KB

english, 2002

31

Convergence of the ZMIZ1 and NOTCH1 Pathways at C-MYC in Acute T Lymphoblastic Leukemias

Rakowski, L. A., Garagiola, D. D., Li, C. M., Decker, M., Caruso, S., Jones, M., Kuick, R., Cierpicki, T., Maillard, I., Chiang, M. Y.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.97 MB

english, 2013

32

Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia

Shi, A., Murai, M. J., He, S., Lund, G., Hartley, T., Purohit, T., Reddy, G., Chruszcz, M., Grembecka, J., Cierpicki, T.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 573 KB

english, 2012

33

Leukemia Fusion Target AF9 Is an Intrinsically Disordered Transcriptional Regulator that Recruits Multiple Partners via Coupled Folding and Binding

Leach, Benjamin I., Kuntimaddi, Aravinda, Schmidt, Charles R., Cierpicki, Tomasz, Johnson, Stephanie A., Bushweller, John H.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2013

34

Molecular Basis of the Mixed Lineage Leukemia-Menin Interaction: IMPLICATIONS FOR TARGETING MIXED LINEAGE LEUKEMIAS

Grembecka, J., Belcher, A. M., Hartley, T., Cierpicki, T.

Journal:

Journal of Biological Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 1.85 MB

english, 2010

35

Detection of disordered regions in globular proteins using 13 C-detected NMR

Gray, Felicia L. V., Murai, Marcelo J., Grembecka, Jolanta, Cierpicki, Tomasz

Journal:

Protein Science

Année:

2012

Langue:

english

Fichier:

PDF, 417 KB

english, 2012

36

Importance of α–helix N–capping motif in stabilization of ββα fold

Katarzyna Koscielska-Kasprzak, Tomasz Cierpicki, Jacek Otlewski

Journal:

Protein Science

Année:

2003

Langue:

english

Fichier:

PDF, 222 KB

english, 2003

37

A Novel Small-Molecule Inhibitor of Mcl-1 Blocks Pancreatic Cancer Growth In Vitro and In Vivo

Abulwerdi, F., Liao, C., Liu, M., Azmi, A. S., Aboukameel, A., Mady, A. S. A., Gulappa, T., Cierpicki, T., Owens, S., Zhang, T., Sun, D., Stuckey, J. A., Mohammad, R. M., Nikolovska-Coleska, Z.

Journal:

Molecular Cancer Therapeutics

Année:

2014

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2014

38

Dysregulated Hematopoiesis Caused by Mammary Cancer Is Associated with Epigenetic Changes and Hox Gene Expression in Hematopoietic Cells

Sio, A., Chehal, M. K., Tsai, K., Fan, X., Roberts, M. E., Nelson, B. H., Grembecka, J., Cierpicki, T., Krebs, D. L., Harder, K. W.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2013

39

Challenges and opportunities in targeting the menin–MLL interaction

Cierpicki, Tomasz, Grembecka, Jolanta

Journal:

Future Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 3.10 MB

english, 2014

40

Charged Gels as Orienting Media for Measurement of Residual Dipolar Couplings in Soluble and Integral Membrane Proteins

Cierpicki, Tomasz, Bushweller, John H.

Journal:

Journal of the American Chemical Society

Année:

2004

Langue:

english

Fichier:

PDF, 169 KB

english, 2004

41

High-Affinity Small-Molecule Inhibitors of the Menin-Mixed Lineage Leukemia (MLL) Interaction Closely Mimic a Natural Protein–Protein Interaction

He, Shihan, Senter, Timothy J., Pollock, Jonathan, Han, Changho, Upadhyay, Sunil Kumar, Purohit, Trupta, Gogliotti, Rocco D., Lindsley, Craig W., Cierpicki, Tomasz, Stauffer, Shaun R., Grembecka, Jola

Journal:

Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 5.59 MB

english, 2014

42

The Binding of the PDZ Tandem of Syntenin to Target Proteins †,‡

Grembecka, Jolanta, Cierpicki, Tomasz, Devedjiev, Yancho, Derewenda, Urszula, Kang, Beom Sik, Bushweller, John H., Derewenda, Zygmunt S.

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 727 KB

english, 2006

43

Structure-Based Design and Synthesis of Dipeptide Analogues as New Inhibitors of Leucine Aminopeptidase

Grembecka, Jolanta, Mucha, Artur, Cierpicki, Tomasz, Kafarski, Paweł

Journal:

Phosphorus Sulfur and Silicon and the Related Elements

Année:

2002

Langue:

english

Fichier:

PDF, 91 KB

english, 2002

44

Synthesis of Triethyl N-Formyl-N-phosphonomethylglycinate and Diethyl N-Formyl-N-phosphonomethylglycine and Studies of Their Rotational Conformers by Dynamic NMR

Ziora, Zyta, Cierpicki, Tomasz, Grembecka, Jolanta, Kafarski, Paweł

Journal:

Journal of Chemical Research

Année:

1999

Langue:

english

Fichier:

PDF, 85 KB

english, 1999

45

Increasing the Accuracy of Solution NMR Structures of Membrane Proteins by Application of Residual Dipolar Couplings. High-Resolution Structure of Outer Membrane Protein A

Cierpicki, Tomasz, Liang, Binyong, Tamm, Lukas K., Bushweller, John H.

Journal:

Journal of the American Chemical Society

Année:

2006

Langue:

english

Fichier:

PDF, 309 KB

english, 2006

46

3-Substituted- N -(4-Hydroxynaphthalen-1-yl)arylsulfonamides as a Novel Class of Selective Mcl-1 Inhibitors: Structure-Based Design, Synthesis, SAR, and Biological Evaluation

Abulwerdi, Fardokht A., Liao, Chenzhong, Mady, Ahmed S., Gavin, Jordan, Shen, Chenxi, Cierpicki, Tomasz, Stuckey, Jeanne A., Showalter, H. D. Hollis, Nikolovska-Coleska, Zaneta

Journal:

Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 8.26 MB

english, 2014

47

Inhibition of CDC25B Phosphatase Through Disruption of Protein–Protein Interaction

Lund, George, Dudkin, Sergii, Borkin, Dmitry, Ni, Wendi, Grembecka, Jolanta, Cierpicki, Tomasz

Journal:

ACS Chemical Biology

Année:

2015

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2015

48

Solution NMR studies reveal no global flexibility in the catalytic domain of CDC25B

Lund, George, Cierpicki, Tomasz

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2014

Langue:

english

Fichier:

PDF, 337 KB

english, 2014

49

Targeting protein-protein interactions in hematologic malignancies: still a challenge or a great opportunity for future therapies?

Cierpicki, Tomasz, Grembecka, Jolanta

Journal:

Immunological Reviews

Année:

2015

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2015

50

Crystal Structure of Menin Reveals Binding Site for Mixed Lineage Leukemia (MLL) Protein

Murai, M. J., Chruszcz, M., Reddy, G., Grembecka, J., Cierpicki, T.

Journal:

Journal of Biological Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 2.35 MB

english, 2011