Volume 33; Issue 9

Drug Metabolism and Disposition

Volume 33; Issue 9

1

A UNIFIED MODEL FOR PREDICTING HUMAN HEPATIC, METABOLIC CLEARANCE FROM IN VITRO INTRINSIC CLEARANCE DATA IN HEPATOCYTES AND MICROSOMES

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 397 KB

english, 2005

2

SULFONATION OF ENVIRONMENTAL CHEMICALS AND THEIR METABOLITES IN THE POLAR BEAR (Ursus maritimus)

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 310 KB

english, 2005

3

A NOVEL MODEL FOR PREDICTION OF HUMAN DRUG CLEARANCE BY ALLOMETRIC SCALING

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 288 KB

english, 2005

4

ENANTIOSELECTIVE METABOLISM AND CYTOTOXICITY OF R-IFOSFAMIDE AND S-IFOSFAMIDE BY TUMOR CELL-EXPRESSED CYTOCHROMES P450

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 271 KB

english, 2005

5

EFFECT OF CYP2D6*10 ALLELE ON THE PHARMACOKINETICS OF LORATADINE IN CHINESE SUBJECTS

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 174 KB

english, 2005

6

ACCURACY OF ALLOMETRICALLY PREDICTED PHARMACOKINETIC PARAMETERS IN HUMANS: ROLE OF SPECIES SELECTION

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 177 KB

english, 2005

7

ISOFORM-SPECIFIC EXPRESSION AND INDUCTION OF UDP-GLUCURONOSYLTRANSFERASE IN IMMUNOACTIVATED PERITONEAL MACROPHAGES OF THE RAT

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 467 KB

english, 2005

8

CYP2A6 IS A PRINCIPAL ENZYME INVOLVED IN HYDROXYLATION OF 1,7-DIMETHYLXANTHINE, A MAIN CAFFEINE METABOLITE, IN HUMANS

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 280 KB

english, 2005

9

CANALICULAR AND SINUSOIDAL DISPOSITION OF BILIRUBIN MONO- AND DIGLUCURONIDES IN SANDWICH-CULTURED HUMAN AND RAT PRIMARY HEPATOCYTES

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 232 KB

english, 2005

10

BIMOLECULAR FLUORESCENCE COMPLEMENTATION ANALYSIS OF CYTOCHROME P450 2C2, 2E1, AND NADPH-CYTOCHROME P450 REDUCTASE MOLECULAR INTERACTIONS IN LIVING CELLS

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 679 KB

english, 2005

11

METABOLISM AND DISPOSITION OF A POTENT GROUP II METABOTROPIC GLUTAMATE RECEPTOR AGONIST, IN RATS, DOGS, AND MONKEYS

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 380 KB

english, 2005

12

UDP-GLUCURONOSYLTRANSFERASE 2B7 IS THE MAJOR ENZYME RESPONSIBLE FOR GEMCABENE GLUCURONIDATION IN HUMAN LIVER MICROSOMES

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 279 KB

english, 2005

13

A MATHEMATICAL DESCRIPTION OF THE FUNCTIONALITY OF CORRECTION FACTORS USED IN ALLOMETRY FOR PREDICTING HUMAN DRUG CLEARANCE

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 88 KB

english, 2005

14

REGULATION OF MOUSE ORGANIC ANION-TRANSPORTING POLYPEPTIDES (OATPS) IN LIVER BY PROTOTYPICAL MICROSOMAL ENZYME INDUCERS THAT ACTIVATE DISTINCT TRANSCRIPTION FACTOR PATHWAYS

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 342 KB

english, 2005

15

POPULATION PHARMACOKINETICS OF CYCLOSPORINE IN CLINICAL RENAL TRANSPLANT PATIENTS

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 442 KB

english, 2005

16

METABOLISM OF THE ONE-RING OPEN METABOLITES OF THE CARDIOPROTECTIVE DRUG DEXRAZOXANE TO ITS ACTIVE METAL-CHELATING FORM IN THE RAT

Schroeder, P. E.

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 187 KB

english, 2005

17

INVOLVEMENT OF MOLYBDENUM HYDROXYLASES IN REDUCTIVE METABOLISM OF NITRO POLYCYCLIC AROMATIC HYDROCARBONS IN MAMMALIAN SKIN

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 343 KB

english, 2005

18

QUANTITATIVE ANALYSIS OF CYTOCHROME P450 ISOZYMES BY MEANS OF UNIQUE ISOZYME-SPECIFIC TRYPTIC PEPTIDES: A PROTEOMIC APPROACH

Alterman, M. A.

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 464 KB

english, 2005

19

DIRECT DETERMINATION OF UNBOUND INTRINSIC DRUG CLEARANCE IN THE MICROSOMAL STABILITY ASSAY

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 206 KB

english, 2005

20

EXPRESSION OF HUMAN PHASE II ENZYMES IN CHIMERIC MICE WITH HUMANIZED LIVER

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 411 KB

english, 2005

21

THE USE OF SANDWICH-CULTURED RAT HEPATOCYTES TO DETERMINE THE INTRINSIC CLEARANCE OF COMPOUNDS WITH DIFFERENT EXTRACTION RATIOS: 7-ETHOXYCOUMARIN AND WARFARIN

Journal:

Drug Metabolism and Disposition

Année:

2005

Langue:

english

Fichier:

PDF, 265 KB

english, 2005