Volume 5; Issue 4

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Clinical Pharmacology in Drug Development
Volume 5; Issue 4

Clinical Pharmacology in Drug Development

Volume 5; Issue 4

1

A Phase 1 Dose-Escalation Study of ASP2409, a Selective T-Cell Costimulation Inhibitor, in Stable Rheumatoid Arthritis Patients on Methotrexate Therapy

Zhang, Wenhui, Kernstock, Robert M., Karrer, Erik E., Cohen, Stanley B., Chindalore, Vishala L., Kivitz, Alan J., Blahunka, Paul C., Delgado-Herrera, Leticia, Zeiher, Bernhardt G., Samberg, Nancy L.,

Journal:

Clinical Pharmacology in Drug Development

Année:

2016

Langue:

english

Fichier:

PDF, 325 KB

english, 2016

2

A Pharmacokinetic Study Comparing Eslicarbazepine Acetate Administered Orally as a Crushed or Intact Tablet in Healthy Volunteers

Sunkaraneni, Soujanya, Kharidia, Jahnavi, Schutz, Ralph, Blum, David, Cheng, Hailong

Journal:

Clinical Pharmacology in Drug Development

Année:

2016

Langue:

english

Fichier:

PDF, 308 KB

english, 2016

3

Lung Delivery of Indacaterol and Mometasone Furoate Following Inhalation of QMF149 in Healthy Volunteers

Vaidya, Soniya S., Khindri, Sanjeev, Maahs, Suzanne, Machineni, Surendra, Hara, Hisanori, Juan, Axel, Kaiser, Günther

Journal:

Clinical Pharmacology in Drug Development

Année:

2016

Langue:

english

Fichier:

PDF, 410 KB

english, 2016

4

Drug-Drug Interaction of Omeprazole With the HCV Direct-Acting Antiviral Agents Paritaprevir/Ritonavir and Ombitasvir With and Without Dasabuvir

Polepally, Akshanth R., Dutta, Sandeep, Hu, Beibei, Podsadecki, Thomas J., Awni, Walid M., Menon, Rajeev M.

Journal:

Clinical Pharmacology in Drug Development

Année:

2016

Langue:

english

Fichier:

PDF, 575 KB

english, 2016

5

Phase IA Clinical Trial Evaluating the Tolerability, Pharmacokinetics, and Analgesic Efficacy of an Intrathecally Administered Neurotensin A Analogue in Central Neuropathic Pain Following Spinal Cord Injury

Sang, Christine N., Barnabe, Kate J., Kern, Steven E.

Journal:

Clinical Pharmacology in Drug Development

Année:

2016

Langue:

english

Fichier:

PDF, 770 KB

english, 2016

6

Compelling Relationship of CYP3A Induction to Levels of the Putative Biomarker 4β-Hydroxycholesterol and Changes in Midazolam Exposure

Mangold, James B., Wu, Fan, Rebello, Sam

Journal:

Clinical Pharmacology in Drug Development

Année:

2016

Langue:

english

Fichier:

PDF, 142 KB

english, 2016

7

Issue Information

Journal:

Clinical Pharmacology in Drug Development

Année:

2016

Langue:

english

Fichier:

PDF, 405 KB

english, 2016

8

Phase 1 Study of Safety, Tolerability, and Pharmacokinetics of PTC299, an Inhibitor of Stress-Regulated Protein Translation

Weetall, Marla, Davis, Thomas, Elfring, Gary, Northcutt, Valerie, Cao, Liangxian, Moon, Young-Choon, Riebling, Peter, Dali, Mandar, Hirawat, Samit, Babiak, John, Colacino, Joseph, Almstead, Neil, Spie

Journal:

Clinical Pharmacology in Drug Development

Année:

2016

Langue:

english

Fichier:

PDF, 661 KB

english, 2016

9

A First-in-Patient, Multicenter, Double-Blind, 2-Arm, Placebo-Controlled, Randomized Safety and Tolerability Study of a Novel Oral Drug Candidate, CTP-499, in Chronic Kidney Disease

Sabounjian, LuAnn, Graham, Philip, Wu, Lijun, Braman, Virginia, Cheng, Changfu, Liu, Julie, Shipley, James, Neutel, Joel, Dao, Michael

Journal:

Clinical Pharmacology in Drug Development

Année:

2016

Langue:

english

Fichier:

PDF, 701 KB

english, 2016

10

Pharmacokinetics, Safety, and Tolerability of Fevipiprant (QAW039), a Novel CRTh2 Receptor Antagonist: Results From 2 Randomized, Phase 1, Placebo-Controlled Studies in Healthy Volunteers

Erpenbeck, Veit J., Vets, Eva, Gheyle, Lien, Osuntokun, Wande, Larbig, Michael, Neelakantham, Srikanth, Sandham, David, Dubois, Gerald, Elbast, Walid, Goldsmith, Paul, Weiss, Markus

Journal:

Clinical Pharmacology in Drug Development

Année:

2016

Langue:

english

Fichier:

PDF, 265 KB

english, 2016

11

10.1002/cpdd.v5.4

Journal:

Clinical Pharmacology in Drug Development

Fichier:

PDF, 3.54 MB