Volume 14; Issue 5

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Chemistry & Biology
Volume 14; Issue 5

Chemistry & Biology

Volume 14; Issue 5

1

Design, Synthesis, and Evaluation of In Vivo Potency and Selectivity of Epoxysuccinyl-Based Inhibitors of Papain-Family Cysteine Proteases

Amir Masoud Sadaghiani, Steven H.L. Verhelst, Vasilena Gocheva, Kimberly Hill, Eva Majerova, Sherman Stinson, Johanna A. Joyce, Matthew Bogyo

Journal:

Chemistry & Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2007

2

Molecular Similarity Analysis Uncovers Heterogeneous Structure-Activity Relationships and Variable Activity Landscapes

Lisa Peltason, Jürgen Bajorath

Journal:

Chemistry & Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2007

3

An Unusual Mode of DNA Duplex Association: Watson-Crick Interaction of All-Purine Deoxyribonucleic Acids

Thomas R. Battersby, Maria Albalos, Michel J. Friesenhahn

Journal:

Chemistry & Biology

Année:

2007

Langue:

english

Fichier:

PDF, 386 KB

english, 2007

4

Alkyl-CoA Disulfides as Inhibitors and Mechanistic Probes for FabH Enzymes

Mamoun M. Alhamadsheh, Faik Musayev, Andrey A. Komissarov, Sarbjot Sachdeva, H. Tonie Wright, Neel Scarsdale, Galina Florova, Kevin A. Reynolds

Journal:

Chemistry & Biology

Année:

2007

Langue:

english

Fichier:

PDF, 612 KB

english, 2007

5

Structures of Clostridium botulinum Neurotoxin Serotype A Light Chain Complexed with Small-Molecule Inhibitors Highlight Active-Site Flexibility

Nicholas R. Silvaggi, Grant E. Boldt, Mark S. Hixon, Jack P. Kennedy, Saul Tzipori, Kim D. Janda, Karen N. Allen

Journal:

Chemistry & Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2007

6

Structure of Saccharomyces cerevisiae Chitinase 1 and Screening-Based Discovery of Potent Inhibitors

Ramon Hurtado-Guerrero, Daan M.F. van Aalten

Journal:

Chemistry & Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2007

7

Effects of Photochemically Activated Alkylating Agents of the FR900482 Family on Chromatin

Vidya Subramanian, Pascal Ducept, Robert M. Williams, Karolin Luger

Journal:

Chemistry & Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.30 MB

english, 2007

8

Identification of a Type III Thioesterase Reveals the Function of an Operon Crucial for Mtb Virulence

Feng Wang, Robert Langley, Gulcin Gulten, Lei Wang, James C. Sacchettini

Journal:

Chemistry & Biology

Année:

2007

Langue:

english

Fichier:

PDF, 756 KB

english, 2007

9

Biosynthesis and Structure of Aeruginoside 126A and 126B, Cyanobacterial Peptide Glycosides Bearing a 2-Carboxy-6-Hydroxyoctahydroindole Moiety

Keishi Ishida, Guntram Christiansen, Wesley Y. Yoshida, Rainer Kurmayer, Martin Welker, Nativitat Valls, Josep Bonjoch, Christian Hertweck, Thomas Börner, Thomas Hemscheidt, Elke Dittmann

Journal:

Chemistry & Biology

Année:

2007

Langue:

english

Fichier:

PDF, 560 KB

english, 2007

10

Control of Oxygenation in Lipoxygenase and Cyclooxygenase Catalysis

Claus Schneider, Derek A. Pratt, Ned A. Porter, Alan R. Brash

Journal:

Chemistry & Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2007

11

Structure-Activity-Based Design of a Synthetic Malaria Peptide Eliciting Sporozoite Inhibitory Antibodies in a Virosomal Formulation

Shinji L. Okitsu, Ursula Kienzl, Kerstin Moehle, Olivier Silvie, Elisabetta Peduzzi, Markus S. Mueller, Robert W. Sauerwein, Hugues Matile, Rinaldo Zurbriggen, Dominique Mazier, John A. Robinson, Gerd

Journal:

Chemistry & Biology

Année:

2007

Langue:

english

Fichier:

PDF, 838 KB

english, 2007

12

DNA Made of Purines Only

Christoph Arenz, Oliver Seitz

Journal:

Chemistry & Biology

Année:

2007

Langue:

english

Fichier:

PDF, 239 KB

english, 2007

13

Exploiting Green Treasures

Stephanie Grond, Guido Meurer

Journal:

Chemistry & Biology

Année:

2007

Langue:

english

Fichier:

PDF, 83 KB

english, 2007

14

Neuropathic Pain Treatment Gives Avigen New Lease on Life and Neuromed Follows the Snail Trail

Journal:

Chemistry & Biology

Année:

2007

Fichier:

PDF, 30 KB

2007