Volume 85; Issue 2

Chemical Biology & Drug Design

Volume 85; Issue 2

1

Targeting Dormant Tuberculosis Bacilli: Results for Molecules with a Novel Pyrimidone Scaffold

Joshi, Rohit R., Barchha, Avinash, Khedkar, Vijay M., Pissurlenkar, Raghuvir R. S., Sarkar, Sampa, Sarkar, Dhiman, Joshi, Rohini R., Joshi, Ramesh A., Shah, Anamik K., Coutinho, Evans C.

Journal:

Chemical Biology & Drug Design

Année:

2015

Langue:

english

Fichier:

PDF, 368 KB

english, 2015

2

Hologram Quantitative Structure Activity Relationship, Docking, and Molecular Dynamics Studies of Inhibitors for CXCR4

Zhang, Chongqian, Du, Chunmiao, Feng, Zhiwei, Zhu, Jingyu, Li, Youyong

Journal:

Chemical Biology & Drug Design

Année:

2015

Langue:

english

Fichier:

PDF, 669 KB

english, 2015

3

Synthesis and Evaluation of a New Series of 3,5-bis((5-bromo-6-methyl-2- t -aminopyrimidin-4-yl)thio)-4 H -1,2,4-triazol-4-amines and their Cyclized Products ‘Pyrimidinylthio Pyrimidotriazolothiadiazines’ as 15- Lipo-Oxygenase Inhibitors

Asghari, Tayebe, Bakavoli, Mehdi, Rahimizadeh, Mohammad, Eshghi, Hossein, Saberi, Sattar, Karimian, Azam, Hadizadeh, Farzin, Ghandadi, Moreteza

Journal:

Chemical Biology & Drug Design

Année:

2015

Langue:

english

Fichier:

PDF, 629 KB

english, 2015

4

Design, Synthesis and Evaluation of Rhodanine Derivatives as Aldose Reductase Inhibitors

Agrawal, Yogesh P., Agrawal, Mona Y., Gupta, Arun K.

Journal:

Chemical Biology & Drug Design

Année:

2015

Langue:

english

Fichier:

PDF, 443 KB

english, 2015

5

Discovery of Novel 17-Phenylethylaminegeldanamycin Derivatives as Potent Hsp90 Inhibitors

Li, Zhenyu, Jia, Lejiao, Wang, Jifeng, Wu, Xingkang, Shi, Guowei, Lu, Chunhua, Shen, Yuemao

Journal:

Chemical Biology & Drug Design

Année:

2015

Langue:

english

Fichier:

PDF, 439 KB

english, 2015

6

Drug Repurposing Based on Drug-Drug Interaction

Zhou, Bin, Wang, Rong, Wu, Ping, Kong, De-Xin

Journal:

Chemical Biology & Drug Design

Année:

2015

Langue:

english

Fichier:

PDF, 800 KB

english, 2015

7

2-(Hetero(aryl)methylene)hydrazine-1-carbothioamides as Potent Urease Inhibitors

Saeed, Aamer, Imran, Aqeel, Channar, Pervaiz A., Shahid, Mohammad, Mahmood, Wajahat, Iqbal, Jamshed

Journal:

Chemical Biology & Drug Design

Année:

2015

Langue:

english

Fichier:

PDF, 552 KB

english, 2015

8

Discovery, Optimization, and Pharmacophore Modeling of Oleanolic Acid and Analogues as Breast Cancer Cell Migration and Invasion Inhibitors Through Targeting Brk/Paxillin/Rac1 Axis

Elsayed, Heba E., Akl, Mohamed R., Ebrahim, Hassan Y., Sallam, Asmaa A., Haggag, Eman G., Kamal, Amel M., El Sayed, Khalid A.

Journal:

Chemical Biology & Drug Design

Année:

2015

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2015

9

Comparative Analysis of Various Electrostatic Potentials on Docking Precision Against Cyclin-Dependent Kinase 2 Protein: A Multiple Docking Approach

Tripathi, Sunil K., Soundarya, Rajendran Naga, Singh, Poonam, Singh, Sanjeev K.

Journal:

Chemical Biology & Drug Design

Année:

2015

Langue:

english

Fichier:

PDF, 547 KB

english, 2015

10

Highly Potential Antiplasmodial Restricted Peptides

Marcelo Der Torossian, Torres, Silva, Adriana F., Alves, Flávio L., Capurro, Margareth L., Miranda, Antonio, Vani Xavier, Oliveira

Journal:

Chemical Biology & Drug Design

Année:

2015

Langue:

english

Fichier:

PDF, 721 KB

english, 2015

11

Computer-Aided Drug Discovery Approach Finds Calcium Sensitizer of Cardiac Troponin

Lindert, Steffen, Li, Monica X., Sykes, Brian D., McCammon, J. Andrew

Journal:

Chemical Biology & Drug Design

Année:

2015

Langue:

english

Fichier:

PDF, 998 KB

english, 2015

12

The Potential Roles of Cell Surface pHs in Bioactive Peptide Activation

Chen, Long, Liang, Jun F.

Journal:

Chemical Biology & Drug Design

Année:

2015

Langue:

english

Fichier:

PDF, 936 KB

english, 2015

13

Structural Basis for Low-Affinity Binding of Non-R2 Carboxylate-Substituted Tricyclic Quinoline Analogs to CK2α: Comparative Molecular Dynamics Simulation Studies

Zhou, Yue, Li, Xitao, Zhang, Na, Zhong, Rugang

Journal:

Chemical Biology & Drug Design

Année:

2015

Langue:

english

Fichier:

PDF, 2.03 MB

english, 2015

14

Hybrid Molecule from Farnesylthiosalicylic Acid-diamine and Phenylpropenoic Acid as Ras-related Signaling Inhibitor with Potent Antitumor Activities

Ling, Yong, Wang, Zhiqiang, Wang, Xuemin, Li, Xianghua, Wang, Xinyang, Zhang, Wei, Dai, Hong, Chen, Li, Zhang, Yihua

Journal:

Chemical Biology & Drug Design

Année:

2015

Langue:

english

Fichier:

PDF, 1010 KB

english, 2015

15

Issue Information

Journal:

Chemical Biology & Drug Design

Année:

2015

Langue:

english

Fichier:

PDF, 385 KB

english, 2015

16

Positional Isomerization of A Non-Cleavable Combi-Molecule Dramatically Altered Tumor Cell Response Profile

Huang, Ying, Rachid, Zakaria, Peyrard, Lisa, Senhaji Mouhri, Zhor, Williams, Christopher, Jean-Claude, Bertrand J.

Journal:

Chemical Biology & Drug Design

Année:

2015

Langue:

english

Fichier:

PDF, 1.30 MB

english, 2015