Volume 81; Issue 2

Chemical Biology & Drug Design

Volume 81; Issue 2

1

Molecular Modeling of a Phenyl-Amidine Class of NMDA Receptor Antagonists and the Rational Design of New Triazolyl-Amidine Derivatives

Abreu, Paula A., Castro, Helena C., Paes-de-Carvalho, Roberto, Rodrigues, Carlos R., Giongo, Viveca, Paixão, Izabel C. N. P., Santana, Marcos V., Ferreira, Jainne M., Caversan, Octavia M., Leão, Raque

Journal:

Chemical Biology & Drug Design

Année:

2013

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2013

2

New Alloferon Analogues: Synthesis and Antiviral Properties

Kuczer, Mariola, Majewska, Anna, Zahorska, Renata

Journal:

Chemical Biology & Drug Design

Année:

2013

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2013

3

Issue Information

Journal:

Chemical Biology & Drug Design

Année:

2013

Langue:

english

Fichier:

PDF, 342 KB

english, 2013

4

Design, Synthesis, Structure-Activity Relationships, and Docking Studies of 1-(γ-1,2,3-Triazol Substituted Prolyl)-( S )-3,3-Difluoropyrrolidines as a Novel Series of Potent and Selective Dipeptidyl Peptidase-4 Inhibitors

Zhang, Lei, Su, Mingbo, Li, Jingya, Ji, Xun, Wang, Jiang, Li, Zeng, Li, Jia, Liu, Hong

Journal:

Chemical Biology & Drug Design

Année:

2013

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2013

5

Comparison of the Molecular Dynamics and Calculated Binding Free Energies for Nine FDA-Approved HIV-1 PR Drugs Against Subtype B and C-SA HIV PR

Ahmed, Shaimaa M., Kruger, Hendrik G., Govender, Thirumala, Maguire, Glenn E. M., Sayed, Yasien, Ibrahim, Mahmoud A. A., Naicker, Previn, Soliman, Mahmoud E. S.

Journal:

Chemical Biology & Drug Design

Année:

2013

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2013

6

Synthesis and Antitubercular Activity of 2-(substituted phenyl/benzyl-amino)-6-(4-chlorophenyl)-5-(methoxycarbonyl)-4-methyl-3,6-dihydropyrimidin-1-ium Chlorides

Narayanaswamy, Venugopala K., Nayak, Susanta K., Pillay, Melendhran, Prasanna, Renuka, Coovadia, Yacoob M., Odhav, Bharti

Journal:

Chemical Biology & Drug Design

Année:

2013

Langue:

english

Fichier:

PDF, 976 KB

english, 2013

7

Effects of Flavone Derivatives on Antigen-Stimulated Degranulation in RBL-2H3 Cells

Hwang, Doseok, Park, Hye-Jin, Seo, Eun-Kyung, Oh, Joo Y., Ji, Sang Y., Park, Dong K., Lim, Yoongho

Journal:

Chemical Biology & Drug Design

Année:

2013

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2013

8

Structure-Based Design and Synthesis of Benzothiazole Phosphonate Analogues with Inhibitors of Human ABAD-Aβ for Treatment of Alzheimer’s Disease

Valasani, Koteswara R., Hu, Gang, Chaney, Michael O., Yan, Shirley S.

Journal:

Chemical Biology & Drug Design

Année:

2013

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2013

9

Structure-Based Identification of Aporphines with Selective 5-HT 2A Receptor-Binding Activity

Munusamy, Vani, Yap, Beow Keat, Buckle, Michael J. C., Doughty, Stephen W., Chung, Lip Yong

Journal:

Chemical Biology & Drug Design

Année:

2013

Langue:

english

Fichier:

PDF, 638 KB

english, 2013

10

Synthesis and Evaluation of Thiouracil Derivatives as Dipeptidyl Peptidase IV Inhibitors

Sharma, Mani, Singh, Divya, Gupta, Monica

Journal:

Chemical Biology & Drug Design

Année:

2013

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2013

11

A New Approach to Counteract Bacteria Resistance: A Comparative Study Between Moxifloxacin and a New Moxifloxacin Derivative in Different Model Systems of Bacterial Membrane

Lopes, Silvia C., Ribeiro, Carla, Gameiro, Paula

Journal:

Chemical Biology & Drug Design

Année:

2013

Langue:

english

Fichier:

PDF, 759 KB

english, 2013

12

Design, Synthesis and Biological Evaluation of Cinnamic Acyl Shikonin Derivatives

Lin, Hong-Yan, Chen, Wei, Shi, Jing, Kong, Wen-Yao, Qi, Jin-Liang, Wang, Xiao-Ming, Yang, Yong-Hua

Journal:

Chemical Biology & Drug Design

Année:

2013

Langue:

english

Fichier:

PDF, 900 KB

english, 2013

13

Protein-Ligand Interaction Study of Cp OGA in Complex with GlcNAcstatin

Sousa, Paulo Robson M., de Alencar, Nelson Alberto N., Lima, Anderson H., Lameira, Jerônimo, Alves, Cláudio Nahum

Journal:

Chemical Biology & Drug Design

Année:

2013

Langue:

english

Fichier:

PDF, 575 KB

english, 2013

14

Investigating Mammalian Tyrosine Phosphatase Inhibitors as Potential ‘Piggyback’ Leads to Target Trypanosoma brucei Transmission

Ruberto, Irene, Szoor, Balazs, Clark, Rachel, Matthews, Keith R.

Journal:

Chemical Biology & Drug Design

Année:

2013

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2013

15

Alanine Scan of an Immunosuppressive Peptide (CP): Analysis of Structure-Function Relationships

Raguine, Laura, Ali, Marina, Bender, Veronika, Diefenbach, Eve, Doddareddy, Munikumar Reddy, Hibbs, David, Manolios, Nicholas

Journal:

Chemical Biology & Drug Design

Année:

2013

Langue:

english

Fichier:

PDF, 712 KB

english, 2013

16

Identification of Novel Anaplastic Lymphoma Kinase (ALK) Inhibitors Using a Common Feature Pharmacophore Model Derived from Known Ligands Crystallized with ALK

Xie, Huan-Zhang, Lan, Hai, Pan, You-Li, Zou, Jun, Wang, Ze-Rong, Li, Lin-Li, Huang, Qi, Zhang, Hui, Yang, Sheng-Yong

Journal:

Chemical Biology & Drug Design

Année:

2013

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2013