Volume 80; Issue 6

Chemical Biology & Drug Design

Volume 80; Issue 6

1

Computational Studies of Novel Chymase Inhibitors Against Cardiovascular and Allergic Diseases: Mechanism and Inhibition

Arooj, Mahreen, Thangapandian, Sundarapandian, John, Shalini, Hwang, Swan, Park, Jong K., Lee, Keun W.

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 902 KB

english, 2012

2

Synthesis, Evaluation and Molecular Docking of Thiazolopyrimidine Derivatives as Dipeptidyl Peptidase IV Inhibitors

Sharma, Mani, Gupta, Monica, Singh, Divya, Kumar, Manoj, Kaur, Punit

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2012

3

Pharmacophore-Based Virtual Screening to Aid in the Identification of Unknown Protein Function

Mallipeddi, Prema L., Joshi, Manali, Briggs, James M.

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 450 KB

english, 2012

4

Evaluation of Structurally Diverse Benzoazepines Clubbed with Coumarins as Mycobacterium tuberculosis Agents

Upadhyay, Kuldip, Manvar, Atul, Rawal, Kena, Joshi, Sudhir, Trivedi, Jalpa, Chaniyara, Ravi, Shah, Anamik

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 221 KB

english, 2012

5

Discovering Novel α-aminoacyl-Containing Proline Derivatives with Potent and Selective Inhibitory Activity Against Dipeptidyl Peptidase IV: Design, Synthesis, Biological Evaluation, and Molecular Modeling

Zhang, Xiaodong, Wang, Jiang, Su, Mingbo, Li, Zeng, Li, Jingya, Li, Jia, Liu, Hong

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 306 KB

english, 2012

6

Syntheses and In Vitro Anticancer Properties of Novel Radiosensitizers

Ates-Alagoz, Zeynep, Coleman, Natalia, Martin, Marlena, Wan, Aaron, Adejare, Adeboye

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 643 KB

english, 2012

7

Evaluation of Imidazole-Based Compounds as Heme Oxygenase-1 Inhibitors

Sorrenti, Valeria, Guccione, Salvatore, Di Giacomo, Claudia, Modica, Maria N., Pittalà, Valeria, Acquaviva, Rosaria, Basile, Livia, Pappalardo, Morena, Salerno, Loredana

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 538 KB

english, 2012

8

Bioactive Derivatives of Curcumin Attenuate Cataract Formation In Vitro

Radha, Asha, Devi Rukhmini, Sudha, Vilasini, Sasikala, Rajan Sakunthala, Priya, Sreedharan, Balachandran, Puzhavoorparambil Velayudhan, Mohanan, Abraham, Annie

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 120 KB

english, 2012

9

Discovery of Novel Vascular Endothelial Growth Factor Receptor 2 Inhibitors: A Virtual Screening Approach

Zhang, Lei, Wang, Xuejian, Feng, Jinhong, Jia, Yuping, Xu, Fuming, Xu, Wenfang

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2012

10

In Silico Modeling of the Molecular Structure and Binding of Leukotriene A4 into Leukotriene A4 Hydrolase

Paz, Paula B., Vega-Hissi, Esteban G., Estrada, Mario R., Garro Martinez, Juan C.

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 308 KB

english, 2012

11

Synthesis, Cytotoxicity, and Cell Death Profile of Polyaminoanthraquinones as Antitumor Agents

Wang, Jianhong, Gao, Ruihong, Li, Qian, Xie, Songqiang, Zhao, Jin, Wang, Chaojie

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 486 KB

english, 2012

12

Discovery of Potent, Novel Nrf2 Inducers Via Quantum Modeling, Virtual Screening, and In Vitro Experimental Validation

Williamson, Tracy P., Amirahmadi, Sara, Joshi, Gururaj, Kaludov, Nikola K., Martinov, Martin N., Johnson, Delinda A., Johnson, Jeffrey A.

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 898 KB

english, 2012

13

Biological Effects of AL622, a Molecule Rationally Designed to Release an EGFR and a c-Src Kinase Inhibitor

Larroque-Lombard, Anne-Laure, Ning, Na, Rao, Suman, Lauwagie, Sylvia, Halaoui, Ruba, Coudray, Laëtitia, Huang, Ying, Jean-Claude, Bertrand J.

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 802 KB

english, 2012

14

Synthesis and Biological Evaluation of Coumarin Derivatives as Inhibitors of Mycobacterium bovis (BCG)

Rezayan, Ali Hossein, Azerang, Parisa, Sardari, Soroush, Sarvary, Afshin

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 123 KB

english, 2012

15

Probing Secondary Glutaminyl Cyclase (QC) Inhibitor Interactions Applying an in silico-Modeling/Site-Directed Mutagenesis Approach: Implications for Drug Development

Koch, Birgit, Buchholz, Mirko, Wermann, Michael, Heiser, Ulrich, Schilling, Stephan, Demuth, Hans-Ulrich

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 469 KB

english, 2012

16

Synthesis and Anti-HIV Properties of New Carbamate Prodrugs of AZT

Solyev, Pavel N., Shipitsin, Alexander V., Karpenko, Inna L., Nosik, Dmitry N., Kalnina, Ludmila B., Kochetkov, Sergey N., Kukhanova, Marina K., Jasko, Maxim V.

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 121 KB

english, 2012

17

Potent Melanin Production Enhancement of Human Tyrosinase Gene by Tat and an Entrapment in Elastic Cationic Niosomes: Potential Application in Vitiligo Gene Therapy

Manosroi, Jiradej, Khositsuntiwong, Narinthorn, Götz, Friedrich, Werner, Rolf G., Manosroi, Worapaka, Manosroi, Aranya

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 257 KB

english, 2012

18

Discovery of Novel 1,2,4-Triazol-5-Ones as Tumor Necrosis Factor-Alpha Inhibitors for the Treatment of Neuropathic Pain

Sharma, Monika, Garigipati, Sowmya, Kundu, Binita, Vanamala, Deekshith, Semwal, Arvind, Sriram, Dharmarajan, Yogeeswari, Perumal

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 233 KB

english, 2012

19

Conformational Adaptation Drives Potent, Selective and Durable Inhibition of the Human Protein Methyltransferase DOT1L

Basavapathruni, Aravind, Jin, Lei, Daigle, Scott R., Majer, Christina R. A., Therkelsen, Carly A., Wigle, Tim J., Kuntz, Kevin W., Chesworth, Richard, Pollock, Roy M., Scott, Margaret P., Moyer, Mikel

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 373 KB

english, 2012

20

siRNA Delivery: From Lipids to Cell-penetrating Peptides and Their Mimics

Gooding, Matt, Browne, Lorcan P., Quinteiro, Filipa M., Selwood, David L.

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 533 KB

english, 2012

21

Study of Chemical Ligation Via 17-, 18- and 19-Membered Cyclic Transition States

Panda, Siva S., El-Nachef, Claudia, Bajaj, Kiran, Al-Youbi, Abdulrahman O., Oliferenko, Alexander, Katritzky, Alan R.

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 178 KB

english, 2012

22

Chemotherapy Drugs Form Ion Pores in Membranes Due to Physical Interactions with Lipids

Ashrafuzzaman, Mohammad, Tseng, Chih-Yuan, Duszyk, Marek, Tuszynski, Jack A.

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 651 KB

english, 2012

23

Issue Information

Journal:

Chemical Biology & Drug Design

Année:

2012

Langue:

english

Fichier:

PDF, 282 KB

english, 2012