Volume 78; Issue 3

Chemical Biology & Drug Design

Volume 78; Issue 3

1

Molecular Modeling Studies on Benzimidazole Carboxamide Derivatives as PARP-1 Inhibitors Using 3D-QSAR and Docking

Huahui Zeng, Huabei Zhang, Fubin Jang, Lingzhou Zhao, Jianyuan Zhang

Journal:

Chemical Biology & Drug Design

Année:

2011

Langue:

english

Fichier:

PDF, 892 KB

english, 2011

2

Designing and Engineering of a Site-specific Incorporation of a Keto Group in Uricase

Zhengzhi Fang, Yaguang Liu, Jingxian Liu, Renhua Sun, Hai Chen, Xiangdong Gao, Wenbing Yao

Journal:

Chemical Biology & Drug Design

Année:

2011

Langue:

english

Fichier:

PDF, 353 KB

english, 2011

3

Role of Interactions and Volume Variation in Discriminating Active and Inactive Forms of Cyclin-Dependent Kinase-2 Inhibitor Complexes

Nallusamy Saranya, Samuel Selvaraj

Journal:

Chemical Biology & Drug Design

Année:

2011

Langue:

english

Fichier:

PDF, 212 KB

english, 2011

4

Design, Synthesis, and Evaluation of Thiazolidinone Derivatives as Antimicrobial and Anti-viral Agents

Veerasamy Ravichandran, Abhishek Jain, Krishnan S. Kumar, Harish Rajak, Ram K. Agrawal

Journal:

Chemical Biology & Drug Design

Année:

2011

Langue:

english

Fichier:

PDF, 141 KB

english, 2011

5

Knowledge-Based Identification of the ERK2/STAT3 Signal Pathway as a Therapeutic Target for Type 2 Diabetes and Drug Discovery

Takayoshi Kinoshita, Kentaro Doi, Hajime Sugiyama, Shuhei Kinoshita, Mutsuyo Wada, Shuji Naruto, Atsushi Tomonaga

Journal:

Chemical Biology & Drug Design

Année:

2011

Langue:

english

Fichier:

PDF, 425 KB

english, 2011

6

Anti-Stroke Profile of Thiazolidin-4-One Derivatives in Focal Cerebral Ischemia Model in Rat

Ram Raghubir, Rajkumar Verma, Sheeba S. Samuel, Saman Raza, Wajahul Haq, Seturam B. Katti

Journal:

Chemical Biology & Drug Design

Année:

2011

Langue:

english

Fichier:

PDF, 338 KB

english, 2011

7

Synthesis and Evaluation of Antimalarial Activity of Oxygenated 3-alkylpyridine Marine Alkaloid Analogues

Flaviane F. Hilário, Renata Cristina de Paula, Mariana L. T. Silveira, Gustavo H. R. Viana, Rosemeire B. Alves, Juliana R. C. S. Pereira, Luciana Maria Silva, Rossimiriam P. de Freitas, Fernando de Pi

Journal:

Chemical Biology & Drug Design

Année:

2011

Langue:

english

Fichier:

PDF, 274 KB

english, 2011

8

Study of Human Dopamine Sulfotransferases Based on Gene Expression Programming

Hongzong Si, Jiangang Zhao, Lianhua Cui, Ning Lian, Hanlin Feng, Yun-Bo Duan, Zhide Hu

Journal:

Chemical Biology & Drug Design

Année:

2011

Langue:

english

Fichier:

PDF, 415 KB

english, 2011

9

High-Throughput Analysis of an RNAi Library Identifies Novel Kinase Targets in Trypanosoma brucei

Zachary B. Mackey, Kyriacos Koupparis, Mari Nishino, James H. McKerrow

Journal:

Chemical Biology & Drug Design

Année:

2011

Langue:

english

Fichier:

PDF, 895 KB

english, 2011

10

CoMFA, CoMSIA, and Docking Studies on Thiolactone-Class of Potent Anti-malarials: Identification of Essential Structural Features Modulating Anti-malarial Activity

Kuldeep K. Roy, Shome S. Bhunia, Anil K. Saxena

Journal:

Chemical Biology & Drug Design

Année:

2011

Langue:

english

Fichier:

PDF, 600 KB

english, 2011

11

Structure-Based Virtual Screening of Glycogen Synthase Kinase 3β Inhibitors: Analysis of Scoring Functions Applied to Large True Actives and Decoy Sets

Dmitry I. Osolodkin, Vladimir A. Palyulin, Nikolay S. Zefirov

Journal:

Chemical Biology & Drug Design

Année:

2011

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2011

12

Discovery of New Antifungal Leads via Pharmacophore Modeling and QSAR Analysis of Fungal N-Myristoyl Transferase Inhibitors Followed by In Silico Screening

Mutasem O. Taha, Amjad M. Qandil, Tariq Al-Haraznah, Reema Abu Khalaf, Hiba Zalloum, Amal G. Al-Bakri

Journal:

Chemical Biology & Drug Design

Année:

2011

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2011

13

Pharmacophore Modeling and Density Functional Theory Analysis for A Series of Nitroimidazole Compounds with Antitubercular Activity

Nilesh R. Tawari, Mariam S. Degani

Journal:

Chemical Biology & Drug Design

Année:

2011

Langue:

english

Fichier:

PDF, 909 KB

english, 2011

14

3D-QSAR and Docking Studies on the HEPT Derivatives of HIV-1 Reverse Transcriptase

Ramaswamy Sree Latha, Ramadoss Vijayaraj, Ettayapuram Ramaprasad Azhagiya Singam, Krishnaswamy Chitra, Venkatesan Subramanian

Journal:

Chemical Biology & Drug Design

Année:

2011

Langue:

english

Fichier:

PDF, 373 KB

english, 2011

15

Revealing the Drug-Resistant Mechanism for Diarylpyrimidine Analogue Inhibitors of HIV-1 Reverse Transcriptase

Hao Zhang, Fang Qin, Wei Ye, Zeng Li, Songyao Ma, Yan Xia, Yi Jiang, Jiayi Zhu, Yixue Li, Jian Zhang, Hai-Feng Chen

Journal:

Chemical Biology & Drug Design

Année:

2011

Langue:

english

Fichier:

PDF, 315 KB

english, 2011

16

Non-Bisphosphonate Inhibitors of Isoprenoid Biosynthesis Identified via Computer-Aided Drug Design

Jacob D. Durrant, Rong Cao, Alemayehu A. Gorfe, Wei Zhu, Jikun Li, Anna Sankovsky, Eric Oldfield, J. Andrew McCammon

Journal:

Chemical Biology & Drug Design

Année:

2011

Langue:

english

Fichier:

PDF, 452 KB

english, 2011

17

Safety and Efficacy of New 3,6-diaryl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine Analogs as Potential Phosphodiesterase-4 Inhibitors in NIH-3T3 Mouse Fibroblastic Cells

Maryam Baeeri, Alireza Foroumadi, Maryam Motamedi, Azadeh Yahya-Meymandi, Loghman Firoozpour, Seyed N. Ostad, Abbas Shafiee, Saeid Souzangarzadeh, Mohammad Abdollahi

Journal:

Chemical Biology & Drug Design

Année:

2011

Langue:

english

Fichier:

PDF, 249 KB

english, 2011

18

Issue Information

Journal:

Chemical Biology & Drug Design

Année:

2011

Langue:

english

Fichier:

PDF, 978 KB

english, 2011