Volume 73; Issue 1

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Cancer Research
Volume 73; Issue 1

Cancer Research

Volume 73; Issue 1

1

Single-Molecule Genomic Data Delineate Patient-Specific Tumor Profiles and Cancer Stem Cell Organization

Sottoriva, A., Spiteri, I., Shibata, D., Curtis, C., Tavare, S.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 802 KB

english, 2013

2

Cisplatin Selects for Multidrug-Resistant CD133+ Cells in Lung Adenocarcinoma by Activating Notch Signaling

Liu, Y.-P., Yang, C.-J., Huang, M.-S., Yeh, C.-T., Wu, A. T. H., Lee, Y.-C., Lai, T.-C., Lee, C.-H., Hsiao, Y.-W., Lu, J., Shen, C.-N., Lu, P.-J., Hsiao, M.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2013

3

Dose-Dense Chemotherapy Improves Mechanisms of Antitumor Immune Response

Chang, C.-L., Hsu, Y.-T., Wu, C.-C., Lai, Y.-Z., Wang, C., Yang, Y.-C., Wu, T.- C., Hung, C.-F.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 808 KB

english, 2013

4

STAT5 Is Crucial to Maintain Leukemic Stem Cells in Acute Myelogenous Leukemias Induced by MOZ-TIF2

Tam, W. F., Hahnel, P. S., Schuler, A., Lee, B. H., Okabe, R., Zhu, N., Pante, S. V., Raffel, G., Mercher, T., Wernig, G., Bockamp, E., Sasca, D., Kreft, A., Robinson, G. W., Hennighausen, L., Gillila

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 645 KB

english, 2013

5

Antitumor Immunotherapeutic and Toxic Properties of an HDL-Conjugated Chimeric IL-15 Fusion Protein

Ochoa, M. C., Fioravanti, J., Rodriguez, I., Hervas-Stubbs, S., Azpilikueta, A., Mazzolini, G., Gurpide, A., Prieto, J., Pardo, J., Berraondo, P., Melero, I.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2013

6

Autophagy Control by the VEGF-C/NRP-2 Axis in Cancer and Its Implication for Treatment Resistance

Stanton, M. J., Dutta, S., Zhang, H., Polavaram, N. S., Leontovich, A. A., Honscheid, P., Sinicrope, F. A., Tindall, D. J., Muders, M. H., Datta, K.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.78 MB

english, 2013

7

PD-1-Expressing Tumor-Infiltrating T Cells Are a Favorable Prognostic Biomarker in HPV-Associated Head and Neck Cancer

Badoual, C., Hans, S., Merillon, N., Van Ryswick, C., Ravel, P., Benhamouda, N., Levionnois, E., Nizard, M., Si-Mohamed, A., Besnier, N., Gey, A., Rotem-Yehudar, R., Pere, H., Tran, T., Guerin, C. L.,

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2013

8

Immune-Dependent and Independent Antitumor Activity of GM-CSF Aberrantly Expressed by Mouse and Human Colorectal Tumors

Urdinguio, R. G., Fernandez, A. F., Moncada-Pazos, A., Huidobro, C., Rodriguez, R. M., Ferrero, C., Martinez-Camblor, P., Obaya, A. J., Bernal, T., Parra-Blanco, A., Rodrigo, L., Santacana, M., Matias

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 790 KB

english, 2013

9

S100A9 Is a Novel Ligand of EMMPRIN That Promotes Melanoma Metastasis

Hibino, T., Sakaguchi, M., Miyamoto, S., Yamamoto, M., Motoyama, A., Hosoi, J., Shimokata, T., Ito, T., Tsuboi, R., Huh, N.-h.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2013

10

Targeting CD4+ T-Helper Cells Improves the Induction of Antitumor Responses in Dendritic Cell-Based Vaccination

Aarntzen, E. H. J. G., De Vries, I. J. M., Lesterhuis, W. J., Schuurhuis, D., Jacobs, J. F. M., Bol, K., Schreibelt, G., Mus, R., De Wilt, J. H. W., Haanen, J. B. A. G., Schadendorf, D., Croockewit, A

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 739 KB

english, 2013

11

Angiopoietin-2 Functions as a Tie2 Agonist in Tumor Models, Where It Limits the Effects of VEGF Inhibition

Daly, C., Eichten, A., Castanaro, C., Pasnikowski, E., Adler, A., Lalani, A. S., Papadopoulos, N., Kyle, A. H., Minchinton, A. I., Yancopoulos, G. D., Thurston, G.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 610 KB

english, 2013

12

Spatiotemporal Assessments of Dermal Hyperemia Enable Accurate Prediction of Experimental Cutaneous Carcinogenesis as well as Chemopreventive Activity

Konger, R. L., Xu, Z., Sahu, R. P., Rashid, B. M., Mehta, S. R., Mohamed, D. R., DaSilva-Arnold, S. C., Bradish, J. R., Warren, S. J., Kim, Y. L.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2013

13

Genomic Profiling of Isolated Circulating Tumor Cells from Metastatic Breast Cancer Patients

Magbanua, M. J. M., Sosa, E. V., Roy, R., Eisenbud, L. E., Scott, J. H., Olshen, A., Pinkel, D., Rugo, H. S., Park, J. W.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 2.05 MB

english, 2013

14

Chloroquine in Cancer Therapy: A Double-Edged Sword of Autophagy

Kimura, T., Takabatake, Y., Takahashi, A., Isaka, Y.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 464 KB

english, 2013

15

PIK3CA Mutation H1047R Is Associated with Response to PI3K/AKT/mTOR Signaling Pathway Inhibitors in Early-Phase Clinical Trials

Janku, F., Wheler, J. J., Naing, A., Falchook, G. S., Hong, D. S., Stepanek, V. M., Fu, S., Piha-Paul, S. A., Lee, J. J., Luthra, R., Tsimberidou, A. M., Kurzrock, R.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 494 KB

english, 2013

16

Biologic Challenges in the Detection of Circulating Tumor Cells

Joosse, S. A., Pantel, K.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 466 KB

english, 2013

17

A Preclinical Mouse Model of Invasive Lobular Breast Cancer Metastasis

Doornebal, C. W., Klarenbeek, S., Braumuller, T. M., Klijn, C. N., Ciampricotti, M., Hau, C.-S., Hollmann, M. W., Jonkers, J., de Visser, K. E.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.46 MB

english, 2013

18

NF- B Activity Regulates Mesenchymal Stem Cell Accumulation at Tumor Sites

Uchibori, R., Tsukahara, T., Mizuguchi, H., Saga, Y., Urabe, M., Mizukami, H., Kume, A., Ozawa, K.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 881 KB

english, 2013

19

ABL Regulation by AXL Promotes Cisplatin Resistance in Esophageal Cancer

Hong, J., Peng, D., Chen, Z., Sehdev, V., Belkhiri, A.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.63 MB

english, 2013

20

A Classification Model for BRCA2 DNA Binding Domain Missense Variants Based on Homology-Directed Repair Activity

Guidugli, L., Pankratz, V. S., Singh, N., Thompson, J., Erding, C. A., Engel, C., Schmutzler, R., Domchek, S., Nathanson, K., Radice, P., Singer, C., Tonin, P. N., Lindor, N. M., Goldgar, D. E., Couch

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 899 KB

english, 2013

21

Characterization of Rearrangements Involving the ALK Gene Reveals a Novel Truncated Form Associated with Tumor Aggressiveness in Neuroblastoma

Cazes, A., Louis-Brennetot, C., Mazot, P., Dingli, F., Lombard, B., Boeva, V., Daveau, R., Cappo, J., Combaret, V., Schleiermacher, G., Jouannet, S., Ferrand, S., Pierron, G., Barillot, E., Loew, D.,

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.82 MB

english, 2013

22

MicroRNAs Regulate Tumor Angiogenesis Modulated by Endothelial Progenitor Cells

Plummer, P. N., Freeman, R., Taft, R. J., Vider, J., Sax, M., Umer, B. A., Gao, D., Johns, C., Mattick, J. S., Wilton, S. D., Ferro, V., McMillan, N. A. J., Swarbrick, A., Mittal, V., Mellick, A. S.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.86 MB

english, 2013

23

EGFR/JIP-4/JNK2 Signaling Attenuates Cetuximab-Mediated Radiosensitization of Squamous Cell Carcinoma Cells

Eke, I., Schneider, L., Forster, C., Zips, D., Kunz-Schughart, L. A., Cordes, N.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 990 KB

english, 2013

24

Novel DNA Damage Checkpoints Mediating Cell Death Induced by the NEDD8-Activating Enzyme Inhibitor MLN4924

Blank, J. L., Liu, X. J., Cosmopoulos, K., Bouck, D. C., Garcia, K., Bernard, H., Tayber, O., Hather, G., Liu, R., Narayanan, U., Milhollen, M. A., Lightcap, E. S.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2013

25

-Catulin Drives Metastasis by Activating ILK and Driving an v 3 Integrin Signaling Axis

Liang, C.-H., Chiu, S.-Y., Hsu, I.-L., Wu, Y.-Y., Tsai, Y.-T., Ke, J.-Y., Pan, S.-H., Hsu, Y.-C., Li, K.-C., Yang, P.-C., Chen, Y.-L., Hong, T.-M.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 2.59 MB

english, 2013

26

PNUTS Functions as a Proto-Oncogene by Sequestering PTEN

Kavela, S., Shinde, S. R., Ratheesh, R., Viswakalyan, K., Bashyam, M. D., Gowrishankar, S., Vamsy, M., Pattnaik, S., Rao, S., Sastry, R. A., Srinivasulu, M., Chen, J., Maddika, S.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2013

27

Preventing Postoperative Metastatic Disease by Inhibiting Surgery-Induced Dysfunction in Natural Killer Cells

Tai, L.-H., de Souza, C. T., Belanger, S., Ly, L., Alkayyal, A. A., Zhang, J., Rintoul, J. L., Ananth, A. A., Lam, T., Breitbach, C. J., Falls, T. J., Kirn, D. H., Bell, J. C., Makrigiannis, A. P., Au

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.56 MB

english, 2013

28

Production of Gastrointestinal Tumors in Mice by Modulating Latent TGF- 1 Activation

Shibahara, K., Ota, M., Horiguchi, M., Yoshinaga, K., Melamed, J., Rifkin, D. B.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2013

29

Constitutive HER2 Signaling Promotes Breast Cancer Metastasis through Cellular Senescence

Angelini, P. D., Fluck, M. F. Z., Pedersen, K., Parra-Palau, J. L., Guiu, M., Bernado Morales, C., Vicario, R., Luque-Garcia, A., Navalpotro, N. P., Giralt, J., Canals, F., Gomis, R. R., Tabernero, J.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2013

30

Inhibiting Interactions of Lysine Demethylase LSD1 with Snail/Slug Blocks Cancer Cell Invasion

Ferrari-Amorotti, G., Fragliasso, V., Esteki, R., Prudente, Z., Soliera, A. R., Cattelani, S., Manzotti, G., Grisendi, G., Dominici, M., Pieraccioli, M., Raschella, G., Chiodoni, C., Colombo, M. P., C

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 2.94 MB

english, 2013

31

A Tumorigenic MLL-Homeobox Network in Human Glioblastoma Stem Cells

Gallo, M., Ho, J., Coutinho, F. J., Vanner, R., Lee, L., Head, R., Ling, E. K. M., Clarke, I. D., Dirks, P. B.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.79 MB

english, 2013

32

Critical Role for the Receptor Tyrosine Kinase EPHB4 in Esophageal Cancers

Hasina, R., Mollberg, N., Kawada, I., Mutreja, K., Kanade, G., Yala, S., Surati, M., Liu, R., Li, X., Zhou, Y., Ferguson, B. D., Nallasura, V., Cohen, K. S., Hyjek, E., Mueller, J., Kanteti, R., El Ha

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 3.45 MB

english, 2013

33

Correction: Cyclin D2-Cyclin-Dependent Kinase 4/6 Is Required for Efficient Proliferation and Tumorigenesis following Apc Loss

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 347 KB

english, 2013

34

Vaccination with Antigen-Transfected, NKT Cell Ligand-Loaded, Human Cells Elicits Robust In Situ Immune Responses by Dendritic Cells

Shimizu, K., Mizuno, T., Shinga, J., Asakura, M., Kakimi, K., Ishii, Y., Masuda, K., Maeda, T., Sugahara, H., Sato, Y., Matsushita, H., Nishida, K., Hanada, K., Dorrie, J., Schaft, N., Bickham, K., Ko

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.71 MB

english, 2013

35

Augmenting Antitumor T-Cell Responses to Mimotope Vaccination by Boosting with Native Tumor Antigens

Buhrman, J. D., Jordan, K. R., U'Ren, L., Sprague, J., Kemmler, C. B., Slansky, J. E.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2013

36

mTOR Inhibitor RAD001 Promotes Metastasis in a Rat Model of Pancreatic Neuroendocrine Cancer

Pool, S. E., Bison, S., Koelewijn, S. J., van der Graaf, L. M., Melis, M., Krenning, E. P., de Jong, M.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2013

37

Targeting Truncated Retinoid X Receptor- by CF31 Induces TNF- -Dependent Apoptosis

Wang, G.-H., Jiang, F.-Q., Duan, Y.-H., Zeng, Z.-P., Chen, F., Dai, Y., Chen, J.-B., Liu, J.-X., Liu, J., Zhou, H., Chen, H.-F., Zeng, J.-Z., Su, Y., Yao, X.-S., Zhang, X.-K.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2013

38

E3 Ubiquitin Ligase RNF126 Promotes Cancer Cell Proliferation by Targeting the Tumor Suppressor p21 for Ubiquitin-Mediated Degradation

Zhi, X., Zhao, D., Wang, Z., Zhou, Z., Wang, C., Chen, W., Liu, R., Chen, C.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 2.72 MB

english, 2013

39

RhoB Differentially Controls Akt Function in Tumor Cells and Stromal Endothelial Cells during Breast Tumorigenesis

Kazerounian, S., Gerald, D., Huang, M., Chin, Y. R., Udayakumar, D., Zheng, N., O'Donnell, R. K., Perruzzi, C., Mangiante, L., Pourat, J., Phung, T. L., Bravo-Nuevo, A., Shechter, S., McNamara, S., Du

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 2.56 MB

english, 2013

40

Superior Penetration and Retention Behavior of 50 nm Gold Nanoparticles in Tumors

Huo, S., Ma, H., Huang, K., Liu, J., Wei, T., Jin, S., Zhang, J., He, S., Liang, X.-J.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 3.17 MB

english, 2013

41

Genome-Wide Association Study Reveals Novel Genetic Determinants of DNA Repair Capacity in Lung Cancer

Wang, L.-E., Gorlova, O. Y., Ying, J., Qiao, Y., Weng, S.-F., Lee, A. T., Gregersen, P. K., Spitz, M. R., Amos, C. I., Wei, Q.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 261 KB

english, 2013

42

Kinase Pathway Dependence in Primary Human Leukemias Determined by Rapid Inhibitor Screening

Tyner, J. W., Yang, W. F., Bankhead, A., Fan, G., Fletcher, L. B., Bryant, J., Glover, J. M., Chang, B. H., Spurgeon, S. E., Fleming, W. H., Kovacsovics, T., Gotlib, J. R., Oh, S. T., Deininger, M. W.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 2.20 MB

english, 2013

43

MIG-7 Controls COX-2/PGE2-Mediated Lung Cancer Metastasis

Ho, M.-Y., Liang, S.-M., Hung, S.-W., Liang, C.-M.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 2.98 MB

english, 2013

44

SpliceArray Profiling of Breast Cancer Reveals a Novel Variant of NCOR2/SMRT That Is Associated with Tamoxifen Resistance and Control of ER Transcriptional Activity

Zhang, L., Gong, C., Lau, S. L. Y., Yang, N., Wong, O. G. W., Cheung, A. N. Y., Tsang, J. W. H., Chan, K. Y. K., Khoo, U.-S.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 744 KB

english, 2013

45

p38 Inhibits Liver Fibrogenesis and Consequent Hepatocarcinogenesis by Curtailing Accumulation of Reactive Oxygen Species

Sakurai, T., Kudo, M., Umemura, A., He, G., Elsharkawy, A. M., Seki, E., Karin, M.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2013

46

A Unique Galectin Signature in Human Prostate Cancer Progression Suggests Galectin-1 as a Key Target for Treatment of Advanced Disease

Laderach, D. J., Gentilini, L. D., Giribaldi, L., Delgado, V. C., Nugnes, L., Croci, D. O., Al Nakouzi, N., Sacca, P., Casas, G., Mazza, O., Shipp, M. A., Vazquez, E., Chauchereau, A., Kutok, J. L., R

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2013