Volume 3; Issue 1

Journal for ImmunoTherapy of Cancer

Volume 3; Issue 1

1

Combined immune checkpoint protein blockade and low dose whole body irradiation as immunotherapy for myeloma

Jing, Weiqing, Gershan, Jill A, Weber, James, Tlomak, Dominique, McOlash, Laura, Sabatos-Peyton, Catherine, Johnson, Bryon D

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2015

2

Early transduction produces highly functional chimeric antigen receptor-modified virus-specific T-cells with central memory markers: a Production Assistant for Cell Therapy (PACT) translational application

Sun, Jiali, Huye, Leslie E, Lapteva, Natalia, Mamonkin, Maksim, Hiregange, Manasa, Ballard, Brandon, Dakhova, Olga, Raghavan, Darshana, Durett, April G, Perna, Serena K, Omer, Bilal, Rollins, Lisa A,

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 3.02 MB

english, 2015

3

T cell-NF-κB activation is required for tumor controlin vivo

Barnes, Sarah E, Wang, Ying, Chen, Luqiu, Molinero, Luciana L, Gajewski, Thomas F, Evaristo, Cesar, Alegre, Maria-Luisa

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2015

4

Apical ballooning and cardiomyopathy in a melanoma patient treated with ipilimumab: a case of takotsubo-like syndrome

Geisler, Benjamin P, Raad, Roy A, Esaian, Diana, Sharon, Elad, Schwartz, David R

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 3.31 MB

english, 2015

5

Combination of IFNα and poly-I:C reprograms bladder cancer microenvironment for enhanced CTL attraction

Muthuswamy, Ravikumar, Wang, Liwen, Pitteroff, Jamie, Gingrich, Jeffrey R, Kalinski, Pawel

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 904 KB

english, 2015

6

Immunotherapeutic approaches to ovarian cancer treatment

Chester, Cariad, Dorigo, Oliver, Berek, Jonathan S, Kohrt, Holbrook

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 443 KB

english, 2015

7

Preamble to the 2015 SITC immunotherapy biomarkers taskforce

Butterfield, Lisa H, Disis, Mary L, Fox, Bernard A, Khleif, Samir N, Marincola, Francesco M

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 307 KB

english, 2015

8

New perspective on targeting the tumor suppressor p53 pathway in the tumor microenvironment to enhance the efficacy of immunotherapy

Guo, Gang, Cui, Yan

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 883 KB

english, 2015

9

Immune therapy of metastatic melanoma developing after allogeneic bone marrow transplant

Cecchini, Michael, Sznol, Mario, Seropian, Stuart

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 334 KB

english, 2015

10

Survival with AGS-003, an autologous dendritic cell–based immunotherapy, in combination with sunitinib in unfavorable risk patients with advanced renal cell carcinoma (RCC): Phase 2 study results

Amin, Asim, Dudek, Arkadiusz Z, Logan, Theodore F, Lance, Raymond S, Holzbeierlein, Jeffrey M, Knox, Jennifer J, Master, Viraj A, Pal, Sumanta K, Miller, Wilson H, Karsh, Lawrence I, Tcherepanova, Iri

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 1.94 MB

english, 2015

11

The therapeutic promise of disrupting the PD-1/PD-L1 immune checkpoint in cancer: unleashing the CD8 T cell mediated anti-tumor activity results in significant, unprecedented clinical efficacy in various solid tumors

Romano, Emanuela, Romero, Pedro

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 2.29 MB

english, 2015

12

Human tumor infiltrating lymphocytes cooperatively regulate prostate tumor growth in a humanized mouse model

Roth, Michael D, Harui, Airi

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 1.46 MB

english, 2015

13

Acute heart failure due to autoimmune myocarditis under pembrolizumab treatment for metastatic melanoma

Läubli, Heinz, Balmelli, Cathrin, Bossard, Matthias, Pfister, Otmar, Glatz, Kathrin, Zippelius, Alfred

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 2.41 MB

english, 2015

14

Programmed death ligand-1 expression in adrenocortical carcinoma: an exploratory biomarker study

Fay, André P, Signoretti, Sabina, Callea, Marcella, Telό, Gabriela H, McKay, Rana R, Song, Jiaxi, Carvo, Ingrid, Lampron, Megan E, Kaymakcalan, Marina D, Poli-de-Figueiredo, Carlos E, Bellmunt, Joaqui

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2015

15

29thAnnual meeting of the Society for Immunotherapy of Cancer (SITC)

Hurwitz, Arthur A, Lee, Sylvia, Knox, Susan, Kohrt, Holbrook, Verdeil, Gregory, Romano, Emanuela, Margolin, Kim, Urba, Walter J, Speiser, Daniel E

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 734 KB

english, 2015

16

Bridging infectious disease vaccines with cancer immunotherapy: a role for targeted RNA based immunotherapeutics

Sayour, Elias J, Sanchez-Perez, Luis, Flores, Catherine, Mitchell, Duane A

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 417 KB

english, 2015

17

Pembrolizumab

Khoja, Leila, Butler, Marcus O., Kang, S. Peter, Ebbinghaus, Scot, Joshua, Anthony M.

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 582 KB

english, 2015

18

Target discovery for T cell therapy: next steps to advance Immunotherapies

Bot, Adrian, Brewer, Joanna E, Eshhar, Zelig, Frankel, Stanley R, Hickman, Emma, Jungbluth, Achim A, Morgan, Richard, Peretz, Yoav, Radvanyi, Laszlo, Ramos, Carlos A, Robbins, Paul F, Wucherpfennig, K

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 722 KB

english, 2015

19

Immune monitoring technology primer: immunosequencing

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 394 KB

english, 2015

20

Quantitative real-time PCR assisted cell counting (qPACC) for epigenetic - based immune cell quantification in blood and tissue

Kleen, Thomas Oliver, Yuan, Jianda

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 871 KB

english, 2015

21

Tasquinimod triggers an early change in the polarization of tumor associated macrophages in the tumor microenvironment

Olsson, Anders, Nakhlé, Jessica, Sundstedt, Anette, Plas, Pascale, Bauchet, Anne-Laure, Pierron, Valérie, Bruetschy, Luce, Deronic, Adnan, Törngren, Marie, Liberg, David, Schmidlin, Fabien, Leanderson

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2015

22

Tumor immunology and cancer immunotherapy: summary of the 2014 SITC primer

Page, David B., Bourla, Ariel Bulua, Daniyan, Anthony, Naidoo, Jarushka, Smith, Eric, Smith, Melody, Friedman, Claire, Khalil, Danny N., Funt, Samuel, Shoushtari, Alexander N., Overwijk, Willem W., Sh

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 467 KB

english, 2015

23

Designed ankyrin repeat proteins are effective targeting elements for chimeric antigen receptors

Hammill, Joanne A., VanSeggelen, Heather, Helsen, Christopher W., Denisova, Galina F., Evelegh, Carole, Tantalo, Daniela G. M., Bassett, Jennifer D., Bramson, Jonathan L.

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 1.51 MB

english, 2015

24

Mismatch repair deficiency associated with complete remission to combination programmed cell death ligand immune therapy in a patient with sporadic urothelial carcinoma: immunotheranostic considerations

Castro, Michael P., Goldstein, Neal

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 2.26 MB

english, 2015

25

Combination immunotherapy: Where do we go from here?

Overacre, Abigail E., Kurtulus, Sema, Sznol, Mario, Pardoll, Drew M., Anderson, Ana, Vignali, Dario A. A.

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 386 KB

english, 2015

26

A new paradigm for tumor immune escape: β-catenin-driven immune exclusion

Spranger, Stefani, Gajewski, Thomas F.

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 374 KB

english, 2015

27

Combination immunotherapy with α-CTLA-4 and α-PD-L1 antibody blockade prevents immune escape and leads to complete control of metastatic osteosarcoma

Lussier, Danielle M, Johnson, John L, Hingorani, Pooja, Blattman, Joseph N

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 981 KB

english, 2015

28

Preservation of tumor-host immune interactions with luciferase-tagged imaging in a murine model of ovarian cancer

Liao, John B, Ovenell, Kelsie J, Curtis, Erin E M, Cecil, Denise L, Koehnlein, Marlese R, Rastetter, Lauren R, Gad, Ekram A, Disis, Mary L

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 2.14 MB

english, 2015

29

Rapid complete response of metastatic melanoma in a patient undergoing ipilimumab immunotherapy in the setting of active ulcerative colitis

Bostwick, A Doran, Salama, April K, Hanks, Brent A

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 2.28 MB

english, 2015

30

Survivin-specific CD4+ T cells are decreased in patients with survivin-positive myeloma

Locke, Frederick L, Menges, Meghan, Veerapathran, Anandharaman, Coppola, Domenico, Gabrilovich, Dmitry, Anasetti, Claudio

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2015

31

Safety and efficacy of ipilimumab to treat advanced melanoma in the setting of liver transplantation

Morales, Rita E, Shoushtari, Alexander N, Walsh, Michelle M, Grewal, Priya, Lipson, Evan J, Carvajal, Richard D

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 974 KB

english, 2015

32

Self-adjuvanted mRNA vaccination in advanced prostate cancer patients: a first-in-man phase I/IIa study

Kübler, Hubert, Scheel, Birgit, Gnad-Vogt, Ulrike, Miller, Kurt, Schultze-Seemann, Wolfgang, vom Dorp, Frank, Parmiani, Giorgio, Hampel, Christian, Wedel, Steffen, Trojan, Lutz, Jocham, Dieter, Maurer

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2015

33

Peripheral T cell receptor diversity is associated with clinical outcomes following ipilimumab treatment in metastatic melanoma

Postow, Michael A., Manuel, Manuarii, Wong, Phillip, Yuan, Jianda, Dong, Zhiwan, Liu, Cailian, Perez, Solène, Tanneau, Isabelle, Noel, Marlène, Courtier, Anaïs, Pasqual, Nicolas, Wolchok, Jedd D.

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 549 KB

english, 2015

34

Immune modulating effects of cyclophosphamide and treatment with tumor lysate/CpG synergize to eliminate murine neuroblastoma

Gershan, Jill A., Barr, Kristen M., Weber, James J., Jing, Weiqing, Johnson, Bryon D.

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 2.35 MB

english, 2015

35

Immune monitoring technology primer: the enzyme-linked immunospot (Elispot) and Fluorospot assay

Janetzki, Sylvia

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 510 KB

english, 2015

36

Immune monitoring technology primer: Single Cell Network Profiling (SCNP)

Hawtin, Rachael E., Cesano, Alessandra

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 1.51 MB

english, 2015

37

Route of antigen delivery impacts the immunostimulatory activity of dendritic cell-based vaccines for hepatocellular carcinoma

Pardee, Angela D., Yano, Hiroshi, Weinstein, Aliyah M., Ponce, Aaron A. K., Ethridge, Alexander D., Normolle, Daniel P., Vujanovic, Lazar, Mizejewski, Gerald J., Watkins, Simon C., Butterfield, Lisa H

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 3.71 MB

english, 2015

38

Update on checkpoint blockade therapy for lymphoma

Kline, Justin, Bishop, Michael R.

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 197 KB

english, 2015

39

Baseline circulating IL-17 predicts toxicity while TGF-β1 and IL-10 are prognostic of relapse in ipilimumab neoadjuvant therapy of melanoma

Tarhini, Ahmad A., Zahoor, Haris, Lin, Yan, Malhotra, Usha, Sander, Cindy, Butterfield, Lisa H., Kirkwood, John M.

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 486 KB

english, 2015

40

Increased CTLA-4+T cells and an increased ratio of monocytes with loss of class II (CD14+ HLA-DRlo/neg) found in aggressive pediatric sarcoma patients

Hingorani, Pooja, Maas, Mary L., Gustafson, Michael P., Dickman, Paul, Adams, Roberta H., Watanabe, Masayo, Eshun, Francis, Williams, James, Seidel, Matthew J., Dietz, Allan B.

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2015

41

Intrathecal trastuzumab: immunotherapy improves the prognosis of leptomeningeal metastases in HER-2+ breast cancer patient

Lu, Nu T., Raizer, Jeffrey, Gabor, Erwin P., Liu, Natalie M., Vu, James Q., Slamon, Dennis J., Barstis, John L.

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 921 KB

english, 2015

42

Immune monitoring technology primer: flow and mass cytometry

Maecker, Holden T., Harari, Alexandre

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2015

43

Immune monitoring technology primer: clinical validation for predictive markers

Dobbin, Kevin K.

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 536 KB

english, 2015

44

nCounter®PanCancer Immune Profiling Panel (NanoString Technologies, Inc., Seattle, WA)

Cesano, Alessandra

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 625 KB

english, 2015

45

Introducing the clinical trials monitor: a new section of the journal for immunotherapy of cancer

Emens, Leisha A., Romero, Pedro

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 340 KB

english, 2015

46

A quantitative analysis of therapeutic cancer vaccines in phase 2 or phase 3 trial

Tan, Amabel CL, Goubier, Anne, Kohrt, Holbrook E.

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2015

47

Targeting the indoleamine 2,3-dioxygenase pathway in cancer

Moon, Yong Wha, Hajjar, Joud, Hwu, Patrick, Naing, Aung

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 990 KB

english, 2015

48

Inhibition of the angiopoietin/Tie2 axis induces immunogenic modulation, which sensitizes human tumor cells to immune attack

Grenga, Italia, Kwilas, Anna R., Donahue, Renee N., Farsaci, Benedetto, Hodge, James W.

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 919 KB

english, 2015

49

Erratum to: Immune monitoring technology primer

Dobbin, Kevin K.

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 317 KB

english, 2015

50

The dark side of ID8-Luc2: pitfalls for luciferase tagged murine models for ovarian cancer

Baert, Thaïs, Verschuere, Tina, Van Hoylandt, Anaïs, Gijsbers, Rik, Vergote, Ignace, Coosemans, An

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 969 KB

english, 2015

51

Ipilmumab and cranial radiation in metastatic melanoma patients: a case series and review

Schoenfeld, Jonathan D., Mahadevan, Anand, Floyd, Scott R., Dyer, Michael A., Catalano, Paul J., Alexander, Brian M., McDermott, David F., Kaplan, Irving D.

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 593 KB

english, 2015

52

NK cells and CD8+ T cells cooperate to improve therapeutic responses in melanoma treated with interleukin-2 (IL-2) and CTLA-4 blockade

Kohlhapp, Frederick J, Broucek, Joseph R, Hughes, Tasha, Huelsmann, Erica J, Lusciks, Jevgenijs, Zayas, Janet P, Dolubizno, Hubert, Fleetwood, Vidyaratna A, Grin, Alisa, Hill, Graham E, Poshepny, Jose

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 2.92 MB

english, 2015

53

Enhancing the discovery and development of immunotherapies for cancer using quantitative and systems pharmacology: Interleukin-12 as a case study

Klinke, David J

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2015

54

JITC launches a new section: commentary and editorials

Capitini, Christian M., Romero, Pedro

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 375 KB

english, 2015

55

Characterization of the human T cell response to in vitro CD27 costimulation with varlilumab

Ramakrishna, Venky, Sundarapandiyan, Karuna, Zhao, Biwei, Bylesjo, Max, Marsh, Henry C., Keler, Tibor

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 2.52 MB

english, 2015

56

Multispectral imaging of formalin-fixed tissue predicts ability to generate tumor-infiltrating lymphocytes from melanoma

Feng, Zipei, Puri, Sachin, Moudgil, Tarsem, Wood, William, Hoyt, Clifford C., Wang, Chichung, Urba, Walter J., Curti, Brendan D., Bifulco, Carlo B., Fox, Bernard A.

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 2.95 MB

english, 2015

57

Cetuximab ameliorates suppressive phenotypes of myeloid antigen presenting cells in head and neck cancer patients

Li, Jing, Srivastava, Raghvendra M., Ettyreddy, Abhinav, Ferris, Robert L.

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 2.53 MB

english, 2015

58

Prognostic impact of circulating Her-2-reactive T-cells producing pro- and/or anti-inflammatory cytokines in elderly breast cancer patients

Bailur, Jithendra Kini, Derhovanessian, Evelyna, Gueckel, Brigitte, Pawelec, Graham

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2015