Volume 15; Issue 9

Bioorganic & Medicinal Chemistry

Volume 15; Issue 9

1

The concise synthesis of chalcone, indanone and indenone analogues of combretastatin A4

Daniel J. Kerr, Ernest Hamel, M. Katherine Jung, Bernard L. Flynn

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 285 KB

english, 2007

2

In vitro efficiency of new acridyl derivatives against Plasmodium falciparum

Lucie Guetzoyan, Florence Ramiandrasoa, Hélène Dorizon, Christine Desprez, Alexandre Bridoux, Christophe Rogier, Bruno Pradines, Martine Perrée-Fauvet

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 299 KB

english, 2007

3

Preparation of cyclic 2′,3′-carbamate derivatives of erythromycin macrolide antibiotics

Audun Heggelund, Kjell Undheim

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 253 KB

english, 2007

4

Design, synthesis, and biological evaluation of substituted-N-(thieno[2,3-b]pyridin-3-yl)-guanidines, N-(1H-pyrrolo[2,3-b]pyridin-3-yl)-guanidines, and N-(1H-indol-3-yl)-guanidines

Rajesh H. Bahekar, Mukul R. Jain, Ashish Goel, Dipam N. Patel, Vijay M. Prajapati, Arun A. Gupta, Pradip A. Jadav, Pankaj R. Patel

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 312 KB

english, 2007

5

An efficient synthesis of 3-fluoro-5-thio-xylofuranosyl nucleosides of thymine, uracil, and 5-fluorouracil as potential antitumor or/and antiviral agents

Evangelia Tsoukala, George Agelis, Jan Dolinšek, Tanja Botić, Avrelija Cencič, Dimitri Komiotis

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 168 KB

english, 2007

6

Heme oxygenase inhibition by 2-oxy-substituted 1-(1H-imidazol-1-yl)-4-phenylbutanes: Effect of halogen substitution in the phenyl ring

Gheorghe Roman, John G. Riley, Jason Z. Vlahakis, Robert T. Kinobe, James F. Brien, Kanji Nakatsu, Walter A. Szarek

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 247 KB

english, 2007

7

Studies of inclusion complexes of natural and modified cyclodextrin with (+)catechin by NMR and molecular modeling

Carolina Jullian, Sebastián Miranda, Gerald Zapata-Torres, Fernando Mendizábal, Claudio Olea-Azar

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 966 KB

english, 2007

8

First synthesis of 7α- and 7β-amino-DHEA, dehydroepiandrosterone (DHEA) analogues and preliminary evaluation of their cytotoxicity on Leydig cells and TM4 Sertoli cells

Marc-Antoine Bazin, Carine Travert, Serge Carreau, Sylvain Rault, Laïla El Kihel

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 206 KB

english, 2007

9

Amphiphilic polyether branched molecules to increase the circulation time of cationic particles

Marie Garinot, Nathalie Mignet, Celine Largeau, Johanne Seguin, Daniel Scherman, Michel Bessodes

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 988 KB

english, 2007

10

Improved automated synthesis of [18F]fluoroethylcholine as a radiotracer for cancer imaging

M. Piel, A. Bauman, R.P. Baum, S. Höhnemann, I. Klette, R. Wortmann, F. Rösch

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 316 KB

english, 2007

11

Further studies on the effect of lysine at the C-terminus of the Dmt-Tic opioid pharmacophore

Gianfranco Balboni, Valentina Onnis, Cenzo Congiu, Margherita Zotti, Yusuke Sasaki, Akihiro Ambo, Sharon D. Bryant, Yunden Jinsmaa, Lawrence H. Lazarus, Ilaria Lazzari, Claudio Trapella, Severo Salvad

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 216 KB

english, 2007

12

Synthesis and preliminary pharmacological evaluation of the four stereoisomers of (2S)-2-(2′-phosphono-3′-phenylcyclopropyl)glycine, the first class of 3′-substituted transC1′−2′-2-(2′-phosphonocyclopropyl)glycines

Maura Marinozzi, Michaela Serpi, Laura Amori, Monica Gavilan Diaz, Gabriele Costantino, Udo Meyer, Peter J. Flor, Fabrizio Gasparini, Roland Heckendorn, Rainer Kuhn, Gianluca Giorgi, Mette Brunsgaard

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 590 KB

english, 2007

13

Anticancer, neuroprotective activities and computational studies of 2-amino-1,3,4-thiadiazole based compound

Wojciech Rzeski, Joanna Matysiak, Martyna Kandefer-Szerszeń

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 577 KB

english, 2007

14

A synthetic method for diversification of the P1′ substituent in phosphinic dipeptides as a tool for exploration of the specificity of the S1′ binding pockets of leucine aminopeptidases

Stamatia Vassiliou, Metaxia Xeilari, Athanasios Yiotakis, Jolanta Grembecka, Małgorzata Pawełczak, Paweł Kafarski, Artur Mucha

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 369 KB

english, 2007

15

Synthesis of hybrid molecules of caffeine and eudistomin D and its effects on adenosine receptors

Kengo Ohshita, Haruaki Ishiyama, Koshi Oyanagi, Hiroyasu Nakata, Jun’ichi Kobayashi

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 181 KB

english, 2007

16

Synthesis and evaluation of 2-(2,6-dihalophenyl)-3-pyrimidinyl-1,3-thiazolidin-4-one analogues as anti-HIV-1 agents

Ravindra K. Rawal, Rajkamal Tripathi, S.B. Katti, Christophe Pannecouque, Erik De Clercq

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 203 KB

english, 2007

17

A novel noninvasive method for assessing glutathione-conjugate efflux systems in the brain

Toshimitsu Okamura, Tatsuya Kikuchi, Kiyoshi Fukushi, Yasushi Arano, Toshiaki Irie

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 211 KB

english, 2007

18

Synthesis of carbamate derivatives of iejimalides. Retention of normal antiproliferative activity and localization of binding in cancer cells

Dirk Schweitzer, Junyi Zhu, Gotam Jarori, Junichi Tanaka, Tatsuo Higa, V. Jo Davisson, Paul Helquist

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 322 KB

english, 2007

19

Nodulisporol and Nodulisporone, novel specific inhibitors of human DNA polymerase λ from a fungus, Nodulisporium sp.

Shinji Kamisuki, Chisato Ishimaru, Kadohiro Onoda, Isoko Kuriyama, Noriko Ida, Fumio Sugawara, Hiromi Yoshida, Yoshiyuki Mizushina

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 161 KB

english, 2007

20

Novel thyroid hormone receptor antagonists with an N-alkylated diphenylamine skeleton

Takuma Komatsu, Tomoya Hirano, Chalermkiat Songkram, Emiko Kawachi, Hiroyuki Kagechika

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 259 KB

english, 2007

21

Editorial board

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 437 KB

english, 2007

22

Graphical contents list

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 226 KB

english, 2007

23

Instructions to contributors

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 34 KB

english, 2007

24

Corrigendum to “Analgesic agents without gastric damage: Design and synthesis of structurally simple benzenesulfonanilide-type cyclooxygenase-1-selective inhibitors” [Bioorg. Med. Chem. 15 (2007) 1014–1021]

Xiaoxia Zheng, Hiroyuki Oda, Kayo Takamatsu, Yukio Sugimoto, Akihiro Tai, Eiichi Akaho, Hamed Ismail Ali, Toshiyuki Oshiki, Hiroki Kakuta, Kenji Sasaki

Journal:

Bioorganic & Medicinal Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 100 KB

english, 2007