Volume 10; Issue 2

Bioorganic & Medicinal Chemistry

Volume 10; Issue 2

1

Synthesis and cytotoxic activity of tetracenomycin d and of saintopin analogues

Philippe Martin, Stéphane Rodier, Martine Mondon, Brigitte Renoux, Bruno Pfeiffer, Pierre Renard, Alain Pierré, Jean-Pierre Gesson

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 203 KB

english, 2002

2

Non-thiol Farnesyltransferase Inhibitors: N-(4-Acylamino-3-benzoylphenyl)-4-nitrocinnamic Acid Amides

Jacek Sakowski, Isabel Sattler, Martin Schlitzer

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 155 KB

english, 2002

3

Antimicrobial and Anti-Lipase Activity of Quercetin and its C2-C16 3-O-Acyl-Esters

Maria Teresa Gatto, Serena Falcocchio, Eleonora Grippa, Gabriela Mazzanti, Lucia Battinelli, Giovanni Nicolosi, Daniela Lambusta, Luciano Saso

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 126 KB

english, 2002

4

Kinetic and Crystallographic Studies of Glucopyranosylidene Spirothiohydantoin Binding to Glycogen Phosphorylase b

Nikos G Oikonomakos, Vicky T Skamnaki, Erzsébet Ösz, László Szilágyi, László Somsák, Tibor Docsa, Béla Tóth, Pál Gergely

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 403 KB

english, 2002

5

The Synthesis and Biological Evaluation of Novel Bridging Nucleoside Analogues

Cecilia H. Marzabadi, Richard W. Franck, Raymond F. Schinazi

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 189 KB

english, 2002

6

Synthesis and cytotoxic activities of analogues of thuriferic acid

Blanca Madrigal, Pilar Puebla, Angel Ramos, Rafael Peláez, Dolores Grávalos, Esther Caballero, Manuel Medarde

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 260 KB

english, 2002

7

[1,2,4]Triazole derivatives as 5-HT1A serotonin receptor ligands

Maria Concetta Sarvà, Giuseppe Romeo, Francesco Guerrera, Mariangela Siracusa, Loredana Salerno, Filippo Russo, Alfredo Cagnotto, Mara Goegan, Tiziana Mennini

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 192 KB

english, 2002

8

Synthesis and biological activity of novel thyroid hormone analogues: 5′-aryl substituted GC-1 derivatives

Grazia Chiellini, Ngoc-Ha Nguyen, James W Apriletti, John D Baxter, Thomas S Scanlan

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 282 KB

english, 2002

9

Preparation and evaluation of the in vitro erythroid differentiation induction properties of some esters of methyl 3,4-O-isopropylidene-β-d-galactopyranoside and 2,3-O-isopropylidene-d-mannofuranose

Giorgio Catelani, Felicia D'Andrea, Ettore Mastrorilli, Nicoletta Bianchi, Cristiano Chiarabelli, Monica Borgatti, Dino Martello, Roberto Gambari

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 150 KB

english, 2002

10

Synthesis and biological activity of new 1,4-benzodioxan-arylpiperazine derivatives. Further validation of a pharmacophore model for α1-adrenoceptor antagonists

Roberta Barbaro, Laura Betti, Maurizio Botta, Federico Corelli, Gino Giannaccini, Laura Maccari, Fabrizio Manetti, Giovannella Strappaghetti, Stefano Corsano

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 319 KB

english, 2002

11

Synthesis and biological evaluation of new 4-arylpiperidines and 4-aryl-4-piperidinols: dual Na+ and Ca2+ channel blockers with reduced affinity for dopamine D2 receptors

Hirokazu Annoura, Kyoko Nakanishi, Mayumi Uesugi, Atsuko Fukunaga, Seiichi Imajo, Atsuko Miyajima, Yoshiko Tamura-Horikawa, Shigeki Tamura

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 275 KB

english, 2002

12

Syntheses of fused heterocyclic compounds and their inhibitory activities for squalene synthase

Takashi Miki, Masakuni Kori, Akira Fujishima, Hiroshi Mabuchi, Ryu-ichi Tozawa, Masahira Nakamura, Yasuo Sugiyama, Hidefumi Yukimasa

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 408 KB

english, 2002

13

Novel 4,1-benzoxazepine derivatives with potent squalene synthase inhibitory activities

Takashi Miki, Masakuni Kori, Hiroshi Mabuchi, Hiroshi Banno, Ryu-ichi Tozawa, Masahira Nakamura, Shigekazu Itokawa, Yasuo Sugiyama, Hidefumi Yukimasa

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 271 KB

english, 2002

14

Clustered ergot alkaloids modulate cell-mediated cytotoxicity

Vladimı́r Křen, Anna Fišerová, Lenka Weignerová, Ivan Stibor, Petr Halada, Věra Přikrylová, Petr Sedmera, Miloslav Pospı́šil

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 183 KB

english, 2002

15

Synthesis of dipeptide-bound epoxides and α,β-unsaturated amides as potential irreversible transglutaminase inhibitors

Pierre de Macédo, Claudio Marrano, Jeffrey W Keillor

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 138 KB

english, 2002

16

5-Phenyl substituted 1-methyl-2-pyridones and 4′-substituted biphenyl-4-carboxylic acids. synthesis and evaluation as inhibitors of steroid-5α-reductase type 1 and 2

Franck Picard, Tobias Schulz, Rolf W. Hartmann

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 218 KB

english, 2002

17

Antimicrobial and antitumor activity of n-heteroimmine-1,2,3-dithiazoles and their transformation in triazolo-, imidazo-, and pyrazolopirimidines

Pier Giovanni Baraldi, Maria Giovanna Pavani, Maria del Carmen Nuñez, Patrizia Brigidi, Beatrice Vitali, Roberto Gambari, Romeo Romagnoli

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 164 KB

english, 2002

18

Stereoselective synthesis of 2-amino-3-fluoro bicyclo[3.1.0]hexane-2,6-dicarboxylic acid

Concepción Pedregal, William Prowse

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 122 KB

english, 2002

19

A mercapto analogue of 5′-noraristeromycin

Subha R Das, Stewart W Schneller, Jan Balzarini, Erik De Clercq

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 117 KB

english, 2002

20

Recognition of Nine Base Pair Sequences in the Minor Groove of DNA at Subpicomolar Concentrations by a Novel Microgonotropen

Alexander L Satz, Thomas C Bruice

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 377 KB

english, 2002

21

Synthesis of alkenyldiarylmethane (ADAM) non-Nucleoside HIV-1 reverse transcriptase inhibitors with non-Identical aromatic rings

Guozhang Xu, Tracy L. Hartman, Heather Wargo, Jim A. Turpin, Robert W. Buckheit Jr., Mark Cushman

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 177 KB

english, 2002

22

Synthesis of a 3-methyluridine phosphoramidite to investigate the role of methylation in a ribosomal RNA hairpin

Helen M.-P Chui, May Meroueh, Stephen A Scaringe, Christine S Chow

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 211 KB

english, 2002

23

Conformationally restricted TRH analogues: Constraining the pyroglutamate region

Jill C. Simpson, Chris Ho, E.F. Berkley Shands, Marvin C. Gershengorn, Garland R. Marshall, Kevin D. Moeller

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 285 KB

english, 2002

24

ω-(Imidazol-4-yl)alkane-1-sulfonamides: a new series of potent histamine H3 receptor antagonists

Matthew J. Tozer, Ildiko M. Buck, Tracey Cooke, S.Barret Kalindjian, Michael J. Pether, Katherine I.M. Steel

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 168 KB

english, 2002

25

Graphical Abstracts

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 223 KB

english, 2002