Volume 39; Issue 14

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Biochemistry
Volume 39; Issue 14

Biochemistry

Volume 39; Issue 14

1

A Common Pharmacophore for Taxol and the Epothilones Based on the Biological Activity of a Taxane Molecule Lacking a C-13 Side Chain †

He, Lifeng, Jagtap, Prakash G., Kingston, David G. I., Shen, Heng-Jia, Orr, George A., Horwitz, Susan Band

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 234 KB

english, 2000

2

Deletion of C-Terminal Residues of Escherichia coli Ribosomal Protein L10 Causes the Loss of Binding of One L7/L12 Dimer: Ribosomes with One L7/L12 Dimer Are Active †

Griaznova, Olga, Traut, Robert R.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 80 KB

english, 2000

3

Structural and Dynamic Characterization of ω-Conotoxin MVIIA: The Binding Loop Exhibits Slow Conformational Exchange †,‡

Atkinson, R. Andrew, Kieffer, Bruno, Dejaegere, Annick, Sirockin, Finton, Lefèvre, Jean-François

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 298 KB

english, 2000

4

Purification, Characterization, and Preliminary Crystallographic Study of Copper-Containing Nitrous Oxide Reductase from Pseudomonas nautica 617 †

Prudêncio, Miguel, Pereira, Alice S., Tavares, Pedro, Besson, Stéphane, Cabrito, Inês, Brown, Kieron, Samyn, Bart, Devreese, Bart, Van Beeumen, Jozef, Rusnak, Frank, Fauque, Guy, Moura, José J. G., Te

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 392 KB

english, 2000

5

Strand Cleavage of Supercoiled DNA by Water-Soluble Peroxyl Radicals. The Overlooked Importance of Peroxyl Radical Charge †

Paul, Thomas, Young, Mary Jane, Hill, Irene E., Ingold, K. U.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 72 KB

english, 2000

6

A Partially Unfolded Structure of the Alkaline-Denatured State of Pepsin and Its Implication for Stability of the Zymogen-Derived Protein

Konno, Takashi, Kamatari, Yuji O., Tanaka, Naoki, Kamikubo, Hironari, Dobson, Christopher M., Nagayama, Kuniaki

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 102 KB

english, 2000

7

Iron-Sulfur Center of Biotin Synthase and Lipoate Synthase

Ollagnier-de Choudens, Sandrine, Sanakis, Yiannis, Hewitson, Kirsty S., Roach, Peter, Baldwin, Jack E., Münck, Eckard, Fontecave, Marc

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 108 KB

english, 2000

8

Lipases Provide a New Mechanistic Model for Polyhydroxybutyrate (PHB) Synthases: Characterization of the Functional Residues in Chromatium vinosum PHB Synthase †

Jia, Yong, Kappock, T. Joseph, Frick, Tobias, Sinskey, Anthony J., Stubbe, JoAnne

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 284 KB

english, 2000

9

Proton NMR Studies of Co(II) Complexes of the Peptide Antibiotic Bacitracin and Analogues: Insight into Structure−Activity Relationship

Epperson, Jon D., Ming, Li-June

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 124 KB

english, 2000

10

Magnetic Circular Dichroism Properties of Reaction Center Complexes Isolated from the Zinc-Bacteriochlorophyll a -containing Purple Bacterium Acidiphilium rubrum †

Mimuro, Mamoru, Kobayashi, Masayuki, Shimada, Keizo, Uezono, Katsuhisa, Nozawa, Tsunenori

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 109 KB

english, 2000

11

Oxidase Reaction of Cytochrome cd 1 from Paracoccus pantotrophus †

Koppenhöfer, Alrik, Little, Richard H., Lowe, David J., Ferguson, Stuart J., Watmough, Nicholas J.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 102 KB

english, 2000

12

Yeast Resolving Enzyme CCE1 Makes Sequential Cleavages in DNA Junctions within the Lifetime of the Complex †

Fogg, Jonathan M., Schofield, Mark J., Déclais, Anne-Cécile, Lilley, David M. J.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 148 KB

english, 2000

13

Calmodulin Remains Extended upon Binding to Smooth Muscle Caldesmon: A Combined Small-Angle Scattering and Fourier Transform Infrared Spectroscopy Study †

Krueger, Joanna K., Gallagher, Stephen C., Wang, C.-L. Albert, Trewhella, Jill

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 298 KB

english, 2000

14

Characterization of the DNA-Binding Domains from the Yeast Cell-Cycle Transcription Factors Mbp1 and Swi4

Taylor, Ian A., McIntosh, Pauline B., Pala, Preshna, Treiber, Monika K., Howell, Steven, Lane, Andrew N., Smerdon, Stephen J.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 479 KB

english, 2000

15

The Crystal Structure of N 10 -Formyltetrahydrofolate Synthetase from Moorella thermoacetica †,‡

Radfar, Ramin, Shin, Ronald, Sheldrick, George M., Minor, Wladek, Lovell, Charles R., Odom, Jerome D., Dunlap, R. Bruce, Lebioda, Lukasz

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 784 KB

english, 2000

16

Evidence That β-Tubulin Induces a Conformation Change in the Cytosolic Chaperonin Which Stabilizes Binding: Implications for the Mechanism of Action †,‡

Dobrzynski, Jane K., Sternlicht, Mona L., Peng, Isaac, Farr, George W., Sternlicht, Himan

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 334 KB

english, 2000

17

Structure of the Complex of Cdc42Hs with a Peptide Derived from P-21 Activated Kinase †,⊥

Gizachew, Dawit, Guo, Wei, Chohan, Kamaldeep K., Sutcliffe, Michael J., Oswald, Robert E.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 602 KB

english, 2000

18

Mapping the Oligomeric Interface of Diacylglycerol Kinase by Engineered Thiol Cross-Linking: Homologous Sites in the Transmembrane Domain †

Nagy, Joanna K., Lau, Francis W., Bowie, James U., Sanders, Charles R.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 222 KB

english, 2000

19

Function of the Extra 5‘-Phosphate Carried by Histidine tRNA

Fromant, Michel, Plateau, Pierre, Blanquet, Sylvain

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 50 KB

english, 2000

20

Studies with Recombinant Saccharomyces cerevisiae CaaX Prenyl Protease Rce1p †

Dolence, Julia M., Steward, Lance E., Dolence, E. Kurt, Wong, Darren H., Poulter, C. Dale

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 222 KB

english, 2000

21

Interaction of a Semirigid Agonist with Torpedo Acetylcholine Receptor †

Kawai, Hideki, Cao, Liren, Dunn, Susan M. J., Dryden, William F., Raftery, Michael A.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 120 KB

english, 2000

22

Using a Targeted Chemical Nuclease To Elucidate Conformational Changes in the E. coli 30S Ribosomal Subunit †

Muth, Gregory W., Hennelly, Scott P., Hill, Walter E.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 192 KB

english, 2000

23

Roles of Aromatic Residues in High Interfacial Activity of Naja naja atra Phospholipase A 2

Sumandea, Marius, Das, Sudipto, Sumandea, Claudia, Cho, Wonhwa

Journal:

Année:

2000

Fichier:

PDF, 8 KB

2000

24

Physical Constraints in the Condensation of Eukaryotic Chromosomes. Local Concentration of DNA versus Linear Packing Ratio in Higher Order Chromatin Structures †

Daban, Joan-Ramon

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 42 KB

english, 2000

25

Electron Paramagnetic Resonance and Electron Nuclear Double Resonance Spectroscopic Identification and Characterization of the Tyrosyl Radicals in Prostaglandin H Synthase 1 †

Shi, Wenjun, Hoganson, Curtis W., Espe, Matthew, Bender, Christopher J., Babcock, Gerald T., Palmer, Graham, Kulmacz, Richard J., Tsai, Ah-lim

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 116 KB

english, 2000

26

On the Role of the Carboxyl-Terminal Helix of RXR in the Interactions of the Receptor with Ligand †

Budhu, Anuradha S., Noy, Noa

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 61 KB

english, 2000

27

Overexpression, Purification, and Analysis of Complementation Behavior of E. coli SuhB Protein: Comparison with Bacterial and Archaeal Inositol Monophosphatases †

Chen, Liangjing, Roberts, Mary F.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 161 KB

english, 2000

28

Histidine 295 and Histidine 510 Are Crucial for the Enzymatic Degradation of Heparan Sulfate by Heparinase III †

Pojasek, Kevin, Shriver, Zachary, Hu, Yini, Sasisekharan, Ram

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 79 KB

english, 2000

29

Conservative Mutations of Glutamine-125 in Herpes Simplex Virus Type 1 Thymidine Kinase Result in a Ganciclovir Kinase with Minimal Deoxypyrimidine Kinase Activities †

Hinds, Trenton A., Compadre, Cesar, Hurlburt, Barry K., Drake, Richard R.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 104 KB

english, 2000

30

Do Cysteine 230 and Lysine 238 of Biotin Carboxylase Play a Role in the Activation of Biotin? †

Levert, Keith L., Lloyd, Robert B., Waldrop, Grover L.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 61 KB

english, 2000

31

New Mechanistic Insights from Structural Studies of the Oxygen-Sensing Domain of Bradyrhizobium japonicum FixL †,‡

Gong, Weimin, Hao, Bing, Chan, Michael K.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 347 KB

english, 2000

32

NEM Tubulin Inhibits Microtubule Minus End Assembly by a Reversible Capping Mechanism †

Phelps, K. K., Walker, R. A.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 97 KB

english, 2000

33

Factors Determining Mutagenic Potential for Individual Cis and Trans Opened Benzo[ c ]phenanthrene Diol Epoxide-Deoxyadenosine Adducts †

Pontén, Ingrid, Sayer, Jane M., Pilcher, Anthony S., Yagi, Haruhiko, Kumar, Subodh, Jerina, Donald M., Dipple, Anthony

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 190 KB

english, 2000

34

Coupling between the N- and C-Terminal Domains Influences Transducin-α Intrinsic GDP/GTP Exchange †

Muradov, Khakim G., Artemyev, Nikolai O.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 194 KB

english, 2000

35

Environmental Study of Subunit i , a F o Component of the Yeast ATP Synthase †

Paumard, Patrick, Vaillier, Jacques, Napias, Christian, Arselin, Geneviève, Brèthes, Daniel, Graves, Pierre-Vincent, Velours, Jean

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 187 KB

english, 2000

36

Structure of the Molybdenum Site of Rhodobacter sphaeroides Biotin Sulfoxide Reductase †

Temple, Carrie A., George, Graham N., Hilton, James C., George, Martin J., Prince, Roger C., Barber, Michael J., Rajagopalan, K. V.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 77 KB

english, 2000

37

Mutation of Serine 395 of Tyrosine Hydroxylase Decouples Oxygen−Oxygen Bond Cleavage and Tyrosine Hydroxylation †

Ellis, Holly R., Daubner, S. Colette, Fitzpatrick, Paul F.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 96 KB

english, 2000

38

Coordination Chemistry of Co(II)-Bleomycin: Its Investigation through NMR and Molecular Dynamics †,‡

Lehmann, Teresa E., Serrano, Maria Luisa, Que, Lawrence

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 383 KB

english, 2000

39

Intramolecular Activation of a Ca 2+ -Dependent Protein Kinase Is Disrupted by Insertions in the Tether That Connects the Calmodulin-like Domain to the Kinase †

Vitart, Veronique, Christodoulou, John, Huang, Jing-Feng, Chazin, Walter J., Harper, Jeffrey F.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 121 KB

english, 2000

40

Structure and Stability Effects of the Mutation of Glycine 34 to Serine in Rhodobacter capsulatus Cytochrome c 2†

Zhao, Dezheng, Hutton, Harold M., Meyer, Terrance E., Walker, F. Ann, MacKenzie, Neil E., Cusanovich, Michael A.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 126 KB

english, 2000

41

Interaction of Soluble Guanylate Cyclase with YC-1: Kinetic and Resonance Raman Studies †

Denninger, John W., Schelvis, Johannes P. M., Brandish, Philip E., Zhao, Yunde, Babcock, Gerald T., Marletta, Michael A.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 90 KB

english, 2000