Toxicology and Applied Pharmacology

1

Predicting chemically-induced skin reactions. Part I: QSAR models of skin sensitization and their application to identify potentially hazardous compounds

Alves, Vinicius M., Muratov, Eugene, Fourches, Denis, Strickland, Judy, Kleinstreuer, Nicole, Andrade, Carolina H., Tropsha, Alexander

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1019 KB

english, 2015

2

In vitro biotransformation of tris(2-butoxyethyl) phosphate (TBOEP) in human liver and serum

Van den Eede, Nele, Erratico, Claudio, Exarchou, Vassiliki, Maho, Walid, Neels, Hugo, Covaci, Adrian

Journal:

Toxicology and Applied Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 549 KB

english, 2015

3

A rat model of nerve agent exposure applicable to the pediatric population: The anticonvulsant efficacies of atropine and GluK1 antagonists

Miller, Steven L., Aroniadou-Anderjaska, Vassiliki, Figueiredo, Taiza H., Prager, Eric M., Almeida-Suhett, Camila P., Apland, James P., Braga, Maria F.M.

Journal:

Toxicology and Applied Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 2.99 MB

english, 2015

4

Quaternary and tertiary aldoxime antidotes for organophosphate exposure in a zebrafish model system

Schmidt, Hayden R., Radić, Zoran, Taylor, Palmer, Fradinger, Erica A.

Journal:

Toxicology and Applied Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 814 KB

english, 2015

5

Metformin inhibits 7,12-dimethylbenz[a]anthracene-induced breast carcinogenesis and adduct formation in human breast cells by inhibiting the cytochrome P4501A1/aryl hydrocarbon receptor signaling pathway

Maayah, Zaid H., Ghebeh, Hazem, Alhaider, Abdulqader A., El-Kadi, Ayman O.S., Soshilov, Anatoly A., Denison, Michael S., Ansari, Mushtaq Ahmad, Korashy, Hesham M.

Journal:

Toxicology and Applied Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2015

6

Paradoxically, iron overload does not potentiate doxorubicin-induced cardiotoxicity in vitro in cardiomyocytes and in vivo in mice

Guenancia, Charles, Li, Na, Hachet, Olivier, Rigal, Eve, Cottin, Yves, Dutartre, Patrick, Rochette, Luc, Vergely, Catherine

Journal:

Toxicology and Applied Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 2.12 MB

english, 2015

7

Regulation of ozone-induced lung inflammation and injury by the β-galactoside-binding lectin galectin-3

Sunil, Vasanthi R., Francis, Mary, Vayas, Kinal N., Cervelli, Jessica A., Choi, Hyejeong, Laskin, Jeffrey D., Laskin, Debra L.

Journal:

Toxicology and Applied Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 2.89 MB

english, 2015

8

Characterizing the mechanism of thiazolidinedione-induced hepatotoxicity: An in vitro model in mitochondria

Hu, Dan, Wu, Chun-qi, Li, Ze-jun, Liu, Yue, Fan, Xing, Wang, Quan-jun, Ding, Ri-gao

Journal:

Toxicology and Applied Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 1.83 MB

english, 2015

9

Developmental exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin alters DNA methyltransferase (dnmt) expression in zebrafish (Danio rerio)

Aluru, Neelakanteswar, Kuo, Elaine, Helfrich, Lily W., Karchner, Sibel I., Linney, Elwood A., Pais, June E., Franks, Diana G.

Journal:

Toxicology and Applied Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 644 KB

english, 2015

10

Developmental bisphenol A (BPA) exposure leads to sex-specific modification of hepatic gene expression and epigenome at birth that may exacerbate high-fat diet-induced hepatic steatosis

Strakovsky, Rita S., Wang, Huan, Engeseth, Nicki J., Flaws, Jodi A., Helferich, William G., Pan, Yuan-Xiang, Lezmi, Stéphane

Journal:

Toxicology and Applied Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 2.19 MB

english, 2015

11

Combination effects of AHR agonists and Wnt/β-catenin modulators in zebrafish embryos: Implications for physiological and toxicological AHR functions

Wincent, Emma, Stegeman, John J., Jönsson, Maria E.

Journal:

Toxicology and Applied Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 2.95 MB

english, 2015

12

Sodium meta-arsenite prevents the development of autoimmune diabetes in NOD mice

Lee, Y.S., Kim, D., Lee, E.K., Kim, S., Choi, C.S., Jun, H.S.

Journal:

Toxicology and Applied Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 979 KB

english, 2015

13

The imperatorin derivative OW1, a new vasoactive compound, inhibits VSMC proliferation and extracellular matrix hyperplasia

Zhou, Nan, Zhang, Yu, Wang, Tao, He, Jianyu, He, Huaizhen, He, Langchong

Journal:

Toxicology and Applied Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 1.98 MB

english, 2015

14

A novel synthetic derivative of melatonin, 5-hydroxy-2’-isobutyl-streptochlorin (HIS), inhibits inflammatory responses via regulation of TRIF-dependent signaling and inflammasome activation

Shim, Do-Wan, Shin, Hee Jae, Han, Ji-Won, Ji, Young-Eun, Jang, Cheol-Hun, Koppula, Sushruta, Kang, Tae-Bong, Lee, Kwang-Ho

Journal:

Toxicology and Applied Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2015

15

Predicting chemically-induced skin reactions. Part II: QSAR models of skin permeability and the relationships between skin permeability and skin sensitization

Alves, Vinicius M., Muratov, Eugene, Fourches, Denis, Strickland, Judy, Kleinstreuer, Nicole, Andrade, Carolina H., Tropsha, Alexander

Journal:

Toxicology and Applied Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 675 KB

english, 2015

16

Honokiol activates the LKB1–AMPK signaling pathway and attenuates the lipid accumulation in hepatocytes

Seo, Min Suk, Kim, Jung Hwan, Kim, Hye Jung, Chang, Ki Churl, Park, Sang Won

Journal:

Toxicology and Applied Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 2.94 MB

english, 2015

17

Editorial Boar

Journal:

Toxicology and Applied Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 34 KB

english, 2015

18

Sex-related differences in murine hepatic transcriptional and proteomic responses to TCDD

Prokopec, Stephenie D., Watson, John D., Lee, Jamie, Pohjanvirta, Raimo, Boutros, Paul C.

Journal:

Toxicology and Applied Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2015

20

Potential of extracellular microRNAs as biomarkers of acetaminophen toxicity in children

Yang, Xi, Salminen, William F., Shi, Qiang, Greenhaw, James, Gill, Pritmohinder S., Bhattacharyya, Sudeepa, Beger, Richard D., Mendrick, Donna L., Mattes, William B., James, Laura P.

Journal:

Toxicology and Applied Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2015

Volume 284; Issue 2

Predicting chemically-induced skin reactions. Part I: QSAR models of skin sensitization and their application to identify potentially hazardous compounds

In vitro biotransformation of tris(2-butoxyethyl) phosphate (TBOEP) in human liver and serum

A rat model of nerve agent exposure applicable to the pediatric population: The anticonvulsant efficacies of atropine and GluK1 antagonists

Quaternary and tertiary aldoxime antidotes for organophosphate exposure in a zebrafish model system

Metformin inhibits 7,12-dimethylbenz[a]anthracene-induced breast carcinogenesis and adduct formation in human breast cells by inhibiting the cytochrome P4501A1/aryl hydrocarbon receptor signaling pathway

Paradoxically, iron overload does not potentiate doxorubicin-induced cardiotoxicity in vitro in cardiomyocytes and in vivo in mice

Regulation of ozone-induced lung inflammation and injury by the β-galactoside-binding lectin galectin-3

Characterizing the mechanism of thiazolidinedione-induced hepatotoxicity: An in vitro model in mitochondria

Developmental exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin alters DNA methyltransferase (dnmt) expression in zebrafish (Danio rerio)

Developmental bisphenol A (BPA) exposure leads to sex-specific modification of hepatic gene expression and epigenome at birth that may exacerbate high-fat diet-induced hepatic steatosis

Combination effects of AHR agonists and Wnt/β-catenin modulators in zebrafish embryos: Implications for physiological and toxicological AHR functions

Sodium meta-arsenite prevents the development of autoimmune diabetes in NOD mice

The imperatorin derivative OW1, a new vasoactive compound, inhibits VSMC proliferation and extracellular matrix hyperplasia

A novel synthetic derivative of melatonin, 5-hydroxy-2’-isobutyl-streptochlorin (HIS), inhibits inflammatory responses via regulation of TRIF-dependent signaling and inflammasome activation

Predicting chemically-induced skin reactions. Part II: QSAR models of skin permeability and the relationships between skin permeability and skin sensitization

Honokiol activates the LKB1–AMPK signaling pathway and attenuates the lipid accumulation in hepatocytes

Editorial Boar

TOC

Sex-related differences in murine hepatic transcriptional and proteomic responses to TCDD

Potential of extracellular microRNAs as biomarkers of acetaminophen toxicity in children