Volume 233; Issue 1-3

Main
Toxicology
Volume 233; Issue 1-3

Toxicology

Volume 233; Issue 1-3

1

Cholinergic modulation of normal and epileptiform activity in cortico-striatal networks in vitro

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 57 KB

english, 2007

2

Transcription factor NF-κB as mediator of sulfur mustard induced damage of the skin

Bernd Rebholz, Kai Kehe, Rudolf A. Rupec

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 51 KB

english, 2007

3

Do we need an extended use of 2-PAM in a severe organophosphate intoxication?

H.K. Roh, W.H. Um, J.S. Kim

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 59 KB

english, 2007

4

Analysis of matrix metalloproteinase expression in different types of skin and lung cells after exposure to sulfur mustard

Tanja Popp, Virginia Egea, Kai Kehe, Marianne Jochum, Christian Ries

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 49 KB

english, 2007

5

Synthesis of glucoconjugates with heterocyclic oximes

R. Odžak, M. Oršulić, S. Tomić

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 118 KB

english, 2007

6

Electrical detection of AChE activity using cell free electrophysiology

Petr Obrdlik, Anja Knecht, Ingo Janausch, Béla Kelety

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 109 KB

english, 2007

7

Do oximes enhance the spontaneous reactivation of pyridostigmine inhibited acetylcholinesterase in the presence of soman inhibition?

Yee Peng Lue, Weng Keong Loke

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 118 KB

english, 2007

8

Atropine degradation products and trace heavy metal content in AtroPen® and ComboPen® auto-injectors

Michael Loch, Thomas Zimmermann

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 60 KB

english, 2007

9

Nanoparticulate systems for brain delivery of oximes: First loading studies

Jürgen Kufleitner, Jürgen Hermanns, Hagen von Briesen, Jörg Kreuter

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 62 KB

english, 2007

10

Development of a human co-culture model of a bronchial unit in vitro to investigate toxic pathomechanisms

M. Iris Hermanns, Fernando Bittinger, Michaela Bock, Sabine Fuchs, C. James Kirkpatrick

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 62 KB

english, 2007

11

Effects of sulfur mustard on fibroblast and keratinocyte co-cultures

K. Kehe, J. Schneider, J. Emmler, H. Kreppel, M. Abend, L. Szinicz

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 65 KB

english, 2007

12

Novel hybrid acetylcholinesterase inhibitors: Synthesis, docking and inhibition studies

P.W. Elsinghorst, M. Gütschow

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 96 KB

english, 2007

13

Towards optimization of high-throughput methods for assessing genotoxic damage by carcinogenic chemicals or ionizing radiation

M. Debiak, M. Moreno-Villanueva, T. Sindlinger, A. Bürkle

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 52 KB

english, 2007

14

In vitro interactions between pyridinium aldoximes and endogenous bio-scavenger butyrylcholinesterase in tabun poisoning

Maja Čalić, Zrinka Kovarik

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 58 KB

english, 2007

15

Functional quality testing of Bundeswehr autoinjectors: AtroPen®, ComboPen® and morphine autoinjectors

Thomas Zimmermann, Kornelia Eggert-Bury

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 53 KB

english, 2007

16

Evaluation of HI 6 treatment after percutaneous VR exposure by use of a kinetic-based dynamic computer model

N. Aurbek, H. Thiermann, L. Szinicz, F. Worek

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 376 KB

english, 2007

17

Development of antidotes: Problems and strategies

Ladislaus Szinicz, Franz Worek, Horst Thiermann, Kai Kehe, Saskia Eckert, Peter Eyer

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 621 KB

english, 2007

18

Evaluation of monoquaternary pyridinium oximes potency to reactivate tabun-inhibited human acetylcholinesterase

Renata Odžak, Maja Čalić, Tomica Hrenar, Ines Primožič, Zrinka Kovarik

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 895 KB

english, 2007

19

Adaptive changes in acetylcholinesterase gene expression as mediators of recovery from chemical and biological insults

Tama Evron, David Greenberg, Tsafrir S. Mor, Hermona Soreq

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 905 KB

english, 2007

20

Cholinergic modulation of periaqueductal grey neurons: Does it contribute to epileptogenesis after organophosphorus nerve agent intoxication?

Mitsuru Sanada, Fang Zheng, Tobias Huth, Christian Alzheimer

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 585 KB

english, 2007

21

Mutation of acetylcholinesterase to enhance oxime-assisted catalytic turnover of methylphosphonates

Zrinka Kovarik, Zoran Radić, Harvey A. Berman, Palmer Taylor

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 445 KB

english, 2007

22

Testing of antidotes for organophosphorus compounds: Experimental procedures and clinical reality

Peter Eyer, Ladislaus Szinicz, Horst Thiermann, Franz Worek, Thomas Zilker

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 740 KB

english, 2007

23

Medical countermeasures to WMDs: Defence research for civilian and military use

Murray G. Hamilton, Paul M. Lundy

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 119 KB

english, 2007

24

Polyethylene-glycol conjugated recombinant human acetylcholinesterase serves as an efficacious bioscavenger against soman intoxication

Chanoch Kronman, Ofer Cohen, Lily Raveh, Ohad Mazor, Arie Ordentlich, Avigdor Shafferman

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 316 KB

english, 2007

25

Human paraoxonase: A promising approach for pre-treatment and therapy of organophosphorus poisoning

Daniel Rochu, Eric Chabrière, Patrick Masson

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2007

26

Problems in the supply of antidotes—A view from the pharmaceutical industry

Johann Ruprecht

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 82 KB

english, 2007

27

Anaesthesia in patients suffering from organophosphorus intoxication—interactions between general anaesthetics and acetylcholine in cortical networks in vitro

Christian Grasshoff, Horst Thiermann, Bernd Antkowiak

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 374 KB

english, 2007

28

In memory of Ilse Hagedorn

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 203 KB

english, 2007

29

Asymmetric fluorogenic organophosphates for the development of active organophosphate hydrolases with reversed stereoselectivity

Gabi Amitai, Rellie Adani, Guy Yacov, Shelly Yishay, Shai Teitlboim, Liat Tveria, Osnat Limanovich, Moshe Kushnir, Haim Meshulam

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

30

Lessons to be learnt from organophosphorus pesticide poisoning for the treatment of nerve agent poisoning

H. Thiermann, L. Szinicz, P. Eyer, N. Felgenhauer, T. Zilker, F. Worek

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 490 KB

english, 2007

31

Sensitivity of butyrylcholinesterase knockout mice to (−)-huperzine A and donepezil suggests humans with butyrylcholinesterase deficiency may not tolerate these Alzheimer's disease drugs and indicates butyrylcholinesterase function in neurotransmission

Ellen G. Duysen, Bin Li, Sultan Darvesh, Oksana Lockridge

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 212 KB

english, 2007

32

Reevaluation of indirect field stimulation technique to demonstrate oxime effectiveness in OP-poisoning in muscles in vitro

T. Seeger, F. Worek, L. Szinicz, H. Thiermann

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 274 KB

english, 2007

33

Tenth International Medical Chemical Defence Conference 2006 “New strategies in medical protection against organophosphorus compounds”

Ladislaus Szinicz, Elsa Reiner, Peter Eyer

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 72 KB

english, 2007

34

Development of physiologically based toxicokinetic and toxicodynamic models for nerve agents

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 68 KB

english, 2007

35

Editorial Board

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 46 KB

english, 2007

36

Comparison of sulfur mustard induced mechanism of cell damage in dependency of time course and cell type

W. Bloch, A. Elischer, M. Schriek, K. Böhm, F. Moghbeli, K. Kehe, L. Szinicz, D. Steinritz

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 83 KB

english, 2007

37

Apoptotic effect of sarin on sarcoma L1 cells—In vitro study

R. Zdanowski, O. Antkowiak, T. Ołdak, M. Brytan, M. Kowalczyk

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 49 KB

english, 2007

38

Functional states, storage and thermal stability of human paraoxonase: Drawbacks, advantages and potential

Daniel Rochu, Frédérique Renault, Mikael Elias, Sophie Hanne, Cécile Cléry-Barraud, Eric Chabrière, Patrick Masson

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 49 KB

english, 2007

39

Two aging pathways for organophosphorus-inhibited human butyrylcholinesterase resolved by MALDI-TOF mass spectrometry

He Li, Florian Nachon, Lawrence M. Schopfer, Patrick Masson, Oksana Lockridge

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 51 KB

english, 2007

40

Potency of new structurally different oximes to reactivate cyclosarin inhibited-human brain acetylcholinesterases

Kamil Kuca, Jiri Cabal, Daniel Jun, Jiri Bajgar, Jiri Kassa, Josef Fusek

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 61 KB

english, 2007

41

The effect of atropine dosage on the efficacy of other pretreatment and treatment medical countermeasures for nerve agent intoxication

Irwin Koplovitz, Susan Schulz, Roy Railer, Melinda Sigler, Cristin Kelleher, Michael Shutz

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 58 KB

english, 2007

42

Development of a rapid and reliable on-site sulfur mustard detector

Sebastian Klaus, Claudia Beitsch, Marcus Scheibenzuber

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 48 KB

english, 2007

43

Phosphotriesterase modified by poly[N-(2-hydroxypropyl)methacrylamide]

Daniel Jun, Kamil Kuca, Jiri Bajgar, Martin Hruby, Jan Kucka, Frédérique Renault, Patrick Masson

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 53 KB

english, 2007

44

Effect of antioxidants on sulfur mustard-induced toxicity in an in vitro-model of the human blood–air barrier

J. Emmler, M.I. Hermanns, H. Kreppel, K. Kehe, L. Szinicz

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 108 KB

english, 2007

45

Species specific binding constants of atropine to muscarinic receptors

R. Bogan, H. Thiermann, L. Szinicz

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 49 KB

english, 2007

46

Simulation of cholinesterase status at different scenarios of nerve agent exposure

Franz Worek, Peter Eyer, Ladislaus Szinicz, Horst Thiermann

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 772 KB

english, 2007

47

Enzyme-kinetic investigation of different sarin analogues reacting with human acetylcholinesterase and butyrylcholinesterase

A. Bartling, F. Worek, L. Szinicz, H. Thiermann

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 221 KB

english, 2007

48

Development of next generation medical countermeasures to nerve agent poisoning

Janet Wetherell, Matthew Price, Helen Mumford, Stuart Armstrong, Leah Scott

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 611 KB

english, 2007

49

Reversible inhibition of acetylcholinesterase by carbamates or huperzine A increases residual activity of the enzyme upon soman challenge

Saskia Eckert, Peter Eyer, Franz Worek

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 289 KB

english, 2007

50

Swine models in the design of more effective medical countermeasures against organophosphorus poisoning

F. Dorandeu, J.R. Mikler, H. Thiermann, C. Tenn, C. Davidson, T.W. Sawyer, G. Lallement, F. Worek

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 406 KB

english, 2007

51

Acetylcholinesterase: Converting a vulnerable target to a template for antidotes and detection of inhibitor exposure

Palmer Taylor, Zrinka Kovarik, Elsa Reiner, Zoran Radić

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 408 KB

english, 2007

52

The dilemma of approving antidotes

Christian Steffen

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 135 KB

english, 2007

53

Stoichiometric and catalytic scavengers as protection against nerve agent toxicity: A mini review

David E. Lenz, David Yeung, J. Richard Smith, Richard E. Sweeney, Lucille A. Lumley, Douglas M. Cerasoli

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 432 KB

english, 2007