Volume 113; Issue 1-3

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Toxicology
Volume 113; Issue 1-3

Toxicology

Volume 113; Issue 1-3

1

Risk assessment for butadiene: introductory and summary comments

Gilbert S. Omenn

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 720 KB

english, 1996

2

Metabolism and pharmacokinetics of 1,3-butadiene

Linda S. Birnbaum, Douglas A. Keller

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 253 KB

english, 1996

3

Metabolism of 1,3-butadiene: species differences

Rogene F. Henderson, Janice R. Thornton-Manning, William E. Bechtold, Alan R. Dahl

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 476 KB

english, 1996

4

Biochemistry of 1,3-butadiene metabolism and its relevance to 1,3-butadiene-induced carcinogenicity

Adnan A. Elfarra, Renee J. Krause, Rebecca R. Selzer

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 633 KB

english, 1996

5

Effects of the structure of a toxicokinetic model of butadiene inhalation exposure on computed production of carcinogenic intermediates

Michael C. Kohn, Ronald L. Melnick

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 755 KB

english, 1996

6

PBPK model for butadiene metabolism to epoxides: quantitative species differences in metabolism

Gunnar Johanson, Johannes G. Filser

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 764 KB

english, 1996

7

Metabolism of butadiene by mice, rats, and humans: a comparison of physiologically based toxicokinetic model predictions and experimental data

James A. Bond, Matthew W. Himmelstein, Mark Seaton, Pieter Boogaard, Michele A. Medinsky

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 652 KB

english, 1996

8

Biological monitoring for mutagenic effects of occupational exposure to butadiene

Jonathan B. Ward Jr., Marinel M. Ammenheuser, Elbert B. Whorton Jr., William E. Bechtold, Karl T. Kelsey, Marvin S. Legator

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 671 KB

english, 1996

9

Biological effect monitoring in industrial workers from the Czech Republic exposed to low levels of butadiene

A.D. Tates, F.J. van Dam, F.A. de Zwart, F. Darroudi, A.T. Natarajan, P. Rössner, K. Peterková, K. Peltonen, N.A. Demopoulos, G. Stephanou, D. Vlachodimitropoulos, R.J. Srám

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 826 KB

english, 1996

10

hprt mutation frequency among workers exposed to 1,3-butadiene in China

Richard B Hayes, Liqiang Xi, William E Bechtold, Nataniel Rothman, Ming Yao, Rogene Henderson, Luoping Zhang, Martyn T Smith, Dongpu Zhang, Joseph Wiemels, Mustafa Dosemeci, Songnian Yin, J.Patrick O'

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 552 KB

english, 1996

11

Mutagenicity and mutational spectra of 1,3-butadiene in the bone marrow of B6C3F1 lacI transgenic mice

Leslie Recio, Susan Sisk, Kathy Meyer, Linda Pluta, James A. Bond

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 513 KB

english, 1996

12

Biological monitoring of butadiene exposure by measurement of haemoglobin adducts

Kevan A. Richardson, Hendricus J.J.J. Megens, James D. Webb, Nico J. van Sittert

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 453 KB

english, 1996

13

Male-mediated F1 effects in mice exposed to 1,3-butadiene

Diana Anderson, Anne J. Edwards, M.H. Brinkworth, J.A. Hughes

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 648 KB

english, 1996

14

Species difference in the ovarian toxicity of 1,3-butadiene epoxides in B6C3F1 mice and Sprague-Dawley rats

Julie K. Doerr, Ellen A. Hollis, I.Glenn Sipes

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 777 KB

english, 1996

15

Review of reproductive and developmental toxicity of 1,3-butadiene

Mildred S. Christian

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 652 KB

english, 1996

16

Butadiene epidemiology: a summary of results and outstanding issues

John F. Acquavella

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 844 KB

english, 1996

17

Mortality study of workers employed in 1,3-butadiene production units identified from a large chemical workers cohort

Elizabeth M. Ward, John M. Fajen, Avima M. Ruder, Robert A. Rinsky, William E. Halperin, Cindy A. Fessler-Flesch

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 1.09 MB

english, 1996

18

Mortality update of butadiene production workers

Barbara J. Divine, Christine M. Hartman

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 1.11 MB

english, 1996

19

Future research needs for non-cancer and cancer effects among populations exposed to 1,3-butadiene

Aparna M. Koppikar

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 708 KB

english, 1996

20

Conducting a state-of-the-art risk assessment of 1,3-butadiene

Dennis J. Paustenbach

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 251 KB

english, 1996

21

Risk assessment of butadiene for the Existing Substances Regulation (ESR) in the European Union

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 473 KB

english, 1996

22

Using PBPK modeling and comprehensive realism methodology for the quantitative cancer risk assessment of butadiene

Robert L. Sielken Jr., Richard H. Reitz, Scan M. Hays

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 594 KB

english, 1996

23

Inhalation toxicity and carcinogenicity of isoprene in rats and mice: comparisons with 1,3-butadiene

Ronald L. Melnick, Robert C. Sills, Joseph H. Roycroft, Billy J. Chou, Harvey A. Ragan, Rodney A. Miller

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 545 KB

english, 1996

24

Chronic inhalation oncogenicity study of isoprene in B6C3F1 mice

Michael E. Placke, Larry Griffis, Michael Bird, James Bus, Ronald L. Persing, L. Anthony Cox Jr.

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 974 KB

english, 1996

25

Isoprene cancer risk and the time pattern of dose administration

Louis Anthony Cox Jr., Michael G. Bird, Larry Griffis

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 928 KB

english, 1996

26

Metabolism of isoprene in vivo

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 413 KB

english, 1996

27

Studies on the molecular toxicology of buta-1,3-diene and isoprene epoxides

Christine Bleasdale, Rowena D. Small, William P. Watson, Joanne Wilson, Bernard T. Golding

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 255 KB

english, 1996

28

Differential reactivities of the mono- and di-epoxide of 1,3-butadiene

Hermann M. Bolt, Michaela Capellmann, Brigitte Jelitto, Ulrike Hindermeier, Leonid I. Kirkovsky

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 235 KB

english, 1996

29

Hepatic and pulmonary glutathione conjugation of 1,2:3,4-diepoxybutane in human, rat, and mouse in vitro

Pieter J. Boogaard, Susan C.-J. Sumner, Max J. Turner, James A. Bond

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 255 KB

english, 1996

30

Metabolism of 1,3-butadiene: inhalation pharmacokinetics and tissue dosimetry of butadiene epoxides in rats and mice

Matthew W. Himmelstein, Max J. Turner, Bahman Asgharian, James A. Bond

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 317 KB

english, 1996

31

Physiologically based pharmacokinetic modeling of blood and tissue epoxide measurements for butadiene

Lisa M. Sweeney, Matthew W. Himmelstein, Paul M. Schlosser, Michele A. Medinsky

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 330 KB

english, 1996

32

Biological formation of the 1,3-butadiene DNA adducts 7-N-(2-hydroxy-3-buten-1-yl)guanine, 7-N-(1-hydroxy-3-buten-2-yl)guanine and 7-N-(2,3,4-trihydroxy-butyl)guanine

Hermann M. Bolt, Brigitte Jelitto

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 222 KB

english, 1996

33

Liquid chromatography/electrospray ionization tandem mass spectroscopy (LC/ESI MS/MS) analysis of 1,2-epoxybutene adducts of purine deoxynucleosides

Sara J. Kambouris, Ajai K. Chaudhary, Ian A. Blair

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 364 KB

english, 1996

34

Cytogenetic effects of butadiene metabolites in rat and mouse splenocytes following in vitro exposures

Andrew D. Kligerman, Carolyn L. Doerr, Velva S. Milholland, Alan H. Tennant

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 409 KB

english, 1996

35

32P-postlabeling of 1,3-butadiene and 4-vinyl-1-cyclohexene metabolite-DNA adducts: in vitro and in vivo applications

Nathalie Mabon, Kurt Randerath

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 277 KB

english, 1996

36

Improvement in human health risk assessment utilizing site-and chemical-specific information: a case study

J. Del Pup, J. Kmiecik, S. Smith, F. Reitman

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 343 KB

english, 1996

37

Butadiene and isoprene: future studies and implications

Hermann M. Bolt

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 452 KB

english, 1996

38

Editorial Board

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 89 KB

english, 1996

39

Foreword

Eckhard Löser, William F. Tordoir

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 67 KB

english, 1996

40

Author index

Journal:

Année:

1996

Fichier:

PDF, 109 KB

1996

41

Subject index

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 482 KB

english, 1996

42

Volume contents

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 286 KB

english, 1996

43

International symposium on the evaluation of health risks of butadiene and isoprene: general introduction

Michael G. Bird

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 208 KB

english, 1996

44

Noncancer endpoints associated with butadiene exposure: biomarkers, genotoxicity and reproductive toxicity

Richard J. Albertini, George Becking

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 321 KB

english, 1996

45

Murine thymic lymphoma is associated with a species-specific hematopoietic progenitor cell subpopulation

Richard D. Irons, Dorothy B. Colagiovanni, Wayne S. Stillman

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 889 KB

english, 1996

46

Macromolecular adducts of butadiene

Natalia Yu. Tretyakova, Yu-pang Lin, Patricia B. Upton, Ramiah Sangaiah, James A. Swenberg

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 632 KB

english, 1996

47

Assessment of exposure to butadiene in the process industry

M. Sorsa, S. Osterman-Golkar, K. Peltonen, S.T. Saarikoski, R. Šram

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 621 KB

english, 1996

48

Iroduction to epidemiology session papers

Sally R. Cowles

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 159 KB

english, 1996

49

A follow-up study of synthetic rubber workers

Elizabeth Delzell, Nalini Sathiakumar, Mary Hovinga, Maurizio Macaluso, Jim Julian, Rodney Larson, Philip Cole, David C.F. Muir

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 767 KB

english, 1996

50

Leukemia and cumulative exposure to butadiene, styrene and benzene among workers in the synthetic rubber industry

Maurizio Macaluso, Rodney Larson, Elizabeth Delzell, Nalini Sathiakumar, Mary Hovinga, Jim Julian, David Muir, Philip Cole

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 1.14 MB

english, 1996

51

Review of risk assessments on 1,3-butadiene (1985–1991)

Stuart Z. Cagen, Ross L.M. MacDonald, Gary Van Gelder

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 524 KB

english, 1996

52

Risk assessment of butadiene in ambient air; the approach used in the UK

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 377 KB

english, 1996

53

Isoprene toxicology: introduction and overview

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 135 KB

english, 1996

54

Isoprene: background and issues

Rob D.F.M. Taalman

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 482 KB

english, 1996

55

Toxicokinetics of isoprene in rodents and humans

J.G. Filser, Gy.A. Csanády, B. Denk, M. Hartmann, A. Kaufmann, W. Kessler, P.E. Kreuzer, C. Pütz, J.H. Shen, P. Stei

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 914 KB

english, 1996

56

A physiological toxicokinetic model for 1,3-butadiene in rodents and man: blood concentrations of 1,3-butadiene, its metabolically formed epoxides, and of haemoglobin adducts — relevance of glutathione depletion

Gy.A. Csanády, P.E. Kreuzer, C. Baur, J.G. Filser

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 545 KB

english, 1996

57

Pharmacokinetic model describing the disposition of butadiene and styrene in mice

Teresa L. Leavens, James A. Bond

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 334 KB

english, 1996

58

1,3-Butadiene metabolism by lung airways isolated from mice and rats

M.J. Seaton, C.G. Plopper, J.A. Bond

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 296 KB

english, 1996

59

Gender and species differences in the metabolism of 1,3-butadiene to butadiene monoepoxide and butadiene diepoxide in rodents following low-level inhalation exposures

Janice R. Thornton-Manning, Alan R. Dahl, William E. Bechtold, Rogene F. Henderson

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 290 KB

english, 1996

60

Butadiene inhalation accelerates arteriosclerotic plaque development in cockerels

Arthur Penn, Carroll A. Snyder

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 344 KB

english, 1996