Volume 109; Issue 2

Main
Proceedings of the National Academy of Sciences
Volume 109; Issue 2

Proceedings of the National Academy of Sciences

Volume 109; Issue 2

1

Regulation of oxidative DNA damage repair by DNA polymerase and MutYH by cross-talk of phosphorylation and ubiquitination

Markkanen, E., van Loon, B., Ferrari, E., Parsons, J. L., Dianov, G. L., Hubscher, U.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.51 MB

english, 2012

2

Legume pectate lyase required for root infection by rhizobia

Xie, F., Murray, J. D., Kim, J., Heckmann, A. B., Edwards, A., Oldroyd, G. E. D., Downie, J. A.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 997 KB

english, 2012

3

Metagenomic systems biology of the human gut microbiome reveals topological shifts associated with obesity and inflammatory bowel disease

Greenblum, S., Turnbaugh, P. J., Borenstein, E.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 3.38 MB

english, 2012

4

High-resolution dose-response screening using droplet-based microfluidics

Miller, O. J., Harrak, A. E., Mangeat, T., Baret, J.-C., Frenz, L., Debs, B. E., Mayot, E., Samuels, M. L., Rooney, E. K., Dieu, P., Galvan, M., Link, D. R., Griffiths, A. D.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2012

5

Evolutionary constraints on visual cortex architecture from the dynamics of hallucinations

Butler, T. C., Benayoun, M., Wallace, E., van Drongelen, W., Goldenfeld, N., Cowan, J.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 722 KB

english, 2012

6

Single-cell proteomic chip for profiling intracellular signaling pathways in single tumor cells

Shi, Q., Qin, L., Wei, W., Geng, F., Fan, R., Shik Shin, Y., Guo, D., Hood, L., Mischel, P. S., Heath, J. R.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.65 MB

english, 2012

7

Modularity of a carbon-fixing protein organelle

Bonacci, W., Teng, P. K., Afonso, B., Niederholtmeyer, H., Grob, P., Silver, P. A., Savage, D. F.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2012

8

An antinociceptive role for substance P in acid-induced chronic muscle pain

Lin, C.-C. J., Chen, W.-N., Chen, C.-J., Lin, Y.-W., Zimmer, A., Chen, C.-C.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2012

9

The nuclear receptor REV-ERB mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines

Gibbs, J. E., Blaikley, J., Beesley, S., Matthews, L., Simpson, K. D., Boyce, S. H., Farrow, S. N., Else, K. J., Singh, D., Ray, D. W., Loudon, A. S. I.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 582 KB

english, 2012

10

Gene order and chromosome dynamics coordinate spatiotemporal gene expression during the bacterial growth cycle

Sobetzko, P., Travers, A., Muskhelishvili, G.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.78 MB

english, 2012

11

Unexpectedly high mortality in Pacific herring embryos exposed to the 2007 Cosco Busan oil spill in San Francisco Bay

Incardona, J. P., Vines, C. A., Anulacion, B. F., Baldwin, D. H., Day, H. L., French, B. L., Labenia, J. S., Linbo, T. L., Myers, M. S., Olson, O. P., Sloan, C. A., Sol, S., Griffin, F. J., Menard, K.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.00 MB

english, 2012

12

Rate of meristem maturation determines inflorescence architecture in tomato

Park, S. J., Jiang, K., Schatz, M. C., Lippman, Z. B.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2012

13

Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin

Liu, J., Xu, Y., Stoleru, D., Salic, A.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2012

14

Candida albicans Dicer (CaDcr1) is required for efficient ribosomal and spliceosomal RNA maturation

Bernstein, D. A., Vyas, V. K., Weinberg, D. E., Drinnenberg, I. A., Bartel, D. P., Fink, G. R.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2012

15

Formation of buckminsterfullerene (C60) in interstellar space

Berne, O., Tielens, A. G. G. M.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 780 KB

english, 2012

16

Vertebrate-like regeneration in the invertebrate chordate amphioxus

Somorjai, I. M. L., Somorjai, R. L., Garcia-Fernandez, J., Escriva, H.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2012

17

Structural basis for gating charge movement in the voltage sensor of a sodium channel

Yarov-Yarovoy, V., DeCaen, P. G., Westenbroek, R. E., Pan, C.-Y., Scheuer, T., Baker, D., Catterall, W. A.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 2.46 MB

english, 2012

18

Non-coalescence of oppositely charged droplets in pH-sensitive emulsions

Liu, T., Seiffert, S., Thiele, J., Abate, A. R., Weitz, D. A., Richtering, W.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2012

19

Signal transducer and activator of transcription 3 (STAT3) and survivin induction by varicella-zoster virus promote replication and skin pathogenesis

Sen, N., Che, X., Rajamani, J., Zerboni, L., Sung, P., Ptacek, J., Arvin, A. M.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 891 KB

english, 2012

20

Genome and physiology of a model Epsilonproteobacterium responsible for sulfide detoxification in marine oxygen depletion zones

Grote, J., Schott, T., Bruckner, C. G., Glockner, F. O., Jost, G., Teeling, H., Labrenz, M., Jurgens, K.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 870 KB

english, 2012

21

Database independent proteomics analysis of the ostrich and human proteome

Altelaar, A. F. M., Navarro, D., Boekhorst, J., van Breukelen, B., Snel, B., Mohammed, S., Heck, A. J. R.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 802 KB

english, 2012

22

Tumor suppression by cell competition through regulation of the Hippo pathway

Chen, C.-L., Schroeder, M. C., Kango-Singh, M., Tao, C., Halder, G.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.69 MB

english, 2012

23

DNA methyltransferase 3a limits the expression of interleukin-13 in T helper 2 cells and allergic airway inflammation

Yu, Q., Zhou, B., Zhang, Y., Nguyen, E. T., Du, J., Glosson, N. L., Kaplan, M. H.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 854 KB

english, 2012

24

Wip1 promotes RUNX2-dependent apoptosis in p53-negative tumors and protects normal tissues during treatment with anticancer agents

Goloudina, A. R., Tanoue, K., Hammann, A., Fourmaux, E., Le Guezennec, X., Bulavin, D. V., Mazur, S. J., Appella, E., Garrido, C., Demidov, O. N.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.00 MB

english, 2012

25

Human cytomegalovirus activation of ERK and myeloid cell leukemia-1 protein correlates with survival of latently infected cells

Reeves, M. B., Breidenstein, A., Compton, T.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 469 KB

english, 2012

26

Secreted Wingless-interacting molecule (Swim) promotes long-range signaling by maintaining Wingless solubility

Mulligan, K. A., Fuerer, C., Ching, W., Fish, M., Willert, K., Nusse, R.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.60 MB

english, 2012

27

Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase

Jacob, C. O., Eisenstein, M., Dinauer, M. C., Ming, W., Liu, Q., John, S., Quismorio, F. P., Reiff, A., Myones, B. L., Kaufman, K. M., McCurdy, D., Harley, J. B., Silverman, E., Kimberly, R. P., Vyse,

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2012

28

Sperm-borne microRNA-34c is required for the first cleavage division in mouse

Liu, W.-M., Pang, R. T. K., Chiu, P. C. N., Wong, B. P. C., Lao, K., Lee, K.-F., Yeung, W. S. B.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 581 KB

english, 2012

29

Specific neural substrate linking respiration to locomotion

Gariepy, J.-F., Missaghi, K., Chevallier, S., Chartre, S., Robert, M., Auclair, F., Lund, J. P., Dubuc, R.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.75 MB

english, 2012

30

More with less Xist

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 509 KB

english, 2012

31

Culture does account for variation in game behavior

Henrich, J., Boyd, R., McElreath, R., Gurven, M., Richerson, P. J., Ensminger, J., Alvard, M., Barr, A., Barrett, C., Bolyanatz, A., Camerer, C. F., Cardenas, J.-C., Fehr, E., Gintis, H. M., Gil-White

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 446 KB

english, 2012

32

Cheating monkeys undermine group strength in enemy territory

Crofoot, M. C., Gilby, I. C.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 556 KB

english, 2012

33

Growth, metabolic partitioning, and the size of microorganisms

Kempes, C. P., Dutkiewicz, S., Follows, M. J.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 545 KB

english, 2012

34

Gastrin-releasing peptide receptor (GRPR) mediates chemotaxis in neutrophils

Czepielewski, R. S., Porto, B. N., Rizzo, L. B., Roesler, R., Abujamra, A. L., Pinto, L. G., Schwartsmann, G., Cunha, F. d. Q., Bonorino, C.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 560 KB

english, 2012

35

Correction for Chen et al., Tomosyn-dependent regulation of synaptic transmission is required for a late phase of associative odor memory,

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Fichier:

PDF, 32 KB

2012

36

Multiple independent introductions of Plasmodium falciparum in South America

Yalcindag, E., Elguero, E., Arnathau, C., Durand, P., Akiana, J., Anderson, T. J., Aubouy, A., Balloux, F., Besnard, P., Bogreau, H., Carnevale, P., D'Alessandro, U., Fontenille, D., Gamboa, D., Jomba

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Fichier:

PDF, 645 KB

2012

37

Role for the molecular chaperones Zuo1 and Ssz1 in quorum sensing via activation of the transcription factor Pdr1

Prunuske, A. J., Waltner, J. K., Kuhn, P., Gu, B., Craig, E. A.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 820 KB

english, 2012

38

AMP-activated protein kinase is physiologically regulated by inositol polyphosphate multikinase

Bang, S., Kim, S., Dailey, M. J., Chen, Y., Moran, T. H., Snyder, S. H., Kim, S. F.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 829 KB

english, 2012

39

Targeting protein-trafficking pathways alters melanoma treatment sensitivity

Huang, Z.-m., Chinen, M., Chang, P. J., Xie, T., Zhong, L., Demetriou, S., Patel, M. P., Scherzer, R., Sviderskaya, E. V., Bennett, D. C., Millhauser, G. L., Oh, D. H., Cleaver, J. E., Wei, M. L.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 594 KB

english, 2012

40

In This Issue

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 9.53 MB

english, 2012

41

Extensive genetic diversity and substructuring among zebrafish strains revealed through copy number variant analysis

Brown, K. H., Dobrinski, K. P., Lee, A. S., Gokcumen, O., Mills, R. E., Shi, X., Chong, W. W. S., Chen, J. Y. H., Yoo, P., David, S., Peterson, S. M., Raj, T., Choy, K. W., Stranger, B. E., Williamson

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 642 KB

english, 2012

42

Type 1 ryanodine receptor knock-in mutation causing central core disease of skeletal muscle also displays a neuronal phenotype

De Crescenzo, V., Fogarty, K. E., Lefkowitz, J. J., Bellve, K. D., Zvaritch, E., MacLennan, D. H., Walsh, J. V.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 595 KB

english, 2012

43

Revealing conformational substates of lipidated N-Ras protein by pressure modulation

Kapoor, S., Triola, G., Vetter, I. R., Erlkamp, M., Waldmann, H., Winter, R.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2012

44

The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations

Yan, K. S., Chia, L. A., Li, X., Ootani, A., Su, J., Lee, J. Y., Su, N., Luo, Y., Heilshorn, S. C., Amieva, M. R., Sangiorgi, E., Capecchi, M. R., Kuo, C. J.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2012

45

Schooling in adolescence raises IQ scores

Brinch, C. N., Galloway, T. A.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 540 KB

english, 2012

46

Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma

Xie, Q., Bradley, R., Kang, L., Koeman, J., Ascierto, M. L., Worschech, A., De Giorgi, V., Wang, E., Kefene, L., Su, Y., Essenburg, C., Kaufman, D. W., DeKoning, T., Enter, M. A., O'Rourke, T. J., Mar

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 704 KB

english, 2012

47

QnAs with John A. Rogers

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 466 KB

english, 2012

48

Disordered form of the scaffold protein IscU is the substrate for iron-sulfur cluster assembly on cysteine desulfurase

Kim, J. H., Tonelli, M., Markley, J. L.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 947 KB

english, 2012

49

Bayesian analysis of the astrobiological implications of life's early emergence on Earth

Spiegel, D. S., Turner, E. L.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 441 KB

english, 2012

50

Alpha-1-antitrypsin monotherapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation

Tawara, I., Sun, Y., Lewis, E. C., Toubai, T., Evers, R., Nieves, E., Azam, T., Dinarello, C. A., Reddy, P.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 820 KB

english, 2012

51

A single conformational transglutaminase 2 epitope contributed by three domains is critical for celiac antibody binding and effects

Simon-Vecsei, Z., Kiraly, R., Bagossi, P., Toth, B., Dahlbom, I., Caja, S., Csosz, E., Lindfors, K., Sblattero, D., Nemes, E., Maki, M., Fesus, L., Korponay-Szabo, I. R.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 942 KB

english, 2012

52

Activation of growth hormone releasing hormone (GHRH) receptor stimulates cardiac reverse remodeling after myocardial infarction (MI)

Kanashiro-Takeuchi, R. M., Takeuchi, L. M., Rick, F. G., Dulce, R., Treuer, A. V., Florea, V., Rodrigues, C. O., Paulino, E. C., Hatzistergos, K. E., Selem, S. M., Gonzalez, D. R., Block, N. L., Schal

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 566 KB

english, 2012

53

Nonplanar peptide bonds in proteins are common and conserved but not biased toward active sites

Berkholz, D. S., Driggers, C. M., Shapovalov, M. V., Dunbrack, R. L., Karplus, P. A.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 3.06 MB

english, 2012

54

Safe storage and effective monitoring of CO2 in depleted gas fields

Jenkins, C. R., Cook, P. J., Ennis-King, J., Undershultz, J., Boreham, C., Dance, T., de Caritat, P., Etheridge, D. M., Freifeld, B. M., Hortle, A., Kirste, D., Paterson, L., Pevzner, R., Schacht, U.,

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 2.15 MB

english, 2012

55

Understanding fast macroscale fracture from microcrack post mortem patterns

Guerra, C., Scheibert, J., Bonamy, D., Dalmas, D.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.64 MB

english, 2012

56

D-Amino acid oxidase controls motoneuron degeneration through D-serine

Sasabe, J., Miyoshi, Y., Suzuki, M., Mita, M., Konno, R., Matsuoka, M., Hamase, K., Aiso, S.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2012

57

Evidence for formation of DNA repair centers and dose-response nonlinearity in human cells

Neumaier, T., Swenson, J., Pham, C., Polyzos, A., Lo, A. T., Yang, P., Dyball, J., Asaithamby, A., Chen, D. J., Bissell, M. J., Thalhammer, S., Costes, S. V.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2012

58

Reply to Henrich et al.: Behavioral variation needs to be quantified at multiple levels

Lamba, S., Mace, R.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 430 KB

english, 2012

59

Double-strand break motions shift radiation risk notions?

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 598 KB

english, 2012

60

Thrombocytopenia and erythrocytosis in mice with a mutation in the gene encoding the hemoglobin minor chain

Kauppi, M., Hilton, A. A., Metcalf, D., Ng, A. P., Hyland, C. D., Collinge, J. E., Kile, B. T., Hilton, D. J., Alexander, W. S.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 555 KB

english, 2012

61

Correction for Ribas et al., Myeloid-specific estrogen receptor deficiency impairs metabolic homeostasis and accelerates atherosclerotic lesion development

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 38 KB

english, 2012

62

A role for neuronal cAMP responsive-element binding (CREB)-1 in brain responses to calorie restriction

Fusco, S., Ripoli, C., Podda, M. V., Ranieri, S. C., Leone, L., Toietta, G., McBurney, M. W., Schutz, G., Riccio, A., Grassi, C., Galeotti, T., Pani, G.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 614 KB

english, 2012

63

Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells

Giraud, M., Yoshida, H., Abramson, J., Rahl, P. B., Young, R. A., Mathis, D., Benoist, C.

Journal:

Proceedings of the National Academy of Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 5.53 MB

english, 2012