Volume 101; Issue 29

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Proceedings of the National Academy of Sciences
Volume 101; Issue 29

Proceedings of the National Academy of Sciences

Volume 101; Issue 29

1

MS analysis of single-nucleotide differences in circulating nucleic acids: Application to noninvasive prenatal diagnosis

Ding, C., Chiu, R. W. K., Lau, T. K., Leung, T. N., Chan, L. C., Chan, A. Y. Y., Charoenkwan, P., Ng, I. S. L., Law, H.-y., Ma, E. S. K., Xu, X., Wanapirak, C., Sanguansermsri, T., Liao, C., Ai, M. A.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 321 KB

english, 2004

2

O-GlcNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer's disease

Liu, F., Iqbal, K., Grundke-Iqbal, I., Hart, G. W., Gong, C.-X.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 515 KB

english, 2004

3

Ethanol toxicity in pancreatic acinar cells: Mediation by nonoxidative fatty acid metabolites

Criddle, D. N., Raraty, M. G. T., Neoptolemos, J. P., Tepikin, A. V., Petersen, O. H., Sutton, R.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 540 KB

english, 2004

4

Expanded dynamic range of fluorescent indicators for Ca2+ by circularly permuted yellow fluorescent proteins

Nagai, T., Yamada, S., Tominaga, T., Ichikawa, M., Miyawaki, A.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 676 KB

english, 2004

5

Directed evolution of ligand dependence: Small-molecule-activated protein splicing

Buskirk, A. R., Ong, Y.-C., Gartner, Z. J., Liu, D. R.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 515 KB

english, 2004

6

Charge equilibration between two distinct sites in double helical DNA

Delaney, S., Yoo, J., Stemp, E. D. A., Barton, J. K.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 430 KB

english, 2004

7

A rare-cell detector for cancer

Krivacic, R. T., Ladanyi, A., Curry, D. N., Hsieh, H. B., Kuhn, P., Bergsrud, D. E., Kepros, J. F., Barbera, T., Ho, M. Y., Chen, L. B., Lerner, R. A., Bruce, R. H.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 245 KB

english, 2004

8

Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E

Michelsen, K. S., Wong, M. H., Shah, P. K., Zhang, W., Yano, J., Doherty, T. M., Akira, S., Rajavashisth, T. B., Arditi, M.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 503 KB

english, 2004

9

Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity

Yao, D., Gu, Z., Nakamura, T., Shi, Z.-Q., Ma, Y., Gaston, B., Palmer, L. A., Rockenstein, E. M., Zhang, Z., Masliah, E., Uehara, T., Lipton, S. A.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 469 KB

english, 2004

10

PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells

Latchman, Y. E., Liang, S. C., Wu, Y., Chernova, T., Sobel, R. A., Klemm, M., Kuchroo, V. K., Freeman, G. J., Sharpe, A. H.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 433 KB

english, 2004

11

Requirement of matrix metalloproteinase-9 for the transformation of human mammary epithelial cells by Stat3-C

Dechow, T. N., Pedranzini, L., Leitch, A., Leslie, K., Gerald, W. L., Linkov, I., Bromberg, J. F.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 632 KB

english, 2004

12

Direct measurement of proton release by cytochrome c oxidase in solution during the F->O transition

Zaslavsky, D., Sadoski, R. C., Rajagukguk, S., Geren, L., Millett, F., Durham, B., Gennis, R. B.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 264 KB

english, 2004

13

The human and African green monkey TRIM5 genes encode Ref1 and Lv1 retroviral restriction factor activities

Keckesova, Z., Ylinen, L. M. J., Towers, G. J.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 478 KB

english, 2004

14

Mouse dyskerin mutations affect accumulation of telomerase RNA and small nucleolar RNA, telomerase activity, and ribosomal RNA processing

Mochizuki, Y., He, J., Kulkarni, S., Bessler, M., Mason, P. J.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 397 KB

english, 2004

15

Absence of a reductase, NCB5OR, causes insulin-deficient diabetes

Xie, J., Zhu, H., Larade, K., Ladoux, A., Seguritan, A., Chu, M., Ito, S., Bronson, R. T., Leiter, E. H., Zhang, C.-Y., Rosen, E. D., Bunn, H. F.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 554 KB

english, 2004

16

MotifPrototyper: A Bayesian profile model for motif families

Xing, E. P., Karp, R. M.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 465 KB

english, 2004

17

From The Cover: Development of a cancer DNA phenotype prior to tumor formation

Malins, D. C., Anderson, K. M., Gilman, N. K., Green, V. M., Barker, E. A., Hellstrom, K. E.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 418 KB

english, 2004

18

Somatolactin selectively regulates proliferation and morphogenesis of neural-crest derived pigment cells in medaka

Fukamachi, S., Sugimoto, M., Mitani, H., Shima, A.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2004

19

Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells

Menendez, J. A., Vellon, L., Mehmi, I., Oza, B. P., Ropero, S., Colomer, R., Lupu, R.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 689 KB

english, 2004

20

The Arabidopsis AtRAD51 gene is dispensable for vegetative development but required for meiosis

Li, W., Chen, C., Markmann-Mulisch, U., Timofejeva, L., Schmelzer, E., Ma, H., Reiss, B.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 580 KB

english, 2004

21

The effects of host contact network structure on pathogen diversity and strain structure

Buckee, C. OF., Koelle, K., Mustard, M. J., Gupta, S.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 802 KB

english, 2004

22

Primate jumping genes elucidate strepsirrhine phylogeny

Roos, C., Schmitz, J., Zischler, H.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 746 KB

english, 2004

23

Chaotic microlasers based on dynamical localization

Podolskiy, V. A., Narimanov, E., Fang, W., Cao, H.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 327 KB

english, 2004

24

A methionine aminopeptidase-2 inhibitor, PPI-2458, for the treatment of rheumatoid arthritis

Bernier, S. G., Lazarus, D. D., Clark, E., Doyle, B., Labenski, M. T., Thompson, C. D., Westlin, W. F., Hannig, G.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 366 KB

english, 2004

25

Unique modifications with phosphocholine and phosphoethanolamine define alternate antigenic forms of Neisseria gonorrhoeae type IV pili

Hegge, F. T., Hitchen, P. G., Aas, F. E., Kristiansen, H., Lovold, C., Egge-Jacobsen, W., Panico, M., Leong, W. Y., Bull, V., Virji, M., Morris, H. R., Dell, A., Koomey, M.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 433 KB

english, 2004

26

The Treacher Collins syndrome (TCOF1) gene product is involved in ribosomal DNA gene transcription by interacting with upstream binding factor

Valdez, B. C., Henning, D., So, R. B., Dixon, J., Dixon, M. J.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 506 KB

english, 2004

27

The Spn4 gene of Drosophila encodes a potent furin-directed secretory pathway serpin

Richer, M. J., Keays, C. A., Waterhouse, J., Minhas, J., Hashimoto, C., Jean, F.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 467 KB

english, 2004

28

Bipolar orientation of chromosomes in Saccharomyces cerevisiae is monitored by Mad1 and Mad2, but not by Mad3

Lee, M. S., Spencer, F. A.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 576 KB

english, 2004

29

Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad integrated antibody and CD4+ and CD8+ T cell responses in humans

Davis, I. D., Chen, W., Jackson, H., Parente, P., Shackleton, M., Hopkins, W., Chen, Q., Dimopoulos, N., Luke, T., Murphy, R., Scott, A. M., Maraskovsky, E., McArthur, G., MacGregor, D., Sturrock, S.,

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 655 KB

english, 2004

30

Trim5 protein restricts both HIV-1 and murine leukemia virus

Yap, M. W., Nisole, S., Lynch, C., Stoye, J. P.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 543 KB

english, 2004

31

Pattern of polymorphism after strong artificial selection in a domestication event

Innan, H., Kim, Y.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 555 KB

english, 2004

32

Functional disassociation of the central and peripheral fatty acid amide signaling systems

Cravatt, B. F., Saghatelian, A., Hawkins, E. G., Clement, A. B., Bracey, M. H., Lichtman, A. H.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 534 KB

english, 2004

33

RENKCTD11 is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma

Di Marcotullio, L., Ferretti, E., De Smaele, E., Argenti, B., Mincione, C., Zazzeroni, F., Gallo, R., Masuelli, L., Napolitano, M., Maroder, M., Modesti, A., Giangaspero, F., Screpanti, I., Alesse, E.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 670 KB

english, 2004

34

Responsible authorship of papers in PNAS

Cozzarelli, N. R.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 61 KB

english, 2004

35

Drs2p-coupled aminophospholipid translocase activity in yeast Golgi membranes and relationship to in vivo function

Natarajan, P., Wang, J., Hua, Z., Graham, T. R.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 470 KB

english, 2004

36

Evolutionary dynamics of tumor suppressor gene inactivation

Nowak, M. A., Michor, F., Komarova, N. L., Iwasa, Y.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 250 KB

english, 2004

37

Emx2 homeodomain transcription factor interacts with eukaryotic translation initiation factor 4E (eIF4E) in the axons of olfactory sensory neurons

Nedelec, S., Foucher, I., Brunet, I., Bouillot, C., Prochiantz, A., Trembleau, A.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 598 KB

english, 2004

38

Tree-structured supervised learning and the genetics of hypertension

Huang, J., Lin, A., Narasimhan, B., Quertermous, T., Hsiung, C. A., Ho, L.-T., Grove, J. S., Olivier, M., Ranade, K., Risch, N. J., Olshen, R. A.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 295 KB

english, 2004

39

NFAT is a nerve activity sensor in skeletal muscle and controls activity-dependent myosin switching

McCullagh, K. J. A., Calabria, E., Pallafacchina, G., Ciciliot, S., Serrano, A. L., Argentini, C., Kalhovde, J. M., Lomo, T., Schiaffino, S.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 713 KB

english, 2004

40

Abnormal sperm in mice with targeted deletion of the act (activator of cAMP-responsive element modulator in testis) gene

Kotaja, N., De Cesare, D., Macho, B., Monaco, L., Brancorsini, S., Goossens, E., Tournaye, H., Gansmuller, A., Sassone-Corsi, P.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 556 KB

english, 2004

41

NFAT5/TonEBP mutant mice define osmotic stress as a critical feature of the lymphoid microenvironment

Go, W. Y., Liu, X., Roti, M. A., Liu, F., Ho, S. N.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 478 KB

english, 2004

42

Essential role of brain-derived neurotrophic factor in adult hippocampal function

Monteggia, L. M., Barrot, M., Powell, C. M., Berton, O., Galanis, V., Gemelli, T., Meuth, S., Nagy, A., Greene, R. W., Nestler, E. J.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 657 KB

english, 2004

43

The mitochondrial genome of Paraspadella gotoi is highly reduced and reveals that chaetognaths are a sister group to protostomes

Helfenbein, K. G., Fourcade, H. M., Vanjani, R. G., Boore, J. L.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 439 KB

english, 2004

44

Magnetic circular dichroism of peralkylated tetrasilane conformers

Fogarty, H. A., Imhof, R., Michl, J.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 318 KB

english, 2004

45

The voltage-gated Na+ channel NaVBP has a role in motility, chemotaxis, and pH homeostasis of an alkaliphilic Bacillus

Ito, M., Xu, H., Guffanti, A. A., Wei, Y., Zvi, L., Clapham, D. E., Krulwich, T. A.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 1.81 MB

english, 2004

46

An amyloid-forming segment of 2-microglobulin suggests a molecular model for the fibril

Ivanova, M. I., Sawaya, M. R., Gingery, M., Attinger, A., Eisenberg, D.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 613 KB

english, 2004

47

Mycobacterial phosphatidylinositol mannoside is a natural antigen for CD1d-restricted T cells

Fischer, K., Scotet, E., Niemeyer, M., Koebernick, H., Zerrahn, J., Maillet, S., Hurwitz, R., Kursar, M., Bonneville, M., Kaufmann, S. H. E., Schaible, U. E.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 575 KB

english, 2004

48

Vasorin, a transforming growth factor -binding protein expressed in vascular smooth muscle cells, modulates the arterial response to injury in vivo

Ikeda, Y., Imai, Y., Kumagai, H., Nosaka, T., Morikawa, Y., Hisaoka, T., Manabe, I., Maemura, K., Nakaoka, T., Imamura, T., Miyazono, K., Komuro, I., Nagai, R., Kitamura, T.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 722 KB

english, 2004

49

Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5

Hatziioannou, T., Perez-Caballero, D., Yang, A., Cowan, S., Bieniasz, P. D.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 598 KB

english, 2004

50

Structure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant reverse transcriptases resistant to other nonnucleoside inhibitors

Pata, J. D., Stirtan, W. G., Goldstein, S. W., Steitz, T. A.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 601 KB

english, 2004

51

Binding of platelet glycoprotein Ib to von Willebrand factor domain A1 stimulates the cleavage of the adjacent domain A2 by ADAMTS13

Nishio, K., Anderson, P. J., Zheng, X. L., Sadler, J. E.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 431 KB

english, 2004

52

In defense of the cell: TRIM5 interception of mammalian retroviruses

Lee, K., KewalRamani, V. N.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 138 KB

english, 2004

53

Target of rapamycin-mediated amino acid signaling in mosquito anautogeny

Hansen, I. A., Attardo, G. M., Park, J.-H., Peng, Q., Raikhel, A. S.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 439 KB

english, 2004

54

Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication

Coskun, P. E., Beal, M. F., Wallace, D. C.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 520 KB

english, 2004

55

Selective disruption of PPAR 2 impairs the development of adipose tissue and insulin sensitivity

Zhang, J., Fu, M., Cui, T., Xiong, C., Xu, K., Zhong, W., Xiao, Y., Floyd, D., Liang, J., Li, E., Song, Q., Chen, Y. E.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 566 KB

english, 2004

56

Loss of locus coeruleus neurons and reduced startle in parkin null mice

von Coelln, R., Thomas, B., Savitt, J. M., Lim, K. L., Sasaki, M., Hess, E. J., Dawson, V. L., Dawson, T. M.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 494 KB

english, 2004

57

An alternative agriculture system is defined by a distinct expression profile of select gene transcripts and proteins

Kumar, V., Mills, D. J., Anderson, J. D., Mattoo, A. K.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 454 KB

english, 2004

58

Snow conditions may create an invisible barrier for lynx

Stenseth, N. C., Shabbar, A., Chan, K.-S., Boutin, S., Rueness, E. K., Ehrich, D., Hurrell, J. W., Lingjaerde, O. Chr., Jakobsen, K. S.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 256 KB

english, 2004

59

Wild chimpanzee dentition and its implications for assessing life history in immature hominin fossils

Zihlman, A., Bolter, D., Boesch, C.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 228 KB

english, 2004

60

Met provides essential signals for liver regeneration

Borowiak, M., Garratt, A. N., Wustefeld, T., Strehle, M., Trautwein, C., Birchmeier, C.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 574 KB

english, 2004

61

Protozoan predation, diversifying selection, and the evolution of antigenic diversity in Salmonella

Wildschutte, H., Wolfe, D. M., Tamewitz, A., Lawrence, J. G.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 511 KB

english, 2004

62

Varicella-zoster virus infection of human neural cells in vivo

Baiker, A., Fabel, K., Cozzio, A., Zerboni, L., Fabel, K., Sommer, M., Uchida, N., He, D., Weissman, I., Arvin, A. M.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2004

63

Heterodimeric complexes of Hop2 and Mnd1 function with Dmc1 to promote meiotic homolog juxtaposition and strand assimilation

Chen, Y.-K., Leng, C.-H., Olivares, H., Lee, M.-H., Chang, Y.-C., Kung, W.-M., Ti, S.-C., Lo, Y.-H., Wang, A. H.-J., Chang, C.-S., Bishop, D. K., Hsueh, Y.-P., Wang, T.-F.

Journal:

Proceedings of the National Academy of Sciences

Année:

2004

Langue:

english

Fichier:

PDF, 438 KB

english, 2004