Volume 16; Issue 6

Main
PLoS Genetics
Volume 16; Issue 6

PLoS Genetics

Volume 16; Issue 6

1

Integrins regulate epithelial cell shape by controlling the architecture and mechanical properties of basal actomyosin networks

Santa-Cruz Mateos, Carmen, Valencia-ExpÃ³sito, Andrea, Palacios, Isabel M., MartÃn-Bermudo, MarÃa D., Huynh, Jean-RenÃ©

Journal:

Année:

2020

Fichier:

PDF, 4.27 MB

2020

2

Adaptation of codon usage to tRNA I34 modification controls translation kinetics and proteome landscape

Lyu, Xueliang, Yang, Qian, Li, Lin, Dang, Yunkun, Zhou, Zhipeng, Chen, She, Liu, Yi, Freitag, Michael

Journal:

Année:

2020

Fichier:

PDF, 9.46 MB

2020

3

Osteocalcin promotes bone mineralization but is not a hormone

Manolagas, Stavros C., Bateman, John F.

Journal:

Année:

2020

Fichier:

PDF, 459 KB

2020

4

Transcriptomic stratification of late-onset Alzheimer's cases reveals novel genetic modifiers of disease pathology

Milind, Nikhil, Preuss, Christoph, Haber, Annat, Ananda, Guruprasad, Mukherjee, Shubhabrata, John, Cai, Shapley, Sarah, Logsdon, Benjamin A., Crane, Paul K., Carter, Gregory W., Barsh, Gregory S.

Journal:

Année:

2020

Fichier:

PDF, 6.04 MB

2020

5

Genetic analysis of osteoblast activity identifies Zbtb40 as a regulator of osteoblast activity and bone mass

Doolittle, Madison L., Calabrese, Gina M., Mesner, Larry D., Godfrey, Dana A., Maynard, Robert D., Ackert-Bicknell, Cheryl L., Farber, Charles R., Cox, Gregory A.

Journal:

Année:

2020

Fichier:

PDF, 4.71 MB

2020

6

In vivoÂ modeling of metastatic human high-grade serous ovarian cancer in mice

Kim, Olga, Park, Eun Young, Klinkebiel, David L., Pack, Svetlana D., Shin, Yong-Hyun, Abdullaev, Zied, Emerson, Robert E., Coffey, Donna M., Kwon, Sun Young, Creighton, Chad J., Kwon, Sanghoon, Chang,

Journal:

Année:

2020

Fichier:

PDF, 18.91 MB

2020

7

Identification of Clec4b asÂ a novel regulator of bystander activation of auto-reactive T cells and autoimmune disease

BÃ¤ckdahl, Liselotte, Aoun, Mike, Norin, Ulrika, Holmdahl, Rikard, Roopenian, Derry C.

Journal:

Année:

2020

Fichier:

PDF, 6.20 MB

2020

8

GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation

Kothandapani, Anbarasi, Lewis, Samantha R., Noel, Jessica L., Zacharski, Abbey, Krellwitz, Kyle, Baines, Anna, Winske, Stephanie, Vezina, Chad M., Kaftanovskaya, Elena M., Agoulnik, Alexander I., Mert

Journal:

Année:

2020

Fichier:

PDF, 18.53 MB

2020

9

An Africa-wide genomic evolution of insecticide resistance in the malaria vector Anopheles funestus involves selective sweeps, copy number variations, gene conversion and transposons

Weedall, Gareth D., Riveron, Jacob M., Hearn, Jack, Irving, Helen, Kamdem, Colince, Fouet, Caroline, White, Bradley J., Wondji, Charles S., ffrench-Constant, Richard H.

Journal:

Année:

2020

Fichier:

PDF, 3.11 MB

2020

10

Super-resolution imaging of RAD51 and DMC1 in DNA repair foci reveals dynamic distribution patterns in meiotic prophase

Slotman, Johan A., Paul, Maarten W., Carofiglio, Fabrizia, de Gruiter, H. Martijn, Vergroesen, Tessa, Koornneef, Lieke, van Cappellen, Wiggert A., Houtsmuller, Adriaan B., Baarends, Willy M., Bishop,

Journal:

Année:

2020

Fichier:

PDF, 13.02 MB

2020

11

BRM-SWI/SNF chromatin remodeling complex enables functional telomeres by promoting co-expression of TRF2 and TRF1

Wu, Shu, Ge, Yuanlong, Li, Xiaocui, Yang, Yiding, Zhou, Haoxian, Lin, Kaixuan, Zhang, Zepeng, Zhao, Yong, Zhou, Jin-Qiu

Journal:

Année:

2020

Fichier:

PDF, 11.69 MB

2020

12

BK channel density is regulated by endoplasmic reticulum associated degradation and influenced by the SKN-1A/NRF1 transcription factor

Cheung, Timothy P., Choe, Jun-Yong, Richmond, Janet E., Kim, Hongkyun, Hart, Anne C.

Journal:

Année:

2020

Fichier:

PDF, 3.96 MB

2020

13

Zebrafish rbm8a and magoh mutants reveal EJC developmental functions and new 3â²UTR intron-containing NMD targets

Gangras, Pooja, Gallagher, Thomas L., Parthun, Michael A., Yi, Zhongxia, Patton, Robert D., Tietz, Kiel T., Deans, Natalie C., Bundschuh, Ralf, Amacher, Sharon L., Singh, Guramrit, MÃ¼hlemann, Oliver

Journal:

Année:

2020

Fichier:

PDF, 9.91 MB

2020

14

Evolution of Salmonella enterica serotype Typhimurium driven by anthropogenic selection and niche adaptation

Bawn, Matt, Alikhan, Nabil-Fareed, Thilliez, GaÃ«tan, Kirkwood, Mark, Wheeler, Nicole E., Petrovska, Liljana, Dallman, Timothy J., Adriaenssens, Evelien M., Hall, Neil, Kingsley, Robert A., Didelot, X

Journal:

Année:

2020

Fichier:

PDF, 3.55 MB

2020

15

MYO5B mutations in pheochromocytoma/paraganglioma promote cancer progression

TomiÄ, Tajana TeÅ¡an, Olausson, Josefin, Rehammar, Anna, Deland, Lily, Muth, Andreas, EjeskÃ¤r, Katarina, Nilsson, Staffan, Kristiansson, Erik, WassÃ©n, Ola Nilsson, Abel, Frida, Wilkerson, Matthew D

Journal:

Année:

2020

Fichier:

PDF, 13.26 MB

2020

16

The cohesin loader SCC2 contains a PHD finger that is required for meiosis in land plants

Wang, Hongkuan, Xu, Wanyue, Sun, Yujin, Lian, Qichao, Wang, Cong, Yu, Chaoyi, He, Chengpeng, Wang, Jun, Ma, Hong, Copenhaver, Gregory P., Wang, Yingxiang, Barsh, Gregory S.

Journal:

Année:

2020

Fichier:

PDF, 27.85 MB

2020

17

Regulation of olfactory-based sex behaviors in the silkworm by genes in the sex-determination cascade

Xu, Jun, Liu, Wei, Yang, Dehong, Chen, Shuqing, Chen, Kai, Liu, Zulian, Yang, Xu, Meng, Jing, Zhu, Guanheng, Dong, Shuanglin, Zhang, Yong, Zhan, Shuai, Wang, Guirong, Huang, Yongping, Copenhaver, Greg

Journal:

Année:

2020

Fichier:

PDF, 3.08 MB

2020

18

Duplication and divergence of the retrovirus restriction gene Fv1 in Mus caroli allows protection from multiple retroviruses

Yap, Melvyn W., Young, George R., Varnaite, Renata, Morand, Serge, Stoye, Jonathan P., Malik, Harmit S.

Journal:

Année:

2020

Fichier:

PDF, 3.73 MB

2020

19

Exclusive breastfeeding can attenuate body-mass-index increase among genetically susceptible children: A longitudinal study from the ALSPAC cohort

Wu, Yanyan, Lye, Stephen, Dennis, Cindy-Lee, Briollais, Laurent, Ripatti, Samuli

Journal:

Année:

2020

Fichier:

PDF, 2.00 MB

2020

20

Elevated exopolysaccharide levels in Pseudomonas aeruginosa flagellar mutants have implications for biofilm growth and chronic infections

Harrison, Joe J., Almblad, Henrik, Irie, Yasuhiko, Wolter, Daniel J., Eggleston, Heather C., Randall, Trevor E., Kitzman, Jacob O., Stackhouse, Bethany, Emerson, Julia C., Mcnamara, Sharon, Larsen, Ty

Journal:

Année:

2020

Fichier:

PDF, 10.99 MB

2020

21

Phylogenetic background and habitat drive the genetic diversification of Escherichia coli

Touchon, Marie, Perrin, Amandine, de Sousa, Jorge AndrÃ© Moura, Vangchhia, Belinda, Burn, Samantha, OâBrien, Claire L., Denamur, Erick, Gordon, David, Rocha, Eduardo PC, Didelot, Xavier

Journal:

Année:

2020

Fichier:

PDF, 4.37 MB

2020

22

Cancer-associated mutations in the iron-sulfur domain of FANCJ affect G-quadruplex metabolism

Odermatt, Diana C., Lee, Wei Ting C., Wild, Sebastian, Jozwiakowski, Stanislaw K., Rothenberg, Eli, Gari, Kerstin, Deans, Andrew

Journal:

Année:

2020

Fichier:

PDF, 4.87 MB

2020

23

yippee like 3Â (ypel3) is a novel gene required for myelinating and perineurial glia development

Blanco-SÃ¡nchez, Bernardo, ClÃ©ment, AurÃ©lie, Stednitz, Sara J., Kyle, Jennifer, Peirce, Judy L., McFadden, Marcie, Wegner, Jeremy, Phillips, Jennifer B., Macnamara, Ellen, Huang, Yan, Adams, David R

Journal:

Année:

2020

Fichier:

PDF, 22.20 MB

2020

24

Steroid hormones regulate genome-wide epigenetic programming and gene transcription in human endometrial cells with marked aberranciesÂ in endometriosis

Houshdaran, Sahar, Oke, Ashwini B., Fung, Jennifer C., Vo, Kim Chi, Nezhat, Camran, Giudice, Linda C., Bartolomei, Marisa S.

Journal:

Année:

2020

Fichier:

PDF, 2.20 MB

2020

25

NRF2 loss recapitulates heritable impacts of paternal cigarette smoke exposure

Murphy, Patrick J., Guo, Jingtao, Jenkins, Timothy G., James, Emma R., Hoidal, John R., Huecksteadt, Thomas, Broberg, Dallin S., Hotaling, James M., Alonso, David F., Carrell, Douglas T., Cairns, Brad

Journal:

Année:

2020

Fichier:

PDF, 6.52 MB

2020

26

Behavioral and brain- transcriptomic synchronization between the two opponents of a fighting pair of the fish Betta splendens

Vu, Trieu-Duc, Iwasaki, Yuki, Shigenobu, Shuji, Maruko, Akiko, Oshima, Kenshiro, Iioka, Erica, Huang, Chao-Li, Abe, Takashi, Tamaki, Satoshi, Lin, Yi-Wen, Chen, Chih-Kuan, Lu, Mei-Yeh, Hojo, Masaru, W

Journal:

Année:

2020

Fichier:

PDF, 3.11 MB

2020

27

ROS regulation of RAS and vulva development in Caenorhabditis elegans

Kramer-Drauberg, Maximilian, Liu, Ju-Ling, Desjardins, David, Wang, Ying, Branicky, Robyn, Hekimi, Siegfried, Ashrafi, Kaveh

Journal:

Année:

2020

Fichier:

PDF, 2.83 MB

2020

28

Estimation of non-null SNP effect size distributions enables the detection of enriched genes underlying complex traits

Cheng, Wei, Ramachandran, Sohini, Crawford, Lorin, Marchini, Jonathan

Journal:

Année:

2020

Fichier:

PDF, 4.22 MB

2020

29

VolcanoFinder: Genomic scans for adaptive introgression

Setter, Derek, Mousset, Sylvain, Cheng, Xiaoheng, Nielsen, Rasmus, DeGiorgio, Michael, Hermisson, Joachim, Buerkle, Alex

Journal:

Année:

2020

Fichier:

PDF, 7.70 MB

2020

30

The role of ROC75 as a daytime component of the circadian oscillator in Chlamydomonas reinhardtii

Matsuo, Takuya, Iida, Takahiro, Ohmura, Ayumi, Gururaj, Malavika, Kato, Daisaku, Mutoh, Risa, Ihara, Kunio, Ishiura, Masahiro, Somers, David E.

Journal:

Année:

2020

Fichier:

PDF, 1.68 MB

2020

31

A conserved, N-terminal tyrosine signal directs Ras for inhibition by Rabex-5

Washington, Chalita, Chernet, Rachel, Gokhale, Rewatee H., Martino-Cortez, Yesenia, Liu, Hsiu-Yu, Rosenberg, Ashley M., Shahar, Sivan, Pfleger, Cathie M., Treisman, Jessica Esther

Journal:

Année:

2020

Fichier:

PDF, 14.50 MB

2020

32

Overlapping functions and protein-protein interactions of LRR-extensins in Arabidopsis

Herger, Aline, Gupta, Shibu, Kadler, Gabor, Franck, Christina Maria, Boisson-Dernier, AurÃ©lien, Ringli, Christoph, Muday, Gloria K.

Journal:

Année:

2020

Fichier:

PDF, 9.73 MB

2020

33

NatB regulates Rb mutant cell death and tumor growth by modulating EGFR/MAPK signaling through the N-end rule pathways

Sheng, Zhentao, Du, Wei, Perrimon, Norbert

Journal:

Année:

2020

Fichier:

PDF, 30.36 MB

2020

34

Regulation of epithelial integrity and organ growth by Tctp and Coracle in Drosophila

Lee, Sung-Ryeong, Hong, Sung-Tae, Choi, Kwang-Wook, Barsh, Gregory S.

Journal:

Année:

2020

Fichier:

PDF, 37.01 MB

2020

35

Proteomic profiling of the monothiol glutaredoxin Grx3 reveals its global role in the regulation of iron dependent processes

Alkafeef, Selma S., Lane, Shelley, Yu, Clinton, Zhou, Tingting, Solis, Norma V., Filler, Scott G., Huang, Lan, Liu, Haoping, Snyder, Michael

Journal:

Année:

2020

Fichier:

PDF, 4.50 MB

2020

36

Pax6 organizes the anterior eye segment by guiding two distinct neural crest waves

Takamiya, Masanari, Stegmaier, Johannes, Kobitski, Andrei Yu, Schott, Benjamin, Weger, Benjamin D., Margariti, Dimitra, Cereceda Delgado, Angel R., Gourain, Victor, Scherr, Tim, Yang, Lixin, Sorge, Se

Journal:

Année:

2020

Fichier:

PDF, 35.25 MB

2020

37

A Bayesian method to estimate variant-induced disease penetrance

Kroncke, Brett M., Smith, Derek K., Zuo, Yi, Glazer, Andrew M., Roden, Dan M., Blume, Jeffrey D., Biesecker, Leslie

Journal:

Année:

2020

Fichier:

PDF, 3.82 MB

2020

38

Reciprocal regulation between nicotinamide adenine dinucleotide metabolism and abscisic acid and stress response pathways in Arabidopsis

Hong, Yechun, Wang, Zhen, Shi, Huazhong, Yao, Juanjuan, Liu, Xue, Wang, Fuxing, Zeng, Liang, Xie, Zhi, Zhu, Jian-Kang, Copenhaver, Gregory P.

Journal:

Année:

2020

Fichier:

PDF, 17.12 MB

2020

39

Thyroid hormone receptor beta mutations alter photoreceptor development and function in Danio rerioÂ (zebrafish)

Deveau, Ciana, Jiao, Xiaodong, Suzuki, Sachihiro C., Krishnakumar, Asha, Yoshimatsu, Takeshi, Hejtmancik, J Fielding, Nelson, Ralph F., Stenkamp, Deborah

Journal:

Année:

2020

Fichier:

PDF, 19.49 MB

2020

40

Protein-protein interaction network controlling establishment and maintenance of switchable cell polarity

Carreira, LuÃs AntÃ³nio Menezes, Tostevin, Filipe, Gerland, Ulrich, SÃ¸gaard-Andersen, Lotte, Lew, Daniel J.

Journal:

Année:

2020

Fichier:

PDF, 6.82 MB

2020

41

Active transcription and Orc1 drive chromatin association of the AAA+ ATPase Pch2 during meiotic G2/prophase

Cardoso da Silva, Richard, Villar-FernÃ¡ndez, MarÃa AscensiÃ³n, Vader, Gerben, Lichten, Michael

Journal:

Année:

2020

Fichier:

PDF, 6.50 MB

2020

42

Adaptive evolution among cytoplasmic piRNA proteins leads to decreased genomic auto-immunity

Wang, Luyang, Barbash, Daniel A., Kelleher, Erin S., Betancourt, Andrea

Journal:

Année:

2020

Fichier:

PDF, 2.66 MB

2020

43

Alpha- and beta-adrenergic octopamine receptors in muscle and heart are required for Drosophila exercise adaptations

Sujkowski, Alyson, Gretzinger, Anna, Soave, Nicolette, Todi, Sokol V., Wessells, Robert, Bai, Hua

Journal:

Année:

2020

Fichier:

PDF, 10.79 MB

2020

44

Drosophila models of pathogenic copy-number variant genes show global and non-neuronal defects during development

Yusuff, Tanzeen, Jensen, Matthew, Yennawar, Sneha, Pizzo, Lucilla, Karthikeyan, Siddharth, Gould, Dagny J., Sarker, Avik, Gedvilaite, Erika, Matsui, Yurika, Iyer, Janani, Lai, Zhi-Chun, Girirajan, San

Journal:

Année:

2020

Fichier:

PDF, 5.49 MB

2020

45

The kinase Isr1 negatively regulates hexosamine biosynthesis in S. cerevisiae

Alme, Emma B., Stevenson, Erica, Krogan, Nevan J., Swaney, Danielle L., Toczyski, David P., MacGurn, Jason

Journal:

Année:

2020

Fichier:

PDF, 8.05 MB

2020

46

ÂÂÂÂÂÂWidespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropods

Lewis, Samuel H., Ross, Laura, Bain, Stevie A., Pahita, Eleni, Smith, Steven A., Cordaux, Richard, Miska, Eric A., Lenhard, Boris, Jiggins, Francis M., Sarkies, Peter, Reik, Wolf

Journal:

Année:

2020

Fichier:

PDF, 5.45 MB

2020

47

Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinsonâs disease through mitochondrial dysfunction

Kao, Chung-Yang, Xu, Mafei, Wang, Leiming, Lin, Shih-Chieh, Lee, Hui-Ju, Duraine, Lita, Bellen, Hugo J., Goldstein, David S., Tsai, Sophia Y., Tsai, Ming-Jer, Fon, Edward A.

Journal:

Année:

2020

Fichier:

PDF, 9.63 MB

2020

48

The brachyceran de novo gene PIP82, a phosphorylation target of aPKC, is essential for proper formation and maintenance of the rhabdomeric photoreceptor apical domain in Drosophila

Zelhof, Andrew C., Mahato, Simpla, Liang, Xulong, Rylee, Jonathan, Bergh, Emma, Feder, Lauren E., Larsen, Matthew E., Britt, Steven G., Friedrich, Markus, Desplan, Claude

Journal:

Année:

2020

Fichier:

PDF, 19.38 MB

2020

49

Control of mRNA translation by dynamic ribosome modification

Grenga, Lucia, Little, Richard Howard, Chandra, Govind, Woodcock, Stuart Daniel, Saalbach, Gerhard, Morris, Richard James, Malone, Jacob George, SÃ¸gaard-Andersen, Lotte

Journal:

Année:

2020

Fichier:

PDF, 12.42 MB

2020

50

Suppression of class I compensated cell enlargement by xs2Â mutation is mediated by salicylic acid signaling

Ushio, Fujikura, Ezaki, Kazune, Horiguchi, Gorou, Seo, Mitsunori, Kanno, Yuri, Kamiya, Yuji, Lenhard, Michael, Tsukaya, Hirokazu, Copenhaver, Gregory P.

Journal:

Année:

2020

Fichier:

PDF, 4.13 MB

2020

51

c-di-GMP inhibits LonA-dependent proteolysis of TfoY in Vibrio cholerae

Joshi, Avatar, Mahmoud, Samar A., Kim, Soo-Kyoung, Ogdahl, Justyne L., Lee, Vincent T., Chien, Peter, Yildiz, Fitnat H., Crosson, Sean

Journal:

Année:

2020

Fichier:

PDF, 4.55 MB

2020

52

All three mammalian MutL complexes are required for repeat expansion in a mouse cell model of the Fragile X-related disorders

Miller, Carson J., Kim, Geum-Yi, Zhao, Xiaonan, Usdin, Karen, Jinks-Robertson, Sue

Journal:

Année:

2020

Fichier:

PDF, 4.95 MB

2020

53

The facts of the matter: What is a hormone?

Karsenty, Gerard, Barsh, Gregory S.

Journal:

Année:

2020

Fichier:

PDF, 310 KB

2020

54

Lack of reproducibility in osteocalcin-deficient mice

Moriishi, Takeshi, Komori, Toshihisa, Barsh, Gregory S.

Journal:

Année:

2020

Fichier:

PDF, 231 KB

2020

55

Independent validation of experimental results requires timely and unrestricted access to animal models and reagents

Diegel, Cassandra R., Hann, Steven, Ayturk, Ugur M., Hu, Jennifer C. W., Lim, Kyung-Eun, Droscha, Casey J., Madaj, Zachary B., Foxa, Gabrielle E., Izaguirre, Isaac, Robling, Alexander G., Warman, Matt

Journal:

Année:

2020

Fichier:

PDF, 234 KB

2020

56

AXR1 affects DNA methylation independently of its role in regulating meiotic crossover localization

Christophorou, Nicolas, She, Wenjing, Long, Jincheng, Hurel, AurÃ©lie, Beaubiat, SÃ©bastien, Idir, Yassir, Tagliaro-Jahns, Marina, Chambon, AurÃ©lie, Solier, Victor, Vezon, Daniel, Grelon, Mathilde, F

Journal:

Année:

2020

Fichier:

PDF, 5.44 MB

2020

57

Fpr1, a primary target of rapamycin, functions as a transcription factor for ribosomal protein genesÂ cooperatively with Hmo1 in Saccharomyces cerevisiae

Kasahara, Koji, Nakayama, Risa, Shiwa, Yuh, Kanesaki, Yu, Ishige, Taichiro, Yoshikawa, Hirofumi, Kokubo, Tetsuro, Shore, David

Journal:

Année:

2020

Fichier:

PDF, 5.68 MB

2020

58

Nitric Oxide Mediates Neuro-Glial Interaction that Shapes Drosophila Circadian Behavior

Kozlov, Anatoly, Koch, Rafael, Nagoshi, Emi, Ewer, John

Journal:

Année:

2020

Fichier:

PDF, 15.02 MB

2020

59

JMJD6 participates in the maintenance of ribosomal DNA integrity in response to DNA damage

Fages, JÃ©rÃ©mie, Chailleux, Catherine, Humbert, Jonathan, Jang, Suk-Min, Loehr, JÃ©rÃ©my, Lambert, Jean-Philippe, CÃ´tÃ©, Jacques, Trouche, Didier, Canitrot, Yvan, Maizels, Nancy

Journal:

Année:

2020

Fichier:

PDF, 11.99 MB

2020

60

Age-of-onset information helps identify 76 genetic variants associated with allergic disease

Ferreira, Manuel A. R., Vonk, Judith M., Baurecht, HansjÃ¶rg, Marenholz, Ingo, Tian, Chao, Hoffman, Joshua D., Helmer, Quinta, Tillander, Annika, Ullemar, Vilhelmina, Lu, Yi, Grosche, Sarah, RÃ¼schend

Journal:

Année:

2020

Fichier:

PDF, 3.93 MB

2020