Volume 11; Issue 6

Main
PLoS Genetics
Volume 11; Issue 6

PLoS Genetics

Volume 11; Issue 6

1

Simultaneous DNA and RNA Mapping of Somatic Mitochondrial Mutations across Diverse Human Cancers

Stewart, James B., Alaei-Mahabadi, Babak, Sabarinathan, Radhakrishnan, Samuelsson, Tore, Gorodkin, Jan, Gustafsson, Claes M., Larsson, Erik, Opferman, Joseph

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.76 MB

english, 2015

2

The Orphan Gene dauerless Regulates Dauer Development and Intraspecific Competition in Nematodes by Copy Number Variation

Mayer, Melanie G., Rödelsperger, Christian, Witte, Hanh, Riebesell, Metta, Sommer, Ralf J., Kim, Stuart K.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 3.35 MB

english, 2015

3

Functional Assessment of Disease-Associated Regulatory Variants In Vivo Using a Versatile Dual Colour Transgenesis Strategy in Zebrafish

Bhatia, Shipra, Gordon, Christopher T., Foster, Robert G., Melin, Lucie, Abadie, Véronique, Baujat, Geneviève, Vazquez, Marie-Paule, Amiel, Jeanne, Lyonnet, Stanislas, van Heyningen, Veronica, Kleinja

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 15.36 MB

english, 2015

4

Temporal Expression Profiling Identifies Pathways Mediating Effect of Causal Variant on Phenotype

Gupta, Saumya, Radhakrishnan, Aparna, Raharja-Liu, Pandu, Lin, Gen, Steinmetz, Lars M., Gagneur, Julien, Sinha, Himanshu, Fay, Justin C.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 4.47 MB

english, 2015

5

Translational Upregulation of an Individual p21Cip1 Transcript Variant by GCN2 Regulates Cell Proliferation and Survival under Nutrient Stress

Lehman, Stacey L., Cerniglia, George J., Johannes, Gregg J., Ye, Jiangbin, Ryeom, Sandra, Koumenis, Constantinos, Clurman, Bruce E.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.99 MB

english, 2015

6

9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice

Rühl, Ralph, Krzyżosiak, Agnieszka, Niewiadomska-Cimicka, Anna, Rochel, Natacha, Szeles, Lajos, Vaz, Belén, Wietrzych-Schindler, Marta, Álvarez, Susana, Szklenar, Monika, Nagy, Laszlo, de Lera, Angel

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 2.16 MB

english, 2015

7

FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling

Zhou, Siru, Xie, Yangli, Tang, Junzhou, Huang, Junlan, Huang, Qizhao, Xu, Wei, Wang, Zuqiang, Luo, Fengtao, Wang, Quan, Chen, Hangang, Du, Xiaolan, Shen, Yue, Chen, Di, Chen, Lin, Wilkie, Andrew O. M.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 20.37 MB

english, 2015

8

Response to “Ribosome Rescue and Translation Termination at Non-standard Stop Codons by ICT1 in Mammalian Mitochondria”

Chrzanowska-Lightowlers, Zofia Maria, Lightowlers, Robert Neil, Larsson, Nils-Göran

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 157 KB

english, 2015

9

Minor Cause—Major Effect: A Novel Mode of Control of Bistable Gene Expression

Kampf, Jan, Stülke, Jörg, Kearns, Daniel B.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 170 KB

english, 2015

10

Altered Levels of Mitochondrial DNA Are Associated with Female Age, Aneuploidy, and Provide an Independent Measure of Embryonic Implantation Potential

Fragouli, Elpida, Spath, Katharina, Alfarawati, Samer, Kaper, Fiona, Craig, Andrew, Michel, Claude-Edouard, Kokocinski, Felix, Cohen, Jacques, Munne, Santiago, Wells, Dagan, Kim, Stuart K.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2015

11

Multiple In Vivo Biological Processes Are Mediated by Functionally Redundant Activities of Drosophila mir-279 and mir-996

Sun, Kailiang, Jee, David, de Navas, Luis F., Duan, Hong, Lai, Eric C., Copenhaver, Gregory P.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 4.81 MB

english, 2015

12

Multiple Changes of Gene Expression and Function Reveal Genomic and Phenotypic Complexity in SLE-like Disease

Wilbe, Maria, Kozyrev, Sergey V., Farias, Fabiana H. G., Bremer, Hanna D., Hedlund, Anna, Pielberg, Gerli R., Seppälä, Eija H., Gustafson, Ulla, Lohi, Hannes, Carlborg, Örjan, Andersson, Göran, Hansso

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 7.16 MB

english, 2015

13

The Regulatory T Cell Lineage Factor Foxp3 Regulates Gene Expression through Several Distinct Mechanisms Mostly Independent of Direct DNA Binding

Xie, Xin, Stubbington, Michael J. T., Nissen, Jesper K., Andersen, Kristian G., Hebenstreit, Daniel, Teichmann, Sarah A., Betz, Alexander G., Manley, Nancy

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 5.12 MB

english, 2015

14

Germline ETV6 Mutations Confer Susceptibility to Acute Lymphoblastic Leukemia and Thrombocytopenia

Topka, Sabine, Vijai, Joseph, Walsh, Michael F., Jacobs, Lauren, Maria, Ann, Villano, Danylo, Gaddam, Pragna, Wu, Gang, McGee, Rose B., Quinn, Emily, Inaba, Hiroto, Hartford, Christine, Pui, Ching-hon

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.95 MB

english, 2015

15

Connecting Circadian Genes to Neurodegenerative Pathways in Fruit Flies

Emery, Patrick, Taghert, Paul H.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 438 KB

english, 2015

16

The Role of piRNA-Mediated Epigenetic Silencing in the Population Dynamics of Transposable Elements in Drosophila melanogaster

Lee, Yuh Chwen G., Petrov, Dmitri A.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.63 MB

english, 2015

17

Leveraging Identity-by-Descent for Accurate Genotype Inference in Family Sequencing Data

Li, Bingshan, Wei, Qiang, Zhan, Xiaowei, Zhong, Xue, Chen, Wei, Li, Chun, Haines, Jonathan, Marchini, Jonathan

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 2.20 MB

english, 2015

18

Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping

Wallace, Chris, Cutler, Antony J, Pontikos, Nikolas, Pekalski, Marcin L, Burren, Oliver S, Cooper, Jason D, García, Arcadio Rubio, Ferreira, Ricardo C, Guo, Hui, Walker, Neil M, Smyth, Deborah J, Rich

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.80 MB

english, 2015

19

Canine Spontaneous Head and Neck Squamous Cell Carcinomas Represent Their Human Counterparts at the Molecular Level

Liu, Deli, Xiong, Huan, Ellis, Angela E., Northrup, Nicole C., Dobbin, Kevin K., Shin, Dong M., Zhao, Shaying, Hammerman, Peter

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 7.09 MB

english, 2015

20

Directed Evolution of RecA Variants with Enhanced Capacity for Conjugational Recombination

Kim, Taejin, Chitteni-Pattu, Sindhu, Cox, Benjamin L., Wood, Elizabeth A., Sandler, Steven J., Cox, Michael M., Lichten, Michael

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 9.59 MB

english, 2015

21

Genetic Changes to a Transcriptional Silencer Element Confers Phenotypic Diversity within and between Drosophila Species

Johnson, Winslow C., Ordway, Alison J., Watada, Masayoshi, Pruitt, Jonathan N., Williams, Thomas M., Rebeiz, Mark, Desplan, Claude

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 9.65 MB

english, 2015

22

A Legume Genetic Framework Controls Infection of Nodules by Symbiotic and Endophytic Bacteria

Zgadzaj, Rafal, James, Euan K., Kelly, Simon, Kawaharada, Yasuyuki, de Jonge, Nadieh, Jensen, Dorthe B., Madsen, Lene H., Radutoiu, Simona, McDowell, John M.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 8.04 MB

english, 2015

23

The Causative Gene in Chanarian Dorfman Syndrome Regulates Lipid Droplet Homeostasis in C. elegans

Xie, Meng, Roy, Richard, Ashrafi, Kaveh

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 9.50 MB

english, 2015

24

Necrotic Cells Actively Attract Phagocytes through the Collaborative Action of Two Distinct PS-Exposure Mechanisms

Li, Zao, Venegas, Victor, Nagaoka, Yuji, Morino, Eri, Raghavan, Prashant, Audhya, Anjon, Nakanishi, Yoshinobu, Zhou, Zheng, Garsin, Danielle A.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 4.94 MB

english, 2015

25

A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase

Killedar, Anagha, Stutz, Michael D., Sobinoff, Alexander P., Tomlinson, Christopher G., Bryan, Tracy M., Beesley, Jonathan, Chenevix-Trench, Georgia, Reddel, Roger R., Pickett, Hilda A., Freedman, Mat

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 5.64 MB

english, 2015

26

In Vivo Senescence in the Sbds-Deficient Murine Pancreas: Cell-Type Specific Consequences of Translation Insufficiency

Tourlakis, Marina E., Zhang, Siyi, Ball, Heather L., Gandhi, Rikesh, Liu, Hongrui, Zhong, Jian, Yuan, Julie S., Guidos, Cynthia J., Durie, Peter R., Rommens, Johanna M., Ruggero, Davide

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 19.20 MB

english, 2015

27

Replication and Active Partition of Integrative and Conjugative Elements (ICEs) of the SXT/R391 Family: The Line between ICEs and Conjugative Plasmids Is Getting Thinner

Carraro, Nicolas, Poulin, Dominique, Burrus, Vincent, Waldor, Matthew K.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 2.73 MB

english, 2015

28

MreB-Dependent Inhibition of Cell Elongation during the Escape from Competence in Bacillus subtilis

Mirouze, Nicolas, Ferret, Cécile, Yao, Zhizhong, Chastanet, Arnaud, Carballido-López, Rut, Søgaard-Andersen, Lotte

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 3.26 MB

english, 2015

29

Multilayered Organization of Jasmonate Signalling in the Regulation of Root Growth

Gasperini, Debora, Chételat, Aurore, Acosta, Ivan F., Goossens, Jonas, Pauwels, Laurens, Goossens, Alain, Dreos, René, Alfonso, Esteban, Farmer, Edward E., Yu, Hao

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 10.19 MB

english, 2015

30

Transfer RNAs Mediate the Rapid Adaptation of Escherichia coli to Oxidative Stress

Zhong, Jiayong, Xiao, Chuanle, Gu, Wei, Du, Gaofei, Sun, Xuesong, He, Qing-Yu, Zhang, Gong, Ibba, Michael

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 2.23 MB

english, 2015

31

Regulation of Insulin Receptor Trafficking by Bardet Biedl Syndrome Proteins

Starks, Rachel D., Beyer, Andreas M., Guo, Deng Fu, Boland, Lauren, Zhang, Qihong, Sheffield, Val C., Rahmouni, Kamal

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 5.20 MB

english, 2015

32

Correction: Inhibition of Telomere Recombination by Inactivation of KEOPS Subunit Cgi121 Promotes Cell Longevity

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 119 KB

english, 2015

33

Correction: CAPER Is Vital for Energy and Redox Homeostasis by Integrating Glucose-Induced Mitochondrial Functions via ERR-α-Gabpa and Stress-Induced Adaptive Responses via NF-κB-cMYC

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 125 KB

english, 2015

34

Correction: The Arabidopsis DNA Polymerase δ Has a Role in the Deposition of Transcriptionally Active Epigenetic Marks, Development and Flowering

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 127 KB

english, 2015

35

Correction: Genomic Location of the Major Ribosomal Protein Gene Locus Determines Vibrio cholerae Global Growth and Infectivity

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 124 KB

english, 2015

36

Correction: Bacterial Infection Drives the Expression Dynamics of microRNAs and Their isomiRs

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 119 KB

english, 2015

37

Correction: The Escherichia coli Small Protein MntS and Exporter MntP Optimize the Intracellular Concentration of Manganese

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 124 KB

english, 2015

38

Reproductive Mode and the Evolution of Genome Size and Structure in Caenorhabditis Nematodes

Fierst, Janna L., Willis, John H., Thomas, Cristel G., Wang, Wei, Reynolds, Rose M., Ahearne, Timothy E., Cutter, Asher D., Phillips, Patrick C., Blaxter, Mark

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 2.64 MB

english, 2015

39

Correction: Monoallelic Loss of the Imprinted Gene Grb10 Promotes Tumor Formation in Irradiated Nf1+/- Mice

Mroue, Rana, Huang, Brian, Braunstein, Steve, Firestone, Ari J., Nakamura, Jean L.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 117 KB

english, 2015

40

Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In Vivo

Preuße, Kristina, Tveriakhina, Lena, Schuster-Gossler, Karin, Gaspar, Cláudia, Rosa, Alexandra Isabel, Henrique, Domingos, Gossler, Achim, Stauber, Michael, Copenhaver, Gregory P.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 16.08 MB

english, 2015

41

Ancestral Chromatin Configuration Constrains Chromatin Evolution on Differentiating Sex Chromosomes in Drosophila

Zhou, Qi, Bachtrog, Doris, Akhtar, Asifa

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 3.82 MB

english, 2015

42

Separable Crossover-Promoting and Crossover-Constraining Aspects of Zip1 Activity during Budding Yeast Meiosis

Voelkel-Meiman, Karen, Johnston, Cassandra, Thappeta, Yashna, Subramanian, Vijayalakshmi V., Hochwagen, Andreas, MacQueen, Amy J., Sekelsky, Jeff

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 10.72 MB

english, 2015

43

Correction: Genomic Selection and Association Mapping in Rice (Oryza sativa): Effect of Trait Genetic Architecture, Training Population Composition, Marker Number and Statistical Model on Accuracy of Rice Genomic Selection in Elite, Tropical Rice Breeding Lines

Spindel, Jennifer, Begum, Hasina, Akdemir, Deniz, Virk, Parminder, Collard, Bertrand, Redoña, Edilberto, Atlin, Gary, Jannink, Jean-Luc, McCouch, Susan R.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 969 KB

english, 2015

44

Silencing of DNase Colicin E8 Gene Expression by a Complex Nucleoprotein Assembly Ensures Timely Colicin Induction

Kamenšek, Simona, Browning, Douglas F., Podlesek, Zdravko, Busby, Stephen J. W., Žgur-Bertok, Darja, Butala, Matej, Hughes, Diarmaid

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 3.28 MB

english, 2015

45

Drosophila Lipophorin Receptors Recruit the Lipoprotein LTP to the Plasma Membrane to Mediate Lipid Uptake

Rodríguez-Vázquez, Míriam, Vaquero, David, Parra-Peralbo, Esmeralda, Mejía-Morales, John E., Culi, Joaquim, Thummel, Carl S.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 17.98 MB

english, 2015

46

Expression of Concern: RNAi-Dependent and Independent Control of LINE1 Accumulation and Mobility in Mouse Embryonic Stem Cells

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 118 KB

english, 2015

47

Abnormal Activation of BMP Signaling Causes Myopathy in Fbn2 Null Mice

Sengle, Gerhard, Carlberg, Valerie, Tufa, Sara F., Charbonneau, Noe L., Smaldone, Silvia, Carlson, Eric J., Ramirez, Francesco, Keene, Douglas R., Sakai, Lynn Y., Cox, Gregory A.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 21.59 MB

english, 2015