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Volume 16; Issue 8
Main
PLoS Computational Biology
Volume 16; Issue 8
PLoS Computational Biology
Volume 16; Issue 8
1
Optimising efficacy of antibiotics against systemic infection by varying dosage quantities and times
Hoyle, Andy
,
Cairns, David
,
Paterson, Iona
,
McMillan, Stuart
,
Ochoa, Gabriela
,
Desbois, Andrew P.
,
Antia, Rustom
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 2.77 MB
Vos balises:
2020
2
Multiplexing information flow through dynamic signalling systems
Minas, Giorgos
,
Woodcock, Dan J.
,
Ashall, Louise
,
Harper, Claire V.
,
White, Michael R. H.
,
Rand, David A.
,
Csikász-Nagy, Attila
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 5.20 MB
Vos balises:
2020
3
Flexible neural connectivity under constraints on total connection strength
Ocker, Gabriel Koch
,
Buice, Michael A.
,
Beck, Jeff
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 4.09 MB
Vos balises:
2020
4
Predicting precision grip grasp locations on three-dimensional objects
Klein, Lina K.
,
Maiello, Guido
,
Paulun, Vivian C.
,
Fleming, Roland W.
,
Einhäuser, Wolfgang
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 16.94 MB
Vos balises:
2020
5
Effect of magnitude and variability of energy of activation in multisite ultrasensitive biochemical processes
Lagunes, Leonila
,
Bardwell, Lee
,
Enciso, German A.
,
Faeder, James R.
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 5.10 MB
Vos balises:
2020
6
Achieving stable dynamics in neural circuits
Kozachkov, Leo
,
Lundqvist, Mikael
,
Slotine, Jean-Jacques
,
Miller, Earl K.
,
Haith, Adrian M
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 2.07 MB
Vos balises:
2020
7
Reliable estimation of membrane curvature for cryo-electron tomography
Salfer, Maria
,
Collado, Javier F.
,
Baumeister, Wolfgang
,
Fernández-Busnadiego, Rubén
,
MartÃnez-Sánchez, Antonio
,
Saucerman, Jeffrey J.
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 29.57 MB
Vos balises:
2020
8
Facilitating the propagation of spiking activity in feedforward networks by including feedback
Rezaei, Hedyeh
,
Aertsen, Ad
,
Kumar, Arvind
,
Valizadeh, Alireza
,
Gershman, Samuel J.
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 5.52 MB
Vos balises:
2020
9
A machine learning and network framework to discover new indications for small molecules
Gilvary, Coryandar
,
Elkhader, Jamal
,
Madhukar, Neel
,
Henchcliffe, Claire
,
Goncalves, Marcus D.
,
Elemento, Olivier
,
Schlessinger, Avner
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 3.54 MB
Vos balises:
2020
10
Presynaptic inhibition rapidly stabilises recurrent excitation in the face of plasticity
Naumann, Laura Bella
,
Sprekeler, Henning
,
Rubin, Jonathan
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 3.51 MB
Vos balises:
2020
11
In silico co-factor balance estimation using constraint-based modelling informs metabolic engineering in Escherichia coli
de Arroyo Garcia, Laura
,
Jones, Patrik R.
,
Wallqvist, Anders
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 9.88 MB
Vos balises:
2020
12
Order matters: How covert value updating during sequential option sampling shapes economic preference
Hu, Chen
,
Domenech, Philippe
,
Pessiglione, Mathias
,
Soltani, Alireza
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 2.39 MB
Vos balises:
2020
13
Genotype networks of 80 quantitative Arabidopsis thaliana phenotypes reveal phenotypic evolvability despite pervasive epistasis
Schweizer, Gabriel
,
Wagner, Andreas
,
Usadel, Björn
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 3.09 MB
Vos balises:
2020
14
Information transmission from NFkB signaling dynamics to gene expression
Maity, Alok
,
Wollman, Roy
,
Igoshin, Oleg A.
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 3.29 MB
Vos balises:
2020
15
A Bayesian phylogenetic hidden Markov model for B cell receptor sequence analysis
Dhar, Amrit
,
Ralph, Duncan K.
,
Minin, Vladimir N.
,
Matsen, Frederick A.
,
Kosakovsky Pond, Sergei L.
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 4.70 MB
Vos balises:
2020
16
Machine Learning based histology phenotyping to investigate the epidemiologic and genetic basis of adipocyte morphology and cardiometabolic traits
Glastonbury, Craig A.
,
Pulit, Sara L.
,
Honecker, Julius
,
Censin, Jenny C.
,
Laber, Samantha
,
Yaghootkar, Hanieh
,
Rahmioglu, Nilufer
,
Pastel, Emilie
,
Kos, Katerina
,
Pitt, Andrew
,
Hudson, Michelle
,
NellÃ
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 2.65 MB
Vos balises:
2020
17
Inferring the ancestry of parents and grandparents from genetic data
Pei, Jingwen
,
Zhang, Yiming
,
Nielsen, Rasmus
,
Wu, Yufeng
,
Kosakovsky Pond, Sergei L.
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 3.34 MB
Vos balises:
2020
18
Drug-target binding quantitatively predicts optimal antibiotic dose levels in quinolones
Clarelli, Fabrizio
,
Palmer, Adam
,
Singh, Bhupender
,
Storflor, Merete
,
Lauksund, Silje
,
Cohen, Ted
,
Abel, Sören
,
Abel zur Wiesch, Pia
,
Kasson, Peter M.
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 4.17 MB
Vos balises:
2020
19
Deconvolving the contributions of cell-type heterogeneity on cortical gene expression
Patrick, Ellis
,
Taga, Mariko
,
Ergun, Ayla
,
Ng, Bernard
,
Casazza, William
,
Cimpean, Maria
,
Yung, Christina
,
Schneider, Julie A.
,
Bennett, David A.
,
Gaiteri, Chris
,
De Jager, Philip L.
,
Bradshaw, Elizab
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 3.38 MB
Vos balises:
2020
20
Cardiac and renal function interactions in heart failure with reduced ejection fraction: A mathematical modeling analysis
Yu, Hongtao
,
Basu, Sanchita
,
Hallow, K. Melissa
,
Beard, Daniel A
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 3.86 MB
Vos balises:
2020
21
Mathematical model and tool to explore shorter multi-drug therapy options for active pulmonary tuberculosis
Fors, John
,
Strydom, Natasha
,
Fox, William S.
,
Keizer, Ron J.
,
Savic, Radojka M.
,
Gallo, James
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 8.18 MB
Vos balises:
2020
22
Modeling time-varying brain networks with a self-tuning optimized Kalman filter
Pascucci, D.
,
Rubega, M.
,
Plomp, G.
,
Battaglia, Francesco P.
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 5.35 MB
Vos balises:
2020
23
Engineering recurrent neural networks from task-relevant manifolds and dynamics
Pollock, Eli
,
Jazayeri, Mehrdad
,
Soltani, Alireza
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 5.24 MB
Vos balises:
2020
24
Modeling microbial cross-feeding at intermediate scale portrays community dynamics and species coexistence
Liao, Chen
,
Wang, Tong
,
Maslov, Sergei
,
Xavier, Joao B.
,
Grilli, Jacopo
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 5.84 MB
Vos balises:
2020
25
JBrowse Connect: A server API to connect JBrowse instances and users
Yao, Eric
,
Buels, Robert
,
Stein, Lincoln
,
Sen, Taner Z.
,
Holmes, Ian
,
Darling, Aaron E.
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 4.71 MB
Vos balises:
2020
26
Visual perception of liquids: Insights from deep neural networks
van Assen, Jan Jaap R.
,
Nishida, Shinâya
,
Fleming, Roland W.
,
Marinazzo, Daniele
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 7.60 MB
Vos balises:
2020
27
Understanding multivariate brain activity: Evaluating the effect of voxelwise noise correlations on population codes in functional magnetic resonance imaging
Zhang, Ru-Yuan
,
Wei, Xue-Xin
,
Kay, Kendrick
,
Jbabdi, Saad
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 9.93 MB
Vos balises:
2020
28
Dynamic estimation of auditory temporal response functions via state-space models with Gaussian mixture process noise
Miran, Sina
,
Presacco, Alessandro
,
Simon, Jonathan Z.
,
Fu, Michael C.
,
Marcus, Steven I.
,
Babadi, Behtash
,
Marinazzo, Daniele
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 8.57 MB
Vos balises:
2020
29
Epithelial organ shape is generated by patterned actomyosin contractility and maintained by the extracellular matrix
Nematbakhsh, Ali
,
Levis, Megan
,
Kumar, Nilay
,
Chen, Weitao
,
Zartman, Jeremiah J.
,
Alber, Mark
,
Maini, Philip K.
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 21.22 MB
Vos balises:
2020
30
Managing disease outbreaks: The importance of vector mobility and spatially heterogeneous control
Demers, Jeffery
,
Bewick, Sharon
,
Agusto, Folashade
,
Caillouët, Kevin A.
,
Fagan, William F.
,
Robertson, Suzanne L.
,
Kouyos, Roger Dimitri
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 5.48 MB
Vos balises:
2020
31
Mathematical modelling reveals cellular dynamics within tumour spheroids
Bull, Joshua A.
,
Mech, Franziska
,
Quaiser, Tom
,
Waters, Sarah L.
,
Byrne, Helen M.
,
Finley, Stacey
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 21.80 MB
Vos balises:
2020
32
Simulating flow induced migration in vascular remodelling
Tabibian, Ashkan
,
Ghaffari, Siavash
,
Vargas, Diego A.
,
Van Oosterwyck, Hans
,
Jones, Elizabeth A. V.
,
Diamond, Scott L
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 10.15 MB
Vos balises:
2020
33
A novel single-cell based method for breast cancer prognosis
Li, Xiaomei
,
Liu, Lin
,
Goodall, Gregory J.
,
Schreiber, Andreas
,
Xu, Taosheng
,
Li, Jiuyong
,
Le, Thuc D.
,
Ioshikhes, Ilya
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 2.52 MB
Vos balises:
2020
34
Cell signaling model for arterial mechanobiology
Irons, Linda
,
Humphrey, Jay D.
,
Saucerman, Jeffrey J.
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 3.67 MB
Vos balises:
2020
35
Firing rate homeostasis counteracts changes in stability of recurrent neural networks caused by synapse loss in Alzheimerâs disease
Bachmann, Claudia
,
Tetzlaff, Tom
,
Duarte, Renato
,
Morrison, Abigail
,
Rotter, Stefan
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 15.19 MB
Vos balises:
2020
36
Model-driven analysis of mutant fitness experiments improves genome-scale metabolic models of Zymomonas mobilis ZM4
Ong, Wai Kit
,
Courtney, Dylan K.
,
Pan, Shu
,
Andrade, Ramon Bonela
,
Kiley, Patricia J.
,
Pfleger, Brian F.
,
Reed, Jennifer L.
,
Maranas, Costas D.
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 1.91 MB
Vos balises:
2020
37
Ten simple rules to power drug discovery with data science
Ferrero, Enrico
,
Brachat, Sophie
,
Jenkins, Jeremy L.
,
Marc, Philippe
,
Skewes-Cox, Peter
,
Altshuler, Robert C.
,
Gubser Keller, Caroline
,
Kauffmann, Audrey
,
Sassaman, Erik K.
,
Laramie, Jason M.
,
Schoebe
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 781 KB
Vos balises:
2020
38
In silico discovery and biological validation of ligands of FAD synthase, a promising new antimicrobial target
Lans, Isaias
,
Anoz-Carbonell, Ernesto
,
Palacio-RodrÃguez, Karen
,
AÃnsa, José Antonio
,
Medina, Milagros
,
Cossio, Pilar
,
MacKerell, Alexander
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 2.13 MB
Vos balises:
2020
39
A computational model of induced pluripotent stem-cell derived cardiomyocytes for high throughput risk stratification of KCNQ1 genetic variants
Kernik, Divya C.
,
Yang, Pei-Chi
,
Kurokawa, Junko
,
Wu, Joseph C.
,
Clancy, Colleen E.
,
Niederer, Steven A.
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 3.58 MB
Vos balises:
2020
40
Ten simple rules to increase computational skills among biologists with Code Clubs
Hagan, Ada K.
,
Lesniak, Nicholas A.
,
Balunas, Marcy J.
,
Bishop, Lucas
,
Close, William L.
,
Doherty, Matthew D.
,
Elmore, Amanda G.
,
Flynn, Kaitlin J.
,
Hannigan, Geoffrey D.
,
Koumpouras, Charlie C.
,
Jeni
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 285 KB
Vos balises:
2020
41
Computer-guided binding mode identification and affinity improvement of an LRR protein binder without structure determination
Choi, Yoonjoo
,
Jeong, Sukyo
,
Choi, Jung-Min
,
Ndong, Christian
,
Griswold, Karl E.
,
Bailey-Kellogg, Chris
,
Kim, Hak-Sung
,
Punta, Marco
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 9.30 MB
Vos balises:
2020
42
Determining the interaction status and evolutionary fate of duplicated homomeric proteins
Mallik, Saurav
,
Tawfik, Dan S.
,
Shakhnovich, Eugene I.
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 3.17 MB
Vos balises:
2020
43
Early exposure to broadly neutralizing antibodies may trigger a dynamical switch from progressive disease to lasting control of SHIV infection
Desikan, Rajat
,
Raja, Rubesh
,
Dixit, Narendra M.
,
Yates, Andrew J.
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 3.35 MB
Vos balises:
2020
44
Tumor vascular status controls oxygen delivery facilitated by infused polymerized hemoglobins with varying oxygen affinity
Belcher, Donald A.
,
Lucas, Alfredo
,
Cabrales, Pedro
,
Palmer, Andre F.
,
Beard, Daniel A
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 5.98 MB
Vos balises:
2020
45
Template-based mapping of dynamic motifs in tissue morphogenesis
Stern, Tomer
,
Shvartsman, Stanislav Y.
,
Wieschaus, Eric F.
,
Umulis, David
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 2.46 MB
Vos balises:
2020
46
Vector genetics, insecticide resistance and gene drives: An agent-based modeling approach to evaluate malaria transmission and elimination
Selvaraj, Prashanth
,
Wenger, Edward A.
,
Bridenbecker, Daniel
,
Windbichler, Nikolai
,
Russell, Jonathan R.
,
Gerardin, Jaline
,
Bever, Caitlin A.
,
Nikolov, Milen
,
Davenport, Miles P.
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 1.74 MB
Vos balises:
2020
47
Modeling microbial metabolic trade-offs in a chemostat
Li, Zhiyuan
,
Liu, Bo
,
Li, Sophia Hsin-Jung
,
King, Christopher G.
,
Gitai, Zemer
,
Wingreen, Ned S.
,
Grilli, Jacopo
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 7.19 MB
Vos balises:
2020
48
Buildup and bistability in auditory streaming as an evidence accumulation process with saturation
Nguyen, Quynh-Anh
,
Rinzel, John
,
Curtu, Rodica
,
Einhäuser, Wolfgang
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 3.78 MB
Vos balises:
2020
49
Real-time estimation of disease activity in emerging outbreaks using internet search information
Aiken, Emily L.
,
McGough, Sarah F.
,
Majumder, Maimuna S.
,
Wachtel, Gal
,
Nguyen, Andre T.
,
Viboud, Cecile
,
Santillana, Mauricio
,
Pulliam, Juliet R.C.
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 2.09 MB
Vos balises:
2020
50
Task-evoked activity quenches neural correlations and variability across cortical areas
Ito, Takuya
,
Brincat, Scott L.
,
Siegel, Markus
,
Mill, Ravi D.
,
He, Biyu J.
,
Miller, Earl K.
,
Rotstein, Horacio G.
,
Cole, Michael W.
,
Marinazzo, Daniele
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 4.36 MB
Vos balises:
2020
51
Partitioning stable and unstable expression level variation in cell populations: A theoretical framework and its application to the T cell receptor
Guzella, Thiago S.
,
Barreto, Vasco M.
,
Carneiro, Jorge
,
Meier-Schellersheim, Martin
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 2.70 MB
Vos balises:
2020
52
A steady-state model of microbial acclimation to substrate limitation
Casey, John R.
,
Follows, Michael J.
,
Cannon, William
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 1.48 MB
Vos balises:
2020
53
Combining hypoxia-activated prodrugs and radiotherapy in silico: Impact of treatment scheduling and the intra-tumoural oxygen landscape
Hamis, Sara
,
Kohandel, Mohammad
,
Dubois, Ludwig J.
,
Yaromina, Ala
,
Lambin, Philippe
,
Powathil, Gibin G.
,
Lazzara, Matthew J.
Journal:
PLoS Computational Biology
Année:
2020
Fichier:
PDF, 3.44 MB
Vos balises:
2020
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