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Volume 33; Issue 2

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Pharmaceutical Research
Volume 33; Issue 2

Pharmaceutical Research

Volume 33; Issue 2

1

Physiologically-Based Pharmacokinetic and Pharmacodynamic Modeling for the Inhibition of Acetylcholinesterase by Acotiamide, A Novel Gastroprokinetic Agent for the Treatment of Functional Dyspepsia, in Rat Stomach

Yoshii, Kazuyoshi, Iikura, Minami, Hirayama, Masamichi, Toda, Ryoko, Kawabata, Yoshihiro

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 653 KB

english, 2016

2

Applicability of Bipolar Charge Analyzer (BOLAR) in Characterizing the Bipolar Electrostatic Charge Profile of Commercial Metered Dose Inhalers (MDIs)

Leung, Sharon Shui Yee, Chiow, Adam Chong Ming, Ukkonen, Ari, Chan, Hak-Kim

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2016

3

Curcumin Nanoparticles Attenuate Production of Pro-inflammatory Markers in Lipopolysaccharide-Induced Macrophages

Lee, Wing-Hin, Loo, Ching-Yee, Young, Paul M., Rohanizadeh, Ramin, Traini, Daniela

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 2.12 MB

english, 2016

4

BiosimilarityVersusManufacturing Change: Two Distinct Concepts

Declerck, Paul, Farouk-Rezk, Mourad, Rudd, Pauline M.

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 520 KB

english, 2016

5

Thermodynamic Changes Induced by Intermolecular Interaction Between Ibuprofen and Chitosan: Effect on Crystal Habit, Solubility andIn VitroRelease Kinetics of Ibuprofen

Abioye, Amos Olusegun, Armitage, Rachel, Kola-Mustapha, Adeola Tawakalitu

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 3.06 MB

english, 2016

6

Temperature/pH Responsive Hydrogels Based on Poly(ethylene glycol) and Functionalized Poly(e-caprolactone) Block Copolymers for Controlled Delivery of Macromolecules

Nikouei, Nazila Safaei, Ghasemi, Nasim, Lavasanifar, Afsaneh

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2016

7

Predicting Mouse Liver Microsomal Stability with “Pruned” Machine Learning Models and Public Data

Perryman, Alexander L., Stratton, Thomas P., Ekins, Sean, Freundlich, Joel S.

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 1.91 MB

english, 2016

8

Pharmacokinetic Properties of a Noveld-Peptide Developed to be Therapeutically Active Against Toxic β-Amyloid Oligomers

L. H. E. Leithold, N. Jiang, J. Post, T. Ziehm, E. Schartmann, J. Kutzsche, N. J. Shah, J. Breitkreutz, K. Langen, A. Willuweit, D. Willbold

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 849 KB

english, 2016

9

Modulation of Cell-Mediated Immunity to Suppress High Fat Diet-Induced Obesity and Insulin Resistance

L. Yan, K. Song, M. Gao, S. Qu, D. Liu

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 3.85 MB

english, 2016

10

Folate-Conjugated pH-Responsive Nanocarrier Designed for Active Tumor Targeting and Controlled Release of Gemcitabine

Pourjavadi, Ali, Tehrani, Zahra Mazaheri, Moghanaki, Azardokht Abedin

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 3.75 MB

english, 2016

11

A Comparison of the Pharmacokinetics and Pulmonary Lymphatic Exposure of a Generation 4 PEGylated Dendrimer Following Intravenous and Aerosol Administration to Rats and Sheep

Ryan, Gemma M., Bischof, Robert J., Enkhbaatar, Perenlei, McLeod, Victoria M., Chan, Linda J., Jones, Seth A., Owen, David J., Porter, Christopher J. H., Kaminskas, Lisa M.

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2016

12

Comparative Effects of Metal-Catalyzed Oxidizing Systems on Carbonylation and Integrity of Therapeutic Proteins

Kryndushkin, Dmitry, Rao, V. Ashutosh

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2016

13

Model-Based Optimisation of Deferoxamine Chelation Therapy

Bellanti, Francesco, Del Vecchio, Giovanni C., Putti, Maria C., Cosmi, Carlo, Fotzi, Ilaria, Bakshi, Suruchi D., Danhof, Meindert, Della Pasqua, Oscar

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2016

14

2D1HN,15N Correlated NMR Methods at Natural Abundance for Obtaining Structural Maps and Statistical Comparability of Monoclonal Antibodies

Arbogast, Luke W., Brinson, Robert G., Formolo, Trina, Hoopes, J. Todd, Marino, John P.

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 3.19 MB

english, 2016

15

Oxaprozin-Loaded Lipid Nanoparticles towards Overcoming NSAIDs Side-Effects

Lopes-de-Araújo, José, Neves, Ana Rute, Gouveia, Virgínia M., Moura, Catarina C., Nunes, Cláudia, Reis, Salette

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2016

16

Liposome Formation Using a Coaxial Turbulent Jet in Co-Flow

Costa, Antonio P., Xu, Xiaoming, Khan, Mansoor A., Burgess, Diane J.

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 3.63 MB

english, 2016

17

Aerosolized Non-viral Nucleic Acid Delivery in the Vaginal Tract of Pigs

Remaut, Katrien, De Clercq, Evelien, Andries, Oliwia, Rombouts, Koen, Van Gils, Matthias, Cicchelero, Laetitia, Vandenbussche, Ian, Van Praet, Sarah, Benito, Juan Manuel, Fernandéz, José Manuel Garcia

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2016

18

Preclinical Pharmacokinetics Evaluation of Anti-heparin-binding EGF-like Growth Factor (HB-EGF) Monoclonal Antibody Using Cynomolgus Monkeysvia89Zr-immuno-PET Study and the Determination of Drug Concentrations in Serum and Cerebrospinal Fluid

Kasai, Noriyuki, Adachi, Maiko, Yamano, Kazuya

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 949 KB

english, 2016

19

Sodium Acetate Coated Tenofovir-Loaded Chitosan Nanoparticles for Improved Physico-Chemical Properties

Ngo, Albert N., Ezoulin, Miezan J. M., Murowchick, James B., Gounev, Andrea D., Youan, Bi-Botti C.

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 4.05 MB

english, 2016

20

Increased Plasma Concentrations of Unbound SN-38, the Active Metabolite of Irinotecan, in Cancer Patients with Severe Renal Failure

Fujita, Ken-ichi, Masuo, Yusuke, Okumura, Hidenori, Watanabe, Yusuke, Suzuki, Hiromichi, Sunakawa, Yu, Shimada, Ken, Kawara, Kaori, Akiyama, Yuko, Kitamura, Masanori, Kunishima, Munetaka, Sasaki, Yasu

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 815 KB

english, 2016

21

Factors Governing the Precision of Subvisible Particle Measurement Methods – A Case Study with a Low-Concentration Therapeutic Protein Product in a Prefilled Syringe

Ríos Quiroz, Anacelia, Lamerz, Jens, Da Cunha, Thierry, Boillon, Adeline, Adler, Michael, Finkler, Christof, Huwyler, Joerg, Schmidt, Roland, Mahler, Hanns-Christian, Koulov, Atanas V.

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 527 KB

english, 2016

22

Drug Permeation Characterization of Inhaled Dry Powder Formulations in Air-Liquid Interfaced Cell Layer Using an Improved, Simple Apparatus for Dispersion

Asai, Ayumu, Okuda, Tomoyuki, Sonoda, Erina, Yamauchi, Tomoyo, Kato, Saki, Okamoto, Hirokazu

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 5.77 MB

english, 2016

23

AAPS Connection

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 245 KB

english, 2016