Volume 23; Issue 4

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Nature Medicine
Volume 23; Issue 4

Nature Medicine

Volume 23; Issue 4

1

Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates

Wang, Pi-Xiao, Ji, Yan-Xiao, Zhang, Xiao-Jing, Zhao, Ling-Ping, Yan, Zhen-Zhen, Zhang, Peng, Shen, Li-Jun, Yang, Xia, Fang, Jing, Tian, Song, Zhu, Xue-Yong, Gong, Jun, Zhang, Xin, Wei, Qiao-Fang, Wang

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 3.56 MB

english, 2017

2

Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice

Beckerman, Pazit, Bi-Karchin, Jing, Park, Ae Seo Deok, Qiu, Chengxiang, Dummer, Patrick D, Soomro, Irfana, Boustany-Kari, Carine M, Pullen, Steven S, Miner, Jeffrey H, Hu, Chien-An A, Rohacs, Tibor, I

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 2.79 MB

english, 2017

3

Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes

Kracht, Maria J L, van Lummel, Menno, Nikolic, Tatjana, Joosten, Antoinette M, Laban, Sandra, van der Slik, Arno R, van Veelen, Peter A, Carlotti, Françoise, de Koning, Eelco J P, Hoeben, Rob C, Zaldu

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2017

4

EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas

Mohammad, Faizaan, Weissmann, Simon, Leblanc, Benjamin, Pandey, Deo P, Højfeldt, Jonas W, Comet, Itys, Zheng, Chunqin, Johansen, Jens Vilstrup, Rapin, Nicolas, Porse, Bo T, Tvardovskiy, Andrey, Jensen

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 2.17 MB

english, 2017

5

Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle

Misu, Hirofumi, Takayama, Hiroaki, Saito, Yoshiro, Mita, Yuichiro, Kikuchi, Akihiro, Ishii, Kiyo-aki, Chikamoto, Keita, Kanamori, Takehiro, Tajima, Natsumi, Lan, Fei, Takeshita, Yumie, Honda, Masao, T

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2017

6

Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas

Piunti, Andrea, Hashizume, Rintaro, Morgan, Marc A, Bartom, Elizabeth T, Horbinski, Craig M, Marshall, Stacy A, Rendleman, Emily J, Ma, Quanhong, Takahashi, Yoh-hei, Woodfin, Ashley R, Misharin, Alexa

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 3.08 MB

english, 2017

7

A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress

Bruno, Peter M, Liu, Yunpeng, Park, Ga Young, Murai, Junko, Koch, Catherine E, Eisen, Timothy J, Pritchard, Justin R, Pommier, Yves, Lippard, Stephen J, Hemann, Michael T

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 2.56 MB

english, 2017

8

Glucocorticoid hormone-induced chromatin remodeling enhances human hematopoietic stem cell homing and engraftment

Guo, Bin, Huang, Xinxin, Cooper, Scott, Broxmeyer, Hal E

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 648 KB

english, 2017

9

HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures

Davies, Helen, Glodzik, Dominik, Morganella, Sandro, Yates, Lucy R, Staaf, Johan, Zou, Xueqing, Ramakrishna, Manasa, Martin, Sancha, Boyault, Sandrine, Sieuwerts, Anieta M, Simpson, Peter T, King, Tar

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 1.60 MB

english, 2017

10

Gpr124 is essential for blood–brain barrier integrity in central nervous system disease

Chang, Junlei, Mancuso, Michael R, Maier, Carolina, Liang, Xibin, Yuki, Kanako, Yang, Lu, Kwong, Jeffrey W, Wang, Jing, Rao, Varsha, Vallon, Mario, Kosinski, Cynthia, Zhang, J J Haijing, Mah, Amanda T

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 4.60 MB

english, 2017

11

Targeting c-FOS and DUSP1 abrogates intrinsic resistance to tyrosine-kinase inhibitor therapy in BCR-ABL-induced leukemia

Kesarwani, Meenu, Kincaid, Zachary, Gomaa, Ahmed, Huber, Erika, Rohrabaugh, Sara, Siddiqui, Zain, Bouso, Muhammad F, Latif, Tahir, Xu, Ming, Komurov, Kakajan, Mulloy, James C, Cancelas, Jose A, Grimes

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 2.67 MB

english, 2017

12

The Drug Repurposing Hub: a next-generation drug library and information resource

Corsello, Steven M, Bittker, Joshua A, Liu, Zihan, Gould, Joshua, McCarren, Patrick, Hirschman, Jodi E, Johnston, Stephen E, Vrcic, Anita, Wong, Bang, Khan, Mariya, Asiedu, Jacob, Narayan, Rajiv, Made

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 429 KB

english, 2017

13

Refining strategies to translate genome editing to the clinic

Cornu, Tatjana I, Mussolino, Claudio, Cathomen, Toni

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2017

14

Autoimmune T cell recognition of alternative-reading-frame-encoded peptides

Wei, Jiajie, Yewdell, Jonathan W

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2017

15

Untangling the role of mutant histone H3 in diffuse intrinsic pontine glioma

Creasy, Caretha L

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2017

16

Beyond the breath: Exploring sex differences in tuberculosis outside the lungs

Katsnelson, Alla

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 1.56 MB

english, 2017

17

A curious connection: Teasing apart the link between gut microbes and lung disease

Chakradhar, Shraddha

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 969 KB

english, 2017

18

A mouse recapitulating APOL1-associated kidney disease

Winkler, Cheryl A, Nelson, George W

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 330 KB

english, 2017

19

Corrigendum: Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure

Malherbe, Stephanus T, Shenai, Shubhada, Ronacher, Katharina, Loxton, Andre G, Dolganov, Gregory, Kriel, Magdalena, Van, Tran, Chen, Ray Y, Warwick, James, Via, Laura E, Song, Taeksun, Lee, Myungsun,

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 56 KB

english, 2017

20

Erratum: Reply to “Neutrophils are not required for resolution of acute gouty arthritis in mice”

Reinwald, Christiane, Schauer, Christine, Csepregi, Janka Zsófia, Kienhöfer, Deborah, Weidner, Daniela, Malissen, Marie, Mocsai, Attila, Schett, Georg, Herrmann, Martin, Hoffmann, Markus

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 56 KB

english, 2017

21

Erratum: PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer

Brasó-Maristany, Fara, Filosto, Simone, Catchpole, Steven, Marlow, Rebecca, Quist, Jelmar, Francesch-Domenech, Erika, Plumb, Darren A, Zakka, Leila, Gazinska, Patrycja, Liccardi, Gianmaria, Meier, Pas

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 57 KB

english, 2017

22

Correction

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 560 KB

english, 2017

23

Science over speed

Journal:

Nature Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 79 KB

english, 2017