Volume 21; Issue 7

Main
Nature Medicine
Volume 21; Issue 7

Nature Medicine

Volume 21; Issue 7

1

Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR

Vizoso, Miguel, Ferreira, Humberto J, Lopez-Serra, Paula, Carmona, F Javier, Martínez-Cardús, Anna, Girotti, Maria Romina, Villanueva, Alberto, Guil, Sonia, Moutinho, Catia, Liz, Julia, Portela, Anna,

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 4.12 MB

english, 2015

2

Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients

Siravegna, Giulia, Mussolin, Benedetta, Buscarino, Michela, Corti, Giorgio, Cassingena, Andrea, Crisafulli, Giovanni, Ponzetti, Agostino, Cremolini, Chiara, Amatu, Alessio, Lauricella, Calogero, Lamba

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 673 KB

english, 2015

3

Activation of HIF-1α and LL-37 by commensal bacteria inhibits Candida albicans colonization

Fan, Di, Coughlin, Laura A, Neubauer, Megan M, Kim, Jiwoong, Kim, Min Soo, Zhan, Xiaowei, Simms-Waldrip, Tiffany R, Xie, Yang, Hooper, Lora V, Koh, Andrew Y

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2015

4

Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors

Lemos, Dario R, Babaeijandaghi, Farshad, Low, Marcela, Chang, Chih-Kai, Lee, Sunny T, Fiore, Daniela, Zhang, Regan-Heng, Natarajan, Anuradha, Nedospasov, Sergei A, Rossi, Fabio M V

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 4.76 MB

english, 2015

5

Diabetes primes neutrophils to undergo NETosis, which impairs wound healing

Wong, Siu Ling, Demers, Melanie, Martinod, Kimberly, Gallant, Maureen, Wang, Yanming, Goldfine, Allison B, Kahn, C Ronald, Wagner, Denisa D

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2015

6

Urocortin3 mediates somatostatin-dependent negative feedback control of insulin secretion

van der Meulen, Talitha, Donaldson, Cynthia J, Cáceres, Elena, Hunter, Anna E, Cowing-Zitron, Christopher, Pound, Lynley D, Adams, Michael W, Zembrzycki, Andreas, Grove, Kevin L, Huising, Mark O

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 3.58 MB

english, 2015

7

Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension

Long, Lu, Ormiston, Mark L, Yang, Xudong, Southwood, Mark, Gräf, Stefan, Machado, Rajiv D, Mueller, Matthias, Kinzel, Bernd, Yung, Lai Ming, Wilkinson, Janine M, Moore, Stephen D, Drake, Kylie M, Aldr

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 2.56 MB

english, 2015

8

Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter

Wang, Jing, Sun, Chongxiu, Gerdes, Norbert, Liu, Conglin, Liao, Mengyang, Liu, Jian, Shi, Michael A, He, Aina, Zhou, Yi, Sukhova, Galina K, Chen, Huimei, Cheng, Xian Wu, Kuzuya, Masafumi, Murohara, To

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.92 MB

english, 2015

9

Inhibition of amyloid-β plaque formation by α-synuclein

Bachhuber, Teresa, Katzmarski, Natalie, McCarter, Joanna F, Loreth, Desiree, Tahirovic, Sabina, Kamp, Frits, Abou-Ajram, Claudia, Nuscher, Brigitte, Serrano-Pozo, Alberto, Müller, Alexandra, Prinz, Ma

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 4.68 MB

english, 2015

10

Subclonal diversification of primary breast cancer revealed by multiregion sequencing

Yates, Lucy R, Gerstung, Moritz, Knappskog, Stian, Desmedt, Christine, Gundem, Gunes, Van Loo, Peter, Aas, Turid, Alexandrov, Ludmil B, Larsimont, Denis, Davies, Helen, Li, Yilong, Ju, Young Seok, Ram

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 4.17 MB

english, 2015

11

Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes

Xue, Ruidan, Lynes, Matthew D, Dreyfuss, Jonathan M, Shamsi, Farnaz, Schulz, Tim J, Zhang, Hongbin, Huang, Tian Lian, Townsend, Kristy L, Li, Yiming, Takahashi, Hirokazu, Weiner, Lauren S, White, Andr

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 2.08 MB

english, 2015

12

Innate lymphoid cells in the initiation, regulation and resolution of inflammation

Sonnenberg, Gregory F, Artis, David

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 2.53 MB

english, 2015

13

Inflammasomes: mechanism of action, role in disease, and therapeutics

Guo, Haitao, Callaway, Justin B, Ting, Jenny P-Y

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 2.10 MB

english, 2015

14

IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases

Teng, Michele W L, Bowman, Edward P, McElwee, Joshua J, Smyth, Mark J, Casanova, Jean-Laurent, Cooper, Andrea M, Cua, Daniel J

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2015

15

Heterogeneity of autoimmune diseases: pathophysiologic insights from genetics and implications for new therapies

Cho, Judy H, Feldman, Marc

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2015

16

The emerging role of resident memory T cells in protective immunity and inflammatory disease

Park, Chang Ook, Kupper, Thomas S

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.60 MB

english, 2015

17

Influence of nutrient-derived metabolites on lymphocyte immunity

Veldhoen, Marc, Ferreira, Cristina

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.92 MB

english, 2015

18

Shifts in macrophage cytokine production drive muscle fibrosis

Tidball, James G, Wehling-Henricks, Michelle

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 646 KB

english, 2015

19

Liquid biopsies reveal the dynamic nature of resistance mechanisms in solid tumors

Meador, Catherine B, Lovly, Christine M

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 683 KB

english, 2015

20

A gut feeling about immunity

Khamsi, Roxanne

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 2.31 MB

english, 2015

21

Almighty antibodies? A new wave of antibody-based approaches aims to combat HIV

Hayden, Erika Check

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 608 KB

english, 2015

22

Erratum: Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients

Siravegna, Giulia, Mussolin, Benedetta, Buscarino, Michela, Corti, Giorgio, Cassingena, Andrea, Crisafulli, Giovanni, Ponzetti, Agostino, Cremolini, Chiara, Amatu, Alessio, Lauricella, Calogero, Lamba

Journal:

Nature Medicine

Année:

2015

Fichier:

PDF, 103 KB

2015

23

Tracing human brown fat

Boon, Mariëtte R, Nascimento, Emmani B M, van Marken Lichtenbelt, Wouter D

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 859 KB

english, 2015

24

Big data meets mechanism

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 139 KB

english, 2015

25

To build better tuberculosis diagnostics, look for 'biosignatures'

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 113 KB

english, 2015

26

All aboard: Will molecular tumor boards help cancer patients?

Erdmann, Jeanne

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 392 KB

english, 2015

27

Biomedical briefing

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 407 KB

english, 2015