Volume 21; Issue 6

Main
Nature Medicine
Volume 21; Issue 6

Nature Medicine

Volume 21; Issue 6

1

Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity

Dalmas, Elise, Toubal, Amine, Alzaid, Fawaz, Blazek, Katrina, Eames, Hayley L, Lebozec, Kristell, Pini, Maria, Hainault, Isabelle, Montastier, Emilie, Denis, Raphaël G P, Ancel, Patricia, Lacombe, Amé

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.79 MB

english, 2015

2

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

Grasso, Catherine S, Tang, Yujie, Truffaux, Nathalene, Berlow, Noah E, Liu, Lining, Debily, Marie-Anne, Quist, Michael J, Davis, Lara E, Huang, Elaine C, Woo, Pamelyn J, Ponnuswami, Anitha, Chen, Spen

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2015

3

4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors

Long, Adrienne H, Haso, Waleed M, Shern, Jack F, Wanhainen, Kelsey M, Murgai, Meera, Ingaramo, Maria, Smith, Jillian P, Walker, Alec J, Kohler, M Eric, Venkateshwara, Vikas R, Kaplan, Rosandra N, Patt

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 2.80 MB

english, 2015

4

Acquired EGFR C797S mutation mediates resistance to AZD9291 in non–small cell lung cancer harboring EGFR T790M

Thress, Kenneth S, Paweletz, Cloud P, Felip, Enriqueta, Cho, Byoung Chul, Stetson, Daniel, Dougherty, Brian, Lai, Zhongwu, Markovets, Aleksandra, Vivancos, Ana, Kuang, Yanan, Ercan, Dalia, Matthews, S

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1019 KB

english, 2015

5

Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells

Pallett, Laura J, Gill, Upkar S, Quaglia, Alberto, Sinclair, Linda V, Jover-Cobos, Maria, Schurich, Anna, Singh, Kasha P, Thomas, Niclas, Das, Abhishek, Chen, Antony, Fusai, Giuseppe, Bertoletti, Anto

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.78 MB

english, 2015

6

Negative feedback–defective PRPS1 mutants drive thiopurine resistance in relapsed childhood ALL

Li, Benshang, Li, Hui, Bai, Yun, Kirschner-Schwabe, Renate, Yang, Jun J, Chen, Yao, Lu, Gang, Tzoneva, Gannie, Ma, Xiaotu, Wu, Tongmin, Li, Wenjing, Lu, Haisong, Ding, Lixia, Liang, Huanhuan, Huang, X

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 2.02 MB

english, 2015

7

Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models

Schiffer, Mario, Teng, Beina, Gu, Changkyu, Shchedrina, Valentina A, Kasaikina, Marina, Pham, Vincent A, Hanke, Nils, Rong, Song, Gueler, Faikah, Schroder, Patricia, Tossidou, Irini, Park, Joon-Keun,

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 3.88 MB

english, 2015

8

Common clonal origin of central and resident memory T cells following skin immunization

Gaide, Olivier, Emerson, Ryan O, Jiang, Xiaodong, Gulati, Nicholas, Nizza, Suzanne, Desmarais, Cindy, Robins, Harlan, Krueger, James G, Clark, Rachael A, Kupper, Thomas S

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.65 MB

english, 2015

9

KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis

Shankman, Laura S, Gomez, Delphine, Cherepanova, Olga A, Salmon, Morgan, Alencar, Gabriel F, Haskins, Ryan M, Swiatlowska, Pamela, Newman, Alexandra A C, Greene, Elizabeth S, Straub, Adam C, Isakson,

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 2.92 MB

english, 2015

10

The Cyclophilin A–CD147 complex promotes the proliferation and homing of multiple myeloma cells

Zhu, Di, Wang, Zhongqiu, Zhao, Jian-Jun, Calimeri, Teresa, Meng, Jiang, Hideshima, Teru, Fulciniti, Mariateresa, Kang, Yue, Ficarro, Scott B, Tai, Yu-Tzu, Hunter, Zachary, McMilin, Douglas, Tong, Haox

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 3.27 MB

english, 2015

11

Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α

Mascanfroni, Ivan D, Takenaka, Maisa C, Yeste, Ada, Patel, Bonny, Wu, Yan, Kenison, Jessica E, Siddiqui, Shafiuddin, Basso, Alexandre S, Otterbein, Leo E, Pardoll, Drew M, Pan, Fan, Priel, Avner, Clis

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.94 MB

english, 2015

12

The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes

Belgardt, Bengt-Frederik, Ahmed, Kashan, Spranger, Martina, Latreille, Mathieu, Denzler, Remy, Kondratiuk, Nadiia, von Meyenn, Ferdinand, Villena, Felipe Nunez, Herrmanns, Karolin, Bosco, Domenico, Ke

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.95 MB

english, 2015

13

New consent requirements for newborn screening raise concerns

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 202 KB

english, 2015

14

Regulation of immunopathology in hepatitis B virus infection

Piconese, Silvia, Barnaba, Vincenzo

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 473 KB

english, 2015

15

Unpleasant memories: tissue-embedded T cell memory drives skin hypersensitivity

Gebhardt, Thomas, Carbone, Francis R

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 548 KB

english, 2015

16

Converting smooth muscle cells to macrophage-like cells with KLF4 in atherosclerotic plaques

Rosenfeld, Michael E

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 641 KB

english, 2015

17

Mutant PRPS1: a new therapeutic target in relapsed acute lymphoblastic leukemia

Mullighan, Charles G

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 386 KB

english, 2015

18

Updated, augmented vaccines compete with original antigenic sin

Chakradhar, Shraddha

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2015

19

Binding time—not just affinity—gains stature in drug design

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 454 KB

english, 2015

20

Microbiome models, on computers and in lab dishes, see progress

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 964 KB

english, 2015

21

Biomedical briefing

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 934 KB

english, 2015

22

Let research bloom

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 139 KB

english, 2015