Volume 21; Issue 2

Main
Nature Medicine
Volume 21; Issue 2

Nature Medicine

Volume 21; Issue 2

1

Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis

Crane, Justin D, Palanivel, Rengasamy, Mottillo, Emilio P, Bujak, Adam L, Wang, Huaqing, Ford, Rebecca J, Collins, Andrew, Blümer, Regje M, Fullerton, Morgan D, Yabut, Julian M, Kim, Janice J, Ghia, J

Journal:

Nature Medicine

Année:

2014

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2014

2

Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance

Fang, Sungsoon, Suh, Jae Myoung, Reilly, Shannon M, Yu, Elizabeth, Osborn, Olivia, Lackey, Denise, Yoshihara, Eiji, Perino, Alessia, Jacinto, Sandra, Lukasheva, Yelizaveta, Atkins, Annette R, Khvat, A

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2015

3

Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis

Palumbo-Zerr, Katrin, Zerr, Pawel, Distler, Alfiya, Fliehr, Judith, Mancuso, Rossella, Huang, Jingang, Mielenz, Dirk, Tomcik, Michal, Fürnrohr, Barbara G, Scholtysek, Carina, Dees, Clara, Beyer, Chris

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 2.93 MB

english, 2015

4

Myeloid-derived growth factor (C19orf10) mediates cardiac repair following myocardial infarction

Korf-Klingebiel, Mortimer, Reboll, Marc R, Klede, Stefanie, Brod, Torben, Pich, Andreas, Polten, Felix, Napp, L Christian, Bauersachs, Johann, Ganser, Arnold, Brinkmann, Eva, Reimann, Ines, Kempf, Tib

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 5.88 MB

english, 2015

5

Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes

Tang, Cong, Ahmed, Kashan, Gille, Andreas, Lu, Shun, Gröne, Hermann-Josef, Tunaru, Sorin, Offermanns, Stefan

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 752 KB

english, 2015

6

Structure-inherent targeting of near-infrared fluorophores for parathyroid and thyroid gland imaging

Hyun, Hoon, Park, Min Ho, Owens, Eric A, Wada, Hideyuki, Henary, Maged, Handgraaf, Henricus J M, Vahrmeijer, Alexander L, Frangioni, John V, Choi, Hak Soo

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 3.19 MB

english, 2015

7

B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers

Fukazawa, Yoshinori, Lum, Richard, Okoye, Afam A, Park, Haesun, Matsuda, Kenta, Bae, Jin Young, Hagen, Shoko I, Shoemaker, Rebecca, Deleage, Claire, Lucero, Carissa, Morcock, David, Swanson, Tonya, Le

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 2.81 MB

english, 2015

8

Isocitrate dehydrogenase 1 and 2 mutations induce BCL-2 dependence in acute myeloid leukemia

Chan, Steven M, Thomas, Daniel, Corces-Zimmerman, M Ryan, Xavy, Seethu, Rastogi, Suchita, Hong, Wan-Jen, Zhao, Feifei, Medeiros, Bruno C, Tyvoll, David A, Majeti, Ravindra

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2015

9

Whole-genome sequencing of quartet families with autism spectrum disorder

Yuen, Ryan K C, Thiruvahindrapuram, Bhooma, Merico, Daniele, Walker, Susan, Tammimies, Kristiina, Hoang, Ny, Chrysler, Christina, Nalpathamkalam, Thomas, Pellecchia, Giovanna, Liu, Yi, Gazzellone, Mat

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 843 KB

english, 2015

10

A synthetic lethal approach targeting mutant isocitrate dehydrogenase in acute myeloid leukemia

Verma, Amit, Steidl, Ulrich

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 327 KB

english, 2015

11

AIDS virus seeks refuge in B cell follicles

Streeck, Hendrik

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.94 MB

english, 2015

12

Reducing peripheral serotonin turns up the heat in brown fat

Carey, Andrew L, Kingwell, Bronwyn A

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 989 KB

english, 2015

13

Understanding Local Macrophage Phenotypes In Disease: Shape-shifting macrophages

Liddiard, Kate, Taylor, Philip R

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 464 KB

english, 2015

14

Understanding Local Macrophage Phenotypes In Disease: Modulating macrophage function to treat cancer

Bronte, Vincenzo, Murray, Peter J

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2015

15

Therapeutic genome editing: prospects and challenges

Cox, David Benjamin Turitz, Platt, Randall Jeffrey, Zhang, Feng

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.86 MB

english, 2015

16

Regulators move toward adverse event reporting via mobile apps

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 259 KB

english, 2015

17

Biosimilar makers flout forced patent negotiations in US

Willyard, Cassandra

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 546 KB

english, 2015

18

The future of cancer genomics

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 129 KB

english, 2015

19

Response to Burgess

Befroy, Douglas E, Kibbey, Richard G, Perry, Rachel J, Petersen, Kitt Falk, Rothman, Douglas L, Shulman, Gerald I

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 380 KB

english, 2015

20

Biomedical briefing

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2015

21

Approval may embolden industry to combine cancer therapies

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 256 KB

english, 2015

22

Limitations of detection of anaplerosis and pyruvate cycling from metabolism of [1-13C] acetate

Burgess, Shawn C, Merritt, Mathew E, Jones, John G, Browning, Jeffrey D, Sherry, A Dean, Malloy, Craig R

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 352 KB

english, 2015

23

In new crowdfunding trend, donors decide fate of clinical trials

Chakradhar, Shraddha

Journal:

Nature Medicine

Année:

2015

Fichier:

PDF, 5 KB

2015