Volume 19; Issue 2

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Nature Medicine
Volume 19; Issue 2

Nature Medicine

Volume 19; Issue 2

1

Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance

Liew, Chong Wee, Boucher, Jeremie, Cheong, Jit Kong, Vernochet, Cecile, Koh, Ho-Jin, Mallol, Cristina, Townsend, Kristy, Langin, Dominique, Kawamori, Dan, Hu, Jiang, Tseng, Yu-Hua, Hellerstein, Marc K

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.55 MB

english, 2013

2

The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity

Collison, Adam, Hatchwell, Luke, Verrills, Nicole, Wark, Peter A B, de Siqueira, Ana Pereira, Tooze, Melinda, Carpenter, Helen, Don, Anthony S, Morris, Jonathan C, Zimmermann, Nives, Bartlett, Nathan

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 857 KB

english, 2013

3

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

Souers, Andrew J, Leverson, Joel D, Boghaert, Erwin R, Ackler, Scott L, Catron, Nathaniel D, Chen, Jun, Dayton, Brian D, Ding, Hong, Enschede, Sari H, Fairbrother, Wayne J, Huang, David C S, Hymowitz,

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2013

4

Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma

Chen, Leilei, Li, Yan, Lin, Chi Ho, Chan, Tim Hon Man, Chow, Raymond Kwok Kei, Song, Yangyang, Liu, Ming, Yuan, Yun-Fei, Fu, Li, Kong, Kar Lok, Qi, Lihua, Li, Yan, Zhang, Na, Tong, Amy Hin Yan, Kwong,

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 2.25 MB

english, 2013

5

Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy

Luxán, Guillermo, Casanova, Jesús C, Martínez-Poveda, Beatriz, Prados, Belén, D'Amato, Gaetano, MacGrogan, Donal, Gonzalez-Rajal, Alvaro, Dobarro, David, Torroja, Carlos, Martinez, Fernando, Izquierdo

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 2.21 MB

english, 2013

6

WNT signaling in bone homeostasis and disease: from human mutations to treatments

Baron, Roland, Kneissel, Michaela

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 2.27 MB

english, 2013

7

Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis

LeBleu, Valerie S, Teng, Yingqi, O'Connell, Joyce T, Charytan, David, Müller, Gerhard A, Müller, Claudia A, Sugimoto, Hikaru, Kalluri, Raghu

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2013

8

Weighing in on autoimmune disease: Big data tip the scale

Dendrou, Calliope A, Bell, John I, Fugger, Lars

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 292 KB

english, 2013

9

Harnessing CD4+ T cell responses in HIV vaccine development

Streeck, Hendrik, D'Souza, M Patricia, Littman, Dan R, Crotty, Shane

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 594 KB

english, 2013

10

Malaria biology and disease pathogenesis: insights for new treatments

Miller, Louis H, Ackerman, Hans C, Su, Xin-zhuan, Wellems, Thomas E

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.60 MB

english, 2013

11

Public health challenges and prospects for malaria control and elimination

Alonso, Pedro L, Tanner, Marcel

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 931 KB

english, 2013

12

Immune mechanisms in malaria: new insights in vaccine development

Riley, Eleanor M, Stewart, V Ann

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 5.75 MB

english, 2013

13

Compacting the heart with Notch

Misra, Chaitali, Garg, Vidu

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 3.86 MB

english, 2013

14

A long pause

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 106 KB

english, 2013

15

Ahead of WHO meeting, experts clash over tuberculosis targets

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 615 KB

english, 2013

16

Diagnostic lens turns to difficult-to-detect ovarian cancer

Azvolinsky, Anna

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 92 KB

english, 2013

17

Animal rule for drug approval creates a jungle of confusion

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 447 KB

english, 2013

18

Cancer: Exosomes from the stroma

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 168 KB

english, 2013

19

Apoptosis therapy: driving cancers down the road to ruin

Green, Douglas R., Walczak, Henning

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 785 KB

english, 2013

20

Amgen deal triggers watchful waiting in targeted nanomedicine

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 715 KB

english, 2013

21

The Sticking Point

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 892 KB

english, 2013

22

Tethered capsule endomicroscopy enables less invasive imaging of gastrointestinal tract microstructure

Gora, Michalina J, Sauk, Jenny S, Carruth, Robert W, Gallagher, Kevin A, Suter, Melissa J, Nishioka, Norman S, Kava, Lauren E, Rosenberg, Mireille, Bouma, Brett E, Tearney, Guillermo J

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 914 KB

english, 2013

23

RNA editing enters the limelight in cancer

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 519 KB

english, 2013

24

Weighing In On Autoimmune Disease: 'Hub-and-spoke' T cell traffic in autoimmunity

Steinman, Lawrence

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.76 MB

english, 2013

25

Near-record number of approvals signals drug development shift

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 292 KB

english, 2013

26

Developing countries can contribute to global health innovation

Chakma, Justin, Chakma, Hiroshi

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 94 KB

english, 2013

27

Corrections

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 392 KB

english, 2013

28

Stapled peptide to enter human testing, but affinity questions remain

Grigoryev, Yevgeniy

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 96 KB

english, 2013

29

Imaging local neuronal activity by monitoring PO2 transients in capillaries

Parpaleix, Alexandre, Houssen, Yannick Goulam, Charpak, Serge

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2013

30

First 'breakthrough' drugs designated, but dilution worries linger

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 142 KB

english, 2013

31

Metabolism: IL-13 controls blood sugar

López, Juan Carlos

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 169 KB

english, 2013

32

Pain: Painful communication

Chmielnicki, Eva

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 168 KB

english, 2013

33

Stem cells: Promoting pluripotency

Da Silva, Kevin

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 169 KB

english, 2013

34

The clot thickens for long-lasting drugs that stop hemophilia short

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 249 KB

english, 2013

35

Exploring the epigenetics of cocaine resistance

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 142 KB

english, 2013

36

Straight talk with...Dalvir Gill

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 413 KB

english, 2013

37

Biomedical briefing

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 601 KB

english, 2013

38

Money without collaboration won't bring cures

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 132 KB

english, 2013

39

A history of opposing reform

Campbell, Eric G.

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 173 KB

english, 2013