Volume 19; Issue 11

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Nature Medicine
Volume 19; Issue 11

Nature Medicine

Volume 19; Issue 11

1

Coordinate activation of Shh and PI3K signaling in PTEN-deficient glioblastoma: new therapeutic opportunities

Gruber Filbin, Mariella, Dabral, Sukriti K, Pazyra-Murphy, Maria F, Ramkissoon, Shakti, Kung, Andrew L, Pak, Ekaterina, Chung, Jarom, Theisen, Matthew A, Sun, Yanping, Franchetti, Yoko, Sun, Yu, Shulm

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2013

2

Chloride extrusion enhancers as novel therapeutics for neurological diseases

Gagnon, Martin, Bergeron, Marc J, Lavertu, Guillaume, Castonguay, Annie, Tripathy, Sasmita, Bonin, Robert P, Perez-Sanchez, Jimena, Boudreau, Dominic, Wang, Bin, Dumas, Lionel, Valade, Isabelle, Bacha

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2013

3

Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis

Qiang, Xiaoling, Yang, Weng-Lang, Wu, Rongqian, Zhou, Mian, Jacob, Asha, Dong, Weifeng, Kuncewitch, Michael, Ji, Youxin, Yang, Huan, Wang, Haichao, Fujita, Jun, Nicastro, Jeffrey, Coppa, Gene F, Trace

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 843 KB

english, 2013

4

High-throughput identification of antigen-specific TCRs by TCR gene capture

Linnemann, Carsten, Heemskerk, Bianca, Kvistborg, Pia, Kluin, Roelof J C, Bolotin, Dmitriy A, Chen, Xiaojing, Bresser, Kaspar, Nieuwland, Marja, Schotte, Remko, Michels, Samira, Gomez-Eerland, Raquel,

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 11.33 MB

english, 2013

5

Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer

Vaishnavi, Aria, Capelletti, Marzia, Le, Anh T, Kako, Severine, Butaney, Mohit, Ercan, Dalia, Mahale, Sakshi, Davies, Kurtis D, Aisner, Dara L, Pilling, Amanda B, Berge, Eamon M, Kim, Jhingook, Sasaki

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 669 KB

english, 2013

6

Loss of immune escape mutations during persistent HCV infection in pregnancy enhances replication of vertically transmitted viruses

Honegger, Jonathan R, Kim, Seungtaek, Price, Aryn A, Kohout, Jennifer A, McKnight, Kevin L, Prasad, Mona R, Lemon, Stanley M, Grakoui, Arash, Walker, Christopher M

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 794 KB

english, 2013

7

Differential regulation of myeloid leukemias by the bone marrow microenvironment

Krause, Daniela S, Fulzele, Keertik, Catic, André, Sun, Chia Chi, Dombkowski, David, Hurley, Michael P, Lezeau, Sanon, Attar, Eyal, Wu, Joy Y, Lin, Herbert Y, Divieti-Pajevic, Paola, Hasserjian, Rober

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 977 KB

english, 2013

8

A new cloning and expression system yields and validates TCRs from blood lymphocytes of patients with cancer within 10 days

Kobayashi, Eiji, Mizukoshi, Eishiro, Kishi, Hiroyuki, Ozawa, Tatsuhiko, Hamana, Hiroshi, Nagai, Terumi, Nakagawa, Hidetoshi, Jin, Aishun, Kaneko, Shuichi, Muraguchi, Atsushi

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2013

9

Microenvironmental regulation of tumor progression and metastasis

Quail, Daniela F, Joyce, Johanna A

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 19.88 MB

english, 2013

10

Tumor adaptation and resistance to RAF inhibitors

Lito, Piro, Rosen, Neal, Solit, David B

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 3.58 MB

english, 2013

11

Straight talk with...Ricardo Dolmetsch

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 442 KB

english, 2013

12

Stem cells: A reprogrammable rodent

Da Silva, Kevin

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 290 KB

english, 2013

13

Neurodevelopmental disorders: Microcephaly mutations

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 290 KB

english, 2013

14

Trial designs advance to overcome bitter pill of placebo effect

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1002 KB

english, 2013

15

Tumor metastasis: moving new biological insights into the clinic

Wan, Liling, Pantel, Klaus, Kang, Yibin

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 18.39 MB

english, 2013

16

The epigenetics of epithelial-mesenchymal plasticity in cancer

Tam, Wai Leong, Weinberg, Robert A

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2013

17

Mst-1 switches between cardiac cell life and death

Dhingra, Rimpy, Kirshenbaum, Lorrie A

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2013

18

Pharmacogenetic tests yield bonus benefit: better drug adherence

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 502 KB

english, 2013

19

Mechanisms of resistance to therapies targeting BRCA-mutant cancers

Lord, Christopher J, Ashworth, Alan

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2013

20

Unraveling the therapeutic potential of the Hedgehog pathway in cancer

Amakye, Dereck, Jagani, Zainab, Dorsch, Marion

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2013

21

The quest to overcome resistance to EGFR-targeted therapies in cancer

Chong, Curtis R, Jänne, Pasi A

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2013

22

Eugenics to medical genetics

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 141 KB

english, 2013

23

Small nanobody drugs win big backing from pharma

Williams, Sarah CP

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 493 KB

english, 2013

24

Sirt1–Claudin-1 crosstalk regulates renal function

Nihalani, Deepak, Susztak, Katalin

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 726 KB

english, 2013

25

Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes

Hasegawa, Kazuhiro, Wakino, Shu, Simic, Petra, Sakamaki, Yusuke, Minakuchi, Hitoshi, Fujimura, Keiko, Hosoya, Kozi, Komatsu, Motoaki, Kaneko, Yuka, Kanda, Takeshi, Kubota, Eiji, Tokuyama, Hirobumi, Ha

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 2.03 MB

english, 2013

26

Activation of Hedgehog signaling by loss of GNAS causes heterotopic ossification

Regard, Jean B, Malhotra, Deepti, Gvozdenovic-Jeremic, Jelena, Josey, Michelle, Chen, Min, Weinstein, Lee S, Lu, Jianming, Shore, Eileen M, Kaplan, Frederick S, Yang, Yingzi

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.90 MB

english, 2013

27

Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2

Maejima, Yasuhiro, Kyoi, Shiori, Zhai, Peiyong, Liu, Tong, Li, Hong, Ivessa, Andreas, Sciarretta, Sebastiano, Del Re, Dominic P, Zablocki, Daniela K, Hsu, Chiao-Po, Lim, Dae-Sik, Isobe, Mitsuaki, Sado

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 2.43 MB

english, 2013

28

Telltale hearts

Erdmann, Jeanne

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2013

29

Keeping pace with cancer

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 98 KB

english, 2013

30

An endogenous factor mediates shock-induced injury

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 273 KB

english, 2013

31

Cancer immunotherapy advances spawn calls for new endpoints

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 193 KB

english, 2013

32

Striking a balance in fragile X

Smith, Laura N, Cowan, Christopher W

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 261 KB

english, 2013

33

License with care

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 104 KB

english, 2013

34

Cancer: Liver cancer progenitors

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 290 KB

english, 2013

35

Slimming down via the microbiota

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 420 KB

english, 2013

36

Immunology: Mucous-mediated tolerance

Farrell, Alison

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 290 KB

english, 2013

37

A new value proposition

Kolodziej, Michael, Klein, Ira, Reisman, Lonny

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 167 KB

english, 2013

38

Sun sets on protein initiative, casting shadow over drug discovery

Devitt, Elizabeth

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 378 KB

english, 2013

39

Genetic and acute CPEB1 depletion ameliorate fragile X pathophysiology

Udagawa, Tsuyoshi, Farny, Natalie G, Jakovcevski, Mira, Kaphzan, Hanoch, Alarcon, Juan Marcos, Anilkumar, Shobha, Ivshina, Maria, Hurt, Jessica A, Nagaoka, Kentaro, Nalavadi, Vijayalaxmi C, Lorenz, Lo

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 762 KB

english, 2013

40

Biomedical briefing

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 540 KB

english, 2013