Volume 18; Issue 2

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Nature Medicine
Volume 18; Issue 2

Nature Medicine

Volume 18; Issue 2

1

Harnessing evolutionary biology to combat infectious disease

Little, Tom J, Allen, Judith E, Babayan, Simon A, Matthews, Keith R, Colegrave, Nick

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 405 KB

english, 2012

2

Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia

Ntziachristos, Panagiotis, Tsirigos, Aristotelis, Vlierberghe, Pieter Van, Nedjic, Jelena, Trimarchi, Thomas, Flaherty, Maria Sol, Ferres-Marco, Dolors, da Ros, Vanina, Tang, Zuojian, Siegle, Jasmin

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 16.76 MB

english, 2012

3

An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection

Chen, Fei, Liu, Zhugong, Wu, Wenhui, Rozo, Cristina, Bowdridge, Scott, Millman, Ariel, Van Rooijen, Nico, Urban, Joseph F, Wynn, Thomas A, Gause, William C

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 962 KB

english, 2012

4

A delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapy

Zhang, Ge, Guo, Baosheng, Wu, Heng, Tang, Tao, Zhang, Bao-Ting, Zheng, Lizhen, He, Yixin, Yang, Zhijun, Pan, Xiaohua, Chow, Heelum

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.77 MB

english, 2012

5

Identification of a mutation in the extracellular domain of the Epidermal Growth Factor Receptor conferring cetuximab resistance in colorectal cancer

Montagut, Clara, Dalmases, Alba, Bellosillo, Beatriz, Crespo, Marta, Pairet, Silvia, Iglesias, Mar, Salido, Marta, Gallen, Manuel, Marsters, Scot, Tsai, Siao Ping

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 529 KB

english, 2012

6

Magnetic resonance imaging of glutamate

Cai, Kejia, Haris, Mohammad, Singh, Anup, Kogan, Feliks, Greenberg, Joel H, Hariharan, Hari, Detre, John A, Reddy, Ravinder

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2012

7

AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation

Lanner, Johanna T, Georgiou, Dimitra K, Dagnino-Acosta, Adan, Ainbinder, Alina, Cheng, Qing, Joshi, Aditya D, Chen, Zanwen, Yarotskyy, Viktor, Oakes, Joshua M, Lee, Chang Seok, Monroe, Tanner O, Santi

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2012

8

Molecular imaging using fluorescent lectins permits rapid endoscopic identification of dysplasia in Barrett's esophagus

Bird-Lieberman, Elizabeth L, Neves, André A, Lao-Sirieix, Pierre, O'Donovan, Maria, Novelli, Marco, Lovat, Laurence B, Eng, William S, Mahal, Lara K, Brindle, Kevin M, Fitzgerald, Rebecca C

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2012

9

A delicate balance: tweaking IL-2 immunotherapy

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 190 KB

english, 2012

10

The road to resistance: EGFR mutation and cetuximab

Bardelli, Alberto, Jänne, Pasi A

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 548 KB

english, 2012

11

Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export

Lei, Peng, Ayton, Scott, Finkelstein, David I, Spoerri, Loredana, Ciccotosto, Giuseppe D, Wright, David K, Wong, Bruce X W, Adlard, Paul A, Cherny, Robert A, Lam, Linh Q, Roberts, Blaine R, Volitakis,

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 879 KB

english, 2012

12

Puzzling over schizophrenia: Schizophrenia as a pathway disease

Sullivan, Patrick F

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 389 KB

english, 2012

13

cGMP-Prkg1 signaling and Pde5 inhibition shelter cochlear hair cells and hearing function

Jaumann, Mirko, Dettling, Juliane, Gubelt, Martin, Zimmermann, Ulrike, Gerling, Andrea, Paquet-Durand, François, Feil, Susanne, Wolpert, Stephan, Franz, Christoph, Varakina, Ksenya, Xiong, Hao, Brandt

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.44 MB

english, 2012

14

CD4+ T cells limit the damage in influenza

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 889 KB

english, 2012

15

A tumor suppressor function of Smurf2 associated with controlling chromatin landscape and genome stability through RNF20

Blank, Michael, Tang, Yi, Yamashita, Motozo, Burkett, Sandra S, Cheng, Steven Y, Zhang, Ying E

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 2.71 MB

english, 2012

16

Identification of the Niemann-Pick C1–like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor

Sainz, Bruno, Barretto, Naina, Martin, Danyelle N, Hiraga, Nobuhiko, Imamura, Michio, Hussain, Snawar, Marsh, Katherine A, Yu, Xuemei, Chayama, Kazuaki, Alrefai, Waddah A, Uprichard, Susan L

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 733 KB

english, 2012

17

MicroRNA-21 targets the vitamin D–dependent antimicrobial pathway in leprosy

Liu, Philip T, Wheelwright, Matthew, Teles, Rosane, Komisopoulou, Evangelia, Edfeldt, Kristina, Ferguson, Benjamin, Mehta, Manali D, Vazirnia, Aria, Rea, Thomas H, Sarno, Euzenir N, Graeber, Thomas G,

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2012

18

Puzzling over schizophrenia: Schizophrenia, social environment and the brain

Tost, Heike, Meyer-Lindenberg, Andreas

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 570 KB

english, 2012

19

Clinicians call for greater transparency in trial recruitment

Hersher, Rebecca

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 108 KB

english, 2012

20

New insight on bariatric surgery difficult to swallow

Moyer, Melinda Wenner

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 126 KB

english, 2012

21

Prostaglandin E2 promotes intestinal tumor growth via DNA methylation

Xia, Dianren, Wang, Dingzhi, Kim, Sun-Hee, Katoh, Hiroshi, DuBois, Raymond N

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 403 KB

english, 2012

22

Straight talk with...Patrick Soon-Shiong

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 185 KB

english, 2012

23

Brain: Anxious about your meal?

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 170 KB

english, 2012

24

Biomedical briefing

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 278 KB

english, 2012

25

Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans

Wilkinson, Tom M, Li, Chris K F, Chui, Cecilia S C, Huang, Arthur K Y, Perkins, Molly, Liebner, Julia C, Lambkin-Williams, Rob, Gilbert, Anthony, Oxford, John, Nicholas, Ben, Staples, Karl J, Dong, Ta

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 955 KB

english, 2012

26

Cancer-fighting Smurf

Wang, Xi, Roberts, Charles W M

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 642 KB

english, 2012

27

Smallpox: the big picture

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 150 KB

english, 2012

28

Fifth time's the charm?

Hersher, Rebecca

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 108 KB

english, 2012

29

Science in times of crisis

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 84 KB

english, 2012

30

Obesity: Is beige the new brown?

Levinson, Randy

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 170 KB

english, 2012

31

An unheard benefit of Cialis

Layman, Wanda, Zuo, Jian

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 500 KB

english, 2012

32

Spain reeling from budget and staff cuts in biomedicine

Catanzaro, Michele

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 126 KB

english, 2012

33

Action is required to safeguard the future of academic medicine in the UK

Funston, Garth M, Young, Adam M H

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 156 KB

english, 2012

34

With bated breath, companies await approval for inhalable drugs

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 116 KB

english, 2012

35

Antimicrobials: Mycobacterial asymmetry

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 170 KB

english, 2012

36

Cidea is an essential transcriptional coactivator regulating mammary gland secretion of milk lipids

Wang, Wenshan, Lv, Na, Zhang, Shasha, Shui, Guanghou, Qian, Hui, Zhang, Jingfeng, Chen, Yuanying, Ye, Jing, Xie, Yuansheng, Shen, Yuemao, Wenk, Markus R, Li, Peng

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2012

37

Ironing out tau's role in parkinsonism

Stankowski, Jeannette N, Dawson, Valina L, Dawson, Ted M

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 2.34 MB

english, 2012

38

India mulling stricter laws to curb unethical trials

Jayaraman, Killugudi

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 188 KB

english, 2012

39

Inflammation: Burning up the brain

Da Silva, Kevin

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 170 KB

english, 2012

40

Building bones by knocking down genes

Rosen, Clifford J

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 2.59 MB

english, 2012

41

The Ultimate Endpoint

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 417 KB

english, 2012

42

Internet data miners strike disease detection gold

Hersher, Rebecca

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 192 KB

english, 2012

43

Correction

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 161 KB

english, 2012

44

Single atom substitution in mouse protein kinase G eliminates oxidant sensing to cause hypertension

Prysyazhna, Oleksandra, Rudyk, Olena, Eaton, Philip

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 886 KB

english, 2012

45

Congress vouches for priority review of childhood disease

Palmer, Roxanne

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 250 KB

english, 2012