Volume 18; Issue 10

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Nature Medicine
Volume 18; Issue 10

Nature Medicine

Volume 18; Issue 10

1

MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity

Kusminski, Christine M, Holland, William L, Sun, Kai, Park, Jiyoung, Spurgin, Stephen B, Lin, Ying, Askew, G Roger, Simcox, Judith A, McClain, Don A, Li, Cai, Scherer, Philipp E

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.61 MB

english, 2012

2

Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function

Yoshioka, Kazuaki, Yoshida, Kotaro, Cui, Hong, Wakayama, Tomohiko, Takuwa, Noriko, Okamoto, Yasuo, Du, Wa, Qi, Xun, Asanuma, Ken, Sugihara, Kazushi, Aki, Sho, Miyazawa, Hidekazu, Biswas, Kuntal, Nagak

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 4.63 MB

english, 2012

3

In vivo photodynamic therapy using upconversion nanoparticles as remote-controlled nanotransducers

Idris, Niagara Muhammad, Gnanasammandhan, Muthu Kumara, Zhang, Jing, Ho, Paul C, Mahendran, Ratha, Zhang, Yong

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2012

4

Paradigm shifts in science: insights from the arts

Goldstein, Joseph L

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.58 MB

english, 2012

5

LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker

Chen, Dahu, Sun, Yutong, Wei, Yongkun, Zhang, Peijing, Rezaeian, Abdol Hossein, Teruya-Feldstein, Julie, Gupta, Sumeet, Liang, Han, Lin, Hui-Kuan, Hung, Mien-Chie, Ma, Li

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.56 MB

english, 2012

6

Repeat after me

Muñoz-Gil, Jorge, Marín-Espinoza, Gedio, Andrade-Vigo, José, Zavala, Roseline, Mata, Astolfo

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 3.78 MB

english, 2012

7

Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity

Li, Guangjin, Yu, Mingcan, Lee, Won-Woo, Tsang, Michael, Krishnan, Eswar, Weyand, Cornelia M, Goronzy, Jörg J

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2012

8

Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals

Bal, Naresh C, Maurya, Santosh K, Sopariwala, Danesh H, Sahoo, Sanjaya K, Gupta, Subash C, Shaikh, Sana A, Pant, Meghna, Rowland, Leslie A, Goonasekera, Sanjeewa A, Molkentin, Jeffery D, Periasamy, Mu

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2012

9

Diabetes: Dedifferentiation, not death

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 296 KB

english, 2012

10

Following nature's challenges

Sheetz, Michael P, Kenan, William R.

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 737 KB

english, 2012

11

The new drug circuit

Grushkin, Daniel

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2012

12

LIF-ting Hippo averts metastasis

Piccolo, Stefano

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 836 KB

english, 2012

13

The Ongoing Battle Against Influenza: The challenge of flu transmission

Lakdawala, Seema S, Subbarao, Kanta

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1001 KB

english, 2012

14

Early infection with respiratory syncytial virus impairs regulatory T cell function and increases susceptibility to allergic asthma

Krishnamoorthy, Nandini, Khare, Anupriya, Oriss, Timothy B, Raundhal, Mahesh, Morse, Christina, Yarlagadda, Manohar, Wenzel, Sally E, Moore, Martin L, Peebles, R Stokes, Ray, Anuradha, Ray, Prabir

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2012

15

A bispecific antibody to factors IXa and X restores factor VIII hemostatic activity in a hemophilia A model

Kitazawa, Takehisa, Igawa, Tomoyuki, Sampei, Zenjiro, Muto, Atsushi, Kojima, Tetsuo, Soeda, Tetsuhiro, Yoshihashi, Kazutaka, Okuyama-Nishida, Yukiko, Saito, Hiroyuki, Tsunoda, Hiroyuki, Suzuki, Tsukas

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 670 KB

english, 2012

16

Hantavirus treatments advance amidst outbreak in US park

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 75 KB

english, 2012

17

Heat from calcium cycling melts fat

Kozak, Leslie P, Young, Martin E

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 511 KB

english, 2012

18

On the road from classical to modern molecular biology

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2012

19

How lucky can one be? A perspective from a young scientist at the right place at the right time

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 367 KB

english, 2012

20

One path to understanding energy transduction in biological systems

Spudich, James A

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 2.24 MB

english, 2012

21

The Ongoing Battle Against Influenza: Drug-resistant influenza viruses: why fitness matters

Kelso, Anne, Hurt, Aeron C

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 3.78 MB

english, 2012

22

Naratriptan mitigates CGRP1-associated motor neuron degeneration caused by an expanded polyglutamine repeat tract

Minamiyama, Makoto, Katsuno, Masahisa, Adachi, Hiroaki, Doi, Hideki, Kondo, Naohide, Iida, Madoka, Ishigaki, Shinsuke, Fujioka, Yusuke, Matsumoto, Shinjiro, Miyazaki, Yu, Tanaka, Fumiaki, Kurihara, Hi

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2012

23

Companies wager high on CD38-targeting drugs for blood cancer

Hersher, Rebecca

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 68 KB

english, 2012

24

Lethal H5N1 influenza viruses are not resistant to interferon action in human, simian, porcine or chicken cells

Ngunjiri, John M, Mohni, Kareem N, Sekellick, Margaret J, Schultz-Cherry, Stacey, Webster, Robert G, Marcus, Philip I

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 485 KB

english, 2012

25

US presidential candidates diverge on how to help biopharma

Matthews, Susan

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 325 KB

english, 2012

26

Attacking the flank: targeting new pathways in SBMA

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.66 MB

english, 2012

27

“It can't be done”

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2012

28

Correction

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 75 KB

english, 2012

29

Proposal for San Francisco to negotiate drug prices makes waves

Raven, Kathleen

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 65 KB

english, 2012

30

Developmental biology using purified genes

Brown, Donald D

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 755 KB

english, 2012

31

Despite quintuple disappointments, Lilly still charms investors

Raven, Kathleen

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 68 KB

english, 2012

32

Straight talk with...Mary Woolley

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 394 KB

english, 2012

33

Editorial note: Lethal H5N1 influenza viruses escape host antiviral cytokine responses

Seo, Sang Heui, Hoffmann, Erich, Webster, Robert G

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 66 KB

english, 2012

34

Multigenerational epigenetic adaptation of the hepatic wound-healing response

Zeybel, Müjdat, Hardy, Timothy, Wong, Yi K, Mathers, John C, Fox, Christopher R, Gackowska, Agata, Oakley, Fiona, Burt, Alastair D, Wilson, Caroline L, Anstee, Quentin M, Barter, Matt J, Masson, Steve

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 67 KB

english, 2012

35

Annotating MYC status with 89Zr-transferrin imaging

Holland, Jason P, Evans, Michael J, Rice, Samuel L, Wongvipat, John, Sawyers, Charles L, Lewis, Jason S

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 894 KB

english, 2012

36

Early-stage therapies target surgery-induced erectile dysfunction

Williams, Sarah C P

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 409 KB

english, 2012

37

Immunology: Commensals under attack

Da Silva, Kevin

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 296 KB

english, 2012

38

Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF–triggered granulopoiesis

Skokowa, Julia, Klimiankou, Maxim, Klimenkova, Olga, Lan, Dan, Gupta, Kshama, Hussein, Kais, Carrizosa, Esteban, Kusnetsova, Inna, Li, Zhixiong, Sustmann, Claudio, Ganser, Arnold, Zeidler, Cornelia, K

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2012

39

NCATS gains first chief and positions for industry partnerships

Matthews, Susan

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 65 KB

english, 2012

40

Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor–γ agonists

Shimono, Kengo, Tung, Wei-en, Macolino, Christine, Chi, Amber Hsu-Tsai, Didizian, Johanna H, Mundy, Christina, Chandraratna, Roshantha A, Mishina, Yuji, Enomoto-Iwamoto, Motomi, Pacifici, Maurizio, Iw

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 67 KB

english, 2012

41

Disappearing disease

Blount, Stephen B

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 101 KB

english, 2012

42

The long reach of liver transplantation

Starzl, Thomas E

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 3.48 MB

english, 2012

43

Parsing the potential of a new male contraceptive

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 278 KB

english, 2012

44

Bioengingeering bacteria for a cure—it's not that easy

Grushkin, Daniel

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 232 KB

english, 2012

45

Biomedical briefing

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2012

46

Neurodegeneration: A translational block

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 296 KB

english, 2012

47

Cancer: Finding fusions

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 296 KB

english, 2012

48

Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma

Kwong, Lawrence N, Costello, James C, Liu, Huiyun, Jiang, Shan, Helms, Timothy L, Langsdorf, Aliete E, Jakubosky, David, Genovese, Giannicola, Muller, Florian L, Jeong, Joseph H, Bender, Ryan P, Chu,

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 9.42 MB

english, 2012

49

A complex substitute: antibody therapy for hemophilia

Lillicrap, David

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 20.50 MB

english, 2012