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Volume 18; Issue 1

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Nature Medicine
Volume 18; Issue 1

Nature Medicine

Volume 18; Issue 1

1

Dysregulation of immune homeostasis in autoimmune diseases

Kuchroo, Vijay K, Ohashi, Pamela S, Sartor, R Balfour, Vinuesa, Carola G

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 350 KB

english, 2012

2

Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway

Jeong, Hyunkyung, Cohen, Dena E, Cui, Libin, Supinski, Andrea, Savas, Jeffrey N, Mazzulli, Joseph R, Yates, John R, Bordone, Laura, Guarente, Leonard, Krainc, Dimitri

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 905 KB

english, 2011

3

Antibodies targeting the catalytic zinc complex of activated matrix metalloproteinases show therapeutic potential

Sela-Passwell, Netta, Kikkeri, Raghavendra, Dym, Orly, Rozenberg, Haim, Margalit, Raanan, Arad-Yellin, Rina, Eisenstein, Miriam, Brenner, Ori, Shoham, Tsipi, Danon, Tamar

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2011

4

In vivo imaging of ligand receptor binding with Gaussia luciferase complementation

Luker, Kathryn E, Mihalko, Laura Anne, Schmidt, Bradley T, Lewin, Sarah A, Ray, Paramita, Shcherbo, Dmitry, Chudakov, Dmitriy M, Luker, Gary D

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2011

5

Finding a sirtuin truth in Huntington's disease

La Spada, Albert R

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 217 KB

english, 2012

6

Reciprocal repression between P53 and TCTP

Amson, Robert, Pece, Salvatore, Lespagnol, Alexandra, Vyas, Rajesh, Mazzarol, Giovanni, Tosoni, Daniela, Colaluca, Ivan, Viale, Giuseppe, Rodrigues-Ferreira, Sylvie, Wynendaele, Jessika, Chaloin, Oliv

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 1.45 MB

english, 2011

7

Three-dimensional imaging of the unsectioned adult spinal cord to assess axon regeneration and glial responses after injury

Ertürk, Ali, Mauch, Christoph P, Hellal, Farida, Förstner, Friedrich, Keck, Tara, Becker, Klaus, Jährling, Nina, Steffens, Heinz, Richter, Melanie, Hübener, Mark, Kramer, Edgar, Kirchhoff, Frank, Dodt

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 2.79 MB

english, 2011

8

Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets

Jiang, Mali, Wang, Jiawei, Fu, Jinrong, Du, Lin, Jeong, Hyunkyung, West, Tim, Xiang, Lan, Peng, Qi, Hou, Zhipeng, Cai, Huan, Seredenina, Tamara, Arbez, Nicolas, Zhu, Shanshan, Sommers, Katherine, Qian

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 997 KB

english, 2011

9

Autoimmunity's next top models

Wekerle, Hartmut, Flügel, Alexander, Fugger, Lars, Schett, Georg, Serreze, David

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 280 KB

english, 2012

10

ROS-induced ATF3 causes susceptibility to secondary infections during sepsis-associated immunosuppression

Hoetzenecker, Wolfram, Echtenacher, Bernd, Guenova, Emmanuella, Hoetzenecker, Konrad, Woelbing, Florian, Brück, Jürgen, Teske, Anna, Valtcheva, Nadejda, Fuchs, Kerstin, Kneilling, Manfred, Park, Ji-Hy

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 784 KB

english, 2011

11

Unraveling the autoimmune translational research process layer by layer

Blumberg, Richard S, Dittel, Bonnie, Hafler, David, von Herrath, Matthias, Nestle, Frank O

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2012

12

Host defense against malaria favors Salmonella

MacLennan, Calman A

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 572 KB

english, 2012

13

Tumor strengths and frailties: Aspiring to prevent colon cancer

Maxwell, Patrick H

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 871 KB

english, 2012

14

PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells

Xue, Yuan, Lim, Sharon, Yang, Yunlong, Wang, Zongwei, Jensen, Lasse Dahl Ejby, Hedlund, Eva-Maria, Andersson, Patrik, Sasahara, Masakiyo, Larsson, Ola, Galter, Dagmar, Cao, Renhai, Hosaka, Kayoko, Cao

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 2.21 MB

english, 2011

15

Re-establishing immunological self-tolerance in autoimmune disease

Sakaguchi, Shimon, Powrie, Fiona, Ransohoff, Richard M

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 2.31 MB

english, 2012

16

Optimization of current and future therapy for autoimmune diseases

Steinman, Lawrence, Merrill, Joan T, McInnes, Iain B, Peakman, Mark

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 658 KB

english, 2012

17

EU court gets tough on patent extensions for combo products

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 70 KB

english, 2012

18

Key contribution of CPEB4-mediated translational control to cancer progression

Ortiz-Zapater, Elena, Pineda, David, Martínez-Bosch, Neus, Fernández-Miranda, Gonzalo, Iglesias, Mar, Alameda, Francesc, Moreno, Mireia, Eliscovich, Carolina, Eyras, Eduardo, Real, Francisco X, Méndez

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2011

19

The problems and promises of research into human immunology and autoimmune disease

Roep, Bart O, Buckner, Jane, Sawcer, Stephen, Toes, Rene, Zipp, Frauke

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 214 KB

english, 2012

20

Drugmaker reaps what it sows with first plant-made biologic

Williams, Sarah C P

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 80 KB

english, 2012

21

Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease

Koyama, Motoko, Kuns, Rachel D, Olver, Stuart D, Raffelt, Neil C, Wilson, Yana A, Don, Alistair L J, Lineburg, Katie E, Cheong, Melody, Robb, Renee J, Markey, Kate A, Varelias, Antiopi, Malissen, Bern

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 4.37 MB

english, 2011

22

Immunology: Dendritic cell demise

Da Silva, Kevin

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 222 KB

english, 2012

23

Malaria impairs resistance to Salmonella through heme- and heme oxygenase–dependent dysfunctional granulocyte mobilization

Cunnington, Aubrey J, de Souza, J Brian, Walther, Michael, Riley, Eleanor M

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 1.49 MB

english, 2011

24

Next-generation proteasome blockers promise safer cancer therapy

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 169 KB

english, 2012

25

Tumor strengths and frailties: Cancer SUMmOns Otto's metabolism

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 204 KB

english, 2012

26

Biotech entrepreneurs swoon over proposed fundraising changes

Venkataramanan, Madhumita

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 394 KB

english, 2012

27

Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling

Wong, Victor W, Rustad, Kristine C, Akaishi, Satoshi, Sorkin, Michael, Glotzbach, Jason P, Januszyk, Michael, Nelson, Emily R, Levi, Kemal, Paterno, Josemaria, Vial, Ivan N, Kuang, Anna A, Longaker, M

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2011

28

Successful prenatal mannose treatment for congenital disorder of glycosylation-Ia in mice

Schneider, Anette, Thiel, Christian, Rindermann, Jan, DeRossi, Charles, Popovici, Diana, Hoffmann, Georg F, Gröne, Hermann-Josef, Körner, Christian

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 772 KB

english, 2011

29

Antimicrobials: An alternative strategy

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 222 KB

english, 2012

30

Correction

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 169 KB

english, 2012

31

HHS ruling on Plan B introduces new risk for drugmakers

Willyard, Cassandra

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 62 KB

english, 2012

32

Straight talk with... Ronald DePinho

Hersher, Rebecca

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 210 KB

english, 2012

33

Psychiatric disorders: Partners in crime

Chmielnicki, Eva

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 222 KB

english, 2012

34

Are drugmakers fishing for a market with prescription omega-3s?

Hersher, Rebecca

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 188 KB

english, 2012

35

New NIH genetics center focuses its lens on exome, despite doubts

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 62 KB

english, 2012

36

Fighting science with politics

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 86 KB

english, 2012

37

One way to help science: become Republican

Otto, Shawn Lawrence

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 118 KB

english, 2012

38

Socially acceptable

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 81 KB

english, 2012

39

Telomerase at the center of collapsing glomerulopathy

Chugh, Sumant S, Clement, Lionel C

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 8.78 MB

english, 2012

40

PDGF-B exploits stromal EPO

McGinnis, Lisa M, Kuo, Calvin J

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 3.11 MB

english, 2012

41

News in brief: Biomedical briefing

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 478 KB

english, 2012

42

More trials are cut short, but not the debate over their trajectory

Venkataramanan, Madhumita

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 70 KB

english, 2012

43

An act of tolerance

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 957 KB

english, 2012

44

Reversible cell-cycle entry in adult kidney podocytes through regulated control of telomerase and Wnt signaling

Shkreli, Marina, Sarin, Kavita Y, Pech, Matthew F, Papeta, Natalia, Chang, Woody, Brockman, Stephanie A, Cheung, Peggie, Lee, Eunice, Kuhnert, Frank, Olson, Jean L, Kuo, Calvin J, Gharavi, Ali G, D'Ag

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 3.06 MB

english, 2011

45

The value of HPV vaccination

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 105 KB

english, 2012

46

Metabolism: Athero: all but Sirt-ain?

Levinson, Randy

Journal:

Nature Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 223 KB

english, 2012