Volume 17; Issue 12

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Nature Medicine
Volume 17; Issue 12

Nature Medicine

Volume 17; Issue 12

1

A mechanism for glycoconjugate vaccine activation of the adaptive immune system and its implications for vaccine design

Avci, Fikri Y, Li, Xiangming, Tsuji, Moriya, Kasper, Dennis L

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2011

2

Mesenchymal stem cell–based tissue regeneration is governed by recipient T lymphocytes via IFN-γ and TNF-α

Liu, Yi, Wang, Lei, Kikuiri, Takashi, Akiyama, Kentaro, Chen, Chider, Xu, Xingtian, Yang, Ruili, Chen, WanJun, Wang, Songlin, Shi, Songtao

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 1.97 MB

english, 2011

3

Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease

Ebrahimkhani, Mohammad R, Oakley, Fiona, Murphy, Lindsay B, Mann, Jelena, Moles, Anna, Perugorria, Maria J, Ellis, Elizabeth, Lakey, Anne F, Burt, Alastair D, Douglass, Angela

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 875 KB

english, 2011

4

Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut

Shulzhenko, Natalia, Morgun, Andrey, Hsiao, William, Battle, Michele, Yao, Michael, Gavrilova, Oksana, Orandle, Marlene, Mayer, Lloyd, Macpherson, Andrew J, McCoy, Kathy D

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 1.95 MB

english, 2011

5

Identification of a central role for complement in osteoarthritis

Wang, Qian, Rozelle, Andrew L, Lepus, Christin M, Scanzello, Carla R, Song, Jason J, Larsen, D Meegan, Crish, James F, Bebek, Gurkan, Ritter, Susan Y, Lindstrom, Tamsin M

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2011

6

Databases aim to bridge the East-West divide of drug discovery

Sanderson, Katharine

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 77 KB

english, 2011

7

Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome

Paşca, Sergiu P, Portmann, Thomas, Voineagu, Irina, Yazawa, Masayuki, Shcheglovitov, Aleksandr, Paşca, Anca M, Cord, Branden, Palmer, Theo D, Chikahisa, Sachiko, Nishino, Seiji

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2011

8

Cancer cell–selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules

Mitsunaga, Makoto, Ogawa, Mikako, Kosaka, Nobuyuki, Rosenblum, Lauren T, Choyke, Peter L, Kobayashi, Hisataka

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2011

9

Inhibition of proteasome deubiquitinating activity as a new cancer therapy

D'Arcy, Pádraig, Brnjic, Slavica, Olofsson, Maria Hägg, Fryknäs, Mårten, Lindsten, Kristina, De Cesare, Michelandrea, Perego, Paola, Sadeghi, Behnam, Hassan, Moustapha, Larsson, Rolf, Linder, Stig

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 754 KB

english, 2011

10

Stressed tumor cell, chemosensitized cancer

Wiemer, Erik A C

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 357 KB

english, 2011

11

miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response

Mateescu, Bogdan, Batista, Luciana, Cardon, Melissa, Gruosso, Tina, de Feraudy, Yvan, Mariani, Odette, Nicolas, André, Meyniel, Jean-Philippe, Cottu, Paul, Sastre-Garau, Xavier, Mechta-Grigoriou, Fati

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 1.69 MB

english, 2011

12

The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2

Yang, Baofeng, Lin, Huixian, Xiao, Jiening, Lu, Yanjie, Luo, Xiaobin, Li, Baoxin, Zhang, Ying, Xu, Chaoqian, Bai, Yunlong, Wang, Huizhen, Chen, Guohao, Wang, Zhiguo

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 69 KB

english, 2011

13

A gut triumvirate rules homeostasis

Chorny, Alejo, Cerutti, Andrea

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 394 KB

english, 2011

14

Improving the efficacy of translational medicine by optimally integrating health care, academia and industry

Bornstein, Stefan R, Licinio, Julio

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 138 KB

english, 2011

15

Mannose-binding lectin—the forgotten molecule?

Osthoff, Michael, Trendelenburg, George, Eisen, Damon P, Trendelenburg, Marten

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 109 KB

english, 2011

16

Nuclear factor-κB1 controls the functional maturation of dendritic cells and prevents the activation of autoreactive T cells

Dissanayake, Dilan, Hall, Håkan, Berg-Brown, Nancy, Elford, Alisha R, Hamilton, Sara R, Murakami, Kiichi, Deluca, Leslie Summers, Gommerman, Jennifer L, Ohashi, Pamela S

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 791 KB

english, 2011

17

Autoimmunity: Defects in DC tolerance

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 173 KB

english, 2011

18

Immunotherapy: A safety switch for immunotherapy

Farrell, Alison

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 173 KB

english, 2011

19

Neurological disorders: Serine to the rescue

Basson, Michael

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 173 KB

english, 2011

20

Nitrite-NO bailout for a NOS complex too big to fail

Gladwin, Mark T, Tejero, Jesús

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 447 KB

english, 2011

21

Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer

Robinson, Dan R, Kalyana-Sundaram, Shanker, Wu, Yi-Mi, Shankar, Sunita, Cao, Xuhong, Ateeq, Bushra, Asangani, Irfan A, Iyer, Matthew, Maher, Christopher A, Grasso, Catherine S, Lonigro, Robert J, Quis

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 818 KB

english, 2011

22

Diagnosis in a dish: your skin can help your brain

Huttner, Anita, Rakic, Pasko

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 420 KB

english, 2011

23

Fruitful progress to fertility: Male fertility in the test tube

Clark, Amander T, Phillips, Bart T, Orwig, Kyle E

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 407 KB

english, 2011

24

A MEK-independent role for CRAF in mitosis and tumor progression

Mielgo, Ainhoa, Seguin, Laetitia, Huang, Miller, Camargo, Maria Fernanda, Anand, Sudarshan, Franovic, Aleksandra, Weis, Sara M, Advani, Sunil J, Murphy, Eric A, Cheresh, David A

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2011

25

Drugs in traffic: the road to approval

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 265 KB

english, 2011

26

The history of hemophilia

High, Katherine A.

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 103 KB

english, 2011

27

Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge

Hansen, Scott G, Vieville, Cassandra, Whizin, Nathan, Coyne-Johnson, Lia, Siess, Don C, Drummond, Derek D, Legasse, Alfred W, Axthelm, Michael K, Oswald, Kelli, Trubey, Charles M, Piatak, Michael, Lif

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 128 KB

english, 2011

28

The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2

Yang, Baofeng, Lin, Huixian, Xiao, Jiening, Lu, Yanjie, Luo, Xiaobin, Li, Baoxin, Zhang, Ying, Xu, Chaoqian, Bai, Yunlong, Wang, Huizhen, Chen, Guohao, Wang, Zhiguo

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 69 KB

english, 2011

29

Biostatisticians call for more scientifically rigorous pilot studies

Willyard, Cassandra

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 77 KB

english, 2011

30

Resolving controversies on the path to Alzheimer's therapeutics

Selkoe, Dennis J

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 69 KB

english, 2011

31

Oxidation of CaMKII determines the cardiotoxic effects of aldosterone

He, B Julie, Joiner, Mei-ling A, Singh, Madhu V, Luczak, Elizabeth D, Swaminathan, Paari Dominic, Koval, Olha M, Kutschke, William, Allamargot, Chantal, Yang, Jinying, Guan, Xiaoqun, Zimmerman, Kathy,

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 1.64 MB

english, 2011

32

Targeting osteoclast-osteoblast communication

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 69 KB

english, 2011

33

The Yearbook

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 171 KB

english, 2011

34

Efficient drug approval and monitoring must rely on sound regulatory science

Meagher, Emma A, FitzGerald, Garret A

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 177 KB

english, 2011

35

Breaking the silence

Katsnelson, Alla

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 857 KB

english, 2011

36

Four-in-one HIV pill may be exception among combination drugs

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 127 KB

english, 2011

37

Intra-arterial catheter for simultaneous microstructural and molecular imaging in vivo

Yoo, Hongki, Kim, Jin Won, Shishkov, Milen, Namati, Eman, Morse, Theodore, Shubochkin, Roman, McCarthy, Jason R, Ntziachristos, Vasilis, Bouma, Brett E, Jaffer, Farouc A, Tearney, Guillermo J

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2011

38

Patent-sharing scheme for neglected diseases may have catch

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 90 KB

english, 2011

39

Reaction to retractions

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 89 KB

english, 2011

40

Corrections

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 90 KB

english, 2011

41

2011 in review

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 171 KB

english, 2011

42

Reply to: Mannose-binding lectin—the forgotten molecule?

Iadecola, Costantino, Anrather, Josef

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 81 KB

english, 2011

43

Notable advances 2011

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2011

44

NF-κB in DCs: it takes effort to be immature

Creusot, Rémi J

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 475 KB

english, 2011

45

A hepatocyte growth factor receptor (Met)−insulin receptor hybrid governs hepatic glucose metabolism

Fafalios, Arlee, Ma, Jihong, Tan, Xinping, Stoops, John, Luo, Jianhua, DeFrances, Marie C, Zarnegar, Reza

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2011

46

Genome center's location stuck in transit

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 222 KB

english, 2011

47

Class of once-weekly diabetes drugs poised for approval

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 658 KB

english, 2011

48

Straight talk with... Amanda Glassman

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 349 KB

english, 2011

49

Trial networks move beyond single-disease strategies

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 227 KB

english, 2011

50

A retrospective of retractions: the striking record in 2011

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 84 KB

english, 2011

51

News in brief: Biomedical briefing

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 640 KB

english, 2011

52

Timeline of events: A brief history of what made news this year

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 130 KB

english, 2011

53

Fruitful progress to fertility: Preserving oocytes from chemodestruction

Xu, Min, Pavone, Mary Ellen, Woodruff, Teresa

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2011

54

Addiction: One thing leads to another

López, Juan Carlos

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 173 KB

english, 2011

55

International coding upgrade affects clinical research and reviews

Venkataramanan, Madhumita

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 95 KB

english, 2011

56

Institutes unite to put New York on the biopharma map

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 222 KB

english, 2011

57

A sweet T cell response

Rappuoli, Rino, De Gregorio, Ennio

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 247 KB

english, 2011

58

The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis

Cudkowicz, Merit, Bozik, Michael E, Ingersoll, Evan W, Miller, Robert, Mitsumoto, Hiroshi, Shefner, Jeremy, Moore, Dan H, Schoenfeld, David, Mather, James L, Archibald, Donald, Sullivan, Mary, Amburge

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 475 KB

english, 2011

59

New HCV drugs trigger race for more tolerable therapies

Williams, Sarah C P

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 92 KB

english, 2011

60

Mixed results for a malaria vaccine

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 209 KB

english, 2011

61

Requirement of argininosuccinate lyase for systemic nitric oxide production

Erez, Ayelet, Nagamani, Sandesh C S, Shchelochkov, Oleg A, Premkumar, Muralidhar H, Campeau, Philippe M, Chen, Yuqing, Garg, Harsha K, Li, Li, Mian, Asad, Bertin, Terry K, Black, Jennifer O, Zeng, Hen

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 991 KB

english, 2011