Volume 9; Issue 6

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Molecular Pharmaceutics
Volume 9; Issue 6

Molecular Pharmaceutics

Volume 9; Issue 6

1

The Transcription Factor GCF2 Is an Upstream Repressor of the Small GTPAse RhoA, Regulating Membrane Protein Trafficking, Sensitivity to Doxorubicin, and Resistance to Cisplatin

Shen, Ding-Wu, Pouliot, Lynn M., Gillet, Jean-Pierre, Ma, Wenting, Johnson, Alfred C., Hall, Matthew D., Gottesman, Michael M.

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 5.71 MB

english, 2012

2

Targeted Delivery of Insoluble Cargo (Paclitaxel) by PEGylated Chitosan Nanoparticles Grafted with Arg-Gly-Asp (RGD)

Lv, Pi-Ping, Ma, Yu-Feng, Yu, Rong, Yue, Hua, Ni, De-Zhi, Wei, Wei, Ma, Guang-Hui

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 4.50 MB

english, 2012

3

No Correlation between the Expression of FXR and Genes Involved in Multidrug Resistance Phenotype of Primary Liver Tumors

Martinez-Becerra, P., Vaquero, J., Romero, M. R., Lozano, E., Anadon, C., Macias, R. I. R., Serrano, M. A., Grañé-Boladeras, N., Muñoz-Bellvis, L., Alvarez, L., Sangro, B., Pastor-Anglada, M., Marin,

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 4.63 MB

english, 2012

4

A Peptidomimetic Tight Junction Modulator To Improve Regional Analgesia

Zwanziger, Denise, Hackel, Dagmar, Staat, Christian, Böcker, Alexander, Brack, Alexander, Beyermann, Michael, Rittner, Heike, Blasig, Ingolf E.

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 2.56 MB

english, 2012

5

Synthetic MicroRNA Cassette Dosing: Pharmacokinetics, Tissue Distribution and Bioactivity

Wang, Hongyan, Chiu, Ming, Xie, Zhiliang, Chiu, Michael, Liu, Zhongfa, Chen, Ping, Liu, Shujun, Byrd, John C., Muthusamy, Natarajan, Garzon, Ramiro, Croce, Carlo M., Marcucci, Guido, Chan, Kenneth K.

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 377 KB

english, 2012

6

Investigating the Recrystallization Behavior of Amorphous Paracetamol by Variable Temperature Raman Studies and Surface Raman Mapping

Nanubolu, Jagadeesh Babu, Burley, Jonathan C.

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 6.19 MB

english, 2012

7

Efficient in Vitro siRNA Delivery and Intramuscular Gene Silencing Using PEG-Modified PAMAM Dendrimers

Tang, Yin, Li, Yang-Bing, Wang, Bo, Lin, Ri-Yuan, van Dongen, Mallory, Zurcher, Danielle M., Gu, Xiao-Yan, Banaszak Holl, Mark M., Liu, George, Qi, Rong

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 4.36 MB

english, 2012

8

In Vivo Biodistribution of Prion- and GM1-Targeted Polymersomes following Intravenous Administration in Mice

Stojanov, Katica, Georgieva, Julia V., Brinkhuis, René P., van Hest, Jan C., Rutjes, Floris P., Dierckx, Rudi A. J. O., de Vries, Erik F. J., Zuhorn, Inge S.

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 917 KB

english, 2012

9

Dielectric Studies on Molecular Dynamics of Two Important Disaccharides: Sucrose and Trehalose

Kaminski, K., Adrjanowicz, K., Zakowiecki, D., Kaminska, E., Wlodarczyk, P., Paluch, M., Pilch, J., Tarnacka, M.

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 3.75 MB

english, 2012

10

Cationic PAMAM Dendrimers Disrupt Key Platelet Functions

Jones, Clinton F., Campbell, Robert A., Franks, Zechariah, Gibson, Christopher C., Thiagarajan, Giridhar, Vieira-de-Abreu, Adriana, Sukavaneshvar, Sivaprasad, Mohammad, S. Fazal, Li, Dean Y., Ghandeha

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 522 KB

english, 2012

11

Synthesis of Bisethylnorspermine Lipid Prodrug as Gene Delivery Vector Targeting Polyamine Metabolism in Breast Cancer

Dong, Yanmei, Zhu, Yu, Li, Jing, Zhou, Qing-Hui, Wu, Chao, Oupický, David

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 482 KB

english, 2012

12

Iron Oxide/Hydroxide Nanoparticles with Negatively Charged Shells Show Increased Uptake in Caco-2 Cells

Jahn, Markus R., Nawroth, Thomas, Fütterer, Sören, Wolfrum, Uwe, Kolb, Ute, Langguth, Peter

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 2.47 MB

english, 2012

13

Episodic Transdermal Delivery of Testosterone

Malik, Ritu, Venkatesh, K. S., Dwivedi, Anil Kumar, Misra, Amit

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 904 KB

english, 2012

14

Ultrasensitive Capillary Electrophoretic Analysis of Potentially Immunogenic Carbohydrate Residues in Biologics: Galactose-α-1,3-Galactose Containing Oligosaccharides

Szabo, Zoltan, Guttman, Andras, Bones, Jonathan, Shand, Randi L., Meh, David, Karger, Barry L.

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 319 KB

english, 2012

15

Pyropheophorbide A and c(RGDyK) Comodified Chitosan-Wrapped Upconversion Nanoparticle for Targeted Near-Infrared Photodynamic Therapy

Zhou, Aiguo, Wei, Yanchun, Wu, Baoyan, Chen, Qun, Xing, Da

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 2.53 MB

english, 2012

16

Lipase Is Essential for the Study of in Vitro Release Kinetics from Organogels

Dufresne, Marie-Hélène, Marouf, Elaheh, Kränzlin, Yvonne, Gauthier, Marc A., Leroux, Jean-Christophe

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2012

17

New 99m Tc(CO) 3 Mannosylated Dextran Bearing S-Derivatized Cysteine Chelator for Sentinel Lymph Node Detection

Pirmettis, I., Arano, Y., Tsotakos, T., Okada, K., Yamaguchi, A., Uehara, T., Morais, M., Correia, J. D. G., Santos, I., Martins, M., Pereira, S., Triantis, C., Kyprianidou, P., Pelecanou, M., Papadop

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 3.93 MB

english, 2012

18

Prodrug Strategy for PSMA-Targeted Delivery of TGX-221 to Prostate Cancer Cells

Zhao, Yunqi, Duan, Shaofeng, Zeng, Xing, Liu, Chunjing, Davies, Neal M., Li, Benyi, Forrest, M. Laird

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 1.59 MB

english, 2012

19

FINDSITE X : A Structure-Based, Small Molecule Virtual Screening Approach with Application to All Identified Human GPCRs

Zhou, Hongyi, Skolnick, Jeffrey

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 577 KB

english, 2012

20

Delivery of Peptides to the Blood and Brain after Oral Uptake of Quaternary Ammonium Palmitoyl Glycol Chitosan Nanoparticles

Lalatsa, A., Garrett, N. L., Ferrarelli, T., Moger, J., Schätzlein, A. G., Uchegbu, I. F.

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 4.40 MB

english, 2012

21

A Prodrug Nanoparticle Approach for the Oral Delivery of a Hydrophilic Peptide, Leucine 5 -enkephalin, to the Brain

Lalatsa, Aikaterini, Lee, Vivian, Malkinson, John P., Zloh, Mire, Schätzlein, Andreas G., Uchegbu, Ijeoma F.

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 4.50 MB

english, 2012

22

Enhanced Prostate Cancer Targeting by Modified Protease Sensitive Photosensitizer Prodrugs

Zuluaga, Maria-Fernanda, Gabriel, Doris, Lange, Norbert

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 3.11 MB

english, 2012

23

Disulfide Cross-Linked Micelles for the Targeted Delivery of Vincristine to B-Cell Lymphoma

Kato, Jason, Li, Yuanpei, Xiao, Kai, Lee, Joyce S., Luo, Juntao, Tuscano, Joseph M., O’Donnell, Robert T., Lam, Kit S.

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 4.66 MB

english, 2012

24

The hERG Channel Is Dependent upon the Hsp90α Isoform for Maturation and Trafficking

Peterson, Laura B., Eskew, Jeffrey D., Vielhauer, George A., Blagg, Brian S. J.

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 3.14 MB

english, 2012

25

Potential Use of Lactosylated Dendrimer (G3)/α-Cyclodextrin Conjugates as Hepatocyte-Specific siRNA Carriers for the Treatment of Familial Amyloidotic Polyneuropathy

Hayashi, Yuya, Mori, Yoshimasa, Yamashita, Shogo, Motoyama, Keiichi, Higashi, Taishi, Jono, Hirofumi, Ando, Yukio, Arima, Hidetoshi

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 2.65 MB

english, 2012

26

Transferrin-Modified c[RGDfK]-Paclitaxel Loaded Hybrid Micelle for Sequential Blood-Brain Barrier Penetration and Glioma Targeting Therapy

Zhang, Pengcheng, Hu, Luojuan, Yin, Qi, Feng, Linyin, Li, Yaping

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 4.67 MB

english, 2012

27

Molecular Dynamics in Supercooled Liquid and Glassy States of Antibiotics: Azithromycin, Clarithromycin and Roxithromycin Studied by Dielectric Spectroscopy. Advantages Given by the Amorphous State

Adrjanowicz, K., Zakowiecki, D., Kaminski, K., Hawelek, L., Grzybowska, K., Tarnacka, M., Paluch, M., Cal, K.

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 6.55 MB

english, 2012

28

Systemic Delivery Systems of Angiogenic Gene by Novel Bubble Liposomes Containing Cationic Lipid and Ultrasound Exposure

Negishi, Yoichi, Endo-Takahashi, Yoko, Matsuki, Yuki, Kato, Yasuharu, Takagi, Norio, Suzuki, Ryo, Maruyama, Kazuo, Aramaki, Yukihiko

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 1.92 MB

english, 2012

29

Deposition, Diffusion and Transport Mechanism of Dry Powder Microparticulate Salbutamol, at the Respiratory Epithelia

Haghi, Mehra, Traini, Daniela, Bebawy, Mary, Young, Paul M.

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 1.60 MB

english, 2012

30

The Fraction Dose Absorbed, in Humans, and High Jejunal Human Permeability Relationship

Dahan, Arik, Lennernäs, Hans, Amidon, Gordon L.

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 1.91 MB

english, 2012

31

Heparan Sulfate Proteoglycan-Mediated Entry Pathway for Charged Tri-Platinum Compounds: Differential Cellular Accumulation Mechanisms for Platinum

Silva, Heveline, Frézard, Frédéric, Peterson, Erica J., Kabolizadeh, Peyman, Ryan, John J., Farrell, Nicholas P.

Journal:

Molecular Pharmaceutics

Année:

2012

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2012