Volume 5; Issue 10

Main
ACS Chemical Neuroscience
Volume 5; Issue 10

ACS Chemical Neuroscience

Volume 5; Issue 10

1

Retinal Prosthetics, Optogenetics, and Chemical Photoswitches

Marc, Robert, Pfeiffer, Rebecca, Jones, Bryan

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 2.09 MB

english, 2014

2

Design, Synthesis, and Evaluation of Multitarget-Directed Selenium-Containing Clioquinol Derivatives for the Treatment of Alzheimer’s Disease

Wang, Zhiren, Wang, Yali, Li, Wenrui, Mao, Fei, Sun, Yang, Huang, Ling, Li, Xingshu

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 9.70 MB

english, 2014

3

Understanding the Role α7 Nicotinic Receptors Play in Dopamine Efflux in Nucleus Accumbens

Maex, Reinoud, Grinevich, Vladimir P., Grinevich, Valentina, Budygin, Evgeny, Bencherif, Merouane, Gutkin, Boris

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 995 KB

english, 2014

4

Priming the Cellular Glycocalyx for Neural Development

Huang, Mia L., Godula, Kamil

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 944 KB

english, 2014

5

Mice Genetically Depleted of Brain Serotonin Do Not Display a Depression-like Behavioral Phenotype

Angoa-Pérez, Mariana, Kane, Michael J., Briggs, Denise I., Herrera-Mundo, Nieves, Sykes, Catherine E., Francescutti, Dina M., Kuhn, Donald M.

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 2.34 MB

english, 2014

6

JNJ-40255293, a Novel Adenosine A 2A /A 1 Antagonist with Efficacy in Preclinical Models of Parkinson’s Disease

Atack, John R., Shook, Brian C., Rassnick, Stefanie, Jackson, Paul F., Rhodes, Kenneth, Drinkenburg, Wilhelmus H., Ahnaou, Abdallah, te Riele, Paula, Langlois, Xavier, Hrupka, Brian, De Haes, Patrick,

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 4.29 MB

english, 2014

7

PET Imaging Demonstrates Histone Deacetylase Target Engagement and Clarifies Brain Penetrance of Known and Novel Small Molecule Inhibitors in Rat

Schroeder, F. A., Wang, C., Van de Bittner, G. C., Neelamegam, R., Takakura, W. R., Karunakaran, A., Wey, H. Y., Reis, S. A., Gale, J., Zhang, Y. L., Holson, E. B., Haggarty, S. J., Hooker, J. M.

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 3.12 MB

english, 2014

8

Analysis and Synthesis in Olfaction

Rokni, Dan, Murthy, Venkatesh N.

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 791 KB

english, 2014

9

Deciphering the Function and Regulation of microRNAs in Alzheimer’s Disease and Parkinson’s Disease

Qiu, Lifeng, Zhang, Wei, Tan, Eng King, Zeng, Li

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 745 KB

english, 2014

10

Antipsychotic Haloperidol Binding to the Human Dopamine D3 Receptor: Beyond Docking Through QM/MM Refinement Toward the Design of Improved Schizophrenia Medicines

Zanatta, Geancarlo, Nunes, Gustavo, Bezerra, Eveline M., da Costa, Roner F., Martins, Alice, Caetano, Ewerton W. S., Freire, Valder N., Gottfried, Carmem

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 4.58 MB

english, 2014

11

The Potential of Indole and a Synthetic Derivative for PolyQ Aggregation Reduction by Enhancement of the Chaperone and Autophagy Systems

Lin, Chih-Hsin, Wu, Yih-Ru, Kung, Pin-Jui, Chen, Wan-Ling, Lee, Li-Ching, Lin, Te-Hsien, Chao, Chih-Ying, Chen, Chiung-Mei, Chang, Kuo-Hsuan, Janreddy, Donala, Lee-Chen, Guey-Jen, Yao, Ching-Fa

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 5.89 MB

english, 2014

12

Striatal Dopamine Homeostasis is Altered in Mice Following Roux-en-Y Gastric Bypass Surgery

Reddy, India A., Wasserman, David H., Ayala, Julio E., Hasty, Alyssa H., Abumrad, Naji N., Galli, Aurelio

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2014

13

Elevating Standards for Discoveries Reported in ACS Chemical Neuroscience : New Criteria to Enhance Reproducibility, Experimental Transparency, Reliability, and the Value of Negative Data

Lindsley, Craig W.

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 133 KB

english, 2014

14

In This Issue, Volume 5, Issue 10

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 503 KB

english, 2014

15

Hydrogen Sulfide: A Neuromodulator and Neuroprotectant in the Central Nervous System

Zhang, Xingzhou, Bian, Jin-Song

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 914 KB

english, 2014

16

Synthesis and Evaluation of Translocator 18 kDa Protein (TSPO) Positron Emission Tomography (PET) Radioligands with Low Binding Sensitivity to Human Single Nucleotide Polymorphism rs6971

Zanotti-Fregonara, Paolo, Zhang, Yi, Jenko, Kimberly J., Gladding, Robert L., Zoghbi, Sami S., Fujita, Masahiro, Sbardella, Gianluca, Castellano, Sabrina, Taliani, Sabrina, Martini, Claudia, Innis, Ro

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 831 KB

english, 2014

17

Selective Interception of Gelsolin Amyloidogenic Stretch Results in Conformationally Distinct Aggregates with Reduced Toxicity

Arya, Prabha, Srivastava, Ankit, Vasaikar, Suhas V., Mukherjee, Goutam, Mishra, Prashant, Kundu, Bishwajit

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 6.63 MB

english, 2014

18

Synthesis, Biophysical, and Pharmacological Evaluation of the Melanocortin Agonist AST3-88: Modifications of Peptide Backbone at Trp 7 Position Lead to a Potent, Selective, and Stable Ligand of the Melanocortin 4 Receptor (MC4R)

Singh, Anamika, Dirain, Marvin L., Wilczynski, Andrzej, Chen, Chi, Gosnell, Blake A., Levine, Allen S., Edison, Arthur S., Haskell-Luevano, Carrie

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 3.55 MB

english, 2014

19

Zebrafish Bioassay-Guided Microfractionation Identifies Anticonvulsant Steroid Glycosides from the Philippine Medicinal Plant Solanum torvum

Challal, Soura, Buenafe, Olivia E. M., Queiroz, Emerson F., Maljevic, Snezana, Marcourt, Laurence, Bock, Merle, Kloeti, Werner, Dayrit, Fabian M., Harvey, Alan L., Lerche, Holger, Esguerra, Camila V.,

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 2.20 MB

english, 2014

20

Development of a Photoactivatable Allosteric Ligand for the M 1 Muscarinic Acetylcholine Receptor

Davie, Briana J., Sexton, Patrick M., Capuano, Ben, Christopoulos, Arthur, Scammells, Peter J.

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 321 KB

english, 2014

21

Selective Activation of M 4 Muscarinic Acetylcholine Receptors Reverses MK-801-Induced Behavioral Impairments and Enhances Associative Learning in Rodents

Bubser, Michael, Bridges, Thomas M., Dencker, Ditte, Gould, Robert W., Grannan, Michael, Noetzel, Meredith J., Lamsal, Atin, Niswender, Colleen M., Daniels, J. Scott, Poslusney, Michael S., Melancon,

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 8.23 MB

english, 2014

22

De Novo Design of Self-Assembled Hexapeptides as β-Amyloid (Aβ) Peptide Inhibitors

Wang, Qiuming, Liang, Guizhao, Zhang, Mingzhen, Zhao, Jun, Patel, Kunal, Yu, Xiang, Zhao, Chao, Ding, Binrong, Zhang, Ge, Zhou, Feimeng, Zheng, Jie

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 4.08 MB

english, 2014

23

Structure–Activity Relationship Study around Guanabenz Identifies Two Derivatives Retaining Antiprion Activity but Having Lost α2-Adrenergic Receptor Agonistic Activity

Nguyen, Phu hai, Hammoud, Hassan, Halliez, Sophie, Pang, Yanhong, Evrard, Justine, Schmitt, Martine, Oumata, Nassima, Bourguignon, Jean-Jacques, Sanyal, Suparna, Beringue, Vincent, Blondel, Marc, Bihe

Journal:

ACS Chemical Neuroscience

Année:

2014

Langue:

english

Fichier:

PDF, 1.76 MB

english, 2014