Journal of Molecular Biology

1

Evidence for a Tyrosine–Adenine Stacking Interaction and for a Short-lived Open Intermediate Subsequent to Initial Binding of Escherichia coli RNA Polymerase to Promoter DNA

Lisa A. Schroeder, Theodore J. Gries, Ruth M. Saecker, M. Thomas Record Jr, Michael E. Harris, Pieter L. deHaseth

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 678 KB

english, 2009

2

Kinetic Analysis of Late Steps of Eukaryotic Translation Initiation

Michael G. Acker, Byung-Sik Shin, Jagpreet S. Nanda, Adesh K. Saini, Thomas E. Dever, Jon R. Lorsch

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2009

3

Collective motions in Glucosamine-6-phosphate Synthase: Influence of Ligand Binding and role in Ammonia Channelling and Opening of the Fructose-6-Phosphate Binding Site

Nicolas Floquet, Philippe Durand, Bernard Maigret, Bernard Badet, Marie-Ange Badet-Denisot, David Perahia

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 2.37 MB

english, 2009

4

Head–Head Interaction Characterizes the Relaxed State of Limulus Muscle Myosin Filaments

Fa-Qing Zhao, Roger Craig, John L. Woodhead

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2009

5

Crystallographic Analysis of a Sex-Specific Enhancer Element: Sequence-Dependent DNA Structure, Hydration, and Dynamics

Narendra Narayana, Michael A. Weiss

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 4.84 MB

english, 2009

6

E2–c-Cbl Recognition Is Necessary but not Sufficient for Ubiquitination Activity

Anding Huang, Rob N. de Jong, Hans Wienk, G. Sebastiaan Winkler, H. Th. Marc Timmers, Rolf Boelens

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 2.12 MB

english, 2009

7

Unfolding Thermodynamics of the Δ-Domain in the Prohead I Subunit of Phage HK97: Determination by Factor Analysis of Raman Spectra

Daniel Němeček, Stacy A. Overman, Roger W. Hendrix, George J. Thomas Jr

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.94 MB

english, 2009

8

Structure and Action of the Myxobacterial Chondrochloren Halogenase CndH: A New Variant of FAD-dependent Halogenases

Stefan Buedenbender, Shwan Rachid, Rolf Müller, Georg E. Schulz

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 2.10 MB

english, 2009

9

A Structural Basis for the Regulatory Inactivation of DnaA

Qingping Xu, Daniel McMullan, Polat Abdubek, Tamara Astakhova, Dennis Carlton, Connie Chen, Hsiu-Ju Chiu, Thomas Clayton, Debanu Das, Marc C. Deller, Lian Duan, Marc-Andre Elsliger, Julie Feuerhelm, J

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 2.03 MB

english, 2009

10

Can Morphing Methods Predict Intermediate Structures?

Dahlia R. Weiss, Michael Levitt

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2009

11

Ribosomal Intersubunit Bridge B2a Is Involved in Factor-Dependent Translation Initiation and Translational Processivity

Kalle Kipper, Csaba Hetényi, Sulev Sild, Jaanus Remme, Aivar Liiv

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.65 MB

english, 2009

12

Mapping of DDR1 Distribution and Oligomerization on the Cell Surface by FRET Microscopy

Cosmin Mihai, Maqsood Chotani, Terry S. Elton, Gunjan Agarwal

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.66 MB

english, 2009

13

Essential Role of PACT-Mediated PKR Activation in Tunicamycin-Induced Apoptosis

Madhurima Singh, Vennece Fowlkes, Indhira Handy, Chandrashekhar V. Patel, Rekha C. Patel

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 880 KB

english, 2009

14

The Ribosomal Grip of the Peptidyl-tRNA is Critical for Reading Frame Maintenance

S. Joakim Näsvall, Kristina Nilsson, Glenn R. Björk

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2009

15

CDC25A Functions as a Novel Ar Corepressor in Prostate Cancer Cells

Yung-Tuen Chiu, Hui-Ying Han, Steve Chin-Lung Leung, Hiu-Fung Yuen, Chee-Wai Chau, Zhiyong Guo, Yun Qiu, Kwok-Wah Chan, Xianghong Wang, Yong-Chuan Wong, Ming-Tat Ling

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2009

16

Crystal Structure of Diaminopimelate Epimerase from Arabidopsis thaliana, an Amino Acid Racemase Critical for l-Lysine Biosynthesis

Bindu Pillai, Vijayalakshmi A. Moorthie, Marco J. van Belkum, Sandra L. Marcus, Maia M. Cherney, Christopher M. Diaper, John C. Vederas, Michael N.G. James

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 4.97 MB

english, 2009

17

Asp-to-Asn Substitution at the First Position of the DxD TOPRIM Motif of Recombinant Bacterial Topoisomerase I Is Extremely Lethal to E. coli

Bokun Cheng, Thirunavukkarasu Annamalai, Elena Sorokin, Maria Abrenica, Sandra Aedo, Yuk-Ching Tse-Dinh

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 894 KB

english, 2009

18

Cryoelectron Microscopy Structure of Purified γ-Secretase at 12 Å Resolution

Pamela Osenkowski, Hua Li, Wenjuan Ye, Dongyang Li, Lorene Aeschbach, Patrick C. Fraering, Michael S. Wolfe, Dennis J. Selkoe, Huilin Li

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2009

19

The Crystal Structure of A Ternary Complex of Betaine Aldehyde Dehydrogenase from Pseudomonas aeruginosa Provides New Insight into the Reaction Mechanism and Shows A Novel Binding Mode of the 2′-Phosphate of NADP+ and A Novel Cation Binding Site

Lilian González-Segura, Enrique Rudiño-Piñera, Rosario A. Muñoz-Clares, Eduardo Horjales

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 3.04 MB

english, 2009

20

Defining the DNA Substrate Binding Sites on HIV-1 Integrase

James Dolan, Aiping Chen, Irene T. Weber, Robert W. Harrison, Jonathan Leis

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.37 MB

english, 2009

21

Structural Base for Enzymatic Cyclodextrin Hydrolysis

Stefan Buedenbender, Georg E. Schulz

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 2.26 MB

english, 2009

22

Halogenated Benzenes Bound within a Non-polar Cavity in T4 Lysozyme Provide Examples of I⋯S and I⋯Se Halogen-bonding

Lijun Liu, Walter A. Baase, Brian W. Matthews

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.51 MB

english, 2009

23

Crystal Structure of the Pml1p Subunit of the Yeast Precursor mRNA Retention and Splicing Complex

Simon Trowitzsch, Gert Weber, Reinhard Lührmann, Markus C. Wahl

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.85 MB

english, 2009

24

The Disulfide Relay System of Mitochondria Is Required for the Biogenesis of Mitochondrial Ccs1 and Sod1

Silvia Reddehase, Barbara Grumbt, Walter Neupert, Kai Hell

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 835 KB

english, 2009

25

In Silico Vaccine Design Based on Molecular Simulations of Rhinovirus Chimeras Presenting HIV-1 gp41 Epitopes

Mauro Lapelosa, Emilio Gallicchio, Gail Ferstandig Arnold, Eddy Arnold, Ronald M. Levy

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.71 MB

english, 2009

26

Diverse Role of Three Tyrosines in Binding of the RNA 5′ Cap to the Human Nuclear Cap Binding Complex

Remigiusz Worch, Marzena Jankowska-Anyszka, Anna Niedzwiecka, Janusz Stepinski, Catherine Mazza, Edward Darzynkiewicz, Stephen Cusack, Ryszard Stolarski

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1018 KB

english, 2009

27

Role of Allosteric Switch Residue Histidine 195 in Maintaining Active-Site Asymmetry in Presynaptic Filaments of Bacteriophage T4 UvsX Recombinase

Joshua N. Farb, Scott W. Morrical

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2009

28

RosettaLigand Docking with Full Ligand and Receptor Flexibility

Ian W. Davis, David Baker

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2009

29

Editorial Board

Journal:

Journal of Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 452 KB

english, 2009

30

Volume 385; Issue 2

Evidence for a Tyrosine–Adenine Stacking Interaction and for a Short-lived Open Intermediate Subsequent to Initial Binding of Escherichia coli RNA Polymerase to Promoter DNA

Kinetic Analysis of Late Steps of Eukaryotic Translation Initiation

Collective motions in Glucosamine-6-phosphate Synthase: Influence of Ligand Binding and role in Ammonia Channelling and Opening of the Fructose-6-Phosphate Binding Site

Head–Head Interaction Characterizes the Relaxed State of Limulus Muscle Myosin Filaments

Crystallographic Analysis of a Sex-Specific Enhancer Element: Sequence-Dependent DNA Structure, Hydration, and Dynamics

E2–c-Cbl Recognition Is Necessary but not Sufficient for Ubiquitination Activity

Unfolding Thermodynamics of the Δ-Domain in the Prohead I Subunit of Phage HK97: Determination by Factor Analysis of Raman Spectra

Structure and Action of the Myxobacterial Chondrochloren Halogenase CndH: A New Variant of FAD-dependent Halogenases

A Structural Basis for the Regulatory Inactivation of DnaA

Can Morphing Methods Predict Intermediate Structures?

Ribosomal Intersubunit Bridge B2a Is Involved in Factor-Dependent Translation Initiation and Translational Processivity

Mapping of DDR1 Distribution and Oligomerization on the Cell Surface by FRET Microscopy

Essential Role of PACT-Mediated PKR Activation in Tunicamycin-Induced Apoptosis

The Ribosomal Grip of the Peptidyl-tRNA is Critical for Reading Frame Maintenance

CDC25A Functions as a Novel Ar Corepressor in Prostate Cancer Cells

Crystal Structure of Diaminopimelate Epimerase from Arabidopsis thaliana, an Amino Acid Racemase Critical for l-Lysine Biosynthesis

Asp-to-Asn Substitution at the First Position of the DxD TOPRIM Motif of Recombinant Bacterial Topoisomerase I Is Extremely Lethal to E. coli

Cryoelectron Microscopy Structure of Purified γ-Secretase at 12 Å Resolution

The Crystal Structure of A Ternary Complex of Betaine Aldehyde Dehydrogenase from Pseudomonas aeruginosa Provides New Insight into the Reaction Mechanism and Shows A Novel Binding Mode of the 2′-Phosphate of NADP+ and A Novel Cation Binding Site

Defining the DNA Substrate Binding Sites on HIV-1 Integrase

Structural Base for Enzymatic Cyclodextrin Hydrolysis

Halogenated Benzenes Bound within a Non-polar Cavity in T4 Lysozyme Provide Examples of I⋯S and I⋯Se Halogen-bonding

Crystal Structure of the Pml1p Subunit of the Yeast Precursor mRNA Retention and Splicing Complex

The Disulfide Relay System of Mitochondria Is Required for the Biogenesis of Mitochondrial Ccs1 and Sod1

In Silico Vaccine Design Based on Molecular Simulations of Rhinovirus Chimeras Presenting HIV-1 gp41 Epitopes

Diverse Role of Three Tyrosines in Binding of the RNA 5′ Cap to the Human Nuclear Cap Binding Complex

Role of Allosteric Switch Residue Histidine 195 in Maintaining Active-Site Asymmetry in Presynaptic Filaments of Bacteriophage T4 UvsX Recombinase

RosettaLigand Docking with Full Ligand and Receptor Flexibility

Editorial Board

Contents