Campagne de collecte 15 septembre 2024 – 1 octobre 2024 C'est quoi, la collecte de fonds?

Volume 42; Issue 16

Journal of Medicinal Chemistry

Volume 42; Issue 16

1

Lipophilic 4-Isoxazolyl-1,4-dihydropyridines: Synthesis and Structure−Activity Relationships

Natale, Nicholas R., Rogers, Mark E., Staples, Richard, Triggle, David J., Rutledge, Aleta

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 97 KB

english, 1999

2

Nω-Nitroarginine-Containing Dipeptide Amides. Potent and Highly Selective Inhibitors of Neuronal Nitric Oxide Synthase

Huang, Hui, Martasek, Pavel, Roman, Linda J., Masters, Bettie Sue Siler, Silverman, Richard B.

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 107 KB

english, 1999

3

Novel Calcium Antagonists with Both Calcium Overload Inhibition and Antioxidant Activity. 2. Structure−Activity Relationships of Thiazolidinone Derivatives

Kato, Tatsuya, Ozaki, Tomokazu, Tamura, Kazuhiko, Suzuki, Yoshiyuki, Akima, Michitaka, Ohi, Nobuhiro

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 852 KB

english, 1999

4

Robust QSAR Models Using Bayesian Regularized Neural Networks

Burden, Frank R.

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 42 KB

english, 1999

5

Carboxylic Acid Analogues of Tamoxifen: ( Z )-2-[ p -(1,2-Diphenyl-1-butenyl)phenoxy]- N,N -dimethylethylamine. Estrogen Receptor Affinity and Estrogen Antagonist Effects in MCF-7 Cells

Kraft, Kelly S., Ruenitz, Peter C., Bartlett, Michael G.

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 159 KB

english, 1999

6

Synthesis and Characterization of Fluorescent Ligands for the Norepinephrine Transporter: Potential Neuroblastoma Imaging Agents

Hadrich, Dirk, Berthold, Frank, Steckhan, Eberhard, Bönisch, Heinz

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 99 KB

english, 1999

7

Novel Prodrug Approach for Tertiary Amines: Synthesis and Preliminary Evaluation of N -Phosphonooxymethyl Prodrugs

Krise, Jeffrey P., Zygmunt, Jan, Georg, Gunda I., Stella, Valentino J.

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 139 KB

english, 1999

8

N -Methylated Cyclic RGD Peptides as Highly Active and Selective α V β 3 Integrin Antagonists

Dechantsreiter, Michael A., Planker, Eckart, Mathä, Barbara, Lohof, Elisabeth, Hölzemann, Günter, Jonczyk, Alfred, Goodman, Simon L., Kessler, Horst

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 220 KB

english, 1999

9

Chiral Resolution and Stereospecificity of 6-Phenyl-4-phenylethynyl- 1,4-dihydropyridines as Selective A 3 Adenosine Receptor Antagonists

Jiang, Ji-long, Li, An-Hu, Jang, Soo-Yeon, Chang, Louis, Melman, Neli, Moro, Stefano, Ji, Xiao-duo, Lobkovsky, Emil B., Clardy, Jon C., Jacobson, Kenneth A.

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 237 KB

english, 1999

10

Molecular Recognition in Nicotinic Acetylcholine Receptors: The Importance of π−Cation Interactions

Schmitt, Jeffrey D., Sharples, Christopher G. V., Caldwell, W. S.

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 162 KB

english, 1999

11

Ochratoxin Binding to Phenylalanyl-tRNA Synthetase: Computational Approach to the Mechanism of Ochratoxicosis and Its Antagonism

McMasters, Daniel R., Vedani, Angelo

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 205 KB

english, 1999

12

Synthesis, Evaluation, and Comparative Molecular Field Analysis of 1-Phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as Ligands for Histamine H 1 Receptors

Bucholtz, Ehren C., Brown, Randal L., Tropsha, Alexander, Booth, Raymond G., Wyrick, Steven D.

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 175 KB

english, 1999

13

Novel A,B,E-Ring-Modified Camptothecins Displaying High Lipophilicity and Markedly Improved Human Blood Stabilities

Bom, David, Curran, Dennis P., Chavan, Ashok J., Kruszewski, Stefan, Zimmer, Stephen G., Fraley, Kimberly A., Burke, Thomas G.

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 104 KB

english, 1999

14

A Novel Acetylated Analogue of Dynorphin A-(1−11) Amide as a κ-Opioid Receptor Antagonist

Wan, Qiang, Murray, Thomas F., Aldrich, Jane V.

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 67 KB

english, 1999

15

Synthesis and Enantiomeric Separation of 2-Phthalimidino-glutaric Acid Analogues: Potent Inhibitors of Tumor Metastasis

Shah, Jamshed H., Swartz, Glenn M., Papathanassiu, Adonia E., Treston, Anthony M., Fogler, William E., Madsen, John W., Green, Shawn J.

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 169 KB

english, 1999

16

Development of Predictive Retention−Activity Relationship Models of Tricyclic Antidepressants by Micellar Liquid Chromatography

Quiñones-Torrelo, C., Sagrado, S., Villanueva-Camañas, R. M., Medina-Hernández, M. J.

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 204 KB

english, 1999

17

New Type of Febrifugine Analogues, Bearing a Quinolizidine Moiety, Show Potent Antimalarial Activity against Plasmodium Malaria Parasite

Takaya, Yoshiaki, Tasaka, Hidehisa, Chiba, Tomoyuki, Uwai, Koji, Tanitsu, Masa-aki, Kim, Hye-Sook, Wataya, Yusuke, Miura, Masatomo, Takeshita, Mitsuhiro, Oshima, Yoshiteru

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 53 KB

english, 1999

18

Constrained Corticotropin Releasing Factor Antagonists (Astressin Analogues) with Long Duration of Action in the Rat †

Rivier, Jean E., Kirby, Dean A., Lahrichi, Sabine L., Corrigan, Anne, Vale, Wylie W., Rivier, Catherine L.

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 92 KB

english, 1999

19

Synthesis and Biological Activity of the Superestrogen ( E )-17-Oximino-3- O -sulfamoyl-1,3,5(10)-estratriene: X-ray Crystal Structure of ( E )-17-Oximino-3-hydroxy-1,3,5(10)-estratriene

Hejaz, Hatem A. M., Purohit, Atul, Mahon, Mary F., Reed, Michael J., Potter, Barry V. L.

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 119 KB

english, 1999

20

Discovery of 1,6-Naphthyridines as a Novel Class of Potent and Selective Human Cytomegalovirus Inhibitors

Chan, Laval, Jin, Haolun, Stefanac, Tomislav, Lavallée, Jean-François, Falardeau, Guy, Wang, Wei, Bédard, Jean, May, Suzanne, Yuen, Leonard

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 37 KB

english, 1999

21

Potent Bivalent Thrombin Inhibitors: Replacement of the Scissile Peptide Bond at P 1 −P 1 ‘ with Arginyl Ketomethylene Isosteres ∇

Steinmetzer, Torsten, Zhu, Bing Yan, Konishi, Yasuo

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 90 KB

english, 1999

22

Novel Hypotensive Agents from Verbesina ca racasana . 6. Synthesis and Pharmacology of Caracasandiamide 1

Carmignani, Marco, Volpe, Anna R., Delle Monache, Franco, Botta, Bruno, Espinal, Romulo, De Bonnevaux, Stella C., De Luca, Carlo, Botta, Maurizio, Corelli, Federico, Tafi, Andrea, Ripanti, Giuseppe, D

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 170 KB

english, 1999

23

Discovery and Synthesis of ( S )-3-[2-(3,4-Dimethoxyphenyl)ethoxy]-2- (4,6-dimethylpyrimidin-2-yloxy)-3,3-diphenylpropionic Acid (LU 302872), a Novel Orally Active Mixed ET A /ET B Receptor Antagonist

Amberg, Willi, Hergenröder, Stefan, Hillen, Heinz, Jansen, Rolf, Kettschau, Georg, Kling, Andreas, Klinge, Dagmar, Raschack, Manfred, Riechers, Hartmut, Unger, Liliane

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 120 KB

english, 1999

24

Cytotoxicity of 2,2‘:6‘,2‘ ‘-Terpyridineplatinum(II) Complexes against Human Ovarian Carcinoma

Lowe, Gordon, Droz, Anne Sophie, Vilaivan, Tirayut, Weaver, George W., Park, Jenny J., Pratt, Jonathan M., Tweedale, Lindsay, Kelland, Lloyd R.

Journal:

Journal of Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 89 KB

english, 1999