Volume 40; Issue 15

Journal of Medicinal Chemistry

Volume 40; Issue 15

1

2-Cyclopropylindoloquinones and Their Analogues as Bioreductively Activated Antitumor Agents: Structure−Activity in Vitro and Efficacy in Vivo

Naylor, Matthew A., Jaffar, Mohammed, Nolan, John, Stephens, Miriam A., Butler, Susan, Patel, Kantilal B., Everett, Steven A., Adams, Gerald E., Stratford, Ian J.

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 295 KB

english, 1997

2

Structure−Activity Relationships for a Novel Series of Pyrido[2,3-d]pyrimidine Tyrosine Kinase Inhibitors

Hamby, James M., Connolly, Cleo J. C., Schroeder, Mel C., Winters, R. Thomas, Showalter, H. D. Hollis, Panek, Robert L., Major, Terry C., Olsewski, Bronislawa, Ryan, Michael J., Dahring, Tawny

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 171 KB

english, 1997

3

Synthesis of Analogs of 2-Methoxyestradiol with Enhanced Inhibitory Effects on Tubulin Polymerization and Cancer Cell Growth

Cushman, Mark, He, Hu-Ming, Katzenellenbogen, John A., Varma, Ravi K., Hamel, Ernest, Lin, Chii M., Ram, Siya, Sachdeva, Yesh P.

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 404 KB

english, 1997

4

Stabilized Analogs of Thymopentin. 3. Evaluation of Ketomethylene Pseudopeptides for Antiarthritic Properties

Smith, R. Lane, Dousman, Linda, Waud, William R.

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 110 KB

english, 1997

5

A Novel Series of 2,5-Substituted Tryptamine Derivatives as Vascular 5HT 1B/1D Receptor Antagonists

Moloney, Gerard P., Robertson, Alan D., Martin, Graeme R., MacLennan, Steven, Mathews, Neil, Dodsworth, Susan, Sang, Pang Yih, Knight, Cameron, Glen, Robert

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 736 KB

english, 1997

6

A Virtual Screening Approach Applied to the Search for Trypanothione Reductase Inhibitors

Horvath, Dragos

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 336 KB

english, 1997

7

Synthesis and Anti-HIV-1 Activity of a Series of 1-Alkoxy-5-alkyl-6-(arylthio)uracils

Kim, Dae-Kee, Gam, Jongsik, Kim, Young-Woo, Lim, Jinsoo, Kim, Hun-Taek, Kim, Key H.

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 378 KB

english, 1997

8

Stabilized Analogs of Thymopentin. 1. 4,5-Ketomethylene Pseudopeptides

DeGraw, Joseph I., Almquist, Ronald G., Hiebert, Charles K., Colwell, William T., Crase, Jac, Hayano, Takeshi, Judd, Amrit K., Dousman, Linda, Smith, R. Lane, Waud, William R., Uchida, Itsuo

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 381 KB

english, 1997

9

4-Heterocyclylpiperidines as Selective High-Affinity Ligands at the Human Dopamine D4 Receptor

Rowley, Michael, Collins, Ian, Broughton, Howard B., Davey, William B., Baker, Raymond, Emms, Frances, Marwood, Rosemarie, Patel, Shil, Patel, Smita, Ragan, C. Ian, Freedman, Stephen B., Ball, Richard

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 558 KB

english, 1997

10

Synthesis and Nicotinic Acetylcholine Receptor Binding Properties of exo -2-(2‘-Fluoro-5‘-pyridinyl)-7-azabicyclo- [2.2.1]heptane: A New Positron Emission Tomography Ligand for Nicotinic Receptors

Liang, Feng, Navarro, Hernán A., Abraham, Philip, Kotian, Pravin, Ding, Yu-Shin, Fowler, Joanna, Volkow, Nora, Kuhar, Michael J., Carroll, F. Ivy

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 103 KB

english, 1997

11

Discovery of Potent Nonpeptide Vitronectin Receptor (α V β 3 ) Antagonists

Keenan, Richard M., Miller, William H., Kwon, Chet, Ali, Fadia E., Callahan, James F., Calvo, Raul R., Hwang, Shing-Mei, Kopple, Kenneth D., Peishoff, Catherine E., Samanen, James M., Wong, Angela S.,

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 241 KB

english, 1997

12

Designing Combinatorial Library Mixtures Using a Genetic Algorithm

Brown, Robert D., Martin, Yvonne C.

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 202 KB

english, 1997

13

Design, Synthesis, and Biological Evaluation of New Growth Inhibitors of Trypanosoma cruzi (Epimastigotes)

Schvartzapel, Andrea J., Zhong, Li, Docampo, Roberto, Rodriguez, Juan B., Gros, Eduardo G.

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 297 KB

english, 1997

14

Synthesis of Racemic 6,7,8,9-Tetrahydro-3-hydroxy-1 H -1-benzazepine-2,5-diones as Antagonists of N -Methyl- d -aspartate (NMDA) and α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid (AMPA) Receptors

Guzikowski, Anthony P., Whittemore, Edward R., Woodward, Richard M., Weber, Eckard, Keana, John F. W.

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 245 KB

english, 1997

15

Novel Non-Nucleoside Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase. 6. 2-Indol-3-yl- and 2-Azaindol-3-yl- dipyridodiazepinones 1

Kelly, Terence A., McNeil, Daniel W., Rose, Janice M., David, Eva, Shih, Cheng-Kon, Grob, Peter M.

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 164 KB

english, 1997

16

Stabilized Analogs of Thymopentin. 2. 1,2- and 3,4-Ketomethylene Pseudopeptides

DeGraw, Joseph I., Almquist, Ronald G., Hiebert, Charles K., Judd, Amrit K., Dousman, Linda, Smith, R. Lane, Waud, William R., Uchida, Itsuo

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 364 KB

english, 1997

17

Emerging Drugs. The Prospect for Improved Medicines. Annual Executive Briefing. Volume Two. 1997 Edited by William C. Bowman, J. Desmond Fitzgerald, and John B. Taylor. Ashley Publications Ltd, London. 1997. x + 415 pp. 20.5 × 24 cm. ISSN 1361-9195. $640.00; $385.00 (pbk).

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 43 KB

english, 1997