Volume 290; Issue 5

Journal of Biological Chemistry

Volume 290; Issue 5

1

The β-Lactamase Gene Regulator AmpR Is a Tetramer That Recognizes and Binds the d-Ala-d-Ala Motif of Its Repressor UDP- N -acetylmuramic Acid (MurNAc)-pentapeptide

Vadlamani, Grishma, Thomas, Misty D., Patel, Trushar R., Donald, Lynda J., Reeve, Thomas M., Stetefeld, Jörg, Standing, Kenneth G., Vocadlo, David J., Mark, Brian L.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.36 MB

english, 2015

2

Key Importance of Small RNA Binding for the Activity of a Glycine-Tryptophan (GW) Motif-containing Viral Suppressor of RNA Silencing

Pérez-Cañamás, Miryam, Hernández, Carmen

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 5.16 MB

english, 2015

3

A Love Affair with Bacillus subtilis

Losick, Richard

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 997 KB

english, 2015

4

Pompe Disease Results in a Golgi-based Glycosylation Deficit in Human Induced Pluripotent Stem Cell-derived Cardiomyocytes

Raval, Kunil K., Tao, Ran, White, Brent E., De Lange, Willem J., Koonce, Chad H., Yu, Junying, Kishnani, Priya S., Thomson, James A., Mosher, Deane F., Ralphe, John C., Kamp, Timothy J.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 7.80 MB

english, 2015

5

Protein Kinase A Rescues Microtubule Affinity-regulating Kinase 2-induced Microtubule Instability and Neurite Disruption by Phosphorylating Serine 409

Deng, Si-Si, Wu, Le-Yu, Wang, Ya-Chao, Cao, Peng-Rong, Xu, Lei, Li, Qian-Ru, Liu, Meng, Zhang, Lun, Jiang, Yue-Jing, Yang, Xiao-Yu, Sun, Sheng-Nan, Tan, Min-jia, Qian, Min, Zang, Yi, Feng, Linyin, Li,

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.70 MB

english, 2015

6

PLK1 Inhibition Down-regulates Polycomb Group Protein BMI1 via Modulation of the miR-200c/141 Cluster

Dimri, Manjari, Cho, Joon-Ho, Kang, Mingu, Dimri, Goberdhan P.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 4.79 MB

english, 2015

7

Coordinated Regulation of the Orosomucoid-like Gene Family Expression Controls de Novo Ceramide Synthesis in Mammalian Cells

Kiefer, Kerstin, Carreras-Sureda, Amado, García-López, Roberto, Rubio-Moscardó, Fanny, Casas, Josefina, Fabriàs, Gemma, Vicente, Rubén

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 493 KB

english, 2015

8

Calcium-independent Phospholipase A 2 γ Enhances Activation of the ATF6 Transcription Factor during Endoplasmic Reticulum Stress

Elimam, Hanan, Papillon, Joan, Takano, Tomoko, Cybulsky, Andrey V.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.04 MB

english, 2015

9

A+-Helix of Protein C Inhibitor (PCI) Is a Cell-penetrating Peptide That Mediates Cell Membrane Permeation of PCI

Yang, Hanjiang, Wahlmüller, Felix Christof, Sarg, Bettina, Furtmüller, Margareta, Geiger, Margarethe

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.58 MB

english, 2015

10

Structural and Thermodynamic Insights into Chitooligosaccharide Binding to Human Cartilage Chitinase 3-like Protein 2 (CHI3L2 or YKL-39)

Ranok, Araya, Wongsantichon, Jantana, Robinson, Robert C., Suginta, Wipa

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.36 MB

english, 2015

11

Adipocyte-specific Disruption of Fat-specific Protein 27 Causes Hepatosteatosis and Insulin Resistance in High-fat Diet-fed Mice

Tanaka, Naoki, Takahashi, Shogo, Matsubara, Tsutomu, Jiang, Changtao, Sakamoto, Wataru, Chanturiya, Tatyana, Teng, Ruifeng, Gavrilova, Oksana, Gonzalez, Frank J.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 5.15 MB

english, 2015

12

DNA Replication Catalyzed by Herpes Simplex Virus Type 1 Proteins Reveals Trombone Loops at the Fork

Bermek, Oya, Willcox, Smaranda, Griffith, Jack D.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.65 MB

english, 2015

13

Acceleration of α-Synuclein Aggregation by Exosomes

Grey, Marie, Dunning, Christopher J., Gaspar, Ricardo, Grey, Carl, Brundin, Patrik, Sparr, Emma, Linse, Sara

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.39 MB

english, 2015

14

Molecular Interaction between the Chaperone Hsc70 and the N-terminal Flank of Huntingtin Exon 1 Modulates Aggregation

Monsellier, Elodie, Redeker, Virginie, Ruiz-Arlandis, Gemma, Bousset, Luc, Melki, Ronald

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.86 MB

english, 2015

15

p53 Degradation by a Coronavirus Papain-like Protease Suppresses Type I Interferon Signaling

Yuan, Lin, Chen, Zhongbin, Song, Shanshan, Wang, Shan, Tian, Chunyan, Xing, Guichun, Chen, Xiaojuan, Xiao, Zhi-Xiong, He, Fuchu, Zhang, Lingqiang

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.32 MB

english, 2015

16

14-3-3τ Promotes Surface Expression of Cav2.2 (α1B) Ca 2+ Channels

Liu, Feng, Zhou, Qin, Zhou, Jie, Sun, Hao, Wang, Yan, Zou, Xiuqun, Feng, Lingling, Hou, Zhaoyuan, Zhou, Aiwu, Zhou, Yi, Li, Yong

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.34 MB

english, 2015

17

The Essential Autophagy Gene ATG7 Modulates Organ Fibrosis via Regulation of Endothelial-to-Mesenchymal Transition

Singh, Krishna K., Lovren, Fina, Pan, Yi, Quan, Adrian, Ramadan, Azza, Matkar, Pratiek N., Ehsan, Mehroz, Sandhu, Paul, Mantella, Laura E., Gupta, Nandini, Teoh, Hwee, Parotto, Matteo, Tabuchi, Arata,

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.34 MB

english, 2015

18

MicroRNA-146a and MicroRNA-146b Regulate Human Dendritic Cell Apoptosis and Cytokine Production by Targeting TRAF6 and IRAK1 Proteins

Park, Haein, Huang, Xin, Lu, Changming, Cairo, Mitchell S., Zhou, Xianzheng

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.13 MB

english, 2015

19

Mitochondria-associated Endoplasmic Reticulum Membrane (MAM) Regulates Steroidogenic Activity via Steroidogenic Acute Regulatory Protein (StAR)-Voltage-dependent Anion Channel 2 (VDAC2) Interaction

Prasad, Manoj, Kaur, Jasmeet, Pawlak, Kevin J., Bose, Mahuya, Whittal, Randy M., Bose, Himangshu S.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 4.01 MB

english, 2015

20

Identification, Characterization, and Structure Analysis of the Cyclic di-AMP-binding P II -like Signal Transduction Protein DarA

Gundlach, Jan, Dickmanns, Achim, Schröder-Tittmann, Kathrin, Neumann, Piotr, Kaesler, Jan, Kampf, Jan, Herzberg, Christina, Hammer, Elke, Schwede, Frank, Kaever, Volkhard, Tittmann, Kai, Stülke, Jörg,

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.85 MB

english, 2015

21

A Novel Phosphatidylinositol 4,5-Bisphosphate Binding Domain Mediates Plasma Membrane Localization of ExoU and Other Patatin-like Phospholipases

Tyson, Gregory H., Halavaty, Andrei S., Kim, Hyunjin, Geissler, Brett, Agard, Mallory, Satchell, Karla J., Cho, Wonhwa, Anderson, Wayne F., Hauser, Alan R.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 4.58 MB

english, 2015

22

Cytidine Deaminase Motifs within the DYW Domain of Two Pentatricopeptide Repeat-containing Proteins Are Required for Site-specific Chloroplast RNA Editing

Wagoner, Jessica A., Sun, Tao, Lin, Lin, Hanson, Maureen R.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.78 MB

english, 2015

23

Analysis of Mucolipidosis II/III GNPTAB Missense Mutations Identifies Domains of UDP-GlcNAc:lysosomal Enzyme GlcNAc-1-phosphotransferase Involved in Catalytic Function and Lysosomal Enzyme Recognition

Qian, Yi, van Meel, Eline, Flanagan-Steet, Heather, Yox, Alex, Steet, Richard, Kornfeld, Stuart

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.64 MB

english, 2015

24

Salivary Mucin 19 Glycoproteins

Culp, David J., Robinson, Bently, Cash, Melanie N., Bhattacharyya, Indraneel, Stewart, Carol, Cuadra-Saenz, Giancarlo

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.37 MB

english, 2015

25

Apurinic/Apyrimidinic Endonuclease/Redox Factor-1 (APE1/Ref-1) Redox Function Negatively Regulates NRF2

Fishel, Melissa L., Wu, Xue, Devlin, Cecilia M., Logsdon, Derek P., Jiang, Yanlin, Luo, Meihua, He, Ying, Yu, Zhangsheng, Tong, Yan, Lipking, Kelsey P., Maitra, Anirban, Rajeshkumar, N. V., Scandura,

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2015

26

Amitriptyline Improves Motor Function via Enhanced Neurotrophin Signaling and Mitochondrial Functions in the Murine N171-82Q Huntington Disease Model

Cong, Wei-Na, Chadwick, Wayne, Wang, Rui, Daimon, Caitlin M., Cai, Huan, Amma, Jennifer, Wood, William H., Becker, Kevin G., Martin, Bronwen, Maudsley, Stuart

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 4.43 MB

english, 2015

27

RDH13L, an Enzyme Responsible for the Aldehyde-Alcohol Redox Coupling Reaction (AL-OL Coupling Reaction) to Supply 11- cis Retinal in the Carp Cone Retinoid Cycle

Sato, Shinya, Miyazono, Sadaharu, Tachibanaki, Shuji, Kawamura, Satoru

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.09 MB

english, 2015

28

Crosstalking between Androgen and PI3K/AKT Signaling Pathways in Prostate Cancer Cells

Lee, Suk Hyung, Johnson, Daniel, Luong, Richard, Sun, Zijie

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 5.56 MB

english, 2015

29

Mechanistic Analysis of the Role of Bromodomain-containing Protein 4 (BRD4) in BRD4-NUT Oncoprotein-induced Transcriptional Activation

Wang, Ranran, You, Jianxin

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 4.18 MB

english, 2015

30

PINK1 Kinase Catalytic Activity Is Regulated by Phosphorylation on Serines 228 and 402

Aerts, Liesbeth, Craessaerts, Katleen, De Strooper, Bart, Morais, Vanessa A.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.97 MB

english, 2015

31

Demonstration of the Trombone Model in the DNA Replication of the Herpes Simplex Virus Type 1♦:

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 819 KB

english, 2015

32

The Paired Basic Amino Acid-cleaving Enzyme 4 (PACE4) Is Involved in the Maturation of Insulin Receptor Isoform B

Kara, Imène, Poggi, Marjorie, Bonardo, Bernadette, Govers, Roland, Landrier, Jean-François, Tian, Sun, Leibiger, Ingo, Day, Robert, Creemers, John W. M., Peiretti, Franck

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.59 MB

english, 2015

33

Reduced Sialylation Impacts Ventricular Repolarization by Modulating Specific K + Channel Isoforms Distinctly

Ednie, Andrew R., Bennett, Eric S.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.20 MB

english, 2015

34

Structural Basis for the Disruption of the Cerebral Cavernous Malformations 2 (CCM2) Interaction with Krev Interaction Trapped 1 (KRIT1) by Disease-associated Mutations

Fisher, Oriana S., Liu, Weizhi, Zhang, Rong, Stiegler, Amy L., Ghedia, Sondhya, Weber, James L., Boggon, Titus J.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.38 MB

english, 2015

35

Structural Model of the Cytosolic Domain of the Plant Ethylene Receptor 1 (ETR1)

Mayerhofer, Hubert, Panneerselvam, Saravanan, Kaljunen, Heidi, Tuukkanen, Anne, Mertens, Haydyn D. T., Mueller-Dieckmann, Jochen

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 4.67 MB

english, 2015

36

Site-directed Mutagenesis Reveals Regions Implicated in the Stability and Fiber Formation of Human λ3r Light Chains

Villalba, Miryam I., Canul-Tec, Juan C., Luna-Martínez, Oscar D., Sánchez-Alcalá, Rosalba, Olamendi-Portugal, Timoteo, Rudiño-Piñera, Enrique, Rojas, Sonia, Sánchez-López, Rosana, Fernández-Velasco, D

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 5.18 MB

english, 2015

37

Naturally Processed Non-canonical HLA-A*02:01 Presented Peptides

Hassan, Chopie, Chabrol, Eric, Jahn, Lorenz, Kester, Michel G. D., de Ru, Arnoud H., Drijfhout, Jan W., Rossjohn, Jamie, Falkenburg, J. H. Frederik, Heemskerk, Mirjam H. M., Gras, Stephanie, van Veele

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.64 MB

english, 2015

38

Phosphorylation of Ezrin-Radixin-Moesin-binding Phosphoprotein 50 (EBP50) by Akt Promotes Stability and Mitogenic Function of S-phase Kinase-associated Protein-2 (Skp2)

Song, Gyun Jee, Leslie, Kristen L., Barrick, Stacey, Mamonova, Tatyana, Fitzpatrick, Jeremy M., Drombosky, Kenneth W., Peyser, Noah, Wang, Bin, Pellegrini, Maria, Bauer, Philip M., Friedman, Peter A.,

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.83 MB

english, 2015

39

The Use of Carbohydrate Binding Modules (CBMs) to Monitor Changes in Fragmentation and Cellulose Fiber Surface Morphology during Cellulase- and Swollenin-induced Deconstruction of Lignocellulosic Substrates

Gourlay, Keith, Hu, Jinguang, Arantes, Valdeir, Penttilä, Merja, Saddler, Jack N.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.46 MB

english, 2015

40

Determinants of Endogenous Ligand Specificity Divergence among Metabotropic Glutamate Receptors

Kang, Hye Jin, Wilkins, Angela D., Lichtarge, Olivier, Wensel, Theodore G.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.95 MB

english, 2015

41

Structural and Inhibitory Effects of Hinge Loop Mutagenesis in Serpin-2 from the Malaria Vector Anopheles gambiae

Zhang, Xin, Meekins, David A., An, Chunju, Zolkiewski, Michal, Battaile, Kevin P., Kanost, Michael R., Lovell, Scott, Michel, Kristin

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.57 MB

english, 2015

42

A Gut Microbial Metabolite of Linoleic Acid, 10-Hydroxy- cis -12-octadecenoic Acid, Ameliorates Intestinal Epithelial Barrier Impairment Partially via GPR40-MEK-ERK Pathway

Miyamoto, Junki, Mizukure, Taichi, Park, Si-Bum, Kishino, Shigenobu, Kimura, Ikuo, Hirano, Kanako, Bergamo, Paolo, Rossi, Mauro, Suzuki, Takuya, Arita, Makoto, Ogawa, Jun, Tanabe, Soichi

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.97 MB

english, 2015

43

Fancd2 Is Required for Nuclear Retention of Foxo3a in Hematopoietic Stem Cell Maintenance

Li, Xiaoli, Li, Jie, Wilson, Andrew, Sipple, Jared, Schick, Jonathan, Pang, Qishen

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.36 MB

english, 2015

44

The TRPM8 Protein Is a Testosterone Receptor

Asuthkar, Swapna, Demirkhanyan, Lusine, Sun, Xiaohui, Elustondo, Pia A., Krishnan, Vivek, Baskaran, Padmamalini, Velpula, Kiran Kumar, Thyagarajan, Baskaran, Pavlov, Evgeny V., Zakharian, Eleonora

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 7.80 MB

english, 2015

45

HTRA1 (High Temperature Requirement A Serine Peptidase 1) Gene Is Transcriptionally Regulated by Insertion/Deletion Nucleotides Located at the 3′ End of the ARMS2 (Age-related Maculopathy Susceptibility 2) Gene in Patients with Age-related Macular Degeneration

Iejima, Daisuke, Itabashi, Takeshi, Kawamura, Yuich, Noda, Toru, Yuasa, Shinsuke, Fukuda, Keiichi, Oka, Chio, Iwata, Takeshi

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.89 MB

english, 2015

46

The TRPM8 Protein Is a Testosterone Receptor

Asuthkar, Swapna, Elustondo, Pia A., Demirkhanyan, Lusine, Sun, Xiaohui, Baskaran, Padmamalini, Velpula, Kiran Kumar, Thyagarajan, Baskaran, Pavlov, Evgeny V., Zakharian, Eleonora

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 6.28 MB

english, 2015

47

Gonadotrope-specific Deletion of Dicer Results in Severely Suppressed Gonadotropins and Fertility Defects

Wang, Huizhen, Graham, Ian, Hastings, Richard, Gunewardena, Sumedha, Brinkmeier, Michelle L., Conn, P. Michael, Camper, Sally A., Kumar, T. Rajendra

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 5.29 MB

english, 2015

48

Functional Characterization of Ca V α2δ Mutations Associated with Sudden Cardiac Death

Bourdin, Benoîte, Shakeri, Behzad, Tétreault, Marie-Philippe, Sauvé, Rémy, Lesage, Sylvie, Parent, Lucie

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 7.14 MB

english, 2015

49

Identification of Significant Amino Acids in Multiple Transmembrane Domains of Human Transient Receptor Potential Ankyrin 1 (TRPA1) for Activation by Eudesmol, an Oxygenized Sesquiterpene in Hop Essential Oil

Ohara, Kazuaki, Fukuda, Takafumi, Okada, Hiroyuki, Kitao, Sayoko, Ishida, Yuko, Kato, Kyoko, Takahashi, Chika, Katayama, Mikio, Uchida, Kunitoshi, Tominaga, Makoto

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 526 KB

english, 2015

50

Complex Structure and Biochemical Characterization of the Staphylococcus aureus Cyclic Diadenylate Monophosphate (c-di-AMP)-binding Protein PstA, the Founding Member of a New Signal Transduction Protein Family

Campeotto, Ivan, Zhang, Yong, Mladenov, Miroslav G., Freemont, Paul S., Gründling, Angelika

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 7.25 MB

english, 2015

51

Angiotensin II Type I and Prostaglandin F2α Receptors Cooperatively Modulate Signaling in Vascular Smooth Muscle Cells

Goupil, Eugénie, Fillion, Dany, Clément, Stéphanie, Luo, Xiaoyan, Devost, Dominic, Sleno, Rory, Pétrin, Darlaine, Saragovi, H. Uri, Thorin, Éric, Laporte, Stéphane A., Hébert, Terence E.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2015

52

Prolyl Isomerization as a Molecular Memory in the Allosteric Regulation of the Signal Adapter Protein c-CrkII

Schmidpeter, Philipp A. M., Schmid, Franz X.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2015