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Volume 290; Issue 38

Journal of Biological Chemistry

Volume 290; Issue 38

1

DNA End Resection: Nucleases Team Up with the Right Partners to Initiate Homologous Recombination

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2015

2

Matrix Metalloproteinase (MMP) Proteolysis of the Extracellular Loop of Voltage-gated Sodium Channels and Potential Alterations in Pain Signaling

Remacle, Albert G., Kumar, Sonu, Motamedchaboki, Khatereh, Cieplak, Piotr, Hullugundi, Swathi, Dolkas, Jennifer, Shubayev, Veronica I., Strongin, Alex Y.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.86 MB

english, 2015

3

Deletion of Phenylalanine 508 in the First Nucleotide-binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator Increases Conformational Exchange and Inhibits Dimerization

Chong, P. Andrew, Farber, Patrick J., Vernon, Robert M., Hudson, Rhea P., Mittermaier, Anthony K., Forman-Kay, Julie D.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 5.04 MB

english, 2015

4

Tim62, a Novel Mitochondrial Protein in Trypanosoma brucei , Is Essential for Assembly and Stability of the TbTim17 Protein Complex

Singha, Ujjal K., Hamilton, VaNae, Chaudhuri, Minu

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.31 MB

english, 2015

5

Glioblastoma-derived Macrophage Colony-stimulating Factor (MCSF) Induces Microglial Release of Insulin-like Growth Factor-binding Protein 1 (IGFBP1) to Promote Angiogenesis

Nijaguna, Mamatha Bangalore, Patil, Vikas, Urbach, Serge, Shwetha, Shivayogi D., Sravani, Kotha, Hegde, Alangar S., Chandramouli, Bangalore A., Arivazhagan, Arimappamagan, Marin, Philippe, Santosh, Va

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 4.00 MB

english, 2015

6

MicroRNAs in the Myocyte Enhancer Factor 2 (MEF2)-regulated Gtl2-Dio3 Noncoding RNA Locus Promote Cardiomyocyte Proliferation by Targeting the Transcriptional Coactivator Cited2

Clark, Amanda L., Naya, Francisco J.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.88 MB

english, 2015

7

Excess Linoleic Acid Increases Collagen I/III Ratio and “Stiffens” the Heart Muscle Following High Fat Diets

Beam, Julianne, Botta, Amy, Ye, Jiayu, Soliman, Hesham, Matier, Brieanne J., Forrest, Mary, MacLeod, Kathleen M., Ghosh, Sanjoy

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.08 MB

english, 2015

8

Nuclear Calcium Buffering Capacity Shapes Neuronal Architecture

Mauceri, Daniela, Hagenston, Anna M., Schramm, Kathrin, Weiss, Ursula, Bading, Hilmar

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.56 MB

english, 2015

9

Hyaluronan and Its Heavy Chain Modification in Asthma Severity and Experimental Asthma Exacerbation

Lauer, Mark E., Majors, Alana K., Comhair, Suzy, Ruple, Lisa M., Matuska, Brittany, Subramanian, Ahila, Farver, Carol, Dworski, Ryszard, Grandon, Deepa, Laskowski, Dan, Dweik, Raed A., Erzurum, Serpil

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 4.10 MB

english, 2015

10

Phosphorylation of Tyrosine 1070 at the GluN2B Subunit Is Regulated by Synaptic Activity and Critical for Surface Expression of N -Methyl-d-aspartate (NMDA) Receptors

Lu, Wen, Fang, Weiqing, Li, Jian, Zhang, Bin, Yang, Qian, Yan, Xunyi, Peng, Lin, Ai, Heng, Wang, Jie-jie, Liu, Xiao, Luo, Jianhong, Yang, Wei

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.71 MB

english, 2015

11

Plasma Membrane Tetraspanin CD81 Complexes with Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR), and Its Levels Are Reduced by PCSK9

Le, Quoc-Tuan, Blanchet, Matthieu, Seidah, Nabil G., Labonté, Patrick

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.79 MB

english, 2015

12

Saccharomyces cerevisiae Sen1 Helicase Domain Exhibits 5′- to 3′-Helicase Activity with a Preference for Translocation on DNA Rather than RNA

Martin-Tumasz, Stephen, Brow, David A.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.50 MB

english, 2015

13

Positive and Negative Allosteric Modulation of an α1β3γ2 γ-Aminobutyric Acid Type A (GABA A ) Receptor by Binding to a Site in the Transmembrane Domain at the γ + -β − Interface

Jayakar, Selwyn S., Zhou, Xiaojuan, Savechenkov, Pavel Y., Chiara, David C., Desai, Rooma, Bruzik, Karol S., Miller, Keith W., Cohen, Jonathan B.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 6.68 MB

english, 2015

14

Sphingosine Kinase 1 Protects Hepatocytes from Lipotoxicity via Down-regulation of IRE1α Protein Expression

Qi, Yanfei, Wang, Wei, Chen, Jinbiao, Dai, Lan, Kaczorowski, Dominik, Gao, Xin, Xia, Pu

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.02 MB

english, 2015

15

Identification of Novel 14-3-3 Residues That Are Critical for Isoform-specific Interaction with GluN2C to Regulate N -Methyl-d-aspartate (NMDA) Receptor Trafficking

Chung, Connie, Wu, Wei-Hua, Chen, Bo-Shiun

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.95 MB

english, 2015

16

Signal Transduction by BvgS Sensor Kinase

Dupré, Elian, Lesne, Elodie, Guérin, Jérémy, Lensink, Marc F., Verger, Alexis, de Ruyck, Jérôme, Brysbaert, Guillaume, Vezin, Hervé, Locht, Camille, Antoine, Rudy, Jacob-Dubuisson, Françoise

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.00 MB

english, 2015

17

Structural Determinants for Substrate Binding and Catalysis in Triphosphate Tunnel Metalloenzymes

Martinez, Jacobo, Truffault, Vincent, Hothorn, Michael

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.61 MB

english, 2015

18

Molecular Insights into Inhibition of the Methylated Histone-Plant Homeodomain Complexes by Calixarenes

Ali, Muzaffar, Daze, Kevin D., Strongin, Daniel E., Rothbart, Scott B., Rincon-Arano, Hector, Allen, Hillary F., Li, Janessa, Strahl, Brian D., Hof, Fraser, Kutateladze, Tatiana G.

Journal:

Journal of Biological Chemistry

Année:

2015

Fichier:

PDF, 4.00 MB

2015

19

Molecular Insights into Inhibition of the Methylated Histone-Plant Homeodomain Complexes by Calixarenes

Ali, Muzaffar, Daze, Kevin D., Strongin, Daniel E., Rothbart, Scott B., Rincon-Arano, Hector, Allen, Hillary F., Li, Janessa, Strahl, Brian D., Hof, Fraser, Kutateladze, Tatiana G.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 4.00 MB

english, 2015

20

Probing the Catalytic Mechanism of Copper Amine Oxidase from Arthrobacter globiformis with Halide Ions

Murakawa, Takeshi, Hamaguchi, Akio, Nakanishi, Shota, Kataoka, Misumi, Nakai, Tadashi, Kawano, Yoshiaki, Yamaguchi, Hiroshi, Hayashi, Hideyuki, Tanizawa, Katsuyuki, Okajima, Toshihide

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.52 MB

english, 2015

21

Dihydrofolate Reductase and Thymidylate Synthase Transgenes Resistant to Methotrexate Interact to Permit Novel Transgene Regulation

Rushworth, David, Mathews, Amber, Alpert, Amir, Cooper, Laurence J. N.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 762 KB

english, 2015

22

Changes in Structural-Mechanical Properties and Degradability of Collagen during Aging-associated Modifications

Panwar, Preety, Lamour, Guillaume, Mackenzie, Neil C. W., Yang, Heejae, Ko, Frank, Li, Hongbin, Brömme, Dieter

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 8.47 MB

english, 2015

23

Heparan sulfate is required for embryonic stem cells to exit from self-renewal.:

Kraushaar, Daniel C., Yamaguchi, Yu, Wang, Lianchun

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 647 KB

english, 2015

24

Single and Compound Knock-outs of MicroRNA (miRNA)-155 and Its Angiogenic Gene Target CCN1 in Mice Alter Vascular and Neovascular Growth in the Retina via Resident Microglia

Yan, Lulu, Lee, Sangmi, Lazzaro, Douglas R., Aranda, Jacob, Grant, Maria B., Chaqour, Brahim

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 8.88 MB

english, 2015

25

Structural Aspects of N -Glycosylations and the C-terminal Region in Human Glypican-1

Awad, Wael, Adamczyk, Barbara, Örnros, Jessica, Karlsson, Niclas G., Mani, Katrin, Logan, Derek T.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 4.64 MB

english, 2015

26

Characterization of P4 ATPase Phospholipid Translocases (Flippases) in Human and Rat Pancreatic Beta Cells

Ansari, Israr-ul H., Longacre, Melissa J., Paulusma, Coen C., Stoker, Scott W., Kendrick, Mindy A., MacDonald, Michael J.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 2.05 MB

english, 2015

27

Characterization of Dye-decolorizing Peroxidase (DyP) from Thermomonospora curvata Reveals Unique Catalytic Properties of A-type DyPs

Chen, Chao, Shrestha, Ruben, Jia, Kaimin, Gao, Philip F., Geisbrecht, Brian V., Bossmann, Stefan H., Shi, Jishu, Li, Ping

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 6.24 MB

english, 2015

28

Modulation of Glucagon Receptor Pharmacology by Receptor Activity-modifying Protein-2 (RAMP2)

Weston, Cathryn, Lu, Jing, Li, Naichang, Barkan, Kerry, Richards, Gareth O., Roberts, David J., Skerry, Timothy M., Poyner, David, Pardamwar, Meenakshi, Reynolds, Christopher A., Dowell, Simon J., Wil

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.39 MB

english, 2015

29

Tuning of Pectin Methylesterification

Sénéchal, Fabien, L'Enfant, Mélanie, Domon, Jean-Marc, Rosiau, Emeline, Crépeau, Marie-Jeanne, Surcouf, Ogier, Esquivel-Rodriguez, Juan, Marcelo, Paulo, Mareck, Alain, Guérineau, François, Kim, Hyung-

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 4.12 MB

english, 2015

30

Regulation of RNF144A E3 Ubiquitin Ligase Activity by Self-association through Its Transmembrane Domain

Ho, Shiuh-Rong, Lee, Yu-Ju, Lin, Weei-Chin

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 4.19 MB

english, 2015

31

Hierarchal Autophagic Divergence of Hematopoietic System

Cao, Yan, Zhang, Suping, Yuan, Na, Wang, Jian, Li, Xin, Xu, Fei, Lin, Weiwei, Song, Lin, Fang, Yixuan, Wang, Zhijian, Wang, Zhen, Zhang, Han, Zhang, Yi, Zhao, Wenli, Hu, Shaoyan, Zhang, Xueguang, Wang

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 4.24 MB

english, 2015

32

A Mutation in Transmembrane Domain 7 (TM7) of Excitatory Amino Acid Transporters Disrupts the Substrate-dependent Gating of the Intrinsic Anion Conductance and Drives the Channel into a Constitutively Open State

Torres-Salazar, Delany, Jiang, Jie, Divito, Christopher B., Garcia-Olivares, Jennie, Amara, Susan G.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.30 MB

english, 2015

33

Mechanism of Fine-tuning pH Sensors in Proprotein Convertases

Williamson, Danielle M., Elferich, Johannes, Shinde, Ujwal

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.15 MB

english, 2015

34

High-resolution Digital Mapping of N -Methylpurines in Human Cells Reveals Modulation of Their Induction and Repair by Nearest-neighbor Nucleotides

Li, Mingyang, Ko, Tengyu, Li, Shisheng

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 4.32 MB

english, 2015

35

Probing the solution structure of IκB kinase (IKK) subunit γ and its interaction with Kaposi sarcoma-associated herpes virus Flice-interacting protein and IKK subunit β by EPR spectroscopy.

Bagnéris, Claire, Rogala, Kacper B., Baratchian, Mehdi, Zamfir, Vlad, Kunze, Micha B. A., Dagless, Selina, Pirker, Katharina F., Collins, Mary K., Hall, Benjamin A., Barrett, Tracey E., Kay, Christoph

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 191 KB

english, 2015

36

Revealing the Mechanism of Function for a Helicase Implicated in Neurodegenerative Disorders ♦

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 411 KB

english, 2015

37

Deletion of Phenylalanine 508 in the Cystic Fibrosis Transmembrane Conductance Regulator Reduces Dimerization ♦

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 397 KB

english, 2015

38

The Bordetella adenylate cyclase repeat-in-toxin (RTX) domain is immunodominant and elicits neutralizing antibodies.

Wang, Xianzhe, Gray, Mary C., Hewlett, Erik L., Maynard, Jennifer A.

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 47 KB

english, 2015