Poly(ADP-ribose) glycohydrolase inhibition sequesters NAD+ to potentiate the metabolic lethality of alkylating chemotherapy in IDH mutant tumor cells
Nagashima, Hiroaki, Lee, Christine K, Tateishi, Kensuke, Higuchi, Fumi, Subramanian, Megha, Rafferty, Seamus, Melamed, Lisa, Miller, Julie J., Wakimoto, Hiroaki, Cahill, Daniel P.Journal:
Cancer Discovery
DOI:
10.1158/2159-8290.CD-20-0226
Date:
June, 2020
Fichier:
PDF, 14.98 MB
2020
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