Structure-Based Drug Discovery of N-((R)-3-(7-Methyl-1H-indazol-5-yl)-1-oxo-1-(((S)-1-oxo-3-(piperidin-4-yl)-1-(4-(pyridin-4-yl)piperazin-1-yl)propan-2-yl)amino)propan-2-yl)-2'-oxo-1',2'-dihydrospiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazine]-1-carboxamide (HTL22562): a Calcitonin Gene-Related Peptide (CGRP) Receptor Antagonist For Acute Treatment of Migraine
Bucknell, Sarah Joanne, Ator, Mark A, Brown, Alastair, Brown, Jason, Cansfield, Andrew, Cansfield, Julie, Christopher, John, Congreve, Miles, Cseke, Gabriella, Deflorian, Francesca, Jones, ChristopherJournal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.0c01003
Date:
June, 2020
Fichier:
PDF, 903 KB
2020
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