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Structure-based design and pharmacokinetic optimization of covalent allosteric inhibitors of the mutant GTPase KRAS G12C
Kettle, Jason Grant, Bagal, Sharan, Bickerton, Sue, Bodnarchuk, Michael Steven, Breed, Jason, Carbajo, Rodrigo J., Cassar, Doyle, Chakraborty, Atanu, Cosulich, Sabina, Cumming, Iain, Davies, Michael,Langue:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.9b01720
Date:
February, 2020
Fichier:
PDF, 1.12 MB
english, 2020