Incorporation of Agouti-Related Protein (AgRP) Human Single Nucleotide Polymorphisms (SNPs) in the AGRP-Derived Macrocyclic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe-DPro] Decreases Melanocortin-4 Receptor Antagonist Potency and Results in the Discovery of Melanocortin-5 Receptor Antagonists
Koerperich, Zoe M., Ericson, Mark D., Freeman, Katie T., Speth, Robert, Pogozheva, Irina D., Mosberg, Henry I., Haskell-Luevano, CarrieJournal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.9b00860
Date:
December, 2019
Fichier:
PDF, 1.09 MB
2019
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