Synthesis and Pharmacological Characterization of 2-(2,6-dichlorophenyl)-1-((1S,3R)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one (LY3154207), a potent, subtype selective, and orally available positive allosteric modulator of the human dopamine D1 receptor
Hao, Junliang, Beck, James P, Schaus, Johm M, Krushinski, Joseph H, Chen, Qi, Beadle, Christopher D, Vidal, Paloma, Reinhard, Matthew R, Dressman, Bruce A, Massey, Steven M, Boulet, Serge L, Cohen, MiLangue:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.9b01234
Date:
September, 2019
Fichier:
PDF, 1.21 MB
english, 2019
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