
Improved prediction of in vivo supersaturation and precipitation of poorly soluble weakly basic drugs using a biorelevant bicarbonate buffer in a GI transfer model
Jede, Christian, Wagner, Christian, Kubas, Holger, Weigandt, Markus, Weber, Christian, Lecomte, Marc, Badolo, Lassina, Koziolek, Mirko, Weitschies, WernerLangue:
english
Journal:
Molecular Pharmaceutics
DOI:
10.1021/acs.molpharmaceut.9b00534
Date:
July, 2019
Fichier:
PDF, 484 KB
english, 2019