Brain accumulation of osimertinib and its active metabolite AZ5104 is restricted by ABCB1 (P-glycoprotein) and ABCG2 (Breast Cancer Resistance Protein)
van Hoppe, Stéphanie, Jamalpoor, Amer, Rood, Johannes J.M., Wagenaar, Els, Sparidans, Rolf W., Beijnen, Jos H., Schinkel, Alfred H.Langue:
english
Journal:
Pharmacological Research
DOI:
10.1016/j.phrs.2019.104297
Date:
June, 2019
Fichier:
PDF, 862 KB
english, 2019
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